Uh oh–we need to talk about NP Thyroid by Acella

Please note before reading the below: As you read the below, understand that we are in an exploration state in this horrendous new development. But there have been clear changes to NP which you will see once you read all the comments. Yes, there are patients who weren’t optimal before picking up the changed tablets, and yes, not being optimal can mean their symptoms were from that. BUT…we also have a lot of people who have gone noticeably downhill since starting the changed NP tablets, whether they were, or weren’t, optimal before starting on the changed tablets. We are SICK about this when NP was SUCH a good NDT.

SEE MORE DATED UPDATES AT THE BOTTOM OF THE POST. They will be posted as we get them.

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Thanks to patient Emily who took this photo. Former NP
pill on left; changed NP pill on right.

Comments have been coming in by some patients who are using NP Thyroid by Acella. And by those comments, it appears that NP has changed as of this summer 2019…as reported by patients who picked up a new bottle refill and started it. There are three common comments:

  1. It now smells and tastes horrible, worse then before.
  2. The tablets look different from previous ones
  3. I’m feeling much worse now on the same dose that made me feel great. Symptoms are back.

And it’s #3 that is especially concerning. .

This now makes FOUR natural desiccated thyroid products over the last few years that have changed visually and symptomatically. Why??

  • Canada’s version of NDT made by Erfa and called just Thyroid. That was followed by widespread reports of a return of hypo symptoms.
  • Armour after it was bought out from Forest and acquired by Activas Pharmaceuticals–many reported a huge return of their hypo
  • RLC’s Naturethroid, and it frankly went WAY downhill in effect in 2018 as expressed widespread by disappointed patients. We’re still not sure about WP.
  • NP Thyroid by Acella

And you know what else is common with all four pharmaceuticals?? They state “We changed nothing”. So what is going on?

ANALYZING THE COMPLAINTS ABOUT NP

THE SMELL, THE TASTE:

Ugh.

Yes, most NDT’s can smell. lol. It’s pork! But the reaction of patients, when they have started to take the “changed” NP Thyroid, is profound. “It tastes horrible!” “It smells far worse!” Other descriptions: “It tastes like insecticide.” “It tastes rancid.” “It makes me want to gag.”

Now we do know that a batch of NDT is made up of many pigs. And it’s possible that different mixes of pigs could produce different strength of smell. So is Acella using a particularly “stinky” batch of pigs now?? Maybe. Just the change in smell and taste is not indicative of a problem…

THE TABLET:

Boy, here we go again. The visual change is very similar to what we saw with Armour. It’s also similar with what we saw with Naturethroid. There are now specks on the newer current version, and some patients say the edges are rougher. Definitely a different color, too.

Former NP Thyroid tablet on left. Changed NP tablet on right.

In a way, these visual changes would be no big deal. But they could become a big deal when some patients, (who were optimal) are reporting a return of their hypothyroid symptoms and/or feeling awful since being on the changed NP Thyroid. And why is this not the first time that we started seeing specks in different pharmaceutical versions over recent few years?

FEELING WORSE SINCE BEING ON THE NEW TABLET:

This represents the most alarming of comments. We are seeing some people who were OPTIMAL and had been for a long while, only to comment that they now feel much worse since starting on the new tablets. Symptoms range from migraines, feeling tired, sluggish, feeling awful, depression, late afternoon fatigue, feeling like the flu, nausea, hair loss, napping again…etc. Again, we are saying some. Others report still feeling good. But are they on the “changed” tablets? Looks like they are. So we are continuing to try and learn what is going on in the face of pharmaceutical secrecy and the inane need to CHANGE what was already good enough.

Here is one of many examples of how patients are now going downhill on NP. It’s provided by permission from Liz: I take 4 60 mg tabs a day, no thyroid, treated iron and adrenals and finally was doing good and steadily weight was coming off. I have been taking my last refill for about a month now, and when I first opened it noticed the horrid smell, tasted different too. Anyway, the last couple of weeks I’ve felt really fatigued, low energy, hungry all the time, weight creeping back up and bloated.

And here is how one patient sees all this, closely resembling how many are feeling: I’ve had it with all the mystery, secrecy, deception, and lack of transparency that are ultimately badly damaging many, many people’s (mostly women’s) health and lives. And then that affects the lives of all those people’s families in a trickle-down domino effect. Those pharma companies and their associates are obviously not in it for any type of benevolent reason. They obviously don’t care about us. All they care about is money and their own interests. That’s sick (no pun intended), unethical, immoral, inhumane, and lacking in conscience.

In the meantime, for those who have gone downhill, these are options to consider:
1) [This initially suggested raising the changed NP tablets. It appears now that it’s not a viable option when the tablets have been making people so sick]
2) Crush the tablets before swallowing. One gal said she made the changed Armour tablets work this way. A sweetener of choice could be added to tolerate what is being described as a horrid taste
3) Move to Armour. Yes, it’s expensive and there are more fillers. And we just aren’t sure about it anymore.
4) Move to synthetic T3 with synthetic T4 (one grain of NP was 38 mcg T4 and 9 mcg T3 to help find the equivalent amount.) And remember we still have to be optimal even on both synthetics.
5) Move to over-the-counter NDT “supplements” No, we don’t really know how much of T4 and T3 are in them. It’s a matter of watching the labs free T3 and free T4 to find one’s optimal amount.

SO WE WANT TO HEAR FROM YOU, YOUR experience moving from the former good tablets and feel goods (those were were clearly optimal before the change are good gauges) to the newer tablets! Above you will see what “newer” is. And please, make it clear if you were OPTIMAL before you got on the new tablets (free T3 towards the top part of the range; free T4 midrange. Both.) or not. Lot numbers of your changed tablets are good information too, if you have it. Plus when you started on them. Etc.

AFTER you have read this post, and you know you have the changed tablets, go here to report on the lot number and/or expiration date. It’s just a way to figure things out. https://stopthethyroidmadness.com/2019/09/04/part-2-lot-numbers-or-expiration-dates/

The differences between the former tablets and new tablets. Thanks to thyroid patient Sara for allowing me to post this!!

UPDATE #1 on August 24th: So far, it appears that negative changes may have started in May, 2019 for some. But we don’t yet have proof that the changed tablets were coming out in May. We will continue watching for comments.

UPDATE #2 on August 26th: There are many reports about swine fever (not swine flu) killing plenty of pigs in China and into neighboring countries. Here is one. But that can end up being more about price increases. We still don’t have a definitive answer why the size of the NP pill changed, why the smell and taste is far worse, and why so many are seeing a return of their symptoms.

UPDATE #3 August 27th: A request has been made from Acella for the LOT NUMBERS of the CHANGED tablets…NOT the ones that are working.

UPDATE #4 September 13th: There is so much speculation and rumor out there as to why this has happened to NP Thyroid that it’s crazy. No matter what you hear, we do NOT know why this happened and NOTHING is concrete. On the good side, there does appear to be evidence from patients who are talking to Acella that Acella is looking into this. We can only hope.

Important note: STTM is an information-only site based on what many patients worldwide have reported in their treatment and wisdom over the years. This is not to be taken as personal medical advice, nor to replace a relationship with your doctor. By reading this information-only website, you take full responsibility for what you choose to do with this website's information or outcomes. See the Disclaimer and Terms of Use.

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742 Responses to “Uh oh–we need to talk about NP Thyroid by Acella”

  1. Judy

    You can send the pills to Valisure. For a fee they will analyze them for you. The cost depends on the test you select You would need to register online. You can also call customer service and speak to someone, that will help you select the test. You can also transfer your prescription by calling them. If you have a NP thyroid prescription that is due for a refill. When you transfer to them and they will check the pills before mailing them to you. You get a certificate with a breakdown of what they check for. They do this with all prescription ordered by them. And yes, they do have thyroid medication. They can order for you. I checked and they do order NPThyroid This would be a good way of having the pills analyzed without having to pay a fee. It’s included with every prescription they fill for you. Check their website.

    Reply
  2. Karen

    Ok in our search for what is wrong with all ndt.I found this the pigs are fed ractopamine.to make them grow fast Google the effects it has it is pretty scary.it is band in many countries but not the USA.i for one after reading the this will eat pork.on side effect that caught my attention was burning of the throat and stomach and heart problems. Read what it does to pigs is horrible.

    Reply
  3. Sarie

    New Labs on NP Thyroid:

    I’ve been on the new NP for 3 weeks now and have been optimal a little over a year. I seemed to be one of few that wasn’t feeling any symptoms returning, etc. I feel best with my T3 slightly over range, and my Naturopath is good with that 💗 Both sets of lab results are on 5.5 grains NP Thyroid, but 2 grains of the old (good) batch, 3.5 grains new. I’m not sure what to do at this point as I feel as I always have being optimal, and so far labs are stable, although they did drop very slightly 🤔 I tanked miserably and immediately back on the new Nature Throid (4 grains) with tanked Frees and a TSH of 80, and was extremely sick. I’m going to recheck labs again in a few weeks.

    I understand that I’m not taking 100% of the new batch. But when I need 5.5 grains, I’m technically only getting 2 grains of the old, good NP. Based on my past and horrible experience with Nature Throid, I would think that only getting 2 grains of the old NP that I would still feel very sick and see symptoms return. And I would think labs would drop much more significantly with taking the 3.5 grains of the new batch that many are not doing well with. I’m monitoring myself very closely. I’m due to pick up my 2 grain prescription soon so I will be fully on the new batches. I did have a full week out of the 3 that I did use my 1 grain tablets to take 5.5 grains of the new batch. I pray that answers become clear very soon for peace of mind and the well being of all of us.

    September 2019

    Free T3 – 4.2 (2.2 – 3.9)
    Free T4 – 1.2 (.6 – 1.6)
    TSH – <0.01
    Reverse T3 (pending)

    June 2019

    Free T3 – 4.4 (2.2 – 3.9)
    Free T4 – 1.3 (.6 – 1.6)
    TSH – <0.01
    Reverse T3 – 9 (10-24)

    Reply
  4. Karen

    Well I am done being afraid of reporting this to the FDA.I called this morning and filed a report because this has done something really bad to my body.They are getting reports on np and are taking this very seriously because of the symptoms we are having.please file a report if this has made you sick. Something is very wrong with this medication . This is my life and many others that Don’t know how this could cause long term health issues.The side effects are still with me two weeks after stopping np.

    Reply
    • Sharon

      I live in Pittsburgh, PA. I went to Walmart last week to pick up my 90 day supply of NP (120mg and 15mg), and asked the pharmacist if I could smell and look at them before purchasing. I took my old NP tablets with me to compare. The new NP smelled like cat urine, very pungent and they didn’t look the same as the old ones I had with me. The pharmacist even smelled them and said they were different. He thanked me for letting him know and suggested I try and find ones like the old NP by calling other pharmacies to see if they would let me smell and check them before buying. I too like everyone else here have been through the whole debacle of changing tablets through the years and am sick of it. I read about thyrogold on your website and emailed Tammy Lowe who was very kind in letting me know how to switch and how much to take. Janie I thank you from the bottom of my heart for all you do for us. I wouldn’t have known about this if not for you. I am going to try the new supplement and begin to take my health into my own hands for once in my life as I have had enough of the way we are treated by pharma and doctors who don’t care! I feel empowered to be trying the thyro gold so I don’t need to keep relying on doctors as much and drug companies that would put your life in danger for a profit. I really hope it works, if not, I’ll never stop trying till I get there. Janie you are amazing!!!!! Thank you!

      Reply
    • Alex

      Karen, it was not a good idea to call FDA. You should have read the comments from Janie regarding FDA from September. 13 und September. 20. I unterstand it’s about our health. But what do you think FDA will do? They shut down the Acella’s production of NDT for ever. If each of us calls and writes Acella then I’m sure Acella would take a closer look on what happened to their NDT. A compliant to the FDA maybe take the last chance for Acella to correct its mistakes.

      Reply
  5. Karen H.

    Has anyone had their stinky, speckled NP analyzed to see if there is less T3 and/or T4 than the required amount? Or if there is some sort of contaminant in the product? It would seem that starting there would at least give us some necessary information. You would think Acella would be doing this to get to the bottom of the problem and I know that several people on this site have said they sent their defective pills back to Acella. How much time do they need to get us all an answer?

    Reply
    • Dawn

      Karen,
      I brought the tainted pills to a compounding pharmacy. The pharmacist told me the only way to get a true answer is to use a machine that breaks down the pill, but it costs 5 million dollars. He wasn’t kidding when he said this. Other than that, he stated there was no way to measure what was in the pills. Maybe someone else has a different answer. It was defeating to hear this, at the least.

      Reply
      • Dee

        I heated 5 separate tablets, held with pincers over a gas flame. Here is what I observed, using a geologist’s hand lens: The tablet immediately develops shiny bubbles; the speckles are the first to burn; the cat litter smell intensifies until the center of the tablet is reached. There seems to be a definite coating, because when heated a little and broken open, the tablets show a white-ish outer shell, and the inside is like wet beach sand or brown sugar. Very shiny, although I don’t see crystals.
        When powdered and not heated, I observed a few strange fibers, like tiny threads.
        Anyone have a microscope? We have a local university with a chemistry lab. Maybe it can be further evaluated.

        Reply
  6. Jennifer Steinert

    I’m having the same issues as all of you. Had been taking Naturethroid and just switched yesterday to NP Thyroid after I noticed all my hypo symptoms returning.. Had the worst night I can remember in a long time last night….stomach pain, migraines, cold sweats, etc. I guess I’ll go back to Nature throid for now until I can come up with a better solution. My question is, have these NDTs ALWAYS used calcium as a filler? I noticed recently on the bottle of Naturethroid that one of the ingredients in calcium. However they state this on their website: “Calcium supplements, iron products, or antacids must be taken four hours apart.” Does this make sense?!?

    Reply
    • Janie Bowthorpe

      It doesn’t. And Naturethroid went south, too. 🙁

      Reply
      • Lynn

        Janie,
        Is it strange that we have a wide variety of symptoms due to NP? Is it because the pill is useless or it has something nasty in it that we are reacting to? I developed fatigue, joint pain and muscle burning, tinnitus, brain fog and hair loss after beginning Naturethroid and after starting NP the hair loss stopped but everything has gotten worse. Maybe I had a good batch of NP and then a bad batch?But other people have migraines, stomach pains, etc. Should we all have the same symptoms? How long should it take for the symptoms to get better if we find something else that works? It is scary to try something new that could go south too.

        Reply
  7. Nicole

    Was on NT for several years and doing great until I started feeling lousy end of last year and had the labs to show it. Then I switched to NP this Spring and started feeling great again (with the labs improving also). For the last month I’ve been feeling lousy (like I have narcolepsy), and labs have gone downhill. So my plan is to try Synthroid and liothyronine together. After asking several friends, those that are on Synthroid seem to be doing well and have been for many years (even one who has no thyroid due to cancer). I am concerned about synthetic because when on Levoxyl many years ago my Reverse T3 was near 300 and had to bring it down with 20 mcg daily T3 (although Free T3 showed over the acceptable range). I guess I had conversion problems due to 1 MTHFR mutation from 1 parent. It’s been such a roller coaster. So sad we have to deal with all these inconsistencies and zero accountability from pharma! They will learn by losing our business and profits!

    I am also following the advice of no gluten and 200 mcg selenium (via 2 brazil nuts a day). She recommends no dairy too but baby steps here…and the more I cut out sugar and minimize caffeine the better I feel (probably from adrenals). I should probably also start taking magnesium again but I’ve been sleeping so much I didn’t think I needed it!

    Reply
    • Janie Bowthorpe

      Yes, you should be concerned about being on just T4. There are simply too many life issues which can cause problems with the conversion, as well as push high RT3.

      Reply
  8. Rachel Smith

    Hello Everyone,
    I cannot tolerate the latest batch of NP thyroid. Just one tablet caused me to have weird reactions. Blurred vision, headaches, and more. So I am trying Raw Thyroid, by Source Naturals, which is a very clean bovine product.

    On the label it says
    Raw tissue concentrates are made from toxin-free lyophilized glands from animals grazed on rangelands known to be free of pesticides, growth hormones, antibiotics, or chemical additives. This natural product is made without sugar, starch, preservatives, or artificial colors or flavorings, or genetically modified organisms. It contains no yeast, no soy, no milk derivatives, no wheat, and is gluten free.

    It also says it is a synergistic complex made of thyroid tissue, adrenal tissue, pituitary tissue, sinus tissue, spleen tissue, maltodextrin. (from tapioca), American ginseng.
    Other ingredients: Capsule (gelatin) magnesium stearate (vegetable source), kelp, and flogard.

    I realize that it is bovine, instead of porcine, however, a more synergistic approach, seems to work for me better in other areas. Has anyone else tried Raw Thyroid? I had thyroid cancer 9 years ago, with no thyroid left, I am having to take a lot to make up the difference, but I would with any OTC supplement. Right now I am taking 8 capsules a day, which seems like an awful lot, but I’m not sure if that’s just trying to make up for the fact that my numbers were so out of whack. Even on my previous bottle of NP thyroid, which I purchased in June, it was like there was something wrong with that bottle too. I was struggling to take the right amounts and my numbers have really been messed up. I’ve only been taking this for just over a week. So I really can’t say how well it’s working, except I do feel better. I am going to be checking my lab work in two weeks and see how my numbers look. I didn’t see this in any of the possibilities under the over-the-counter list. I went through that list and didn’t feel any more comfortable with anything I saw there. The pharmaceutical types of thyroid replacement are not an option at all. I’m Allergic to the 21st Century, so I have to be very careful about even minut amounts of chemicals or additives, that I don’t do well with, but compounding pharmacies are way out of my price range. One of the nutritionists here in Flagstaff, Arizona, said that several of the people he sees highly recommend Raw Thyroid, but he is not certain if they are just supporting a weak thyroid or not.

    Any thoughts?

    Reply
    • Yesi

      Hi,
      I also live in Az. Ive been doing research on compounding pharmacies. I did some price comparisons and talked to pharmacists at each. If my numbers are all out of whack when I get my bloodwork beginning of Oct,I’m going to ask my dr. to prescribe compounded T3/T4 from Skips Pharmacy in Florida . I already get my LDN from them and their price is very reasonable compared to many other compounding pharmacies. Under$ 65, even less depending on dosage, and price only jumps $10 per month. For myself I’m going to ask for a comparable of NP Thyroid 150, and a 60 or 90 day fill.f that’s doable for you.

      Reply
      • housemaid

        Rachel, here are my thoughts about Raw Thyroid: since you have no thyroid, it would be dangerous for you to just take a bunch of that product. It includes things you don’t need/want like spleen, adrenal, pituitary, sinus tissues! I am surprised they allow that to be sold. For one thing the pituitary and sinuses are very close to the brain and with the danger, however slight, of mad cow disease, that is just too close for comfort. You have no idea how much thyroid is in this mix. If you want to try bovine thyroid, consider something like Thyrogold. You shouldn’t have to take 8 capsules of that. You’d have to do a search to find out how much Thyrogold equals the amount of NDT you were taking before. But I really think you ought to stick to pharmaceutical products because without a thyroid, you are in dire need of thyroid meds. Not NP, but maybe Armour or synthetics because it is a matter of life & death for people with no thyroid.

        Reply
        • Janie Bowthorpe

          Housemaid, not all raw thyroid is mixed with other organs. The bottom line is to read the ingredients list carefully.

          Reply
          • housemaid

            Janie, I was talking about the product Raw Thyroid by Source Naturals, capitalized, not “raw thyroid” in general. This product does have all those extra tissues and is the one that Rachel is taking 8 a day of. I am concerned that this is a dangerous thing tor be taking since it is likely to not have enough thyroid activity for someone like Rachel who has no thyroid gland.

          • housemaid

            Janie, I was talking about the product Raw Thyroid by Source Naturals, capitalized, not “raw thyroid” in general. This product does have all those extra tissues and is the one that Rachel is taking 8 a day of. I am concerned that this is a dangerous thing tor her to be taking since it is likely to not have enough thyroid activity for someone like Rachel who has no thyroid gland.

          • Janie Bowthorpe

            Thank u for clarifying. It may not be dangerous but wouldn’t be ideal when it’s not straight thyroid.

        • Rachel Smith

          Hi Housemaid,

          I had stumbled across a site about mad cow disease, not long before I read your post. I did not want to alarm people unnecessarily, so I did not mention it out here, but I know I need to take precautions. You are correct when you say that it is a matter of life and death for people who have no thyroid. I truly do appreciate your concerns. That’s one of the reasons why I’m out here asking questions. Unfortunately, Armour and synthetics are out for me. Synthetic T3 and T4, even at optimal numbers, with everything else okay, had me literally crippled with pain. Even with massive doses of pharmaceutical pain killers, which I now thankfully do not need it all, I was barely able to walk. I spent a of time in a walker or wheelchair. I will not go back to that life. It was not a life. I thought if I included a copy of the email that I just sent to Thyrogold, it would help you to understand the rest.

          Hi Tammy,

          I was on NP Thyroid, by Acella, and cannot take the latest batch. It is not just The Wretched taste, I actually had some bad physical reactions to just one tablet. Evidently, I’m not alone. According to many of the people, who follow the Stop The Thyroid Madness site, there are some issues going on there.

          I am one of those people who are Allergic to the 21st Century! 🙂 I have found that even minoot quantities of materials, that I might be reactive to, can have devastating results. Armour has too many ingredients in it, that would cause reactions. I was on Naturethroid, before I was on NP thyroid, and did poorly when they made changes. So I am, again, looking for an alternative. I am currently taking an over-the-counter supplement called Raw Thyroid by Source Naturals which may be helping, but I have to take a lot of it, because I have no thyroid. I am concerned that all of the extra hormonal tissues it contains, are not something I need in large doses. Another concern is that the label does not say it’s strictly from New Zealand or Australia, which have very high standards of animal husbandry. I am not certain that it ever did, because I don’t have my old label, but I have been reminded about the issues, with those tissues, that are close to the brain in cattle. I saw your statement about the mad cow disease, which is why you get your products strictly from New Zealand, and that helped me think this might be a good option for me. I know it’s rare to contract that, but I seem to be one of those people that get in line when there’s something unusual going on! Most compounding pharmacies are not even trying to get the USP Thyroid powder anymore, because they’re having so much trouble with availability. Even if they do, the cost is extremely prohibitive.

          I have been looking through your site, and I like what I see so far. However, I do have a question. Can you please tell me how the bovine thyroid is harvested? I need to know whether it is Lyophilized or if you use low heat? If you use low heat how much does that affect the product?

          I would also like to know what you would suggest as a replacement level of your product? I was taking 1 1/2 of the 90 mg, or about two and a quarter grams, of the NP Thyroid.

          I cannot tell you how much I appreciate all of the information that you have on your site, especially in your question and answer section. I look forward to hearing from you!

          Lord Bless You,
          Rachel

          Reply
      • Rachel Smith

        Hi Yesi,

        It sounds like you’re a lot like me, doing a lot of research. I did call Skip’s Pharmacy in Deerfield Beach Florida and spoke with the pharmacist. Andrea. For me to get the synthetic T3 and T4 would only be about $41 a month. But the synthetic T3 and T4 actually had me, literally, crippled with joint pain. I will not go back to that. Unfortunately, to get the natural desiccated thyroid or USP thyroid Powder made up, is far more expensive. She said it cost them $1,000 for a hundred grams. They’re having a hard time finding it, so they’re just not dealing with it anymore. For me 180 mg x 30 days would be 5.4 grams which would be over $100 a month. Which is fairly typical of what I’m finding at compounding pharmacies who actually do use the USP thyroid powder.

        But thank you so much for taking the time to respond. It means a lot to me! 🙂

        Reply
        • Janie Bowthorpe

          Hi Rachel. Be aware that you could have been crippled by the synthetics because you were on too low a dose and not optimal. But hope you find the NDT compounded.

          Reply
          • Rachel Smith

            Hi Janie, I know that is true for most people, however, my numbers actually were optimal. I was on T3 and T4. I was following your site faithfully, and doing all of the at-home testing. I mentioned earlier that I am one of those people who are Allergic to the 21st Century. Some people call it, Multiple Chemical Sensitivities, others call it, Environmental Illness, especially if they are also sensitive to electromagnetic fields, as I am. But I really don’t care for either one of those terms.

            I tell people that I am Allergic to the 21st Century because it makes people smile! 🙂 Which opens a door for understanding. However, I have found that even minoot quantities of the wrong types of chemicals can be devastating for me. Literally, within a day or two, after I switched to the naturally desiccated Naturethroid, the horrifying joint pain went away, and I was able to wean myself off of all of the nasty pharmaceutical pain pills they had me on. I will not go back to that life!

            But I want to thank you again, for your care and your concern, and for the fact that you have this place, for those of us who are having these kinds of challenges, to gather and work them out together!

            You are an amazing woman!

          • Janie Bowthorpe

            Referring to the 21st Century makes sense.

          • Rachel Smith

            Hi Janie, I just wanted to let you know that I am going to be taking Thyrogold. I just got off of a conversation with Tammy and I really like what she’s told me about their product. I will check back in a few weeks and let you know how my world is doing! 🙂

          • Janie Bowthorpe

            Yes, please let me and us know. It’s been around a long time. I especially want to know what amount got your free’s to optimal, if you get there.

        • Yesi

          Hi Rachel,
          So sorry you sufferred so much with joint pain. Some thoughts on the compounded T3/T4; when compounding could that possibly take care of the filler allergy issue? From what I understand Skips only uses 3 ingredients ; T3,T4 and 1 filler of your choice. I also called Woodland Pharmacy in Ca, they do still have access to dessicated thyroid from Canada and Texas; for 135 mg for 30 days would run $80, 60 days $110, 90 days $150, and they said they can ship to Az. For filler they use Microcrystalline cellulose or brown rice flour, lactose or glycerine if any of those work for you. I am hesitant to order dessicated, because of the heat issue here where I live.
          Dessicated is heat sensitive, but Flagstaff is much cooler than Yuma.
          On another note, I too had horrible joint pain for a while. It felt like electric shocks in my hands and feet. I was able to find a dr who listened and was willing to prescribe Low Dose Naltrexone, and that has helped me tremendously, as well as bring my antibodies way, way down. I get mine from Skips in Florida at 4.5 mg.

          Reply
        • DeeCan (I used to be Dee, but someone else is Dee now too)

          Rachel, I’m also allergic to the 21st Century. I’m not really on any ndt right now because the only one I could get was ERFA since I’m in Canada. That went South back in 2015/16. Sorry everyone is having problems in the US with their brands too now, but I’m actually relieved that it is more a widespread problem and I’m not alone. Just extremely hypothyroid and unwell, but not alone. 🙁

          Reply
  9. Vincent Jericho

    For a man of 59 I remain quite athletic. Diagnosed with Graves when 35. Radiated Thyroid. Been a fight since then. Was on Naturethroid…switched to NP about year ago. DOING GREAT!!! Then the stinky pills. Mine smelled and tasted like paint thinner. At first ok but over about 6-weeks crashed. Fortunately I have a reserve of old NP which I am back on and doing well. I called my Pharmacist and at her suggestion filed complaint with FDA. Had I known then what I know now I NEVER would have let them kill my thyroid. For me internet arrived about 5-years too late…

    Reply
  10. Liz Luber

    I, too, have been experiencing regression in various ways since the change in formulation…. I’m wondering – although it’s more expensive, is Armour the equivalent to the old formulation that we all loved and felt good on? Money aside, is it as simple as switching to the Armour brand to achieve the positive results we’d been having on the old formulation of NP Thyroid?
    I’d truly be grateful for thoughts on this – I’m struggling to accept the fact that my symptoms are returning…

    Reply
    • Janie Bowthorpe

      All the NDTs changed from the good products they used to be.

      Reply
      • Dee

        I spoke to 3 pharmacists yesterday, and also a relative who does drug testing for a large pharm. co., about how to break down microcrystalline cellulose. They have no answer. One of the pharmacists actually took out the drug info insert for Armour, and read it for me, where it states the MCC is added to INCREASE absorption! I am going to try mortar and pestle. THis is all heartbreaking.

        Reply
  11. Yesi

    If we decide to go to synthetic T3 T4 , can we and how do we obtain T1 and T2, or do we just have to go without ?

    Reply
  12. Kim

    I was taking Np Thyroid 60 mg tablets 3 times daily and liothyronine 25 mg twice a day.. my dr changed my meds to liothyronine 25 mg 4 times a day and dropped the np and I feel like death way worse then before I ever started medicine.. I just emailed my dr and she changed med to armour 3times a day and liothyronine 3 times a day and I pray this helps me.. At this point I feel like I’m trapped in a 90 year old body!!

    Reply
    • Sarie

      New Labs on NP Thyroid:

      I’ve been on the new NP for 3 weeks now and have been optimal a little over a year. I seemed to be one of few that wasn’t feeling any symptoms returning, etc. I feel best with my T3 slightly over range, and my Naturopath is good with that 💗 Both sets of lab results are on 5.5 grains NP Thyroid, but 2 grains of the old (good) batch, 3.5 grains new. I’m not sure what to do at this point as I feel as I always have being optimal, and so far labs are stable, although they did drop very slightly 🤔 I tanked miserably and immediately back on the new Nature Throid (4 grains) with tanked Frees and a TSH of 80, and was extremely sick. I’m going to recheck labs again in a few weeks.

      I understand that I’m not taking 100% of the new batch. But when I need 5.5 grains, I’m technically only getting 2 grains of the old, good NP. Based on my past and horrible experience with Nature Throid, I would think that only getting 2 grains of the old NP that I would still feel very sick and see symptoms return. And I would think labs would drop much more significantly with taking the 3.5 grains of the new batch that many are not doing well with. I’m monitoring myself very closely. I’m due to pick up my 2 grain prescription soon so I will be fully on the new batches. I did have a full week out of the 3 that I did use my 1 grain tablets to take 5.5 grains of the new batch. I pray that answers become clear very soon for peace of mind and the well being of all of us.

      September 2019

      Free T3 – 4.2 (2.2 – 3.9)
      Free T4 – 1.2 (.6 – 1.6)
      TSH – <0.01
      Reverse T3 (pending)

      June 2019

      Free T3 – 4.4 (2.2 – 3.9)
      Free T4 – 1.3 (.6 – 1.6)
      TSH – <0.01
      Reverse T3 – 9 (10-24)

      Reply
  13. Karishma

    There has been a discontinuation of Thiroyd (By Greater Pharma, Thailand) as told by several pharmacies in Thiland as well as supplier websites. It seems the last batch number is 1500058 with an expiry date of 06 Feb 2022. Anyone has any official word from the Pharmacy?
    Has anyone tried and recommend any other formulation after Thiroyd?
    Thanks.

    Reply
    • housemaid

      Karishma, this is very suspicious that even foreign sources of NDT are drying up at the same time all the US NDT stops working. I have heard of another foreign product called Thyroid S. I have never bought it, but I think it has a lot of fillers. If I hear that Thyroid S is no longer being made, I am going to believe this is a conspiracy!

      Reply
  14. Tabby

    For those of you who’ve decided to not take NP for the time being, what are you doing instead? Janie, what are you using?

    Reply
    • Janie Bowthorpe

      I am still on the former better NP. When I run out, I am playing with different things, like both synthetics (and being optimal) or some NDT supplements like Thyrogold, etc and adding T3 if needed (to be optimal).

      Reply
      • Tabby

        Someone else has mentioned compounding the NDT with as few fillers as possible. How do you feel about that? Also, have you heard of the 15mg pills being affected?

        Reply
        • Janie Bowthorpe

          Try doing a search in this blog post and comments for 15mg. Might show it.

          Not all compounded pharmacies have NDT powder. They will compound the two synthetics. Very few have the powder.

          Reply
          • Russ

            For those of us who may have to go the compounded synthetic route, how do we get optimal?
            By tweaking the ratios of the T3 and T4 until the frees are mid-range and upper mid range? Regardless of TSH ?

          • Janie Bowthorpe

            That’s the problem with compounded….

          • Paula

            Janie, can you please explain why that’s the problem with compounded? I have never heard of tweaking the ratios of T3 & T4 in NDTs or synthetics. How would that be possible? Or by getting two different synthetic prescriptions – one for T3 and another for T4?

            I was thinking of requesting my doctor for a compounded T4/T3 prescription that would be a match to NP Thyroid 1/2 grain so I can multi-dose and increase my dosage gradually according to what my DATS and blood work show.

            Is there a better/different way to get optimal?

        • Dawn

          Tabby,
          I take the 15 mg. and yes, they are affected. I get my medicine through Express Scripts. They sent out my 90 day supply in August with the bad pills. I called them and told them I don’t feel safe taking them, and they sent me a replacement bottle, unfortunately the same. I’m sure it came from the same stock. I believe all doses of NP have been tainted.

          Reply
          • Lynn

            My doctor is aware of the NP problem. She was going to switch me to Naturethroid which is what started this mess for me back in June 2019 (I have since switched doctors because my previous doctor gave me a hassle about switching to NP and said the symptoms must be due to low estrogen and not Naturethroid going bad). My new doctor has been wonderful and is now going to prescribe a compound t3/t4 but I didn’t think to ask if it would be made with NDT powder. I guess I will find out tomorrow from my pharmacist. I think someone mentioned this before that maybe the NDT powder is the problem since Naturethroid went bad and now NP. Although I don’t remember the Naturethroid smelling bad. A friend’s doctor told her she thinks that some of the NDT medicines are coming from China on ships and that storage could be an issue resulting in contamination?

            Janie – do we think that Armour is ok?

          • Janie Bowthorpe

            It was the first that patients complained seeing their hypothyroidism come back. And there were definite visible changes to the tablet as well.

            The problem with saying it’s working is that many patients feel good before they are optimal. And they don’t realize that’s going to backfire. So we don’t know yet. We just know that it changed enough that so many patients left it.

          • Kristie

            Acella called me back tonight, basically just taking a med report on my adverse reaction to the NP thyroid. I told him the pharmacist reported it as well. They said that Acella is concerned about their customers and plans to make this right. Oooookay… will see 🤷🏻‍♀️

  15. Erin Erickson

    I switched to NP after the Naturethroid shortages and I did great. I often felt hyper on Naturethroid and I felt pretty dang good on NP and no more hair fall. My labs from six months ago looked good, my free t3 & 4 were at an optimal level. My tsh is always very low (my Doctor seems to focus more on that). I used to take NP 120 with 2 15 mg. I changed to 30 mg (take 5)..then I got the smelly batch and at first thought my allergies were the cause of the bad taste. Now I’m feeling hyper and anxious and can’t sleep. For the last couple of days, I’ve been taking four instead of the 5 30 mg NP and feel a little better (and less like a hummingbird on speed). I had labs drawn last Friday and have a Dr appointment on Wednesday..I know they’re not going to look good. I talked to a pharmacist and she suggested I wait for my labs before changing meds. The pharmacist said that she is on Armour (though not entirely happy with it) and she never liked NP. My Doctor is not totally on the NDT bandwagon, and I’m afraid he will want me to take synthetic. I don’t know what to do, what to try. Not sure I can afford Armour. I took Armour about five years ago for a short time and liked it – I remember it lifted my brain fog, an amazing feeling. Just want to feel good again! Best to everyone here in their search..

    Reply
    • Starr D.

      Hi, Erin. That’s interesting you’re having trouble with the 30 mg. NP pill,
      because that’s the ones I may be having trouble with, too–giving me
      hyperthyroid-type symptoms, while still getting a lot of low thyroid ones,
      too. I was using 1 and 1/2 per day of the 30 mg. for about 3 months–
      got a new batch in late July, and they smell OK but may be too strong,
      in some ways. (I also took a 1 Grain NP, in the morning.)

      Had an endo appointment earlier this month, and labs a couple of
      weeks before that. Was doing sort of OK until the night before
      my appointment, when I took my last dose of the 1/2 grains…
      hit me real hard–headache, neck ache where the thyroid would
      be if I had much gland left (but I don’t have much due to RAI
      for Grave’s Disease, years ago), stomach ache, and ear-ache.
      Barely felt good enough for Dr’s appointment the next day–
      blood pressure was OK, but my pulse was 100 and it wouldn’t
      come down until I went off all NP for a couple of days. Doctor
      said maybe the morning pill was OK, but maybe something
      was up with the afternoon ones (the 1/2 grains.) He said to
      keep taking the morning NP pills I still have, and maybe take
      Armour in the afternoon (he wrote a different prescription for this.)
      I’m still using up what I’ve got (found some old 1/4 grain NPs from
      January, which aren’t expired.) And frankly, it’s a mess, because
      now that I’ve had that bad episode a couple of weeks ago, I seem
      extra sensitive to this medicine in general, now, and I know it’ll be
      that way for awhile, because I’ve been through this before with
      other thyroid drugs. My labs looked OK according to the Doctor,
      and he felt there was no reason I should’ve gotten the symptoms
      I did…well, it’s either my own weird system acting up in general to
      thyroid medicine, or the NP pills themselves causing trouble.
      But I’ve quit taking the 1/2 grains, just in case they’re the problem.
      And for now, I’ve had to reduce my dose as I figure out what I can handle.

      I hope I won’t have to go back on synthetic drugs as I haven’t done
      well with them for years, but it’s an option I may have to revisit.
      The doctor is willing to work with me on whatever way I need to go.

      Janie, thanks so much for this site! The ability to compare notes with
      others, and all the info you provide, is just so useful and important!

      Reply
  16. housemaid

    Some people seem to be under the impression that the FDA is their friend. No, the FDA is the friend of Big Pharma only. You may be unaware that common blood pressure drugs ending in “-sartan” have been found to be tainted with a carcinogenic substance called NDMA. There have been multiple recalls of various batches of these drugs over the last year. However, most pharmacies don’t really keep track of what batch numbers they dispense when it comes to these high volume drugs, so many people with bad batches are not being notified. And the truth is that the FDA is allowing a certain amount of carcinogen in all these “-sartan” blood pressure drugs, so a person thinks their batch is OK when it really isn’t. https://www.peoplespharmacy.com/articles/popular-heartburn-drug-zantac-ranitidine-tainted-with-a-carcinogen

    The online pharmacy mentioned in the above article (called Valisure) tests every batch of drugs they sell for impurities. Valisure has found this same NDMA carcinogen in Zantac as high as 3 million ng. FDA says this is fine. I’ve never heard of this pharmacy before, so I don’t know if they sell NDT or if just anyone with a prescription could send it in to Valisure. But I looked at their website and they have a page where people can send in information about bad batches of drugs they have gotten. Maybe they would be interested in testing some of these bad NP pills. From what I have read on here, I fear these new NP thyroid pills are not just ineffective but possibly dangerous. They seem to be causing some toxic like effects such as burning when swallowing and nausea. Acella’s website says there are just minor variations in appearance, taste, and smell of NP thyroid and claim they test every batch, but I don’t feel reassured. Here is the webpage for the Valisure Pharmacy where they ask people to report a bad batch experience: https://www.valisure.com/report-bad-meds/ I assume that the bad drug did not have to come from their pharmacy, but not sure about this.

    Reply
    • Karen

      I went to that site and filled out the contact info for np thyroid. I will see if they can test this I don’t know.i have sent pills back to accella to be checked but am not hopeful.But this stuff has burnt my stomach so bad I am in horrible pain.

      Reply
  17. Ana

    I was just looking at Acella’s site and noticed that they have a job opening for a “Quality Control Manager”. The opening was posted on August 23, 2019. This makes me wonder if they fired the last one over the NP Thyroid debacle. That’s the first indication I’ve seen that they know there was a serious problem and that they’re working to resolve it. The position still seems to be open.

    And thank you, Janie, for creating this invaluable resource. STTM helped me to get optimal treatment over the years and during these past few months has been the best forum for patients to share their experiences, insights and strategies for dealing with the NP Thyroid problems. Thanks so much!

    Reply
  18. Anne

    Forget my hopeful comment below about how we have to specify Acella as manufacturer and make sure we don’t get AvKare as manufacturer. I just got back from Walgreens and they showed me it was Acella and they are the new pills.

    Reply
  19. Sabrina Schön

    Let’s trust demonstrable facts, not rumors.

    And remember this was/is an excellent product for so many of us.

    So if Acella seriously tries to clarify this, then we should have some patience to get our good product back.

    In the meantime it will be difficult for many to find an alternative.

    Some of us changed already, like I did, because I had no choice – well knowing, with all the realistic fears and facing the facts, reading all the helpful things here on STTM (thank you so much Janie).

    And what can you say after taking a new medication not even a full week? Nothing.
    And in 2 weeks? Not so much more.
    May be in 6 weeks.

    Maybe Acella has solved the problem by then.

    May be, may be, may be.

    ACELLA !! WE ARE WAITING FOR FACTS !!

    Reply
    • Anne

      Sabrina, can you share with us what you are using instead and whether it is good?

      Reply
      • Sabrina Schön

        Anne, yes, in about 5 weeks I’ll be able to tell you my experience.

        Reply
        • Lynn

          Can you tell us what you are using now and then let us know in 5 weeks if it helped?

          Reply
          • Sabrina Schön

            For the moment I try synthetic T4 and a little amount of compounding pharmacy (T3) with that.

            If that works I’ll carry on with this, if not, I will change again.
            (And, like Janie says, trying to stay optimal)

            I’m living in Europe.

  20. Terry

    I received a text from Walgreen’s that my script for NP Thyroid is ready for pickup. I called and the batch is on the bad list. Do I ask for a different refill? And if so, what do I ask for? I know I’m not feeling the greatest but thought it was the gut/mold issue I’ve been trying to resolve.

    Reply
    • Dee

      The pharmacist at my local Walgreens just told me today that Acella is not shipping anymore
      NP Thyroid to them. Is this nationwide?

      Reply
      • Terry

        That’s interesting. I wonder if my Walgreen’s might get a call from them not to dispense the NP Thyroid.

        Reply
  21. Karen

    Ok new labs drawn on September 13 after increased dose of np. Tsh 45.43 ft4 .5 ft3 not in yet.That is on two grains numbers are alot higher on increased dose. Not to mention horrible side effects on np.i am going to say something is wrong with all porcine powder because I did bad on compounded also.so I am going to try tirosint sol to see if I do better. Just to add my tsh on September 10 was 0.84 my Dr said something is really wrong here and wanted rechecked big fluctuations here.Hope this helps people that are not doing well on np.

    Reply
  22. Melissa

    I just received an email from Express Scripts that they are unable to fill my script for NP Thyroid!! What do I do??? I cannot take Synthroid and Cytomel, I tried that once and a lost two weeks of my life, I was in such a fog and had such horrible headaches.

    Reply
  23. Yesi

    I recived a call today from David at Accella. He promised to send new 120s and 30s to my pharmacy to replace the bad batch I have now. He said someone else would call me tommorow and that I would get package in mail to send back bad batch. It sounds like everyone else’s experience, so we will see if they follow through, and investigate as promised. Any one been on compounded T3/T4, with good results?

    Reply
    • Dee

      Steven promised to send the same here, and nothing happened.

      Reply
      • Amy Lynn

        Same story here! Multiple phone calls to Dave at Acella and a 25+minute conversation with that Steve guy in Massachusetts almost 2 weeks ago telling him everything, and I’ve got nothing…no replacement pills nor envelope to send them back. Just going to take the pills I have & hope for the best, that they got enough complaints now to fully look into it/change it back! Tried Armour as a replacement, and that was a $60 disaster. Tirosint (the best T4) out of reach for me right now monthly cost-wise

        Reply
        • Anne

          what happened with Armour?? Did it not work for you?

          Reply
          • Amy Lynn

            Anne yes, Armour did not work for me. Felt so tired/sick the one day I managed to take it. I’m on a decent dose too (3 1/2 grains.) Not only that, but I believe I also had an allergic reaction to something in the fillers, maybe? My face immediately swelled up, then my face/neck/chest got all red an hour after taking. After that a few hours later, my skin started itching all over. Not fun! I’m only allergic to sulfa drugs, that I know of. My mom and my sister take Armour seemingly without issue, but it’s not for me & my body apparently!

  24. Valency

    An update: I picked up my newest bottle and I now have the speckled pills (which smell like a littler box and taste horribel!) mixed in with the whiter, non-odorous, harder pills. I spoke with people at Acella and they are sending me an envelope to send back samples for the FDA. Let’s keep sharing as much info as we have.

    Reply
  25. Catherine

    Hi. Did anyone actually receive the return envelope in the mail to mail in the replacement medication from Acella?

    I never did. And that was after many calls to Acella and filing a report with the pharmacist at Acella. They told me they would ship replacement pills to my pharmacy and mail me replacement pills to my pharmacy. My pharmacist also spoke with them.

    I have received nothing promised and this happened back in June with the 90 MG pills of NP thyroid. At the time, I thought it was just a bad batch but now I see it was far more than that.

    After that incident I would not touch the 90 mg pills. I had my doctor order all 30 mg pills and so I took 5 a day. The experience on 90 mg pills was too severe. Looking back I should of stopped taking NP then.

    I am allergic to Armour and so I moved to expensive compounded porcine/NDT powder compounded with Gycine last week. This is my last shot at NDT as I wont touch Naturethroid with all the bad reviews or WP as it is too new after the changes made.

    I had half my thyroid removed due to Papillary cancer. I flare from levels that are off caused new swollen lymph nodes to appear back in June. That is not acceptable for people like us who are struggling.

    Reply
  26. Ginger

    I started calling Acella and left several vmails on the CS line. My last one was less than charming and I stated that I would continue to leave messages until someone called me back so I could place a complaint about tainted medication. I received a callback from a gentleman named Steven, who identified himself as one of Acella’s pharmacists. He took a detailed (but not personally invasive) report from me that took approximately 30 minutes. I advised him of color, smells and taste of the “bad” pills and the symptoms I had. He was very kind. Once we’d finished, he asked if I would be willing to send them the affected meds for analyzing. I have a new script en route from my pharmacy and told him if the new batch is also bad, I’ll reach back out and we’ll discuss me sending them some. I asked him what Acella planned to do about this as I had read multiple reports similar to mine. He said that Acella is “aware of the reports of issues with NP Thyroid on social media” and have put up a notice about that on their website but they are standing firm that nothing has changed in the manufacturing or ingredients of NP Thyroid. Okey dokey. I hung with him and followed Acella’s posted instructions to contact the FDA to place a complaint about tainted medications. Just waiting for the paperwork to come.
    I have about a month of good meds left, then I don’t know what I’ll do.

    Be well everyone,
    Ginger

    Reply
    • Janie Bowthorpe

      They “stand firm” that nothing has changed yet patients are experiencing horrible symptoms…another example of gaslighting.

      Reply
      • Ginger

        I particularly enjoyed the part about “they are aware of social media.” Well, that’s a load off my mind. We’ll all just go back to being sick as hell, you guys just keep up with your web-surfing. It never changes, does it?

        Reply
      • Dee

        Janie, I don’t think any of us should have mentioned the size, color, or smell; unfortunately, that is what they
        hung on to. My second call to Steven only emphasized the horrible allergic reactions I am having.

        Reply
        • Janie Bowthorpe

          Yes they have hung onto those three. But they also knew/read/heard about the reports of worsening hypo from many of you!

          Reply
          • Janie Bowthorpe

            And I should have added: the fact that the changed tablets smell worse than ANY NDT has ever smelled in the last 17 years, plus the patient descriptions of a horrible taste to the point of making some nauseated…underscores that many things are quite wrong on top of the massive amount of patient-described symptoms of a return of hypothyroidism in terrible ways.

          • Ginger

            A little update from me- I called Express Scripts (as previously stated) and told them what had happened. The pharmacists sent me a replacement bottle of each of the 2 dosages I take. They were both the same foul smelling bad ones. I now have 4 huge bottles of stuff I can’t take. Taking what little of the good pills I have. My dr called in a script for Armour I haven’t started yet (hey now, that’s expensive) and I’m just waiting to see what happens with Acella.

  27. Tracey

    Hi Guys,

    I recently changed to tirosint + cytomel after being forced to leave Nature Throid and now NP. I am starting to hear more and more that Tirosint has also changed manufacturers – and is no longer working for people. Has anyone had this experience with Tirosint no longer working for them? Any info on this is appreciated. Thank you!

    Reply
  28. Yesi

    I’m thinking of asking my dr to prescribe a compounded t3/t4 , comparable to the dosage of NP Thyroid I was on. Has anyone done this? Any suggestions on reputable compounding pharmacies? What type of accreditation to look for? I dont have a compounding pharmacy anywhere close to me, going to have to find one willing to mail.

    Reply
    • Lynn

      I talked to my pharmacist today and the odd thing is that when smelling the new NP thyroid (which I think is horrendous) vs. the old NP – my husband son and the two male pharmacist’s think the new one smells better than the old and my daughter and I think the reverse. They are willing to compound a t3/t4 for me. Maybe that is the way to go?

      Reply
  29. Lynn

    Another question – do we think that NP is basically a sugar pill or a pill with something that doesn’t agree with our bodies? Wondering if I am better off being hypo than with the burning, aching, ringing and extreme fatigue.

    Reply
  30. Anne

    Have you guys seen this? GoodRX NP thyroid images?
    https://www.goodrx.com/np-thyroid/images
    They say this one manufactured by Acella loks like this
    and this one manufactured by AvKare looks like this
    And they are clearly different. The one that I have that I am scared to use looks like the one manufactured by AvKAre
    Are they a generic version? It looks like we should just ask for the ones made by Acella.

    Reply
    • Anne

      Just adding to this…I called Walgreens to tell them I only want my prescription from Acella not any other company and they just emailed me to tell me it is out of stock so it is delayed. So clearly these batches are not from Acella.

      Reply
      • Anne

        and also there seem sto be other manufacturers of NP according to this
        https://www.findacode.com/ndc/drugs/NP_THYROID_60
        NDC Trade Name Labeler Name
        42192-0330 NP Thyroid 60 Acella Pharmaceuticals, LLC
        42291-0643 NP Thyroid 60 AvKARE, Inc.
        71335-0414 NP Thyroid 60 Bryant Ranch Prepack
        45865-0566 NP Thyroid 60 medsource pharmaceuticals
        51655-0132 NP THYROID 60 Northwind Pharmaceuticals, LLC
        68788-7032 NP Thyroid 60 Preferred Pharmaceuticals Inc.
        53002-1029 NP Thyroid 60 RPK Pharmaceuticals, Inc.

        Reply
    • Yesi

      I called my pharmacy and, they confirmed that my speckled, grey, stinky pills were indeed from Accella.

      Reply
  31. Hadassah

    Now that NP Thyroid is not working well . What is everyone that was dosing with NP switching to ? My pharmacist said he can not get NatureThroid . Armour is prohibitive .

    Reply
    • Rita

      I went back to Naturethroid a couple of weeks ago. I am chewing up the pills before swallowing and will get tested in 6 weeks. So far I feel ok, more energy but still some hair loss. But I have read that the hair loss won’t instantly get fixed. I am also sleeping great and no anxiety. Maybe the key to taking Naturethroid is chewing it up? Supposedly works with Armour…

      Reply
      • Michelle Sarchiapone

        I had a old 3 month supply of WP thyroid I switched to. When I run out, if the NP mystery has not been solved, I will try a compounded med.

        Reply
  32. Melanee Ables

    I’ve been on NP for several years and have always been happy with it. I was underdosed but happy overall. 🙂 I also noticed the last prescription had a foul smell and taste. So much so that I double checked the pills and felt concerned taking them. I’m on 120 mg/day. My pharmacy only carries the 30 mg pills so I take 4 . Even on that high-ish dose my labs were not optimal so my dr added Synthroid (name brand only). I think that is why I am doing well even with the change of NP. Optimal FT3 and FT4 for the first time ever.. and I’ve been on meds since 2012. All of that is to say.. sometimes synthetic is okay! I’m a huge on natural products but even my dr said some of his patients aren’t doing well on NDT alone and thrive once he adds Synthroid.

    Reply
    • Yesi

      Melanee,
      What dosage of synthroid did he prescribe?
      120 NP Thyroid + how much Synthroid?
      I’m also on 120 NP.

      Reply
      • Melanee Ables

        sorry I just saw this! I am on 50 mcg Synthroid T, Th, Sat, and Sunday and 100 mcg on MWF. I just received my first labs back after this change and I am finally in optimal ranges.

        Reply
  33. Debbie M

    I was originally on nature troid and doing well. I switched to np thyroid due to weird test results and shortage. Was on it for 4 months but too much hair coming out so decided to switch back to nature troid. Picked script up from pharmacy and checked pills when I got home they were darker with specks. Just like your description of NP thyroid. I had some left over nature troid pills from previous script and they were white with no specks. This is so frustrating! Don’t know if I should take them or take back and show pharmacy.

    Reply
    • Janie Bowthorpe

      You were clearly underdosing yourself on the former good NP. It’s an excellent product if one gets optimal on it. Optimal puts the free T3 at the top area of the range with a midrange FT4. Both.

      But if one gets the changed NP, and even the changed Naturethroid, there are consistent problems, sadly.

      Reply
      • Deanna

        I am on NP Thyroid and have been for about 2 years. But in the last few months I have had the following problems: Extremely itchy skin, red rash, profoundly tired, head aches, heavy chest and heart palpitations off and on.
        My lab results are: TSH: .82 (.40 – 4.50 mlU/L) Free T3: 4.1 (2.3 – 4.2 pg/ml) Free T4: 0.8 (0.8 – 1.8 ng/dL)
        The NP I have at this time does not have the spots on them and not a strong smell.

        Reply
        • Deanna

          To further explain my last post: I am on 120 milligrams of NP Thyroid. My endocrinologist now says, “see this is why I do not like to prescribe NDT as it is not standardized and I worry about your heart and bones”. She will prescribe NDT but is nervous about it. It is my understanding from what I read here and other places is that NDT is standardized, and is the same amount of T3 and T4 in every pill; is this correct. What does it mean when my TSH is so low and T3 is up so high. Can anyone tell me if they have experience and think that my numbers would be considered optimal. I have felt good on this amount as I said up till a few months ago. Thank you

          Reply
          • Janie Bowthorpe

            NDT has always been like any medication out there–an ALLOWED and low percentage of variation between batches. But that is not changed that we have soared on it.

            And his comment totally ignores that the US Pharmacopeia does have a standard for the thyroid powder.

            As far as your low TSH, THAT.IS.PERFECTLY.NORMAL on NDT or even T3. Doctors stupidly freak out about that, claiming bone loss and heart problems…yet we have constantly seen patients report IMPROVED bone density and IMPROVED heart function because of the direct T3.

            As far as your high FT3, that is where we are SUPPOSED to have it when optimal, along with a midrange FT4. Both. So if your FT3 is high with a low FT4, that is probably pooling of the T3 due to a cortisol problem that needs discovery and treatment. https://stopthethyroidmadness.com/pooling

            And this: https://stopthethyroidmadness.com/optimal

            We HAVE to stand firm against doctors who go by the TSH, who think we will have bone loss or heart problems, who don’t understand that it’s inadequate iron or a cortisol problem that causes issue when raising towards optimal. https://stopthethyroidmadness.com/ndt-doesnt-work-for-me

            Finally EVER SINGLE BRAND of NDT has been ruined. Every single brand. NDT used to work far better, was consistent, didn’t cause problems like it does now. So now we have the fight to be LOUD that we want to know WHAT IS GOING ON.

  34. Debbie M

    I was originally on nature troid and doing well. Switched to np thyroid because of weird test results and shortage. Was on it for about 4 months. Lots of hair coming out so decided to go back to nauture troid. Picked up script yesterday. When I got home looked at pills and they are darker with specks just like the np thyroid you describe. They have no smell though. I had some nature thyroid pills left over from a previous script and compared them to the new ones and they are white with no specks. So frustrated. Scared to use them.

    Reply
  35. Karen

    Ok this gets strange.new labs after six weeks on new doses of 120mg.only have tsh results today. Tsh 0.84 last tsh on July 31 17 lowest I have had for years.does not explain sideffects on these new pills.was taking 105mg with tsh of 17 my stomach is so inflamed I can hardly eat and my skin burns and wierd rashes.these pills do not seem consistent.will wait to see the rest of my lab results.but I have stopped np because I feel so bad even with one 15mg tablet.

    Reply
  36. Sabrina Schön

    In the StopThyroidMadness-facebook is a comment from “Rachel Librach Nisenson”, which says, that David Margolis from Acella told her on the phone, that “..the source of the thyroids are from Europe and North America..”.

    So “from Europe” seems new.

    I’m from Europe and I’m sure, that we have NO producers of desiccated porcine thyroids.

    As far as I know, there are 2 companies in Europe, one in Italy, the other in Spain, that are buying desiccated thyroids from South America, testing them and sell them again.

    Additives in desiccated thyroid like lactose, salt, sugar (and may be more?) are allowed according to USP – without need to be listed.

    So may be this change in source changes a lot?

    Reply
  37. Jennifer

    Someone asked if Armour had changed their lower strength tablets back to their old formula. I was hopeful so I called and asked Allergan (Forest Pharmaceuticals) and they said no, that all of their strengths still have the MCC. …Which leads me to wonder why manufacturers of NDT even put microcrystalline cellulose in their tablets when so many of us can’t take them after that. Does this cheap filler save them so much money that they can afford to lose hundreds of customers? I also looked up Avicel which is the trade name for this cheap wood pulp filler that is added to some drugs, supplements, and foods. What I found is that Avicel is usually imported from China and may contain Propylene Glycol, Talc,Wood Pulp, Grass, Newspaper, Lead, White food dye, Calcium and other “binders, undisclosed”. That makes it hard for me to believe that these companies are very concerned about putting out a bad pill. Is it all about the money?

    Reply
    • Starr D.

      I never understand why some companies are OK with cutting corners on ingredients, etc, when they’re making
      at least some patients sick in the process. I’ve had this talk many times with different thyroid drug companies,
      when they’ve changed their formulations (usually changing the “inactive” ingredients, which can affect how you use
      and absorb the pills.) I told one guy at Synthroid a long time ago, “Look, I’d gladly pay for the older, better version
      made before 1982-83, if I could be well again,” He said, “Well, unfortunately, most patients don’t feel that way.”
      He made it sound like their company just felt it was better to be cheap than to put out a better product. And that’s
      the way it seems a LOT of these thyroid drug companies operate. And the Food & Drug Administration basically
      has let them get away with it. I can’t say what the new FDA head would say about any of this, though, as I’ve not
      tried to contact them (yet) about any of this–though I might in the future, even about why in general they don’t
      make sure we have really good, reliable thyroid drugs we can count on, whether they’re natural or synthetic.
      In the past, higher-ups in the Endocrine dept. at the FDA have made it sound to me like they have “no power”
      to do anything to correct problem thyroid drugs that are causing some patients harm. That’s wrong. If I feel
      better soon (as I’m currently having problems with NP–not sure if it’s my dose or their medicine), I may look
      into contacting the FDA again about the safety of ALL our thyroid drugs, especially when they are changed in
      in some way. P.S. I also got extra-sick years ago when Levoxyl added microcrystalline cellulose and
      croscarmellose sodium to their their ingredients instead of some things like potato starch and lactose,
      and when Armour added microcrystalline cellulose instead of some more simple, basic “inactive” ingredient
      to its pills. It shouldn’t have to be this hard to be a thyroid patient, who’s just trying to have some decent health!

      Reply
    • Amy Lynn

      Wouldn’t surprise me honestly if they used bottom of the barrel fillers! Just tried Armour for the first time ever yesterday (it was $60 for the same 2 dosages that I’m on with NP, only a month’s supply, and that’s with with insurance) and within an hour I broke out in a red, sunburn-like rash on my face, neck, & chest. Also my skin started to itch everywhere. My mom and my sister take it with no problems, they say. Hmm. No more Armour for me though, can’t take it!

      Reply
  38. Leslie

    At the end of August with a threat of a hurricane looming over my state, I was frantically calling my pharmacy to see if the batch of my thyroid np was bad. It tasted and smelled like mold! I felt vindicated hearing the pharmacist gag over the phone after smelling the bottles. He put in a new order and encouraged me to contact the company to which I did. I left a voicemail and still have not heard from anyone.

    I have picked up a new prescription and to only have the same problem again! I wish I had seen this update before calling the pharmacist :/

    Reply
  39. Lynn

    I read the above suggestion about someone making the changed Armour work by crushing them. I just chewed up my “new” NP. How would crushing it or chewing it help it to work better? Thanks!

    Reply
  40. Angela Schuster

    I recently picked up a refill of my NP Thyroid and immediately noticed a difference in the “taste” of the tablet, almost chemical like? I even went back to look at the RX Bottle to make sure I did t accidentally take a different RX I keep in the same cabinet but use occasionally. I confirm that I did not do this and that I was taking the NP thyroid pills. I thought it seemed odd but haven’t noticed many changes if any to how I feel physically. I’m concerned though, after reading this post and seeing the comments from others in the group. I was having a hard time getting nature through aid due to shortages so switch to NP about a year ago. I go in for labs next week so I’ll be curious to see if anything has changed in the 3 or so weeks I will have been on this seemingly new formulation.

    Reply
  41. Jean

    I am very suspicious as to why every company making the pills are all changing them. It is not s common practice to change medication way back. Today, however, these pills have changed numerous times! Now every company makes a bad pill. Are the people working at making the pills aware? I would like to know what is really behind all of this. I know big pharma got Trump to change the absorption product. I think big pharma is behind all of this. Are all 4 companies ignorant to something? I’m sure they wouldn’t want to sell a bad product.

    Reply
  42. Pat Boatman

    Why am I not able to ask questions on your Facebook page? I am getting pretty desperatefir some help since I have a idiot dr

    Reply
  43. Sabrina Schön

    What do you think about getting the drugs testet by an independent laboratory?

    Reply
    • Janie Bowthorpe

      It’s being explored.

      Reply
      • Jeanne

        What about Valisure? They test every generic for contamination before filling a prescription! Your doc can order a prescription from them via EMR too. I am considering using them before my next NP Thyroid refill….

        Reply
  44. Paige

    The way you described is not what I just received my NP. It tastes like candy! So I assumed my package was older version. So what are you guys are going to do about it? If they companies won’t listen to us? How we can survive it? Most of us won’t go on chemical medication like Levo or synthryoid.

    Reply
    • Janie Bowthorpe

      It can actually be workable to be on synthetic T4 with synthetic T3 and getting optimal. Optimal puts the free T4 mid-range and the free T3 at the top of the range.

      Reply
      • Paula

        I have terrible side effects (mostly pain) with synthetics (T3 and T4) so that is not an option for me. Any other suggestions at this time?

        Reply
        • Janie Bowthorpe

          Paula, that can mean you weren’t optimal at all. Study this page: https://stopthethyroidmadness.com/optimal

          Reply
          • Rachel Smith

            Hi Paula, just so you know, I also had extreme pain when I was taking the synthetic medications. I have problems with just about every synthetic medication that I have tried. I believe that the fillers they use in the synthetic T4 and T3 caused inflammatory problems for me. My numbers were at optimal, but the joint pain was, literally, crippling. When I switched to Naturethroid years ago, that horrifying crippling joint pain was gone. I did very well on that until all of the problems with nature throid and I switched to NP thyroid and I did very well on that until recently. Now I’m looking at getting a over-the-counter supplement because I don’t know how else to make this work.

            Janie, I hope the Lord blesses you in extraordinary ways for continuing to maintain this site and help all of us get through these challenging times! Thank you!

          • Janie Bowthorpe

            Your last comment is very kind, Rachel. Thank u. I could use any blessing I can get.

      • Anne

        what abot the other Ts and Calcitonin which helps prevent osteoperosis?

        Reply
        • Janie Bowthorpe

          Well, we can hope conversion to them will happen. And there are ways to buy just T2, I’ve noticed. But we have no experiences with it in order to guide.

          Reply
    • AP

      I have the same experience… lightly sweet and I had to dose down from the same amount I was taking of thailand thiroyd because the acella is stronger to me. I live very rural and most people are on synthetic. I wonder if my pharmacy just doesn’t go through the pills as fast. Who else is rural vs city and having good vs bad experiences?

      Reply
  45. Karen

    I just got off the phone with my pharmacist.she said this needs to be reported to the FDA. Because if accella does not recall this bad pills.This would push them to address this sooner.The more people who will report the quicker it will be resolved.we cannot sit back in fear about ndt being pulled and allow them to sell this crap and deny anything is changed.

    Reply
  46. Karen

    I just got off the phone with my pharmacist.she said this needs to be reported to the FDA. Because if accella does not recall this bad pills.This would push them to address this sooner.The more people who will report the quicker it will be resolved.we cannot sit back in fear about ndt being pulled and allow them to sell this crap and deny anything is changed.

    Reply
  47. Trudy

    Hi I wrote a few says ago asking if the same thing could be happening with the tablets from Thailand’, I take a product called Thiroyd which has always worked well till my batch last year which produced Tinitus in me but thought maybe it was a coincidence but have just started a new batch and the tinitus is even worse. Also very bad head, had to sleep sitting up last night but can’t be sure it’s from the tablets. Is anyone else having the same experience with these tablets. The armour tablets didn’t suit me at all. Don’t know what to do. I live in Ireland so don’t know where to turn. Many thanks, just reading your blogs makes me feel I am not going mad.

    Reply
    • Valency

      Trudy, after a new endo switched me to Armour in January, I developed severe tinnitus and with a throbbing/pulse in my head. I was finally able to switch back to NP and was doing much better until the last few weeks. They changed something and not the tinnitus is creeping back in, along with the throbbing head — especially bad in the morning when I wake up and take my initial dose. I never had tinnitus before taking Armour. Interesting note about the possible source being Thailand. I’m calling the manufacturer today (Acella) and I’ll see what they say.

      Reply
    • Trudy

      Thanks for confirming what I thought, I would say different tablets have the same base source. Have discovered I have a kidney infection and gastritis so am feeling a little better now on treatment and the tinnitus has eased a little.

      Reply
  48. Dawn

    So now I’m confused. The specked pills are bad with the horrible smell, and now there’s another new pill out there that’s white but has no smell and is just as bad? Thanks for clarification.

    Reply
    • Amy Lynn

      Dawn to answer your question, yes (at least, that was my experience.) The whiter pills that hardly smell (along with the speckled, smelly ones) are no good! Side effects/reactions galore. Again my experience, but maybe in time more people will chime in. Only good ones I’ve taken were the smooth, yellowish-colored ones with the normal ndt smell. I’ve been on NP for over a year now (about when the WP/naturethroid shortage started.)

      Reply
      • Ana

        I also had a very bad reaction to the white, odorless tablets. The symptoms I had (headache, inability to think clearly, difficulty focusing my eyes, stiff muscles, water retention, and a strange feeling in the back of my throat) were exactly what I experienced on synthetic t4/t3. I suspect that AvKARE (a repackager/distributor, not a manufacturer), working on behalf of Acella, subcontracted to a number of manufacturers to produce NP Thyroid. They probably went with the lowest bidders. My guess is that an unscrupulous manufacturer couldn’t obtain enough porcine thyroid powder and substituted synthetic t4 in some batches. I agree that getting the pills analyzed by an independent lab would be a good idea. I do wonder if that type of analysis would be able to determine whether the t4/t3 in the porcine pills was deactivated or not. By the way, there have been some recent problems with synthetic t4 drugs too. Patients have reported that Tirosint is no longer effective.

        Reply
        • Valency

          This is good intel — the pills I’m having the bad reaction to are white, hard, and have no odor at all. I’ve got a call scheduled with Acella this afternoon.

          Reply
  49. Karen

    Janiee she is right about the new pills.I got my new pills four days ago from accella they are light colored and no smell.after Taking them I also got the same symptoms and a few more.i know when I am having an allergic reaction and this was bad.i called and left a message again with David and told him something is definitely different in the pills.here is the lot#M327B193 exp date 1/2021.

    Reply
  50. Amy Lynn

    Important update, and maybe this discovery can help.

    I gave up on Acella ever sending me new pills and decided to go back to my pharmacy yesterday, and boy am I glad I did. Pharmacist on duty was super helpful. I showed her all the pills I had, she listened to all of my concerns (even showed her this post) and she then proceeded to open up 3 new, sealed bottles. She poured them out, and we both took a look. First bottle of 90’s were all smelly/speckled, no surprise there. 2nd bottle of 90’s were mixed; speckled/smelly in with the normal/yellowish smooth ndt-smelling pills. 3rd bottle were the 120’s (I take 2 different doses a day) and this one was the most shocking. 3 different looking pills inside! The yellow, normal ones, the speckled/bad ones, and different white, shiny, non-ndt smelling ones. Seriously they smelled like nothing! Not sure what this all means, but I don’t trust this company now. There’s just too much variation going on between pills in the same bottle. She said she could not in good faith sell the speckled ones, as she thought they smelled compromised/rancid, too. Going to try Armour and/or 2 synthetics until all this gets resolved.

    Reply
    • Janie Bowthorpe

      I want to copy and paste what you said was in one bottle, as that’s VERY strange and concerning:

      3 different looking pills inside! The yellow, normal ones, the speckled/bad ones, and different white, shiny, non-ndt smelling ones. Seriously they smelled like nothing!

      Reply
      • Amy Lynn

        Stop the thyroid madness yup, true story! I took the new white, virtually no smell 90mg NP this afternoon, and I’m not happy to have to report that I’m experiencing dizziness, dry mouth, vision problems (blurry/seeing spots & my pupils are so tiny even in low light it’s weird) flushing & redness on my cheeks/face. Done nothing else different and I take no other meds or substances. Not good!

        Reply
        • Karen

          Do you have the lot# because my replacement pills are light colored and no smell. I also had the same symptoms plus a few more.i knewni was having an allergic reaction.

          Reply
          • Amy Lynn

            Karen yes, I posted them in the lot numbers on Janie’s blog.

    • Karen

      Janie, New Lot #. M33OE193. Tastes horrible, symptoms returned like aching hands and feet fatigue, no patience.

      Walgreens, Monona WI

      Reply
  51. Val

    I cannot tell you how horrified I am to have found that I was correct, and there has been a change to my NP thyroid tablets. I thought I was nuts! The pills are noticeably harder — which no longer makes them ideal sublingually. Unfortunately, the horrible side affect of loud ringing in my ears that I experienced on Armour has now been duplicated with the NP. I’m guessing it is an additive that I am reacting to, something that hardens the tablet. Can we lobby them to change it back to what it was before? It was the only NDT that really worked for me. 🙁

    Reply
  52. Catherine

    Hi. It looks like some are reporting the pharmacy expiration date. I just wanted to comment that the lot and expiry number are on the original Acella bottle from the manufacturer that the pharmacy dispenses from. They usually come in 100 pill bottles. Note: the expiry number is not the one year expiration written by the pharmacy. You would need either the original 100 pill bottle or try to get the pharmacist to look it up. If they have a good computer system and are organized, then they should have that information.

    Reply
    • Hadassah

      I’m on the fence now with my NP refill .I’m due for a refill and my pharmacist told me that he has the 15mg NP it has no smell nor any specs and is all white as usual . That lot # was posted here that it’s not good. Is it possible that some even with the same lot # can be good ? Should I take the risk ????

      Reply
      • Janie Bowthorpe

        We are learning together. And somehow, it does appear that a lot number can be shared with either the former umchanged tablets and the changed tablet. So the best thing to do is go to the pharmacy and look for specks on the tablets. Specks seem to go with the changed tablets that have caused a lot of reported problems.

        P.S. As far as smell, all NDT smells. But the changed tablets, which seem to go along with a serious return of hypo and even worse symptoms (nausea, burning in stomach, to name a few) seems to have a quite pungent smell.

        Reply
  53. Jennifer

    I always get a sealed bottle of 100 NP Thyroid from Walgreens. On 4/26/19, I got a lot# M331A19-2 for 90MG Tablets, expiration date of 12/2020. At first I had some burning on my tongue when I took it sublingually. However, the pills looked and smelled normal. I was finally able to take them without problems. (I would like to note though that Acella now included a Serial#, GPIN#, and a bar code as well as their usual info of Lot# and Expiration Date on the bottle.) I asked Acella about this and they said they were updating their packaging for better tracking.

    I had my script refilled on 7/17/19. This time I got a bottle of 100 that expired on 10/2020 (2 months earlier than the bottle I had previously bought 3 months before). It also had the updated packaging including the Serial#, GPIN#, and bar code. I’m wondering why Acella suddenly updated their tracking abilities right before the horrible pills came out. I’m also wondering why my 12/2020 pills seemed okay and the older 10/2020 pills smell like cat urine and look differently. Does this mean they may have manufactured some decent pills since the bad 10/2020 batches?

    By the way, the best I can read it, it looks like my 10/2020 pills have a Lot# of M331B19-1.

    I complained to Acella 2 or 3 weeks ago. They said they’d get back to me concerning my case# but I haven’t heard anything. I haven’t called Walgreens. Maybe I should.

    Reply
  54. Christine

    Thank you for posting about this. I think that I have been affected. I was taking 60mg NP Thyroid with TSH 1.8 and low upper range FT3 and FT4 and feeling good for about 1 year. Labs and doctor visit in May 2019. Feeling good, continue the course. Refilled my NP Thyroid on 6/4/19 and after about a month I started to feel bad. Thought it was temporary and kept going. Emailed my doctor about 1 month later saying that I was feeling bad (headaches, fatigue, weakness, constipation, irregular periods, depressions, etc) for the past month and would like my thyroid checked. She agreed and my TSH was 4.38…highest I have ever been. I have since changed to Tirosint because I was suspecting that NP Thyroid may be raising my antibodies so this gave me the nudge to try something else. I kept thinking it was something that I was doing wrong but reading your post helped me to realize that perhaps it was out of my control. My pharmacy told me that they do not have the lot number for my batch 🙁

    Reply
  55. Sabrina Schön

    May be another Faktor X #7 ?
    The Producers have to treat the dessicated porcine Thyroids with a sort of desinfection/virucide as they found out, that the (new) sources are contaminated with whatever (african swine pest)??
    And what they say would be right “nothing obvius changed”.
    And it would explain every single reaction the patients report.

    Reply
    • Lisa

      But it shouldn’t change the size of the tablet.

      Reply
      • marny

        Hmmm…. if this were trye, an added chemical I would imagine eould affect clumping, and may have to add something to counteract it, making them dif shape? I wouldn’t put a pesticide past them.

        Reply
  56. Waveeylines

    Oh nooooo! So shocked to discover its now happening to NP!! What is going on? If theyve changed the fillers than thats me cooked as am sensitive. Am in the uk and our pharmacsots dont have the facilities to compound their own. I will not go back on levo and T3 it wasnt great and ndt was miles better. Cant believe its being suggested!!!
    Didnt armour change their lower strength tablets back to their old formula? Or was that a myth? I was fine on armour till they added cellulose in…..lol. Same with Erfa…..sigh….
    I dont think its a conspiracy as isnt Erfa made in Canada…….well spain now to be precise!!
    Now WP is back what is that like? I was on WP before they stopped production…

    Reply
  57. Carol

    I had previously posted that I got the NP 60’s that smelled like cat urine and were grayish colored. I went to a different pharmacy on Monday and was able to fill a 30 day rx with what appeared to be the good pills because they looked normal. They do have a strong taste and smell which has gotten stronger each day but not like cat urine and the texture is different. I am now getting random red itchy spots on my body and my nose, eyes and arms itch like crazy. My face is getting numb spots and my adrenals are surging which I haven’t had in years. This afternoon I took one of my good ones and had no itching, numbness or adrenal surges.

    Reply
  58. Thy Roid

    I’ve been trying to source a compounded version of NDT and finally found a pharmacy who can do this. The pharmacist told me that this porcine thyroid powder has been “unavailable for a long time and is only just now back on the market…”, which is interesting and I thought I would share this fact with the rest of you.

    What do you make of that? Can’t be the FDA thing with the Chinese supplier can it? This pharmacist told me they were getting their powder from Houston TX (doesn’t mean it’s not Chinese but possibly reduces the chances a bit).

    Reply
    • Thy Roid

      Follow up: I had a chance to discuss this issue in a later telephone call with the pharmacist. I was told that last year a shipment of NDT powder from China was initially approved or passed inspection. This powder made its way through several wholesalers in the US who likewise somehow approved this powder and sold it. This is the same powder that all commercial NDT pill makers use as well as some of the pharmacies that do compounding. Eventually the FDA discovered issues and cited the Chinese facility and that powder was withdrawn (as well as WP Thyroid tablets), which has already been discussed here.

      This pharmacist suspects that some of that powder made it into pills that were released to pharmacies and eventually sold to patients. Someone mentioned that the expiration period is typically two years and that the expiration dates noted in our work are largely 2020 dates. So pills manufactured in 2018 might just now be getting to us (or perhaps being dumped on us due to the shortage in new NDT powder?), and those pills might have contained the withdrawn powder.

      One possible explanation…

      Reply
      • Lynne

        I am concerned about the change as well—
        I am especially concerned about sources in China as there is not the same quality control there as in the US.

        Reply
        • Dee

          Another theory, from a medical friend, suggests that a great deal of the porcine powder was supplied by Puerto Rico.
          The hurricane a while back wiped that source out completely. So it is getting more difficult.

          Reply
  59. Lorraine S.

    yall trippin my NP thyroid been smellin like cat piss for a whole year now
    my most recent pickup actually smelled not terrible but i concur it does not seem to dissolve sublingually as easy

    Reply
  60. Jean N

    Has anyone actually received replacement pills from Acella? I was told they were sending a new bottle to my pharmacy, but nothing yet.

    Reply
    • Amy

      Jean N. Nope! And I was promised the same thing…new pills, either at the pharmacy or my door. Probably for a cost, saw a few say they got charged upon receipt. Even answered a bunch of questions from their “health department” (Billerica, Massachusetts phone #) Got a script for Armour, and if that doesn’t work adding in thyrovanz or switching to 2 synthetics, as I’m pretty much done dealing w/this company. They are denying anything has even changed, it’s absurd, nature/WP fiasco 2.0!

      Reply
  61. Judy Feyen

    My husband has been taking Acella NP thyroid 120 mg for about 9 month now and has had better #s then when he was on Naturethroid. He initially did well on Naturethroid until they changed, then his TSH shot up to 8. He just refilled his NP script and they are larger and have specks, so I assume they are the new batch. Our pharmacy fills their own bottles and I dont see a batch #. We are going on a 1 month vacation so I don’t know what to do at this point. He has kidney issues as well as high BP. When his thyroid meds are working his kidney function is better and so is his BP ( he does take BP meds too). Have those who have been chewing them found them to be more effective. I guess I could call his Dr and relay my concern, but the Dr. seem to be the last ones to realize there a problem. Plus I wouldn’t know which NDT to ask them to switch him to. Has anyone had luck with Armour lately?

    Reply
    • Cincolo

      I’ve been chewing mine for the last 6-7 days and am feeling much better.

      Reply
    • Jenny

      I have been on Armour for the last 2 months and am doing really poorly- symptoms all over the place: Hypo and hyper… can’t get up in the morning, weird rashes on hands and scalp. Depressed and anxious. Heart tightness… constipation and then the runs…each pill seems different… I am probably going to have to go on synthetic…I don’t know of any other choices? Was on the natural pig thyroid for 9 years…. Armour, Naturethyroid, Np and now Armour again – nothing seems to work… I don’t know what choices I have left?

      Reply
  62. OM

    Lots more reports about problems with NP on Drugs.com. Seems the only thing all of the NDT thyroid hormone drugs made in USA have in common is the USP porcine thyroid. Also noted that some compounding pharmacies can no longer get the USP thyroid hormone for compounding. Some had used thyroid from China prior to this. Wish we could have the USP thyroid hormone that is used in all of the NDT drugs analyzed!

    Reply
    • Janie Bowthorpe

      It’s being explored…

      Reply
    • Janie Bowthorpe

      The sad part of what’s on drugs.com is that it’s loaded with people who were underdosed or had an iron or adrenal problem…and don’t get that it’s NOT the NDT that’s the problem..it’s what it’s revealing from any of the latter.

      But now, we have a truly lousy NDT with “NP Thyroid” by Acella–it’s now changed and sucks, all while Acella says they changed nothing and only focus on the size, smell, etc. So when you read what someone says, you also have to note if they mention the horrid smell, the awful taste, the large size tablet, specks. Those tablets represent a change to what’s inside—a now VERY bad product causing a massive return of hypothyroidism, as well as nausea, repulsion, burning when they swallow, etc.

      Reply
      • Hadassah

        Janie I would love to know which NDT do you recommend now after the NP fiasco ? Are you thinking about synthetic T3 also ? If yes which one would you recommend ?
        It’s crying shame what is being done with our thyroid meds that worked so well for us .

        Reply
        • Janie Bowthorpe

          I stopped recommending them. Just not seeing enough strong and consistent positive results since every single one of them has changed and not giving the quality results they used to. It’s irritating. But there are some individuals who feel they are doing well on compounded ndt or Armour. Hardly any doing well on the others. So I just leave it up to you. Also, being OPTIMAL on T4 and T3 could be good, too.

          Reply
          • Hadassah

            Thank you Janie . I guess going with synthetic T3 and T4 is the only option we have now I guess this is what they wanted us to do from get go . What a shame .

          • Karen SFerguson

            I understand why you don’t recommend them, but can you tell us which thyroid med you take? If I have to switch to another NDT (I’ve tried Armour, Naturetroid, straight T3, WP Thyroid and now on NP Thyroid) it would be nice to know what meds work for others.

          • Janie Bowthorpe

            I’m still on the former-working NP Thyroid.

  63. Laurie

    I talked to my pharmacy today about NP Thyroid. The person I talked to said she was not aware of any problems with NP and that there have not been any recalls. She seemed surprised. I let her know that I had hypothyroid symptoms and that the pill did not seem like what I had been taking. The smell and taste were different and it tasted toxic. My lot number for the new batch of 90 that I have is M327B19-1

    Reply
  64. Suzette

    Hello,
    I have been in NPThyroid for several years but just picked up a new 3 month script only to find they taste like iodine has been added… a LOT of it. I too, wrote Acella only to be told they haven’t changed their formula. I haven’t yet gotten the Lot# for you but I will. However, I wanted to mention something that may help explain why these companies are changing their formulas. Actually, there are two reasons that I believe this is happening. You may think I’m a conspiracy nut when you read the second one. The first reason is to make the tablets longer acting. Many of us began having trouble with Armour not working. Then we found out they changed or added a filler: some form of cellulose. Cellulose is a fiber and is being used to slow down the absorption of the thyroid hormones in the medication apparently to make it more like a time-release product. This works for some people, but for others its a disaster. I guess some people cannot break the cellulose down enough (I’m one of those people) to get the thyroid so its like taking your thyroid med with food. The other reason is the conspiracy one. I believe that all these manufacturers aren’t just waking up one day and deciding to fix something that’s not broken thereby losing revenue because so many people stop buying their drug. It doesn’t make sense does it? So, what would make them all do this? Well, we know the FDA and many medical establishment people do not like NDT. They SAY its because of one thing or another but they cannot prove synthetics don’t also have some of these issues, if they even exist. So then why don’t they like NDT? Simply because its a natural product. Look at what they have been doing to the natural supplement industry for the last 10-20 years. They do not want us taking naturals. So, do I believe they are “leaning” on manufacturers of NDT? You bet I do. They know if they just suddenly pull them off the market the uproar would be huge. But if people decided themselves that NDT was no good, or didn’t work for one reason or another, they would be forced to go to synthetics. As an aside, Hillary Clinton takes NDT, I believe its Armour. Wonder if she’s having problems.
    Anyway, that’s my two cents. I am very concerned about the iodine taste/smell because women who are past menopause should be careful taking iron as it can raise their risk of heart attacks. At least that’s what I was told years ago. Maybe that has changed but since I’m past that age and have no thyroid, I am wondering what to do. I have only been on this new bottle for about a week so I don’t know if I will have any problems but the fact that it tastes so strongly like iodone has me very concerned.

    Reply
  65. Suzy

    My labs were bad with my older batch of NP. The new prescription is different but I’ve been doing better. Maybe just a bad batch.

    Reply
  66. Emily

    In response to your e-mail:
    1. How do you know that you are reporting on the CHANGED NP Thyroid tablets?
    My new tablets are thicker, speckled and smell like ammonia (cat urine)
    2. Comment with the lot number for the bottle of what are clearly CHANGED NP Thyroid tablets
    Lot #M328S19-1
    3. Comment with the expiration date for what are clearly CHANGED NP Thyroid Tablets.
    Bottle says EXP 07/30/19, but I think that’s a typo as it was filled on 07/30/19
    4. State the city, state, country, and name of store/website where you got the changed tablet
    Kailua-Kona, HI, USA, Walmart

    Reply
  67. Melanie and David R Schrand

    Hi there, I have been taking np thyroid for a couple of months and although I am still not feeling well, something is wrong because all my symptoms are worse and I was at least stable before. I don’t know if it is the Np thyroid or the fact that I lowered it and added in T3 to lower my RT3. I don’t see a batch number only rx numbers, but they were filled in July 2019. Do you think it will be better to go on the synthetics then?

    Reply
  68. ELISSA JUNG (CUPCAKE)

    THIS IS NOT A COMMENT BUT A MEDICAL TRAVELOGUE. IN THE SPRING OF 2015 THERE WAS A NOTICE ON DRUGS.COM OF A ‘LABEL CHANGE’ FOR SYNTHROID AND ARMOUR. ‘LABEL CHANGES’ ARE NOT EXPLAINED NOR IS THERE ANY EXPLANATION GIVEN.I RENEWED MY SYNTHROID AND WITHIN 3 DAYS MY NORMAL BLOOD PRESSURE OF 120ISH SHOT TO 210 OVER 110. MY HEART WAS RACING, I HAD DIFFICULTY STANDING AND GENERALLY FELT HALF DEAD. STOPPED THE MED, WAITED TWO WEEKS, PRESSURE CAME DOWN, STARTED MEDS AGAIN…SAME REACTION AND STOP MEDS. IT TOOK ME A GOOD YEAR TO FIND THE CULPIRT(S). THERE WERE TWO ADDITIONS ADDED TO THE INATE LIST..ACACIA FOR PILL WHITNESS AND LACTOS FOR SWEETENER. ACACIS IS A SHRUB, IN THE SAME FAMILY AS ‘RAGWEED’. LACTOS COMES FROM DAIRY. I AM VERY ALLERGIC TO RAGWEED AND DAIRY…THEREFORE THE SEVEAR REACTION. WHAT ELSE IN THIS UNLISTED INATE ADDITIONS COULD EFFECT MY THYROID SISTERS? WAS A SUPPLIER CHANGED? WAS THE CLEANING OF THE PILL MAKING MACHINE NOT RINSED OFF? WAS THE PACKING MATERIAL INFERIOR? WAS THE NATURAL THYROID HORMONE TAKEN FROM A SUMMER ANIMAL? OR A WINTER ANIMAL. ROBUST/STRONGER IN SUMMER,WEAKER IN WINTER? MY SYSTEM WAS NOW TOTALY OUT OF WACK, PRESSURE WAS ALL OVER, FROM HI TO LOW WITHIN 2 HRS. STILL FELT LIKE DEATH WARMED OVER. WORKED WITH DAVID AT ACILIA, WHO WAS VERY HELPFUL BUT I COULDN’T EVEN HANDLE HIS LOWEST DOSE MED. HEART WOULD POUND, I WOULD GET THE SHAKES, COLD BEYOND BELIEF, AND FATIGUED AS LAST WEEKS OVER COOKED NOODLE. IT WAS AT THIS JUNCTURE I DECIDED TO BECOME MY OWN DR. I USED MYSELF AS MY Petri dish AND BEGAN TO RESEARCH WITH WITH A VENGEANCE. RATHER THAN ACCEPT THE INTERNETS ARTICLES I BEGAN TO READ THE PHASE ONE/TWO TESTS REFERRED TO AT THE BOTTOM OF THE PAGE. MANY TIMES THEY WOULD ADD ODD THINGS THEY SAW, NOT VETTED. HERE ARE SOME… HYPO CLIENTS SEEM TO HAVE MORE ALLERGIES THAN OTHERS. HYPO CLIENTS TEND TO GO GREY YOUNGER AND HAVE A HIGHER SEX DRIVE.(I CAN VETT THIS ONE). A SMALL SEGMENT OF CLIENTS WERE UNABLE TO CONVERT T4 TO T3 AND ADDING T3 SEEMED TO HELP. IT HAD ME BOUNCING OFF THE WALLS, IN DESPERATION I STOPPED ALL MEDS. SOME HOW I BEGAN TO FEEL BETTER BUT WAS STILL SUFFERING WITH THE AFTERNOON SLUMP. TO MAKE SURE I WAS HYDRATED I WOULD HAVE 5 OZ OF COLD WATER, A GOOD SPLASH OF LEMON JUICE AND A SHAKER OF SEA SALT. SOMEHOW THIS WAS A BIG BOOSTER TO MY FATIGUE, BUT I DIDN’T KNOW WHY. IT WAS CHEAP, HAD NO REACTIONS AND WAS PLEASANT TO TAKE SO I CONTINUED, BUT STILL WONDERING HOW COME IT WORKED. ONE DAY I WAS READING RECIPES AND THERE WAS A FOOT NOTE ABOUT SEA SALT THAT IT HAD THE TENDENCY TO ‘OPEN UP CELL WALLS’ TO ALLOW NUTRIENTS TO PASS THRU. THAT’S WHY MY CITRUS/SEA SALT DRINK WORKED. FLUSHED WITH SUCESS I DECIDED TO ATTACK MY ERRATIC BLOOD PRESSURE. SINCE I AM ALLERGIC TO SO MANY THINGS THAT IS WERE I STARTED. I FINIALLY GOT DOWN TO MY SUPPLEMENTS. I STOPPED ALL AND BINGO MY PRESSURE WENT BACK TO THE OLD 120ISH. IT WASEN’T THE VIT. IT WAS THE “PILL”!!! NOT THE CAPSULE. BESIDES THE WELL KNOWN ALLERGIES…WHEAT/GLUTON, DAIRY, EGGS,RAGWEED, PEANUTS LOOK TO THE TYPE OF CONTAINER YOUR MEDS COME IN. THE INATE FILLERS IN PILLS, TABLET COULD BE DOING YOU HARM…CHECK IT OUT.
    HAPPY RESEARCHING

    Reply
    • Niko

      Have you ever been checked for Mast Cell Activation Disorder?

      Reply
      • Jeanne

        Niko, most docs have never heard of MCAS. Both my daughter and my mom have it, and I was the one to diagnose it! Not a doc, but a 25 year RN Clinical Nutritionist.

        For any one wanting to know more, there is an excellent book by the MD who put all the puzzle pieces together and coined the term “Mast cell activation syndrome”.
        “Never Bet Against Occam” by Dr. Lawrence B. Afrin MD. Available on Amazon.

        Reply
  69. Debbie Kimbrell

    Has anybody considered the possibility that the manufacturers are telling the truth, and didn’t change anything? Perhaps the problem is that the composition of the source of the active ingredient (or maybe even an inactive ingredient?) has changed? I ask this because so many NDTs are problems now.

    Taking both NP Thyroid 120 and NP 30, my last refills were 4/26/2019. A month later, I was very, very ill with many symptoms I had never had before. Thinking I was overactive, I began decreasing, with no improvement, until I was only on NP 30. After seeing the picture of the changed NP tablets, I realized my NP 120 tablets were not changed – but the NP 30, the only tablets I was currently taking, were speckled, which explained why my symptoms had not disappeared. And now I had a TSH of 13 (where for many years it had been 0.1) !

    I am no longer taking any NP Thyroid.

    Reply
  70. Jim

    Just noticed this update from Acella ( https://stopthethyroidmadness.com/2019/08/22/uh-oh-np-thyroid/#respond ):
    NP Thyroid® Product Update
    8/30/2019 Product Update : Providing updates and feedback about your questions related to NP Thyroid® is important. Our customer service has reported an increase in calls and emails related to the odor or taste of NP Thyroid®. We are also aware that there are some comments about this on social media sites. At Acella Pharmaceuticals, our priority has always been, and will continue to be, to provide our customers with quality, consistent and cost-effective products. Our API is sourced from FDA inspected facilities, and we manufacture NP Thyroid® in the USA to USP standards following cGMP practices. As a result of the upheaval in the desiccated thyroid market in the past few years, we have had to upgrade and expand our production capabilities to keep up with increasing demand for NP Thyroid®. We do not use any API material sourced directly or indirectly from China or India. Rest assured that our formulation, specifications and exacting quality standards for NP Thyroid® have remained consistent. NP Thyroid® is a product derived from natural sources, and you may notice the odor, taste and shade of our tablets may vary slightly from batch to batch. It is important to note, however, that we test each batch of NP Thyroid® to ensure that the finished product is within the USP (United States Pharmacopeia) specifications for T4 and T3. We have found no indication that slight variations in odor, color or size of the tablets affect their content, quality or consistency.

    If you have any questions or concerns with NP Thyroid®, please contact us at info@acellapharma.com or (800) 541-4802. Moreover, if you experience a change in your thyroid related symptoms at any time, you should contact your licensed healthcare provider.

    Reply
    • Cincolo

      Funny how every time they say they need to update their production facility, the product seems to get screwed.

      Reply
  71. Ellen

    PU. I stopped taking NP Thyroid after my symptoms got the best of me. Aches, dry eyes, fatigue. When I called Acella, they said, “batches can be different but the standards are the same.” I told them to raise the bar. Their new “batch” smells horrible, tastes even worse, has a different size and look, and makes me feel worse than ever. How can that be acceptable?

    Reply
  72. sam

    sorry am too tired to read it all but i recommend thyrogold . its from organic pasture raised cows isntead of factory farmed GMO fed poor pigs

    . it works too.

    also eating all orgnaic [ grown in real soil [ not hydroponic, hydropinc does not ahve the nutrients that soil organic does plus does nohting for the environmnet ] relaly helps for good health and curing digestion problems .

    hope this helps wiht people having problems with the pharmaceuticals.

    am s till tired but at least feel much better than wiht the horrible synthroid

    Reply
  73. Cincolo

    I’ve been chewing my tablets the past 5 days and am actually feeling better. Contrary to what others are saying, my tablets are extremely sweet (with the porcine taste only if it’s stuck in my teeth). I drink extra water afterwards though to wash the taste out of my mouth. Mine don’t taste anything like they smell. I’m actually surprised they are so sweet. Naturethroid and Armour were never that sweet when I chewed them (after they were modified). I’m taking 60 mg and 30 mg tablets daily. Anyone else noticing they are doing better after chewing them?

    Reply
  74. Wendy Benton

    I had commented a few days back about my problems with the new Acella. I callled the company and they called me back and were very nice, asked a whole lot of questions and are going to get a sample of my pills. After I got off the phone with Steve, I poured out my pills and compared them to an old one. Could not really see much but then I took a closer look and noticed that only some of the new pills were a shade darker colored. I put a lighter one under my tongue and it was fine then a darker one and the taste was horrible and I spit it out. I have a call back to him to let him know.

    Reply
  75. Ann Rankin

    Hi Janie, To be on the safe side I personally will not consume any of the new tablets that are making people sick. It’s one thing to have the pills cause return of hypo symptoms. It’s another thing entirely when people are saying it is making them gag, become nauseated, have stomach pains, and burning tongue plus more! Why are some continuing to take a chance with their health and safety by taking them?

    Reply
  76. Laura Beckwith

    Not sure what to do, my ND changed my dosage from 60mg of NP Thyroid to 30mg of NP, 5mcg of liothyronine, the 30mg is the one with the change. I have been taking since the Labor day weekend, besides the already known changes, I chew my NP thyroid, and it’s foul tasting, and I feel like gagging. I think my stomach slightly feels a bit different after taking it as well. The taste/aftertaste stays in my mouth so pewtred.

    Reply
  77. Amyiable

    I called Acella, left a voice message in David’s message box explaining the problem with the new script for NP Thyroid as having little if any thyroid hormone in the 1-grain tablets. I gave him the lot number (Lot #M330C194) I received from Express Scripts. I stated my phone number in case he would want to speak with me. I explained that I had to switch to a different thyroid medication brand.

    Reply
  78. Catherine

    I just picked up an older batch of a sealed bottle of 100 pills of 30 mg from Rite-Aid thinking that I temporarily avoid the problems that have been emerging. The expiry date was 10/2020.

    I was horrified when i opened it and saw darker grayish tan pills. I opted to partially fill with a newer batch expiring 02/2021. So my hunch that the newer pills are a problem is not accurate.

    Could we create a list that everyone can update with batch numbers and expiry dates? Maybe we can figure out the problem that way.

    Reply
  79. Trudy Boccaccio

    Hi, this is very interesting, I am taking Thyroid from Thailand, would this be true about these also as I am not good at the moment, thanks

    Reply
  80. Kim

    Hi, I saw the video you posted the other day on fb and as many of us, share the same feelings.
    I’ve been wanting to know if you had filed a report to the FDA, spoken to a lawyer, have the pills tested at an independant lab to see the ingredients change. I ask because these are things I am planning to do but was curious ifthere was a class action suit already happening. I am upset that after 5 years and learning so much, I am not allowed to have the option of natural treatment. Tired of doctors claiming NDT doesn’t work because it’s inconsistant when it’s clear that’s the manufacturers. What can we do, how can we all get involved and stopthis madness and companies getting away with stuff. These NDT are prescribed because they are regulated, someone is not doing their job and we are paying for it!

    Reply
    • Melannie

      Hi, i so admire your courage and gumption to do all these things with the fda and the lawyers!

      But it may be worth reconsidering. First of all the fda and the medical community does not support NDT or prescribing NDT for thyroid disease. Second, NDT is not considered a real medicine by the FDA because it is so old it was never tested by the FDA and it was also never grandfathered in to be given status as a recognized medicine. So these two things combined make it very risky to contact the FDA and put NDT in their line of sight. We run the risk of them saying that the drugs are unsafe, unregulated and thus should no longer be produced or prescribed which is already what mainstream medicine is saying about NDT.

      In addition given that current prescribing guidelines recommend against NDT and that the drug lobbies, whose best interest is served by patent available synthetics (NDT can’t be patented), have major connections to the FDA in very profound ways, the FDA would have every reason to use this as an excuse to shut down NDT prescription and production.

      So in my opinion your courage and motivation are so wonderful, but it may be better to NOT to contact the FDA and instead work directly with the manufacturers to resolve this problem. Especially since Acella is interested and wants people to report about lot numbers that are causing symptoms. It means they are beginning to listen. So maybe let’s see what they can do 🙂 what do you think? – melannie

      Reply
      • Just Me

        Melannie, NDT was, in fact, grandfathered into the FDA. While they have not *approved* NDT, they do regulate and monitor it.

        Reply
        • Janie Bowthorpe

          Please provide proof that NDT was grandfathered in. We need it if this is so. If there is no documentation to back this up, I do want to remove your comment so as not to provide wrong info.

          I do remember a few months ago someone providing something, but sadly, I was in the midst of writing two books and very preoccupied.

          Reply
          • Kim

            When doing some research last week, I also found that NDT was grandfathered into the FDA.
            I looked in my search history. This is what I found:
            “FDA-Approved?

            Because DTE was developed before the U.S. Food and Drug Administration (FDA) existed, its legality as a prescription medication was grandfathered in. While it’s regulated by the FDA, it has never gone through the application process that was required of new drugs introduced to the market after the FDA was founded. This means that it’s not FDA-approved.”
            Source: https://www.verywellhealth.com/armour-thyroid-for-hypothyroidism-3233291

          • Janie Bowthorpe

            Unfortunately, a lot of articles and people make the mistake in calling it FDA approved.

            And that article is bad. For example: “There are slightly varying amounts of T4 and T3 in DTE, making them a less precise treatment option and potentially creating more difficulty in finding the correct dosage.” That is typical bs. For YEARS now, we have never had difficulty finding the correct dosage.

            And this: “Animals have different balances of hormones than humans. DTE contains a 4:1 ratio of T4 to T3; humans have a ratio of 14:1. This can translate into high T3 levels in people taking DTE.” Total bs. We have never, ever had an issue with the fact that pigs have more T3 than T3.

            Or this: “Because T3 is about four times stronger than T4, there’s concern that taking DTE or a synthetic combination of T4/T3 (levothyroxine and liothyronine) can temporarily result in thyrotoxicosis two to four hours after taking it.” The third bs. Years of our experiences have never found that the rise in T3 after taking NDT results in thyrotoxicosis.

            Once upon a time, someone with a huge and false bias stated idiotic things like this, and those comments get passed down to promote similar huge and false bias.

      • Kim

        I understand your point of view but it has been unsafe what RLC labs and Acella have done. Please correct me if I am wrong, but they are prescribed because they were going to be regulated. If not they would be sold OTC. Where is the quality control? No one noticed the color, smell and size are different? They should be held to the same standards, isn’t that the only way we can have NDT safe on a long term basis and more companies aboard, if they regulate the companies better so no one gets away with this? Like Mylan with the Epipen, it opened a whole new market and many companies jumped in to provide new epinephrine auto injectors and even nasal spray and a pill that goes dissolves under the tongue.

        I have already asked a friend I have in the pharmacy industry for independent labs that will test one from an old batch and the new one to see what is the difference. Once I receive a contact, I’ll have them tested. I recall Ms. Janie expressing her upset as all of us. I just want to be proactive and provide real solutions with real results. Many patients are still going to Naturethroid starting good finishing bad. And its been a year! I already struggle with so many other things in my life. I don’t think worrying if my pills this month will be a good or bad batch. It’s not fair for those who want to be productive in society. What other things can we do? Acella can’t be our only option. Never put all your eggs in one basket.

        Reply
  81. Catherine

    Hi. It would be helpful if everyone experiencing a problem could post the expiration dates of the bad batches received. That way, we can pinpoint approximately when the problem occured. Maybe that will help others.

    Reply
    • Cincolo

      I’ve been chewing my tablets the past 5 days and am actually feeling better. Contrary to what others are saying, my tablets are extremely sweet (with the porcine after taste). Mine don’t taste anything like they smell. I’m taking 60 mg and 30 mg tablets daily.

      Reply
  82. Laura Chrostowski

    Wow! I have Hashimoto’s and take NP Thyroid 30 mg tablets- 3 in a.m. and 2 in p.m., totaling 150mg/day. Prior to June, I was feeling fabulous! My April 2019 labs were optimal (FT3 176, range 71-180, and FT4 127, range 0.82-1.77), which they have been for over a year now after treating adrenal exhaustion. (Thank you, Janie! You saved my life!! Your books are my bibles! If not for you, my hashi’s and adrenal exhaustion would have gone undiagnosed for another 10 years, and I would have been 300 pounds by now!)

    I have noticed the smell of NP is a little bit stronger than usuaI. In June, I began to notice lower energy, and now, September, I get so tired in the afternoon that my eyes are closing, and I just don’t have energy. Weight loss has slowed, I’m feeling more hungry, and it seems I have developed a sensitivity to sun. I get red blotches on my face around my eyes when outdoors, and I’m always covered with hat, sunscreen, and sun glasses. I have been feeling so poorly, that I asked to be tested for Lupus; my ANA test was negative. It’s a relief to know that NP Thyroid is likely causing my symptoms, but I am so very disappointed in Acella. Before STTM, they were nobody, and they can become nobody again because we do have choices!

    I just had my labs done again on 8/29, but unfortunately, the tests have different names with different ranges, and I can’t interpret the differences: Thyroxine (T4) 7.8, range 4.5-12.0; Free Thyroxine Index 2.1, range 1.2-4.9; T3 Uptake 27, range 24-39. I don’t understand Thyroxine Index or T3 Uptake. So, if anyone can interpret these numbers and compare them to my optimal in April, that will tell how the new meds have affected my labs. My doctor has moved to a different practice, and apparently the tests are different. When I asked the doctor, I was told that the Thyroxine (T4) is actually Free T4, and the T3 Uptake of 27 was equal to FT3 of 170, which I don’t get, and couldn’t even interpret via google. Many thanks!

    Peace

    Reply
    • Janie Bowthorpe

      FYI: save your money. We don’t need total T4 (Thyroxine T4), Free Thyroxine Index, T3 Uptake. All we need is free T3 and free T4.

      No, just a “Thyroxine (T4)” is a total, not a free T4. No, T3 uptake is not free T3.

      Reply
    • Karen SFerguson

      I also take the 30mg NP at 150mg/day (3 at 6am and 2 at 3pm.) I really have not noticed any difference in the small or taste – I take them sublinqually. However, I am having major hypo symptoms, fatigue, hair loss and can’t figure out what is going on with me. After reading this thread I’ve put a call into my doctor to ask for thyroid labs. I had been on 3 grains but reduced down to 2.5 grains about 8 mos ago and was feeling fine. I’ve been on NDT for 10 years and it took me a few doctors and 2 years to feel human again and don’t want to go through it again. Life is too short, especially at age 70.

      I had been taking WP thyroid until the shortage and started taking the NP Thyroid. I’d go back to WP Thyroid, if anyone can tell me that it is working well after their comeback.

      This site is a life saver and I own two of the Madness books and considering getting their updated one. I stayed up late last night reading this entire thread and found it extremely helpful. I’ve not had any trouble getting my NP Thyroid and I get a 90 day supply via CVS mail order – as required by my insurance. The 30mg NP Thyroid tablets are very small – maybe an 1/8 inch in diameter – so not easy to determine changes without a magnifying glass.

      I hope to get labs next week and will update this information then. Again, I really prefer the WP Thyroid since it has few fillers – please someone post if the new WP Thyroid is working for them.

      Reply
  83. Sarah

    Hi, I’ll chime in here with my experience. First, I am immensely grateful I found this thread because this explains a lot for me. I actually just started NP thyroid back in June this year. I had a hard time finding a pharmacy that carried it, but luckily I found one that had it in stock–likely with the old formulation. When I refilled it 6 weeks later from a different pharmacy I guess I got the newer formulation. After the initial first 6 weeks on the old formulation of NP, my TSH improved to 2.9 (it was at 3.9 previously). I’m only taking 1/4 grain (15 mg /day) btw. Now fast forward to August. My hair is falling out like crazy, my period is SO out of whack and my TSH has increased to to 4.8 (higher than it was before starting this med). I obviously believe what people are saying here about the formulation change. I know I’ll be coming off this one. I’m very disappointed in the pharmaceutical industry in general. What is a reputable med at this point?

    Reply
    • Hadassah

      Can you please tell me what are the dates on the NP Thyroid bottles that have problems with so I can be on the lookout to make sure I don’t get them ? I’m due to get a refill and I don’t want to get stuck with thyroid meds that have problems . I would like not to revisit the hypo issues . If I can get the old ones with the good batch and dates still that have no problems I would love to see if I can still get them .
      Thank you in advance .

      Reply
    • sam

      i take thyrogold in case you want to try

      Reply
  84. Rachel

    The only fact a company looks at is their bottom line. As a consumer, the only action is to not buy their product which will immediately affect their bottom line.
    Unfortunately I just had a refill for 3 months but plan to send them back and cancel the refill from Express Scripts due end of October.

    If everyone boycotts NP Thyroid ( if its not working, it should not be too much of an issue), maybe then they will listen).

    Reply
    • Janie Bowthorpe

      Correct, the power that patients hold against this sanity of changes, gaslighting, and denials is to stop giving them your money.

      Reply
      • Christianne Pereira Giesbrecht Chaves

        Rachel this is a good idea, however it is still not good for us who have to find another options and we know changing meds is a pain and also takes time to reach the optimal. We are really in a hard moment. It looks like some synthetic “entity” is trying to push all us to synthetic only.

        Reply
  85. Ana

    Acella’s patronizing statement reveals a lot about the way they view the patients who depend on NP Thyroid to stay alive and have a decent quality of life. Their dismissal of patients’ reports on the changes in recent NPT batches as some sort of mass hysteria over a trivial variation in shade, odor and taste does not bode well for us. Do they think we’re going to fall for their paternalistic reassurances that nothing has changed? The fact is that recent batches of NPT have been substandard. The changes in taste and smell go beyond the expected variability, but by far the most critical change is that the active ingredients have been rendered inactive. We thyroid patients know this.

    If Acella continues to dismiss our reports, they’ll never try to figure out what’s causing this change. I think we need to keep contacting Acella and clearly emphasize that the main problem is that something has inactivated the thyroid hormones. Request that they please investigate and determine what’s going wrong. It’s not an exaggeration to say that, for many of us, our lives depend on it. We’re running out of treatment options.

    Reply
    • Janie Bowthorpe

      Excellent response, Ana.

      Reply
      • Dee

        Yes, excellent! And I am one whose life (and my family’s) DOES
        depend on it! As Janie knows, I even tried drying my own pig thyroid
        (from local butcher), but couldn’t find the chemical which takes the
        fat out! If I could locate that, add dextrose…well, I am desperate! 🙂

        Reply
  86. Victoria

    Here’s Acella’s NP update on their website from 2 days ago which passes the buck and doesn’t fix the problem, imagine that!…
    “NP Thyroid® Product Update 8/30/2019: Providing updates and feedback about your questions related to NP Thyroid® is important. Our customer service has reported an increase in calls and emails related to the odor or taste of NP Thyroid®. We are also aware that there are some comments about this on social media sites. At Acella Pharmaceuticals, our priority has always been, and will continue to be, to provide our customers with quality, consistent and cost-effective products. Our API is sourced from FDA inspected facilities, and we manufacture NP Thyroid® in the USA to USP standards following cGMP practices. As a result of the upheaval in the desiccated thyroid market in the past few years, we have had to upgrade and expand our production capabilities to keep up with increasing demand for NP Thyroid®. We do not use any API material sourced directly or indirectly from China or India. Rest assured that our formulation, specifications and exacting quality standards for NP Thyroid® have remained consistent. NP Thyroid® is a product derived from natural sources, and you may notice the odor, taste and shade of our tablets may vary slightly from batch to batch. It is important to note, however, that we test each batch of NP Thyroid® to ensure that the finished product is within the USP (United States Pharmacopeia) specifications for T4 and T3. We have found no indication that slight variations in odor, color or size of the tablets affect their content, quality or consistency. If you have any questions or concerns with NP Thyroid®, please contact us at info@acellapharma.com or (800) 541-4802. Moreover, if you experience a change in your thyroid related symptoms at any time, you should contact your licensed healthcare provider.”

    Reply
    • Janie Bowthorpe

      What is very noticeable is the emphasis that the calls are about odor and taste, and mention of size, with NOTHING about all the miserable ways the changed tablets are making people miserable and feeling sick…as evidenced by all the comments here..as well in massively in thyroid groups.

      Reply
      • Ally

        Empty words from the manufacturer. Symptoms are awful. Taking causes a gag reflex. It’s not easy to get in quickly to see a dr who is in demand; getting new lab results takes time. I contacted the manufacturer last week … the response was no response. Shameful business practice

        Reply
      • Victoria

        Janie exactly! That’s what I meant by… passing the buck/ignoring the problem/political/greed/BS/at our expense

        Reply
  87. Victoria

    Allow me to add my rant to this nightmare. I’ve been taking NP 90 mg desiccated thyroid for a year and doing well and I chew it before swallowing. I’ve taken 2 days of my latest prescription and it tastes awful like corn chips or dirty feet smell AND the diameter is smaller! WTH? So I contacted my Walmart pharmacy and they just acted like I was crazy because I chew it instead of swallowing AND they dismissed my concern because the letters and numbers are correct on the pill. Someone posted about Woodland Hills compounding pharmacy so I just emailed them hoping to switch to a compounded version which would be better anyway because there are no nasty fillers and because I’m running out of options! I’ve tried them all, I used to take Thyrogold and did well on it but I discovered last year they suddenly changed their fillers without telling anyone by adding coconut oil which I am highly allergic to! I can’t wait another day for Acella to figure this out and start having debilitating hypo symptoms return like people are posting here, I don’t know where else to turn, I’ve been dealing with this demonic political deception between pharmaceutical companies and their synthetic crap vs “natural” companies and their lies, hidden fillers, foreign manufacturers and shortages at our expense for 15 years and the “madness” never stops!! Who knows if compounding pharmacies are even on the up and up or taking kickbacks from somebody as well but here’s an article from Woodland Hills compounding pharmacy’s website on this subject Good luck everyone, I’m so “sick” of this crap, literally sick of it! https://www.woodlandhillspharmacy.com/acella-np-thyroid/

    Reply
    • Stacey

      That is exactly how I feel!! I have been trying to get NP filled for several weeks. It seems the major suppliers are not stocking NDT meds. I am soooo tired of struggling to get NDT. Switching to synthetic t4 & T3 and I’ll see what happens.

      Reply
  88. Jeff Garland

    In addition to taste and smell, one can no longer take the pill sub-lingual; that is, it doesn’t dissolve in your mouth. That’s what I liked about it most. I’m giving up on the NDT and switching to synthetic. Too much BS.

    Reply
    • Janie Bowthorpe

      As long as you use BOTH synthetic T4 with synthetic T3, and work to be optimal, you can be fine. https://stopthethyroidmadness.com/optimal

      Reply
      • Rachel

        This is very disheartening news! I had to switch from Naturethroid to NP thyroid because of all the trouble they were having. I just tried to fill a new prescription and I was told it was on back order which made me suspicious so I came out here to find out what was going on. I know that I still have the old ones from the size shape and color, but I only have a few left. Unfortunately I am allergic to any pharmaceutical synthetic medications like Synthroid. I had horrible joint pain the whole time that I was taking the Synthroid and Cytomel as soon as I switch to a naturally desiccated thyroid medication that horrible joint pain went away. Has anyone tried the compounding pharmacies approach? Are there any other alternatives? I am currently taking one and a half of the 90 mg NP thyroid tablets. How many grains would I need to get from the compounding pharmacy to have an accurate switch over?

        Reply
        • Janie Bowthorpe

          Yes, as long as you get optimal even on compounded, it can work. But also know it’s cheaper to dose yourself with the two synthetics. Either way. Study this: https://stopthethyroidmadness.com/optimal

          Reply
          • Rachel

            Thank you so much for the information Janie I will look at that page, but I will not go back to synthetic medications. I am one of those people who is Allergic to the 21st Century. Most people call it multiple chemical sensitivities or environmental illness, but I don’t like either one of those terms. They’re too depressing! 🙂 I know a compounding pharmacy would be frightfully expensive so I am looking into getting an over the counter Thyroid supplement should be an interesting time! Please know that I am praying for everyone out here who is going through this process. Thank you again and take care!

      • Rachel

        I also wanted to ask about thyroid glandular supplement options? I was looking at the Allergy Research supplements and they are frozen, then dried which is very good way to handle thyroid tissue. Do you know if anybody else has tried them? I do not have a thyroid, I had thyroid cancer in 2010. I need to get some idea about how much I should take as well. If anybody has any information, or if there’s some place online that I could look to get a better handle on that? Please let me know.

        I know that one of the things that would be a blessing is that I would be able to take a little bit every few hours during the day, which would be much more like my original thyroid process. If anybody has any information I would truly appreciate it.

        Reply
        • Just Me

          Rachel, you may do well with Tirosint. I can’t take Synthroid either. Tirosint is a synthetic t4 only with no and/or less fillers. You can add Cytomel or a time released synthetic T3.

          Reply
        • Janie Bowthorpe

          You could try it, but it contains an awful lot of cellulose, which blocks some of the thyroid hormones. Not too swift on their part. As far as how much, we just watch our free T3 and free T4 and get optimal. https://stopthethyroidmadness.com/optimal

          Reply
      • Lyn Newton

        I was on Synthroid for 27 years and for 27 years I had all the hypo symptoms but my labs looked good so the docs wouldn’t do a thing. I did not know I had any other option during that time. Since then I have been on several different NDTs; Naturethroid, Armour, WP and now NP. I had an integrative doc talk me into trying Tirosint. Besides being expensive, I felt TERRIBLE ON IT. I have MTHFR genetic mutations and cannot convert synthetic. Synthetic is NOT an option for me!

        Reply
  89. Stacey

    I hope they fix the problem with NP however there is also the problem of getting it filled!! Every Pharmacy I have checked with can’t get it. I’ve tried local, mail order etc with no luck. This constant problem with NDT meds is just wearing me out!! My doctor is very open to my requests but I don’t even know what to ask for. Are there a lot of problems getting refills also??

    Reply
    • Just Me

      It’s possible if you tried in the last few days, Acella voluntarily recalled the recent batches which weren’t working. We can hope. Personally, I’m going to Armour.

      Reply
      • Emily

        Just Me, I haven’t heard about a recall yet. Can you please provide additional information? Thanks!

        Reply
        • Just Me

          Emily, I have no information. I made a suggestion. Sorry I wasn’t more clear. Like, maybe the reason people can’t get NP is a possible recall?

          Reply
      • Stacey

        I have been trying to get NP filled for several weeks. It seems the major suppliers are not stocking NDT meds. I am soooo tired of struggling to get NDT. Switching to synthetic t4 & T3 and I’ll see what happens.

        Reply
    • A Wright

      YES!! It is maddening trying to get filled. I usually have to get partially filled until they get more in, which of course costs more money. Ridiculous. I don’t even know what “normal” is anymore.

      Reply
  90. Stephanie

    This is all frustrating. I have hoshimotos and was put on armour for low t3 and barely within range t4 low end also. Anyway the armour did not give me anymore energy after being on it for about two months up to a full gram. My t3 went high and tsh was super low, t4 was within range. I started having all kinds of itching and rashes, swelling, and overall I’ll feeling. I was going to ask to try another type of natural thyroid as I was wondering about gluten and corn in armour. What do you suggest I request?

    Reply
  91. Dee

    Acella customer service actually called me and spoke with me for
    about 20 minutes! They are going to ask Walgreens for some of the
    last lot number to test it.
    That is amazing, since Forest Pharm. never seemed to care,
    when Armour was reformulated in 2009!
    Keeping fingers crossed.

    Reply
  92. Melinda Scifres

    I haven’t felt the same since I switched from Armour Thyroid to NP Thyroid and I’m wondering if it because the fillers and made of corn? I’m allergic to corn and then all the
    Corn is GMO. I feel better when I forget to take my thyroid pill. Less swelling, inflammation and pain it seems. Anyone else experiencing this?

    Reply
    • Janie Bowthorpe

      Melinda, yes, if you have issues with corn, guess it’s a possibility for you. Or you are underdosed. Underdosing ourselves always backfires and causes problem.

      Reply
  93. Christianne

    I am really lost with all that!!!! I am having a hard time try to reach the optimal but it is taking ages. I’ve trusted the endocrinologist last year and it was definitely not good (TSH narrow minded, just accept TSH as lower as 0.5), I have an appointment with her on the 17th and probably will be the last one once my TSH was 0.02 in July 18th, Free T3 2.6 and Free T4 1.51, Reverse T3 19.3. I wont care about TSH anymore and tomorrow I will have another results coming up. I can post here for suggestions.
    Now I am on Tirosint 100mcg, NP Thyroid 45 mg (just increase from 30 mg, on Aug 26th after the blood work) and Cytomel 2.5 in PM. I know that probably is not enough T3, hair NEVER stops falling!!! I had fatigue and need a nap almost every day this last week, I also had my period last week. I know Janie told me once to decrease the Tirosint, but now???? I don’t know what to do anymore. Switch to Armour? Increase the Cytomel? Both? I wouldn’t like to stay only on synthetics. I still have NP Thyroid for a while, I didn’t see any difference. This week I will receive a new refill from NP thyroid 30mg. I will check and post here how are the pills.
    Any thoughts?

    Reply
    • Janie Bowthorpe

      Christianne, we always have to lower T4 when RT3 is high, otherwise we get worse. Second, we nave to treat the cause. https://stopthethyroidmadness.com/reverse-t3 And it’s hard to comment without knowing your free T3.

      Reply
      • Christianne

        Janie thank you for your quick answer.
        Here are the last lab results that I just received today after this post, it was done in August 26th.
        TSH -0.02 Free T4 – 1.25 Free T3 – 2.3 Reverse T3 – 15.9 TPO – 49 (has been decreasing)
        Iron – 47 Ferritin – 77 TIBC – 246 Iron Sat -19% UIBC – 199 Iodine Serum – 47.5 Iodine Urine – 99.7.

        This is the blood work I have posted above from July18th
        TSH – 0.02 Free T3 – 2.6 Free T4 – 1.51 Reverse T3 -19.3.

        Reply
  94. Rima

    PS, Reporting this to the FDA will just fuel their fire. They want to do away with all “natural meds” and this will just make them clamp down on naturopathic medicine all the more harshly.
    I suggest we keep reporting to Acella (David said that lot numbers are VERY IMPORTANT).
    Let’s support them in fact finding and in keeping us supplied with good, reliable thyroid medication!

    Reply
  95. Rima

    Acella update!
    I just got off the phone with David Margulis at Acella. He is most appreciative of my detailed emails and we spoke for almost 13 minutes. We are working out a plan to get this “bad” prescription, lot number M330E10-1, back to him for analysis.
    I gave him the link to this blog and he will read what we are saying. He is very familiar with Stop the Thyroid Madness and wants to know what we all are reporting.

    Reply
  96. Kim

    Has anyone contacted or filed a complaint with the FDA?

    Reply
    • Janie Bowthorpe

      Unless something has changed, NDT is considered an unapproved drug. So complaining about it to the FDA comes across risky. We could be wrong, but worry about it.

      Reply
      • Janie Bowthorpe

        So the power comes in expressing extreme disappointment to Acella, and stop buying it. They are surely going to lose a lot of income, which seems like the most powerful way to send a message to them that they need to go beyond just saying they changed nothing and look deeper into this. Something definitely changed and horribly so.

        Reply
        • Ellen weir

          Thank you. Just found some older NP pills and they are different in size and smell. The date on bottle says 5/26/19, but I just got refill in last couple of weeks. Went through all changes and screwed ups in last 30 years. What do you think of Woodland Hills compounding that claims no synthetics. I’m hypo again and on HC . Tried synthroid.bad. I’ll make calls Tuesday to damn Acella

          Reply
      • Dawn Kaplan

        So on Acella’s NP Thyroid web page, at the bottom is written, “To report suspected adverse reactions, contact the FDA at (then the phone number and website of the FDA is listed). Not to be paranoid, but is this a set-up? This is crazy!

        Reply
  97. Andrea

    Okay, just got my latest labs back, and my head is spinning. TSH is – wait for it – .04L (reference range 0.40-4.50 mIU/L). Say what????!!!! I was .13L in July on same dose of NP (90 mg/day). But it gets better (she says sarcastically)….and more confusing….! My Free T4 is 0.9 (reference range 0.8-1.8 ng/dL, and my Free T3 is 3.5 (reference range 2.3-4.2 pg/mL). My head is spinning right now. How can I be hypo with such a low TSH? And yes, something’s wrong with NP, for sure…
    In the meantime, for some reason the report had not included the Reverse T3, so I have just requested that from the lab. Don’t know if that will help to figure this out though. Anybody…..?

    Reply
    • Just Me

      Andrea, look around STTM. You will learn that TSH means absolutely nothing when on NDT. It’s a pituitary hormone, not a thyroid hormone. That being said, everyone who has taken NP recently is tanking which means that there is definitely something wrong. I hope this gets straightened out ASAP.

      Reply
    • Tracey

      I have had the same exact experience Andrea. TSH going down on the same dose of NP, but feel the worst I have felt in a very long time. My NP after recent refill literally makes me feel like I am ingesting poison and rotting from the inside out. Found some old (and expired) NP in my closet. Been on this 2 days and feel like a completely different person. It has to be something in the fillers. It truly is bizarre.

      Reply
  98. Rima

    Good morning to you all!
    I had an interesting experience at Walgreen’s yesterday: I took my “new” bottle of 60mg NP, 8/22 from Walmart (distributed by McKesson), lot M330E19-1, to the Walgreen’s pharmacist. We compared those tabs to some of what I had left from my previous bottle, and to a fresh bottle lot M330C19-6 (dist. by Amerisource). My old script & the Walgreen’s product looked and smelled the same, quite different in color, from the Walmart product. The pharmacist said so immediately without my prompting! I bought a few from Walgreen’s and tested that this morning by chewing as normal. It tasted the same as the old ones.
    So far, I have not heard back from my phone calls or emails to Acella. My next attempt will be to offer to send the script from Walmart/McKesson to Acella so they can see the difference. Will report back here.

    Reply
  99. Amyiable

    Please add me to the count of those having problems with NP Thyroid. This became noticeable with most recent script from Express Scripts. The 2 grain tablets were not available so the new script is for 1 grain tablets. I felt bad after just a few days, so flipped to an older batch and felt better. I’m back on the new batch and can see things are very wrong so I went to your STTM website. I sleep 8 plus hrs and have trouble staying awake during the day. How can I keep a job with this? In addition to heavy fatigue, and brain fog, I have depression without cause. Wanting to eat all the time. Also allergy like symptoms in throat. I do not see specks in the new tablets and can’t comment on smell or taste, but something is very wrong, I am not in a normal state at all. Thank you Janie, thank you! I’m going to email my doctor and ask for a switch Nature-throid.

    Reply
  100. Linda

    I am new to NP Thyroid. Had a partial thyroidectomy in 2004, and was prescribed Levoxyl 100mcg. Was happy with Levoxyl until husband went on active duty and Tricare would only give Synthroid. Felt so sick on Synthroid, for the first time in my adult life thought I needed to call 911. Returned to Levoxyl when it came back. In the mean time noticed symptoms, thinning hair, sore joints, irritibility, etc. Now back on Tricare and was told no longer would be allowed to fill at pharmacy on post, would need to use Express Scripts. Since the cost to me was the same for Levoxyl and NP decided to ask to try natural. The first thing I noticed about my pills, was prescriged 90mg, is the terrible smell, thought this might be normal, first bottle. Commented to my daughter several times how awful they smelled and wondered if I smelled with summer heat. Had labs on 8/26, my tsh is 0.14, Free T4 0.8. Dr. reduced my dosage to 1 Gr. Received this from Express Scripts today. My first fill, 90MG had the normal tan color and smelled terrible. New fill, 60MG are a light tan color, smaller than 90MG and have what I would consider a normal smell, have to put your nose to top of bottle to smell anything and it is in no way offensive. The first fill 90MG could be smelled across the room. Like I said I had not idea this wasn’t normal, I expected some smell being they come from pigs.

    Reply
  101. Susie

    I am trailing off on another theory or concerning issue with the production of NDTs. Last September (I think) Smithfield Farms the largest pork producing farm in the US was bought by a Chinese firm. The hogs are still raised in the US but the processing is done in China and then sent back to the US. Maybe the standards are not as stringent and then the glands are too long in transit diminishing quality and effectiveness. If we can confirm that all our sources come directly from US processing plant, then we can breathe easier on that theory, but in the meantime it is something to investigate.

    Reply
    • Susie

      ok, with a little investigation, Smithfield Foods was sold to a Chinese company back in 2013, but it appears this company processes here in the US? so if that’s the case that’s a better scenario. But sitll yet. if they are a source for NDT production, then is the quality and handling the same?

      Reply
  102. Maria

    My pharmacy switched me from Armour to NP Thyroid (without notice) and at first I was upset. Did some research and thought I’d give it a go and was happy that the cost was less since my insurance won’t pay for it. Got a refill in July and only started taking it recently and OMG it’s VILE. Seriously disgusting. I take 90 mg cut in half once a day and chew it and haven’t had an issue tolerating it or the taste. But now? I can barely gag it down…and just what the heck am I putting in my body? I’ve only been on this reformulation for a few days but I am worried. My pharmacist didn’t know anything about a change though she said if there were one, they would be required to notify customers, and no such notification was sent to them from Acella. Why is this even allowed?

    Reply
    • Angela

      Ok now I’m completely freaked out. I was on Naturethroid a few years and couldn’t find it and my levels went crazy. Finally researched and changed to NP. I’ve only been on it about 2.5 months and not optimal yet but now I’m so afraid of what this might mean. Please please tell me there is a viable reason for this 🙁

      Reply
  103. Dawn Kaplan

    I did my own experiment. I took the new pills this morning (90 mg with a 15 mg), crushed them and sprinkled dextrose on top. Immediately I had ringing in my ears, heart palps started a few minutes after, feeling like my back was on fire. About a half hour later, bloat, large tongue, brain fog, muscle aches.
    I called a compounding pharmacy near me, talked to the pharmacist, he said to bring in the old and new pills. I went and he spent about 20 minutes with me. He definitely said the size, smell and color were different.
    His thoughts: Acella changed the filler ingredients. Possibly removing the dextrose and/or mineral oil and using a less expensive additive, making the pill less compactible, changing the color, size and smell.
    He also said he has not been able to get porcine powder for over two years, so could not make the compounded version even.
    Now almost 4 hours after I took my morning dose, ringing in ears subsided, have muscle aches, fatigue. Brain fog gone, feel okay, not great.

    Reply
    • Janie Bowthorpe

      Wow, Dawn, you are quite the trooper for trying that experiment. Hope you get back to normal soon! Something is clearly wrong.

      Reply
      • Dawn

        Haha! Thanks Janie. I figured I have the nightmare pills, why not do it myself? Took my old pill for the afternoon. Have teen-agers at home for the long week-end. I need to be able to function. I can’t believe we’re back here with this nonsense.

        Reply
    • Christina

      I’m having issues as well. My 30 mg taste foul. They definitely are off. I’m feeling very run down. The pharmacist didn’t even know there was a change.

      Reply
  104. jacqueline collins hullar

    Janie, To be as scientific about this as possible, what do you recommend we all do to verify what is happening? I am about to start my first “new/bad” batch of NP Thyroid. I have blood work from last month (almost optimal) based on being on the old version of NP (And Cytomel) on the same doses for over 6 months. ***How long should I take the new version of NP Thyroid (without changing anything else I attacking) and then re-test? I am a member of Adrenal Fatigue and Thyroid care and also their Experiment group on FB, so I will post about this there, with my before and after test results.

    Reply
    • Janie Bowthorpe

      The negative symptoms going on with the changed NP are already verified by the widespread reports. We have no report of anyone doing well on them.

      Reply
  105. Angie

    I am on Armour as I can’t get NatureThroid here anymore. It’s been on back order because the manufacturer is in Puerto Rico and apparently their facility was damaged in a hurricane. That was over a year ago and I still can’t get NatureThroid. My latest batch of Armour does taste and smell pretty bad. I didn’t think much about it until I saw this because all meds smell and taste bad to me. I’ll ask my pharmacy who the manufacturer is. Now I’m wondering if I shouldn’t try a combo of something like levothyroxine and cytomel. Also, lately I’ve been wondering how the pigs are raised and killed. If they aren’t being humanely treated, I don’t know that I’d want to use Armour anyway. But that’s another issue for another day.

    Reply
  106. Diana

    I got the new NP, and it smells and looks different. Scared to try it after the nightmare I went through with NatureThroid. One by one, they all go bad. Either they’re all getting their raw materials from the same place, and the source went bad, or there’s something shady going on. We need an investigative journalist or someone who can get answers.

    Reply
  107. Claudia

    Any chemists and/or pharmacists out there? Some of you still have the old (smaller and non-stinky) pills AND the new (bigger and smellier) ones? How would one go about having the two looked at and compared?
    I too noticed the new (bigger and much smellier) pills when I got my new bottle mailed to me the end of May. The ones before were just fine. Unfortunately I was in the middle of packing for our vacation and I used up all of my old (good) pills. Once back from vacation I started the new batch. Since then my T4 has been flagged low (???) and I’m feeling super hypo, just like all those years ago, when I first started out with symptoms. Thyroid and neck area ache, and so tired! I was perfect before and now back to my “mystery illness”!!!??? I got the lot# from my mail order pharmacy and have left 2 voicemails and one email for Acella. Will keep you posted!

    Reply
  108. Dawn Kaplan

    I was the one that posted about crushing the medication and adding Dextrose (dextrose transports the medication quickly into the bloodstream). I am wondering if anyone who has the reformulated pills have tried this? I have about two months left of the old pills so I have not. Just curious, as this little trick worked for me for many years when Armour reformulated years ago. Thanks to anyone who has tried this and responds.

    Reply
  109. Lo Vetta Bosworth

    Not sure where to put this. I just watched a copy of your video about NP Thyroid. Thank you for all you do. I’m trying to help you, as you requested. I take NP Thyroid by Acella. My current prescription is from May, so currently good, but worried as I just got a new prescription from Dr I haven’t filled yet. 😱
    I saw a post on TPO60 that sounded like a possible answer to the X, but I can’t believe you haven’t seen this already. I’m sure you’re too busy to read as many posts on different thyroid sites as I do, so with the possibility of being redundant I’ll share it here. Emily?? Posted the following last week.

    Regarding the changes to NP, someone mentioned this in one of the threads so I thought it might be worth bringing to the forefront. According to GoodRx, some NP is being manufactured by AvKARE (see attached screenshot). I wonder if the new smelly batches were made by AvKARE and not Acella? Also, as someone else has mentioned, it appears that Acella’s website no longer states that NP is made in the USA. I just checked the prescription insert and its says “Manufactured for” (not by) Acella, so I wonder where it’s being made?

    Reply
    • Janie Bowthorpe

      Yes, I am horribly busy, but I did see that! And someone did report it to a guy at Acella.

      AvKare is often used by pharms to produce their specified products.

      Reply
      • Ana

        AvKARE is a repackager not a manufacturer of pharmaceuticals. If you google them, you can pull up some legal troubles they’ve had. The VA used them for a time to supply generic drugs but stopped after visiting their facilities and finding them to have unacceptable practices. This raises questions about what company AvKARE subcontracted to manufacture the NP Thyroid. I also think there has been some change in the way the porcine thyroid powder is being processed. Naturethroid, WP Thyroid and now NP Thyroid have all had a similar diminishment in potency. That could at least partially account for the change in taste and smell and explain why RLC Labs and Acella have both insisted that they haven’t changed the formula.

        Reply
        • Kriss

          Well, that’s not good news about WP. My kiddo was on it until the shortage and then we switched to NP. We noticed he was doing well around January 2019, so we went on the Keto diet and he lost 50 lbs, BUT he’s back to his old habits of being hungry, has gained 10 lbs, feeling like crap and he noticed the NP pills stinking more than the normal smell and tasting horrible. I checked last week with a compounding pharmacy that I use, and they have WP back on their shelves, but now I’m wondering if that will make a difference. Should I try and go back to WP for my kid’s sake?

          Reply
  110. Abby

    I’ve spoken with both customer service and the pharmacist at Acella about a week and a half ago). They are supposed to be working with my pharmacy to send me a new script and take the old one back for investigation but so far no new script. I left David in customer service a message today asking when I would get my new script but no return call.
    I had a little over a weeks worth of extra 1 grain and I have felt so much better. Sadly I go back to the nasty 2 grain tomorrow. I even filled a new script and it’s the same:(

    Reply
  111. Michelle Sarchiapone

    My lot # is N329E19-1. Refilled on Aug 20th….though I think the previous batch was also not effective even though it didnt have the same weird taste as my symptoms returned around then (end of July early August). New batch tastes horrible. In comparision I had a few days worth of 15mg tablets left over from Feb 2019 that as soon as I took them, I felt back to my old self. That bottle was clearly marked Acella with a NDC # of 42192-327-01? That medication had no taste or smell. The July/early August refill had a strong piggy smell, and the latest refill tastes like insecticide.

    Reply
  112. Meaghan

    I, too, switched to NP about 8 months ago due to the Nature Throid crisis. I can’t explain it but I immediately felt horrible once switching to NT. I could tell immediately that something was off with my recent batch of NP. I was feeling not perfect but good enough. One day on the new NP and I had some dizziness and extreme anxiety rev up. Now I am extremely sensitive and aware of my body, and probably slightly hypo yet, hence the almost immediate reaction. I think it just absorbs differently somehow. I Contacted Acella and they asked for my pharmacy to get the lot #. Never heard back from them.

    My plan is to use up the good NP I have and switch to Armour. The “bad” nature throid time for me was absolutely debilitating. Don’t wanna do that again.

    Big sigh. Not sure what to do about this but it put me into a complete tizzy and panic. “Not again!” I was just starting to be able to handle working again. Ugh!!!

    So yes, just another one to confirm that the new NP is not the same.

    Reply
  113. Alex

    Acella says: „We do not use any API material sourced directly or indirectly from China or India“.

    All NDT did work… as long as API material was sourced from China or India…

    I have 5 bottles of NP: 2x 1/2 grain, 1x 1grain, 2x 2grain. The only one has LOT M330K17-3. The other bottles have no LOT numbers. I only could find the Rev. numbers inside the paper „Lift here“. I don’t know if this numbers are important.

    Reply
  114. Terry

    Product Updates & Availability
    NP Thyroid® Product Update
    8/30/2019 Product Update : Providing updates and feedback about your questions related to NP Thyroid® is important. Our customer service has reported an increase in calls and emails related to the odor or taste of NP Thyroid®. We are also aware that there are some comments about this on social media sites. At Acella Pharmaceuticals, our priority has always been, and will continue to be, to provide our customers with quality, consistent and cost-effective products. Our API is sourced from FDA inspected facilities, and we manufacture NP Thyroid® in the USA to USP standards following cGMP practices. As a result of the upheaval in the desiccated thyroid market in the past few years, we have had to upgrade and expand our production capabilities to keep up with increasing demand for NP Thyroid®. We do not use any API material sourced directly or indirectly from China or India. Rest assured that our formulation, specifications and exacting quality standards for NP Thyroid® have remained consistent. NP Thyroid® is a product derived from natural sources, and you may notice the odor, taste and shade of our tablets may vary slightly from batch to batch. It is important to note, however, that we test each batch of NP Thyroid® to ensure that the finished product is within the USP (United States Pharmacopeia) specifications for T4 and T3. We have found no indication that slight variations in odor, color or size of the tablets affect their content, quality or consistency.

    If you have any questions or concerns with NP Thyroid®, please contact us at info@acellapharma.com or (800) 541-4802. Moreover, if you experience a change in your thyroid related symptoms at any time, you should contact your licensed healthcare provider.

    Reply
    • Janie Bowthorpe

      If that is the only answer they are going to give in the face of the large variety of negative results by patients, it appears they will only continue to lose customers based on what people are saying.

      Reply
      • Rita

        I am sure their levels of T3/T4 are tested and are within range. If they are lying about this they could be up for huge class-action lawsuits.

        But do they test them for effectiveness after changes with fillers/binders? I notice they did not say anything about that. So what if they test the thyroid levels in a lab, are they testing them in human subjects? Are these new stinky hard pills dissolving completely in our stomachs? Maybe the thyroid is there but it isn’t getting metabolized in our bodies properly because of fillers/binders/too compressed pills. Maybe we are just pooping them out!

        I noticed since I started chewing up my Nature-throid I feel slightly hyper. Faster pulse, a little lightheaded; both of which indicate I am getting more T3 in my system.

        I still think in all these newly reformulated NDT it is all about binders/fillers and we are just not digesting them properly.

        Reply
  115. Kim

    I just saw this blog post, and it dawned on me that the refill that I picked up earlier this month looks and smells differently. It smells like urine as someone else mentioned. The taste is awful as well. I find it hard to believe nothing has changed?! My 60mg pills look differently and smell differently. That smell is the same as NT when I was taking it. It is the normal smell for the natural thyroid.
    Has anyone received more facts from Acella?
    The lot number for the pills I have is M328A19-3 but she didn’t sound too confident about this.
    I left them a message this morning.

    Reply
  116. Rachel

    My prescription of 60mg matches up M330E 19-2

    Reply
  117. Dawn Kaplan

    I have lot # M331E19-2 (90 mgs)
    M331E19-3 (90 mgs)
    M327E19-1 (15 mgs)
    I called Acella and received a vm. This is frustrating. Do these lot numbers match up with anyone else’s?

    Reply
  118. Bev Smith

    So are you saying that synthetic T4/T3 is now a better option than upping the dose of either NP Thyroid or Naturethroid?

    Reply
    • Alex

      No way to return to synthetics!!! Never ever!!! We all here want to have the NTDs that does work how it did work for years !!

      Reply
    • Rita

      I personally am upping my dose of Nature-throid and chewing up the pills before swallowing before I try synthetics. But if that doesn’t work then I have no choice. I think everyone probably could try upping their doses before giving up on NDT, you will know in 1-2 months if is helping. I am still convinced it is a binder/filler issue since all the reformulations don’t dissolve as easily.

      I will say that since I upped Nature-throid from 1.5 to 2 grains and started chewing the pills I already feel better. It has been a week. More energy, hair loss slowing, sleeping well, losing a little weight. Will get bloodwork in 6 weeks to see how I am doing.

      Reply
  119. Rima

    I just spoke with my pharmacist at Walmart who gave me the lot # M330E19-1 for my latest prescription ACE 60 mg dated 8/22/2019. (from the distributor McKesson in Georgia). The tablets taste awful!!!! I still have a few from the script dated 6/01/2019 so have been taking those, but only have 6 days left. I’ve been on this med for several years, and although I know that I am not optimal, I am way better than before!!!!
    I am dealing with scleroderma, so much going in my body.
    I have left several messages on the customer service line at Acella, sent a comment via the contact page and now just left a message with David Margulis, but no response yet. He did tell my pharmacist today that there have been no changes made in the formulation. I wonder if what has come on the market is a pirated version? There was quite a problem finding NPearlier this year, so maybe someone stepped in to fill the void.

    Reply
  120. Wendy Benton

    I have been taking Acella for quite a few years, I had RAI done on my thyroid in 2006(worst mistake of my life.). Through a mix-up between my pharmacy and my doctor’s office I got a three month supply at the end of July and another three month a week and a half ago.
    I broke a rib just over a week ago and of course had lots of pain, very hard to sleep or lay down. I had to go in to the doctor or they would not renew my thyroid prescription so I asked about my rib, I did not do an X-ray because we have no insurance. Two nights ago I was in terrible pain extremely ill feeling. I woke up about 1 am and felt like an elephant on my chest, my right breast area hurt and my throat area felt as if I swallowed something that stuck in there. I thought it was all related to my fractured rib. I had terrible diarrhea and vomited in the night. Now I believe all these other problems are related to the Acella. It has never, ever tasted this bad, I have always put it under my tongue and it would desolve. Now, to put it under the tongue leaves a horrible after taste that even water will not get rid of. My pharmacy is suppose to call me about the lot numbers and I will call in to the company but I have now paid for two prescriptions of 6 months total and went into the doctor again and had an X-ray because I thought there was some worse problem with my broken rib. This is going to be very expensive and we have no insurance. Very frustrating. I might also add that when I was checked at the doctors, everything seemed fine but my heart was racing and she(the doctor) attributed it to my pain from the rib.

    Reply
    • Alex

      Wendy Benton, what you describe:” …I felt like an elephant on my chest, my right breast area hurt and my throat area felt as if I swallowed something that stuck in there…” I have every time after taking NP Thyroid. That is such an awful pain that I can nothing do and nothing thing… only lie in bed… That’s such an awful pain that I thought already I have the breast cancer at a very late stage… This pain starts in my left breast and spreads in all my upper abdomen. First I couldn’t believe it coms from NP. But if I didn’t take NP for one or two days then I didn’t have this pain…. This is so tragic what happens to us all…

      Reply
      • Wendy Benton

        Alex, I am sorry t hear that. I do not understand what is in the pills that would cause this to happen?

        Reply
  121. DeeCan

    So after reading many of the comments, this is Deja vu all over again. Happened with ERFA in 2015. And I figure it will be the same conclusion in this conversation. No one will know, or find out, EXACTLY what is going on or what happened with our NDT. Just sign me, Extremely Hypothyroid With ZERO Hope. I guess people with Hashimoto’s/hypothyroidism are just expected to crawl through life until we die. Sorry so pessimistic.

    Reply
  122. Terri

    Was stable on both Armour and Naturethroid for about 5 years (have no thyroid due to Graves Disease RAI)… I alternated both products over the years, as both were effective. However got terribly hypo in May 2019 when I started a new bottle of Armour 97.5mg. Have been on a new bottle of Armour at a slightly higher dose and its still not working, even though the batch numbers must be different lots. Switching to Synthroid for now and will work with my integrative doctor to get re-stabilized. Hopefully the manufacturers will get back on track with proper quality control so we can have our preferred medicines back! Just sharing that Armour still isn’t working for me.

    Reply
    • Janie Bowthorpe

      FYI: no one is going to do well on only 97.5mg. That is underdosing. We have to be optimal, which puts the free T3 at the top part of the range and free T4 midrange.

      Reply
      • Terri

        Thanks Janie– for years at 97.5 my TSH was in the 2.5 range and the other numbers were OK and I felt good. I really appreciate all that you do and thank you so much!

        Reply
  123. Catherine

    I started NP thyroid April 2019. I am new to NDT. However, I suffered greatly when increased from 30 mg pills to 60 mg pills in June. I suffered an entire weekend in bed with chills and muscle fatigue. I also broke a toe. My entire body went down. I could barely function and could not even force myself. (Which is what I usually do)

    I knew it was a bad batch immediately as I once suffered the same on Synthroid several years ago when getting a bad batch. I contacted Acella and put in a complaint. They never got back to me afterwards or replaced the bad batch.

    However, I will not go near the 60 mg pills since that day. I had my doctor prescribe all my pills as 30g pills for 90 days and have since then increased from 2 grains to 3 grains. However, I soon start a new batch of 30’s and so who knows.

    Maybe the change started with the 60’s? I wont touch them as i was far sicker than I have ever been even when not medicated at all. I know when my thyroid goes down and that is exactly what happened on the 60 mg pills.

    This news is very discouraging as I have suffered greatly and worked hard to get to the 3 grain dose I am on now. I have half a thyroid due to thyroid cancer and am a single mother of two small children who works full time. I must function whether I like it or not. I am allergic to Armour and levothyroxine and suffered horrible joint pain and damaged knees on Synthroid and so where do I go from here?

    Reply
    • Janie Bowthorpe

      Next potential step: T4/T3 and geting optimal, or the over the counter natural thyroid supplements like Thyrogold and etc and getting optimal. They are both seemingly working well for patients if optimal.

      Reply
      • Marianne

        I was optimal and in complete remission in October 2018, on Naturethroid (32.5 tabs x 4 daily)…I wanted to see if i could feel even better, so i stopped that and tried thyroid gold beginning jan 8, 2019. First the pills are too big and i found one was not enough but two sent me hyper for sure… But worse, my follow up labs showed I had moved just barely out of remission! Was it the added iodine? IDK. WP became available, but I had already upset the apple cart and my TPO antibodies have continued to rise.

        Reply
  124. karen l ivey

    Found a dr to prescribe ndt, I chose np thyroid. I am no where near optimal and we are raising. I was on day 6 of a an increase feeling better and then it felt like i had hit a brick wall. Heart rate starts dropping, constipated again fatigue is returning, in a matter of days I could feel it. I messaged the dr and said something is the matter and I dont know what. Then I saw the facebook post about np thyroid. I had gotten my prescription a week early and mixed the bottles, sure enough i still had 5 old tablets left.

    Reply
  125. Tracy

    I just talked with Steve. He informed me that he is not aware of any formula changes. However, he said that he couldn’t confirm that there were no formula changes. 🤔 My last refill was half good half bad. My new refill is all bad. Smells like cat piss! It is also has more shine, is thicker and lighter in color. It also takes much longer to dissolve under my tongue. My personal belief is that there was a formulation change. Ugh!!!!

    Reply
    • Emily

      Tracy, do you have a phone number for Steve?

      Reply
    • Lynn

      I had taken Naturethroid for years without issue starting at 1/4 grain and increasing to one grain. January 2019 thru May 2019 I was switched to WP without being told or noticing. In June 2019 they said they got Naturethroid back and could switch me back so I did. Mid June I started losing a huge amount of hair, fatigue, joint pain and itchy. My gyno was insisting it was low estrogen until I read about the problems with Naturethroid and got her to switch me to NP if I agreed to take estrogen. After two weeks, the hair loss stopped and at the month mark my labs were better but my estrogen is lower than before. I assumed that all was good because of the hair but now the fatigue is getting worse as is the joint pain which led me to research NP and discover it is bad now too. My first month of NP was 4 x 15 mg and latest is 1 x 60 mg. Comparing the two, the 60 mg smells horrible. Maybe I got a good then bad batch. Could my hair loss have stopped but the other symptoms gotten worse including burning feeling in muscles? I was thinking that maybe something else is wrong with me. This is like a puzzle. Since I am barely functioning I am going to try the two days I have left of the old. I also have Naturethroid from 2013. Would I really screw myself up taking that? It has been so nice to have my remaining hair staying on my head that I don’t know what to do.

      Reply
  126. Emily

    Thank you, Debby, for keeping us apprised of your conversations with Acella. I have contacted them twice via their website and have left a message at the number Janie has posted. I have not heard back from them yet I so will try the number that you provided for David. I’m not as concerned about color changes, but the larger size and strong ammonia smell (if you have a cat litter box in your home, you’ll recognize the smell) of the new batch has me very concerned about the strength and purity of the new tablets. The last time I encountered med problems (with Mylan’s generic synthetic T4) and got no response from the manufacturer, I reported the problem to the FDA and was surprised at how quickly a Mylan representative contacted me. We may have to do the same with NP if we don’t get satisfaction from Acella.

    Reply
    • Anby

      The FDA was notified. It’s the policy that when a patient reports issues.

      Reply
  127. Becky

    I just got off the phone with Steve at Acella. I had filled out their contact form last night – and they actually called me. He was very concerned, spent a long time with me and took down a very thorough description of my situation. He’s going to call Walgreens for my lot number and also sending me an envelope to send them some of the new pills to test. He assured me they have not changed the formula or processing method but they’re trying to get to the bottom of this. I’m guessing maybe it’s an issue with the source? I got a mix of the old and new pills in my last 90 day refill. I immediately noticed a difference in color and taste, but the pharmacist assured me it was the same medicine. After a couple weeks of taking a mixture of the two, I noticed worsening hypo symptoms – and it just so happened that I had bloodwork at that time. My TSH went from 0.4 to 1.9 and my free T3 was down to 0.8 – below normal. With just two weeks of a mixture of the old and new pills. When I realized what was going on, I divided out the pills so I’m just taking the old ones now and already feel better after just 3 days. My problem is I absolutely cannot take synthetic – it’s not a matter of preference – I ended up in the ER back in the winter when a new endo insisted I try synthetic. I had done fine on Armour for 15 years until the new formulation – which is why I switched to NP about 3 years ago. Now I don’t know what I’ll do if they can’t get the NP right. Thanks everyone for your stories. I was relieved to know it wasn’t just me. Although not relieved to find out it’s worse than just one bad batch. I encourage you to contact Acella. If they know how many people are affected, hopefully they’ll figure out a resolution.

    Reply
    • Emily

      Debby, did Steve give you his contact phone number or an e-mail address to contact him directly? I contacted them several days ago through both the Acella and NP Thyroid websites and have yet to hear from anyone. 🙁

      Reply
    • Kim

      Becky,
      I see that you say you cannot use synthetic, have you tried Tironsint? If so what were your symptoms? I tried Tirosint and have had no issues with it, but the other synthetics make me sick too.

      Reply
      • Janie Bowthorpe

        But…even tho Tirosint works better than the other T4’s, it appears, it is still problematic to force the body to live for conversion to T3 alone. We all seem to need direct T3, which is also how a healthy thyroid behaves–producing some direct T3.

        Reply
      • Becky

        Kim,
        Actually, yes, I tried Tirosint. In fact, I was doing fair on a levo/cytomel combo for about a month when I tried Tirosint which triggered the reaction. Itching and extreme anxiety, insomnia, fever, hyper symptoms. After that, I couldn’t even tolerate the smallest dose of levo in any form, including synthroid brand. A compounding pharmacist told me a lot of people do better on compounded t4/t3 because it doesn’t have the fillers. So I may cautiously try that if I have to. And may give Armour another try. I have appt with new Dr next week so I’m hoping she has suggestions. I feel like I might have adrenal and Rt3 issues that need to be addressed too.

        Reply
  128. Debbie T.

    back again. well, David called back to say that AvKare repackages in smaller quantities, that ONLY Acella manufactures NP and that……”nothing has changed.” 🤔 He also said if anyone has questions to call, so here is his direct phone #: 678-325-5306

    Reply
  129. Debbie T.

    okay folks…..so I just got a call back from David Margulis, Sr. Manager of Customer Service. I told him about the two different images on the GoodRx website and that one of them states it is “manufactured by AvKARE, Inc.”. He seemed very concerned and baffled, and that Acella was the ONLY manufacturer of NP. He said he would look into it and call me back. I also mentioned that I belong to several thyroid support groups and there has been a lot of discussion about new Rx fills looking/tasting/smelling/working differently, and I’d appreciate any information he can send my way. I will update again when I hear from him. Stay tuned…..

    Reply
    • housemaid

      I am confused because when I look at the Good Rx website, I see photos of the front and back of the NP thyroid pills and they look the same as usual. I also see nothing about it being manufactured by AvKARE. Maybe Good Rx uses different photos for different parts of the country? My recent 3 month refill of NP was a good batch. I don’t think I would just take more of a batch that smells like cat piss, hoping that might make it work. It could be adulterated and dangerous for all I know.

      Reply
  130. Tammy

    Acella has a contact us link on their corporate web page. I suggest everyone unhappy with the new formula use it. They need to hear from us.Quote from their mission statement

    We are committed to developing, manufacturing, and distributing products that meet the highest quality standards through compliance with all applicable regulatory requirements.
    Ha

    Reply
  131. kim

    been on Np thyroid for 2 years take 120mg x2 plus 60 so 300 total needed refill about 2 months ago was told 120 was on backorder so they would give me 90×4 plus 1- 30. mind you my labs were great finally and I was losing some pounds I took the pills as usual and the taste was horrible I almost threw up tasted like hoe cat pee smells if that makes sense well since then I have been so fatigue I bareley make it threw the day and my pain is all back weight gain and losing hair so I guess I may need to try something

    Reply
  132. Victoria Connolly

    My 60 mg tabs, filled yesterday are different than ones filled in June. Contrary to what others are saying the old ones did smell, the new ones shockingly have no odor. The new ones are greyer, mor mottled and larger than the old supply.I have just become optimal in past couple months. So worried now.

    Reply
  133. Cincolo

    I never put 2 and 2 together. I assumed my starting to nod off at 9 p.m. was just because I needed to increase my dose. I did increase my dose, but even then I’m still more fatigued than usual. I now believe my 6-8 lb weight gain the last 2 months is also from this. This is different than what Armour and Naturethroid changed. I was on both of those and saw the same signs-pills were harder with less porcine smell. These new pills have a really strong smell, and I think they actually dissolve faster. Maybe they changed a filler or took one out all together…. Regardless, I wish there was a law preventing them from changing medications without publishing exactly what they modify. This was the last option for many of us that have done well on NDT (since Armour and Naturethroid changed their formulas and many of us didn’t do well on the new formulas).

    Reply
  134. Betty White

    I don’t understand the above article that says acella is looking into the lot numbers that are not working for some. Since all the new ones look the same shouldn’t all of them not work?

    Reply
    • Janie Bowthorpe

      The amount of new “batches” out there may have different lot numbers. We don’t have all the answers, but at least they are willing to look into the batches/lot numbers that represent the changed tablets.

      Reply
    • Judy

      Hi. I just called Acella pharmaceutical. Left message gave them the lot number for my refill I just picked up this morning at cvs
      Honestly. Someone mentioned it smells like a litter box That is the truth. Smells like dry urine And the taste still a bit sweet. But horrible I hope that giving them the lot numbers. They can get to the bottom of what’s going on

      Thanks to

      Reply
  135. Lisa

    I chew my NDT tablet so I have not noticed any change in my symptoms. I noticed earlier this year they had a more porkier smell but they till still tasted sweet when I chewed them. They smell really bad now but they don’t taste bad when I chew them and like I said above my symptoms have not worsened.

    Reply
  136. Renee

    I was a loyal WP thyroid patient, but switched to NP thyroid after WP became unavailable. I tried Naturethroid before I went over to NP, but I got really sick on it. It took a lot of fiddling with the NP dosage and making dietary changes and getting LOTS of blood work, but I finally found a good dosage at 120 mg. I’ve been doing great for many months! But, the last ten days or so I’ve noticed a lot of fatigue that I didn’t have before. I find myself yawning in the middle of the day and I never do that. Now I’ve also noticed that old feeling I used to get in my arms. One of my weird symptoms is that my upper arms get so tired that I have to rest them in the middle of blow drying my hair. My eyes are super dry and I NEVER had that problem before. I also find that I am having anxiety again. The kind that hits me out of nowhere and for no reason. I got a new bottle of NP a few weeks ago. My pharmacist told me that they couldn’t get the 120 mg tablets, so they substituted with 60 mg tablets. So I take two pills instead of just the one. My pills have always had a bad odor so I cannot attest to the change in smell. They smell just as bad to me now as they always did. But, after reading all these comments, I guess it’s time to call the doctor yet once again for blood work yet once again so I can mess with the dosage yet once again. I SO wish I could get off this ride. It depresses the h*ll out of me to know that I am tethered to thyroid meds for the rest of my life. I hate being at the mercy of these companies.

    Reply
    • Janie Bowthorpe

      Hi. It is very common to start feeling good on to low doses of NDT. But it eventually backfires, as the total dose is not enough for one’s daily needs over time.

      I’m saying this because it’s very uncommon for two grains to be enough. That’s why it was very important to have watched the free T3 and free T4 and have gotten optimal. An optimal dose turns out to be enough for one’s daily needs, so it doesn’t backfire.

      Reply
    • Ally

      Agree, Renee! I am also tired of chasing down Rx when primary pharm is out of stock and now this latest batch is making me physically ill (gag to get down, needed a 2 hour afternoon nap, headache, nausea, diarrhea, and heaving sweating episode). I am currently researching holistic protocols to see if I can find a way to heal the Hashimoto/hypothy – many day “not possible” but cells are continually rebuilding. I am currently considering 3 diff protocols; I want off this insane ride.

      Reply
      • Janie Bowthorpe

        That is horribly profound that after taking the latest batch, you needed a 2 hour afternoon nap, had a headache, nausea, diarrhea, and heaving sweating episode. That is simply BIZARRE.

        Reply
      • Judy

        Ally, when the big recall happened almost a year ago, I concluded the same, that I just have to heal so that I don’t need medication anymore. What protocols have you found that could be healing? It’s very very scary to think that we are dependent on a medication for the rest of our lives and that the medication’s availability is highly unpredictable. The stress of all that is enough to make anyone very sick, so the stress of just trying to get the meds is making us sicker, which is really insane, since the medication is supposed to be helping! Like you said, the cells are always rebuilding. Our bodies are always trying to achieve balance.

        Reply
    • Renee

      Hi Everyone,
      I just called my pharmacy. They refilled my NP thyroid script a few weeks ago. As I stated above in my previous comment, they were unable to provide me with the 120 mg pill, so they had to give me 60 mg, meaning I have to take two of them instead of one.
      They gave me a 90 day refill. I asked for the lot number. I was told that they used FOUR different lot numbers and mixed them all together in one bottle. I asked if they could tell me how many of each lot # I was given and they said they could not.
      In one bottle, I was given lot # M330L18-1, #M330B19-2, #M330C19-5 and #M330C19-3. He assured me this is a common practice to mix several or many lot numbers together. Does anyone have any or all of these lot numbers too, and if so, is anyone having issues?

      Reply
  137. Stephanie Gundrum

    Sooo……I thought I was being paranoid or just a complainer. Just made a move from Illinois to Texas in June and got my refill in May (120 mg in the a.m. NP). I too thought they tasted and smelled weird and seemed fatter. I was not optimal before, but definitely feel like I just can’t get going. I just chalked it up to the huge move and getting acclimated. I could basically sleep at any time of the day, except late evening- figures, my hair has gotten more brittle and just can not get motivated to get on my good routine of healthy nutrition again.
    Guess I will be making a call. But now I need to find a new doctor in Texas to work with me.

    Reply
    • Janie Bowthorpe

      Yep, not being optimal means there is going to be a return of hypothyroid symptoms. But…we are now pretty sure we are seeing even worse hypothyroid symptoms for those on NP and who weren’t optimal. i.e. worse hypothyroid symptoms on top of the ones that were destined to come back anyway.

      Reply
      • Stephanie Gundrum

        I am considering ordering Thyro-Gold again. I was using it a few years ago and it helped symptoms but was hard to get the dosage just right.

        Reply
    • Laralee

      Where in Texas? I know a good doctor in San Antonio.

      Reply
  138. Rita

    I have a question. So all of our NDT have been reformulated now apparently, and all don’t seem to be as effective.

    Has anyone seen any real numbers on whether taking higher doses and crushing the pills of the newer versions has worked? Maybe people expect their old dose to work so rather than raise it they just switch? Or they have doctors who won’t raise the dose because they only look at TSH and not the frees, so they blame the pills?

    Could this be as simple as just too many fillers/bad fillers and increasing doses, crushing pills would be the fix?

    I ask this because both the old Nature-thyroid and NP were easily dissolved under the tongue and both the new version aren’t.

    I am testing my theory with Nature-throid, will report my results in two months. Increased dose, crushing the pills. Keeping my fingers crossed, but several days in I feel great.

    Reply
  139. Deanna Walden

    After months of going from pharmacy to pharmacy searching for my Np, I was delighted when CVS called and said they got it in last month. I started them and the taste reminds me of what cat pee must taste like!! After a few weeks I began being tired and having body aches, did not relate this to the NP because I recently had surgery. After I read this it all made sense. I have read about Throvanz? It is made from cows and doesn’t need a prescription has anyone had any luck with this?

    Reply
  140. Delaena Ganske

    I am not on NP but was on Armour and when it changed, my symptoms came back full on. Then I switched to Naturethyroid and still fee ok but haven’t checked recently. What is the alternative if all of our options go bad?? Will we be forced to go to Synthroid or equivalent?
    Thanks for the notice on this

    Reply
  141. Rachel

    Have been on NP Thyroid for years after the debacle with Armour and then Erfa. After switching Endos ( the last 2 wanted to downgrade me from 90 as my TSH was too low but tried 75 for 2 months just to prove a point to them and felt absolutely terrible. Now with new fabulous Endo I am on 60mg twice a day and am optimal. Just received 3 months supply from Express Scripts but they are definitely different from previous tablets in smell and taste. They don’t dissolve easily when I sublingual and they don’t have the same sweet taste ( believe it or not I just assume that my pig pills have a stinky smell and taste and I don’t mind- it is after all a pig pill :).They are bigger and grey in colour and the LOT number is M330E192 and have AP on one side and 330 on the other
    I don’t want to even experiment with this new lot as have just started to feel SO much better on higher dose and remember how much I struggled under the Armour change.. Express Scripts suggested going to local pharmacy to see if they can override the prescription and give me a new order for 30 days but they can’t guarantee its not from the same LOT.
    Will try this and see if a new order might be like the old ones otherwise I will have to raid my piggy bank and fork out for compounded NDT.

    Does this LOT number resonate with anyone who is currently struggling on the newer NP?
    .

    Reply
    • Cincolo

      I can’t find my lot number on my medication from Sam’s Club. There is no expiration date on my bottle either. Goodrx says: Bottles and vials-Drug bottles will often have the lot number printed next to the expiration date, either by the barcode (1) or underneath the dosing instructions (2).

      Reply
      • Cincolo

        Sam’s Club says they don’t keep a record of the lot numbers! What if there was a recall??? I wonder if this pharmacist knew what she was talking about.

        Reply
  142. Andrea

    Just picked up new prescription NP Thyroid. Can’t tell by looking at tabs, may need magnifying glass for that. But the smell is definitely bad, definitely noticeable. I won’t start these new ones until next week. Having labs done this week however, and meeting with doctor on September 11th to discuss all this. Will continue to update.

    Reply
  143. Lily Richardson

    I really don’t know where to turn. I am in the process of changing doctors. Had 1st Appointment with the new doctor 2 weeks ago. He raised my dose of NP thyroid (from 30mg+15mg) to ONE 60mg pill of NP thyroid. (plus Cytomel) I had a very sickening reaction after just 3 days of taking the new NP 60mg pills, and have been sick in bed with flu-like symptoms for over 5 days. I had not dumped my old doctor yet, so have gone back to taking the 30mg + 15 mg. dose and have added another 15mg pill of NP thyroid (until it runs out, since I am now double dosing the 15mg pill.) Long story short — the new doctor mentioned his wife takes WP Thyroid – “because of less fillers.” I am wondering if I should ask him to prescribe WP for me now? I started on Synthroid perhaps 10 years ago, then had good luck with Armour, then it was not available, so have been on NP Thyroid for perhaps 4 years or so. Now this has happened. Where can I find info about the status of WP Thyroid? (And if it has had problems like the others?) I think that is perhaps the direction I should try to go. I have really been sick with flu-like symptoms and am really afraid to take any more NP Thyroid 60mg. pills. I cannot believe the NDT drug makers screw around with the ingredients. You just know if this was happening with a heart medication, it would make it on the evening news.

    Reply
  144. Ellen

    Since taking the new smelly NP pills, my feet ache so much, my fatigue is heightened, my eyes are dry, and I feel out of it most of the day. Nothing else has changed. With a new smell and new look, it is quite obvious they screwed this pill up. I will report the batch number to Acella and will stop taking it.

    Reply
  145. Tammy

    I take NP Thyroid twice a day, 90 in am, 60 in early afternoon. Both were refilled at the same and both smell and taste horrible.
    I haven’t noticed any changes yet, I’m due for labs in a few weeks. Fingers crossed.
    Sad they changed but glad it wasn’t just my imagination.

    Reply
  146. Jeanette

    I was switched to NP thyroid when it was impossible to get WP Thyroid anymore last fall. It has been a downhill slide since then and worse with each refill. Fatigue, always cold, hair shedding alot and a 15 lb weight gain. My labs aren’t terrible but not optimal. I also take T3 because I had an issue with high RT3. Feel relieved to learn this may be an issue with the product. Armour stopped working for me when they did their reformulation. So I actually may ask for synthroid.

    Reply
    • Janie Bowthorpe

      Instead of just “asking for Synthroid”, ask for BOTH T4 and T3 as separate medications. And Tirosint may be a better T4 than Synthroid to add to T3.

      Reply
  147. Donna

    So if I was taking 120 NP just started in May 2019 how would that convert to synthetic T4 T3. I think my first 30 tabs were good ones but the next were the the spotted stinky ones. Would rather get a head of these before the damage starts.

    Reply
  148. Laurie

    I switched from Synthroid to NatureThroid because I wanted something natural and not synthetic. My labs became wonky and all of my hypo symptoms returned. So, I took the dive and switched to a compounded version. I feel 100% better now and will never go back to anything else. My advise is to find a trustworthy compounding pharmacy. Yes, it is much more expensive, but know that your dr can precisely tweak your script as your body needs in order to stay optimal! There is nothing more important than your health!

    Reply
    • Janie Bowthorpe

      Most compounding pharmacies are simply compounding the two synthetics, by the way.

      Reply
      • Cincolo

        Well that’s good to know! I assumed they’d add the other NDT components also. I will confirm with the pharmacy I’m looking into to see if they do this. If not, it’s likely cheaper to just buy the 2 synthetics.

        Reply
      • Martin Loiselle

        Our pharmacy does not add the synthetics. We use only natural desiccated thyroid. We would not be able to provide the two synthetics combined if we received a prescription for natural desiccated thyroid – we would only provide what is on the prescription. I am glad you are feeling better, Laurie!

        Reply
        • Judy

          Martin, how are you able to get NDT? My pharmacy of many years has been unable to get NDT since the recall happened almost a year ago. I wish I knew of a compounding pharmacy to use. Do you use any fillers?

          Reply
        • Cincolo

          Martin, can you give us your pharmacy name? I guess it would only be beneficial if they did mail order though.

          Reply
          • TD

            @Judy, @Cincolo:

            His name has a hyperlink, if you click it goes to https://www.woodlandhillspharmacy.com/ which is in CA.

            I went there and found a blog post from a few days ago that answers your question, @Judy. It is “USP Thyroid” – that’s the same ingredient that all of the manufacturers use for NDT. They just use different formulations of inactive ingredients, which can effect how it is absorbed, etc.

            I have no affiliation with woodlandhills pharmacy or Martin, but here is the post I’m referencing: https://www.woodlandhillspharmacy.com/acella-np-thyroid/

            Hope that helps. I’m just as frustrated as everyone…

  149. Gin

    I was on nature throid for a few years and felt great and then slowly started to get hypo symptoms. Then switched to NP over a year ago but it started giving me heart palpitations for almost a year even with different dosages. Tried to get on WP but can’t find in stock so I am back to nature throid. Ugh

    Reply
  150. Terry

    Mine smell like cat pee
    Have been having trouble breathing since starting new refill of 90

    Reply
    • Janie Bowthorpe

      90 mg wouldn’t have been optimal at all. It underdoses everyone. But if the tablets are messed up, it won’t help to raise them, we think. It’s better to go to both synthetic T4 and synthetic T4 and get optimal.

      Reply
      • Terry

        I was taking 105 (90 +15) the old pills but after 10 weeks I started having really high pulse and blood pressure. So went down to 90 and it all went away. It scared the hell out of me.
        I have done really good on 90 it’s been about 5 weeks now my ft3 on the 105 was 3.0
        So I should just keep increasing and keep have horrible pulse and blood pressure to get to the upper ft3 ?

        Reply
        • Janie Bowthorpe

          If you had all that on the old and good pill, which we know works great compared to the new one, you may have just gotten that high pulse and BP from staying on too low a dose too long. We don’t stay on those lower doses much longer than two weeks without raising. We then slow down in the 2-3 grain area to see how close we are to optimal…or not.

          Reply
  151. Samantha

    I DONT FEEL CRAZY! I kept asking around and around about changes in NP and no one said they saw a change. I noticed a change when I picked up my batch back in early May. I told my doctor all of the sudden something changed. My heart palps we’re back. My body wasn’t tolerating the medication like I was. It was almost IMMEDIATE. I was 9 months TT and before that was doing fairly well on it!! Then boom, I even bought 2 more bottles and the same thing. I didn’t have the reaction on the newly formulated WP (which isn’t great) the doctor said it must be my body not needing t3 anymore. Needless to say it’s been a hellish 4 months being put back on synthetics. Now I’ll tell my doctor and try armour! Wish I trusted my gut!! I knew something had changed.

    Reply
  152. Jeanne

    I have not had a thyroid since 1998… I was on Armour for years with no problems, then ERFA until their issues, then Naturethroid – no problems, felt great, just couldn’t get it. I switched to NP in May of this year.. first month fine. Second refill and a month and a half later.. I am terribly unwell. I was hospitalized for another issue and was thinking I was feeling bad from that. NOT — after reading here about Acella, as as test I took Naturethroid today… NO PROBLEMS OR FEELING TERRIBLE. The only way I can describe what it was doing to me was how I felt when years ago I tried synthyroid — extremely fatigued to the point of non-functioning, like I was being “force fed” something terrible, or poisoned. I am guess I am hypo and/or my body isn’t converting it. Have full thyroid panel done Thurs so I’ll see where I am, but even if my numbers are okay… my body DOESN’T like NP. I am on 2.5 grains (divided dose) per day.

    Fortunately I have the lot #’s. But now I am in a quandry as to WHAT am I going to take. 🙁

    Reply
  153. Dawn Kaplan

    I just received my replacement rx from Express Scripts. It’s identical to the pills they sent me for my last refill. This is aggravating.

    Reply
  154. Rae

    Switched to NP Acella in May based on some positive reviews from this site and elsewhere, and immediately felt horrible. Tired + weird feeling, which lead to anxiety and basically a return of debilitating fatigue.

    After two weeks of that terribleness I switched to Armor, have to pay out of pocket, but I will never take NP again. Horrible.

    Reply
  155. Jenell

    I was finally feeling better, being active, but since I got my refill I’m literally feeling, extremely fatigued again, and depressed.

    Reply
  156. Mr Anybody

    I was on Naturethroid two years ago this month and felt good.

    Then came the shortage and I landed on NP, things have gone down hill since.

    I haven’t worked in a year and it’s very difficult for me to walk now.

    Reply
  157. Michelle Sarchiapone

    Anyone have any suggestions on how to get the old formulation of NP?? Could I call pharmacies??

    Reply
  158. Janeen

    I switched from Naturethroid to NP when it became scarce. I have never had an issue on NP nor seen a change in the pill itself. Had it always smelled? Yep! I take 2 grains in the morning and 3 in the afternoon. It almost seems like going back to synthetic, even though I hate the thought, is going to happen eventually. I wonder if there is a doc out there that will prescribe me 45mgs if T3 without having a tantrum. 😂

    Reply
  159. Robyn

    My Dr switched me to NP in early May and raised my dose, and I have not felt any better at all. I am fatigued all the time. My dr chalked it up to not sleeping well.

    I was not optimal beforehand, but wa a looking forward to feeling better on this recommended NDT

    Reply
    • Bonnie Rasmussen

      Hello Janie,

      I am very concerned about the changes made to NP. Nature did the same thing and I got so hypo it took forever to recover from that. I read the 5 options you posted on this page. Would option 6 be to take a compounded natural desiccated tablet? I have never been to a compounding pharmacy. Are compounded pharmacies also experiencing shortages? If compounded medications have less fillers then would this be a good option? Does it matter which compounded pharmacy I use?

      Reply
      • Janie Bowthorpe

        It’s possible if they actually have a source of NDT powder (many don’t) and if it’s a good source…

        Reply
      • Martin Loiselle

        Our compounding pharmacy has NDT powder in stock and we rarely run out. We provide it in capsules with one filler and no other additives. It does need to have one filler but we have options and can even look into alternative fillers sometimes at the request of the patient.

        Reply
  160. Linda Dorcely

    I am on 65mg Nature-throid. I felt great for the longest time. Wondering why I started feeling like crap 6 to 8 months ago. I started researching online and thru sites like this found out I am not the only one. Just thought I would write a post for anyone else who may be searching for answers. You are not the only one. Apparently, Nature-throid has changed their formula. My achy body has returned, by 4:30pm I am dead tired, I feel anxious or neurotic at times, and unusually warm. Typically, I am the one that is cold but now it seems I’m hotter than everyone else. I am going to ask my doctor to switch me to synthetics until whatever is going on with NDTs settles down.

    Reply
    • Janie Bowthorpe

      Hi Linda. The problem is that at first, nearly anyone is going to feel good on a too-low dose of NDT. 65 mg is definitely too low. It’s simply a starting dose. But eventually, being too low, which is suppressing more than replacing, backfires. You are most likely experiencing that backfire with a return of hypo, not just that it’s changed. But switching to synthetic T4 with synthetic T3 is a good thing. BUT this time, get optimal!! Optimal puts the free T3 at the top part of the range, and free T4 midrange. Both.

      And you probably need to test your four iron labs. As low as you’ve been, there’s a chance they might be at inadequate levels due to still being hypothyroid. https://stopthethyroidmadness.com/iron

      Also consider doing what’s on this page, since adrenals become stressed from being too low, as well: https://stopthethyroidmadness.com/adrenal-info

      Reply
      • Rita

        Linda, have you tried raising your dose of Nature-throid? I was also happily on 65 mg for over 10 years (crazy,right?) and since Jan 2017 had problems. I finally got a doctor who ignores TSH and pays attention to free T4,T3 and started raising my dose. I had just switched to NP for 3 months since I read here it was better, but now am back on Naturethroid. Trying 130 mg (2 grains) now. Will see how my bloodwork is in 2 months. The pills are hard so I am chewing them up before swallowing them. I also get labs 24 hrs after taking my pill, another change. If my numbers don’t get better on 2-3 grains I will try Armour. But so expensive!

        Has anyone had success with Naturethroid after the reformulation by both raising their dose and chewing the pills? The original Naturethroid was softer and dissolved easily. Maybe if it is chewed up it will
        work better as reported about Armour? Worth a shot since NP is suspect now.

        I just can’t take the new NP, it smells and tastes toxic.

        Reply
        • Cincolo

          Two years ago when Naturethroid changed their formula, I tried chewing the pills for a couple weeks to see if there was any improvement. It did not make any difference for me.

          Reply
    • Renee

      My doctor switched me to NP thyroid about 6 months ago. I had been taking Nature Throid previously. I felt so much better after starting NP. I was finally starting to lose a little weight and I had energy for the first time in a long time. He prescribes a 60 day supply for me. My first bottle of it was amazing! I had even forgotten how crappy I had been feeling until I picked up my refill. The smell was horrendous! But, I just figured that maybe I just wasn’t used to the smell of this brand. After I started taking my new refill I immediately began feeling like crap again. Literally every symptom I had ever experienced came right back. It took me a little while to suspect that it was Np. I didn’t understand how I could have been feeling so good and then going to feeling like I was going to die! During this time I started searching online and on Facebook to see of anyone else was experiencing this and I couldn’t find anything. This would have been sometime around may/june I believe. I will say that once I finished that bottle and started another new refill I did get better again. Hopefully it was just a bad batch and not a permanent change to the medication!

      Reply
      • Dee

        Renee, I also experienced my bad batch in about May or June–you have given me hope that perhaps the next refill will be back to normal. I am so glad you are feeling better on the new refill! I really like this company, and hope they have not permanently changed the formula.

        Reply
        • Hadassah

          I too am very hopeful that it’s just a hiccup . I love NP Thyroid It works so well for me and for many others . I feel very confident that Janie who doses with NP thyroid too will help us through this .
          Thank You Janie For All The Hard Work You Do For Us Behind The Scenes And Forefront .
          Janie Your One Amazing Lady …

          Reply
  161. Jamie

    On August 1, I switched from Synthroid (50mcg) to NP Thyroid (1 grain). I am also taking 75mcg Liothyronine. By August 7, I started feeling fatigued. By August 12, all of my old hypo symptoms had returned: fatigue, weakness, anxiety, confusion and severe heart palpitations. Since August 1, I’ve gained between 5-10 pounds and my hair is falling out again. I stopped the NP Thyroid and restarted Synthroid, and am hoping get relief soon. I feel for everyone affected by this.

    Reply
    • Thy Roid

      This is exactly what has been happening to me. I’m back on Levo+T3 but everything is reduced per my doctor. Still not feeling great… I hope you do better.

      Reply
      • Janie Bowthorpe

        You need a better doctor…

        Reply
        • Thy Roid

          I know it.

          I found one doctor somewhat nearby in the recommended list but he’s an endo also and doesn’t come with much in the way of testimonials. Do you think I would be better off working virtually with Dr. Bouc? I don’t even know what that means.

          Reply
          • Nicole

            I just left a message for Acella with my batch number. I switched to NP from NT this Spring and felt so much better as also indicated in my labs. I picked up my new 90 day supply on 8/8 and have been suffering from extreme fatigue, headaches, heart palpitations and now a case of plantar fascitis. I got my labs yesterday and my TSH went up 2 points! So there’s definitely something up here. Although I haven’t noticed any change in the smell or appearance. They always had a pungent taste to me compared to NT

      • Jamie

        Hope you start feeling better soon!

        Reply
  162. Sarah

    Oh no! I just switched to NP Thyroid after my health deteriorated on Naturethroid. NP made me feel alive again. I still have a decent number of 330 tablets left but I’m SO SICK OF THIS.

    I have a good compounding pharmacy that can do compounded NDT (though expensive). Is this a viable alternative, or are their sources compromised too?

    Reply
    • Martin Loiselle

      No, our pharmacy has NDT in stock and we make it in capsules. The sources of NDT are not really compromised – we usually are able to obtain it even when manufacturers are experiencing shortages.

      Reply
      • Janie Bowthorpe

        Martin, after having so many pharmaceuticals (I know you are a pharmacy) state that they “changed nothing”, how can patients trust that your NDT source is “not really compromised”? That doesn’t sound too promising. What would help is to hear from patients who outright use nothing but your product and have optimal results on it and which has lasted and not gone away. Too may patients say they feel good, but they are underdosed, and it’s doomed to backfire. Others say they feel good, and it’s more about the excess adrenaline from being underdosed.

        What will be INTERESTING about this is…

        1) if it’s truly not “compromised”
        2) if only ONE filler is there
        3) if I get to hear from real live people who USE your compounded product and produce the free T3 result and free T4 results, not just “say” they are going “great”
        4)…then that “might” imply it’s the fillers and binders in the prescription brands that are the biggest problem.

        Reply
    • Christi

      I picked up my new Rx of NP 7/13/19. I take 60mg every morning. My numbers up to that point had been optimal. About 2 weeks after starting the new batch my hair started falling out at an insanely high rate. Like wads full after showering and I could feel it falling out throughout the day.
      I started to notice that I was getting the jitters but I’m so new to the world of thyroid meds that I was looking for other things that could be causing it. The jitters have only continued to get worse, but I’ve also had extreme exhaustion, extreme muscle fatigue, strangely no appetite, sensitivity to heat ( which is not normal for me at all ), my vision seems to have gotten much worse in a quick amount of time, along with nausea and a few other symptoms. I actually felt so bad yesterday morning that I drove myself to the ER thinking there was something more wrong. They ran blood work and my TSH came back really low which I’m told means I’m over medicated.
      But I’m consistently taking the same dose every day so that just proves that there is an issue with this batch in my opinion. I’ve been taking NP since the end of March and haven’t had any issues with pooling so I don’t know why that would start now?
      Last Monday I stopped taking NP after reading some comments on a Facebook group about the batch that had gone out. I guess unfortunately there hasn’t been enough time for it to get out of my system as I lay here in bed at 7:43 AM with no intentions of getting up anytime soon…

      Reply
  163. Rickey

    I am on 180 mg of NP Thyroid daily. Have been on it for a couple of years. It works great for me. Dr. has lowered my dose a couple times. I just had labs. TSH <.01; Free T4 1.4; Free T3 9.1 He will probably lower my dose down a little when I see him Wednesday. I haven't noticed any of the changes (smell, size, etc.) in my meds. I get them mail order from Optum RX. I did receive an email today from them saying that they are unable to fulfill my order because the medication is out of stock. Looks like I will have to find it elsewhere or change to something else. Too bad, cause it was working for me.

    Reply
  164. Rima

    Thank you for this!!! I just picked up my new prescription and took my first pill this morning at 6:30, in my sleepy state, I chewed it like always and YUCK!!!! I couldn’t even get rid of the taste by drinking water.

    Before reading your email, I had already left a message at the Acella customer service line. Will report what they say. I wonder if they are getting this new stuff from China?

    Reply
    • Cincolo

      Oh I hope not! I wouldn’t trust any food related items from China; they don’t have the highest standards. Plus with our tariffs now, they would probably like to stick it to us any way they can.

      Reply
  165. Donna Frank

    I went to a functional dr last January and she started me on Naturethroid. Not what I wanted but she insisted. It didn’t work so I insisted NP by Acella and she agreed. Back in July I knew something was wrong and complained to her about fatigue and heart palpitations. She said no it’s not your thyroid it’s your Adrenals. Hmmm. I didn’t agree but she’s stubborn about her decisions. Probably because she’s usually correct. But I know this isn’t working and here’s what I think. I think the powers that be want us all on Levothyroxin or synthetic drugs because maybe they get more money that way. There’s a conspiracy here somewhere it’s just too obvious. Feeling awful and getting really cranky with this constant fight for thyroid wellness.

    Reply
    • Janie Bowthorpe

      Donna, of course a maker of T4 might want us on T4 for the money, but that doesn’t mean they have the power or means to stranglehold all the pharmaceutical makers of NDT. It’s much more likely that something else is afoot.

      Reply
      • Bonnie Medd

        I’m beginning to think the same thing as Donna. This is all too coincidental. First Armour, then Naturethroid (which landed me in the hospital) and now NP. If it’s not that, then the only other thought is that there is no one left at the top of any drug companies anymore that are committed to the health of patients above the need to pad their bottom lines and own wallets. I’m so damned frustrated.

        Reply
        • Janie Bowthorpe

          I strongly and logically doubt that it’s a conspiracy to push us towards T4 causing all this. It might even be from ridiculous updates towards pharmaceuticals by the FDA. I and those who work closest with me in this fight have been saying the latter among ourselves.

          I am far more disgusted with pharmaceutical secrecy.

          Reply
          • Hadassah

            I agree with you Janie . Please Keep the Fight Going Strong . We must Not Allow this to happen to us .

          • Sam

            I think this is about raw thyroid supplier. They are all getting it from the same company. Too coincidental

      • housemaid

        Janie, in 2012 Abbott Laboratories, owner of Synthroid, was fined $1.5 billion for illegally promoting their drug Depakote. They have bribed people in the past, so I would not rule it out. It is highly suspicious that CVS Pharmacies has refused to sell NDT and now all the manufacturers of NDT are having trouble making an effective thyroid pill. The late Dr. Lowe said this in a published paper in 2006, talking about endocrinologists and their opposition to NDT: “The specialty’s obstinacy may be sustained by financial incentives from corporations that profit from the practice of T4 replacement therapy.”
        (From “Four 2003 Studies of Thyroid Hormone Replacement Therapies: Logical Analysis and Ethical Implication”) I really miss Dr. Lowe’s knowledge and efforts to help people with our disease!

        Plus you’ve got the FDA working with the big drug companies. Lots of room for corruption there to make NDT less effective and force people toward Synthroid.

        Reply
        • housemaid

          Correction: I don’t have any knowledge of Abbott bribing anybody. It was another company named Alere that they were acquiring which was under investigation for bribery.

          Reply
        • Janie Bowthorpe

          I don’t have an definitive answer, but your post is very good one….

          Reply
        • Susie

          Housemaid, Interesting, I live in the south, I went to CVS pharmacy to fill NP by Acella and they told me they couldn’t get it! I went a couple blocks down to another pharmacy and they said no problem we will order it for you ,we don’t have it in stock, it was there the next day, it was from the Georgia facility. So, for some reason CVS wouldn’t provide NP to their customers.

          Reply
  166. Amanda

    Uh oh – We also need to talk about Thiroyd NDT. I have been taking these for several years but my latest batch 1500057 is different. The soft coating is now hard and has a chalky taste and the tablets seem to be totally ineffective. There is also a shortage of suppliers and they have been told that because ingredients were imported from China who has increased prices, Greater Pharma won’t be making them anymore! I have written to Greater Pharma but they haven’t replied to a not very great me! I am very worried now and don’t know which NDT to use. I don’t want to go back to the hell of levothyroxine…

    Reply
    • Janie Bowthorpe

      Amanda, look at the light green box in the blog post. No one has to go back to just T4.

      Reply
    • William

      In regard to Amanda’s concern specific to “Thiroyd”. I received batch lot # 1500058 and it is in my opinion inert/containing NO T3/T4. (felt terrific on Nature-Throid).

      Reply
  167. Debbie T.

    Janie, I was trying to post a screenshot from the GoodRx site that confuses me: two different looking 60mg tablets of NP; the ones on the left say manufactured by AvKARE https://www.grxstatic.com/d4fuqqd5l3dbz/products/DrugItem_20949.JPG
    are darker with flecks, and the ones on the right say manufactured by Acella
    https://www.grxstatic.com/d4fuqqd5l3dbz/products/DrugItem_26458.JPG
    and are lighter.
    Do you think the AvKARE tablets could be the problem? I am going to request my next fill from Walmart be with the Acella tablets. I will also contact Acella tomorrow and inquire about the AvKARE ones.

    Reply
    • Janie Bowthorpe

      It’s a potentially good question worth exploring. AvKare “manufactures, markets and/or distributes more than 189 drugs in the U.S.” https://www.drugs.com/manufacturer/avkare-inc-428.html

      Reply
    • Jeff

      I have just called in a refill to Rite Aid in New Hampshire for 180 – 60mg tablets for $32.66(Good RX)
      the best price in a long time. But I had the pharmacist check and the tabs have “AP” on one side and
      “330” on the other. When I get the pills tomorrow should I expect a color change?
      Thanks –Jeff B.

      Reply
      • Debbie T.

        I believe the # on the pills correlates to the dosage, i.e. 330 = 60mg, 331 = 90mg.

        Reply
      • Cincolo

        I noticed the difference with just the smell alone. Both my 60 mg and 30 mg pills have the stronger smell. The color is also slightly different with the flecks. I even started refrigerating them because I thought the heat was making them smell that way.

        Reply
  168. Debbie T.

    I and 63 years old and have Hashimoto’s. I feel like I’ve been on almost every brand of thyroid—Synthroid, Armour, compounded, Erfa, Tirosint, NP, Cytomel, generic T3-only, WP, and now NP. I take four 60mg tablets a day. Last labs in March 2019 were: Free T4 1.43 (0.82 – 1.77), Free T3 4.2 (2.0 – 4.4); temps were good; I felt pretty good although weight was coming off VERY s-l-o-w-l-y. My last fill was mid-July. I just returned from visiting family out west, and couldn’t understand why my “jet lag” persisted for days; every afternoon I “hit the wall” in my energy level. Then I read about NP possibly changing and wondering it that is a factor in my lethargy. Went thru this years ago when Armour was reformulated. UGH. Am really considering trying Thyro-Gold—would love to hear from anyone who has used it successfully. I’ll post on the FB page.

    Thanks, Janie, for all your efforts and getting this information out there.

    Reply
  169. Michelle Sarchiapone

    NP is no longer working for me.
    I was stable on Naturethroid for years and years until early 2018 when I noticed my TSH was suddenly unusually lower then it had been previously. Like VERY LOW. I am recovering from exposure to black mold so it was very hard to tell at that point if medication was the issue or my CIRS. Plus I have a pituitary issue…so my ND glossed over the change. But it seemed thyroid related as I couldnt get my hair to stop falling out which is always a major symptom for me that my labs are low (and they were) and at that point, I was fairly well recovered from the mold exposure. Fast forward to the end of 2018 and NT ran out…which in a way I was glad….simply because I had had questions about the efficacy for the whole year prior. I switched to NP thyroid fairly effortlessly in Feb or March? It didnt really slow down the hair loss completely but enough. My last labs were much better then the previous year with NT, but only a mild improvement (definitley not as good as the labs prior to 2018 on NT) My TSH was lower weirdly, but my free T-3 was towards the top of the range, and my T4 was just a smidge over the low line. That said I was feeling great so I didnt mess with it. Then a few weeks ago after a refill I woke up one morning with a major sore throat. My thyroid was clearly tanking. And thats when I started to feel terrible. Fatigue, numbness and swelling in legs and feet, dizziness, light sensitivity…on and on. I began to raise my dose. I got another refill (because of the raise) and the smell and taste are 100% different. Instead of tasting like pork, it has a weird fruity smell?? and weird taste of fillers. Within a few days of taking that script I felt like I was a zombie despite the jump in amount. I had a couple days of the old formulation laying around and took it this morning and immediately felt alive again. I feel so overwhelmed as clearly none of these NDT’s can be trusted anymore. I have no idea what to do!

    Reply
    • Michelle Sarchiapone

      A little additional info: In 2018 when on the iffy NT, I could not lose weight to save my life. Which for me, is highly unusual. I am extremely active. As soon as I switched to NP I lost 10 pounds. In the last couple weeks I have seen some weight creep and bloating.
      I suspect there is a issue with the pork source which is why ALL the NDT is now less then optimal. Might try thyro-gold. Love to hear others experiences!!

      Reply
      • Sam

        I believe this is the case. The raw thyroid is being outsourced and common to all brands.

        Reply
  170. Corey

    Has anyone reported being able to optimize again on any NDT? Is it simply a question of finding a high enough dose again, or are patients moving to more T3?

    Reply
    • Janie Bowthorpe

      Many, many, many of us have optimized on NDT. We have worked to find our optimal dose which puts the free T3 towards the top part of the range, and the free T4 midrange. Both. But we have to have optimal iron and cortisol, too, to get there without problems.

      BUT…with so many NDT’s now having gone south, it’s not a bad thing to get optimal on T4 and T3. Some even feel that Armour has worked. Or the OTC versions.

      Reply
    • Janie Bowthorpe

      There are some who say they are doing well on the changed and way more expensive Armour. But we need to see their free’s to see if they are optimal, because you will feel better on NDT even on non-optimal doses, but it eventually backfires if one isn’t optimal. We see the latter scenario all the time.

      Reply
  171. Thy Roid

    Today I decided to eliminate the NP entirely and switch to Levo + T3. Despite reduced doses (several reductions) in both NP and T3 I really haven’t felt hypo until today which makes me think I’m either getting way too much from NP, which is at odd with what is reported here, or I’m reacting to something else.

    How long does it take for a reduction to result in hypo? I want to know if what I’m feeling today is directly the substitution of Levo for NP or if it’s just the cumulative reductions this week finally catching up with me.

    Either way I’m done with NP and possibly NDT altogether. I feel like I’ve been poisoned.

    Reply
    • Janie Bowthorpe

      Because of the T4 in NDT, of course you felt fine for a while. It can still be converting for up to a week. But in your next-to-last paragraph, you only mentioned Levo. You are going to also be on direct T3, right?

      Reply
      • Thy Roid

        Sorry… it’s complicated.

        Previously doing well at 30mg NP + 25mg T3 (15 in the am, 10 in the afternoon).
        Reduced to 15mg NP + 25mg T3 when I started feeling funny about 10 days ago.
        Reduced to 15mg NP + 15mg T3 (morning only) beginning Friday.
        Eliminated NP today took 12.5mg Levo + 15mg T3.

        Now I feel pretty down. Heart palps reduced but not gone yet. But I really felt no reduction symptoms at all until today.

        Reply
        • Janie Bowthorpe

          Maybe you went the wrong way with the T3….

          Reply
          • Thy Roid

            Funny you say that… it does seem that the T3 relieves my symptoms rather than making them worse. I was wondering about that.

            Question for you: are heart palps always or usually a function of too much thyroid hormone (e.g., hyperthyroidism) or are they also possible or even frequent for people that are suddenly hypo?

            My doctor seems convinced that this is hyper not hypo causing these problems and he points to my typically low TSH as the evidence for this (0.085 last month). He has been willing to treat me by what works as long as we didn’t end up here, but now… here we are.

          • Janie Bowthorpe

            Bingo.

            And heart palps are common with being underdosed, as you may have done to yourself. They can also be common with an adrenal problem.

            NO about the TSH. He’s clueless but at least he will still treat you.

  172. Kaci

    This is happening to me, as well. I’m ok with the change and would be ok with having to have dose adjusted. I just wish the Pharmacies were aware of (or care) how these affect us. My new pills read 330 but are grey and taste like what a dirty litter box smells like. I’ve set them aside and stopped taking them. After reading the responses, I’m wondering if my batch is somehow spoiled (grey color and bad taste) and not related to the new batch.

    Reply
    • Donna

      I have 30mg and 60mg. My 60’s were all procured from Rite aid pharmacy (in NY state and actually one is a walgreens pharmacy in a rite aid store)….3 batches of them (330’s) and none are discolored and none smell nastier than they should. That said, I am fatigued (partly may be due to not enough sleep and I am now optimized). My labs coming early September will tell me…. I also store anything more than a months supply in the freezer and only take out MAYBE 1/2 months supply at a go. AND when i stay in florida, my pharmacist put in a desiccant.

      Reply
  173. Hayden Murray

    I was just about to switch to NP, but guess i won’t now! A lot of people here talking about thyro-gold, think I’ll give that a try.

    Does anyone know if it an also be taken sublingual? Just as it’s bovine. Also, how many mcg of t3/t4 are in 300mcg of thyrogold?

    Thank you!

    Reply
  174. Julie

    I just was totally optimal. My dr said I should frame my bloodwork. He then refilled my np thyroid and I noticed it looked and smelled different and at first I thought the pharmacy had substituted another brand. I then saw it was np on the bottle so I compared the pills thinking maybe they put the wrong ones in the bottle. Sure enough they were stamped the same but looked, smelled, and split differently. I have switched around from wp to nature to np. I feel like some of my symptoms are back too. My feet are swollen and couldn’t fit into my strappy sandals the other night.

    Reply
  175. Dee

    I was on Armour for 10 years and was optimal until it was reformulated. Went through 2 years of misery, until I
    found NP by Acella, and have been optimal for 8 years! Now sick again. I thought the last Rx of
    pills had been exposed to humidity or something, since they are VERY bad smelling and tasting.
    Now I can barely make it through the mornings, even on 1/2 pot of coffee, and all the old low thyroid
    symptoms are returning. WHY do these companies have to mess with the formulations when people
    are doing well? Does it have to do with cheaper production or something (money is usually the culprit).
    THANK YOU JANIE for solving this mystery.

    Reply
  176. JC rosE

    I tried the NP to see if would feel better…they were so stinky and i never had that issue with nature throid. First i had terrible dry eyes to the point i went to the eye dr, i changed back to nature throid and the eye problems went away. I still have not the energy i used to have , have plantar fascitis on one foot, and have hair loss for several years now that may be unrelated…on 2.5 g once daily. IT IS ODD THAT ALL THE NEW ”’variations” HAVE SPECS IN THE TABLETS….what are these specs in all the new pills….what is that….that should be our question…we all see that….in common….the NP smelled like dead fish or sour raw pork meat or bacon left out too long….The NT has no smell but pills are smaller, appear harder, and BOTH HAVE DARK SPECS……..is that a new additive…. DID BIG PHARMA OR THE FDA make them make changes to turn people away from ndt med back to synthroid . DID the bad pig scare overseas make a shortage so we have more fillers and less hormone, how is it EVEN POSSIBLE…that TWO COMPETITORS have DARK specs if it is not ORDERED CHANGE UP by fda???

    Reply
    • Janie Bowthorpe

      “Big Pharma” is just a term to describe all the pharmaceuticals collectively. They wouldn’t shoot themselves in the foot when their goal is to make money. But your question about the FDA’s role in this has been talked about privately and what part they might play in this disaster. And your comment about the dark specks is also a big question.

      Reply
  177. Dawn Kaplan

    I called Express Scripts today and spoke to a pharmacist about the new batch of pills I received last week. She put me on hold for a long while, came back and said she could find nothing from Acella about any change in the medication. She said the smell could be from being oxidized while being in transit from the heat. She is sending out a new rx for me. I asked for the lot number and will compare if the new pills I receive are the same and/or from the same batch. I don’t know if this will prove anything. Mostly for my own curiosity.
    I am sick over this! Not only am I in the throes of menopause, but now having to have the stress of this.

    Reply
  178. Liza

    I had horrible problems on NP thyroid. Before NP and now Im on levothyroxine.
    On NP, all my labs showed TSH through the roof, and no help with T4,T3 whatsoever. My labs before were close to optimal, my Dr. just wanted to see if this meds would be better for me. Nope!
    On top of that Ive got lichen planus all over my body, that non of the steroids creams could help. I stopped taking it as soon as I got my lab tests and went back Levothyroxine and started LDN. LDN was the only thing that healed my awful lichen planus outbreak.

    Reply
    • Janie Bowthorpe

      Sounds like you were severely underdosed on the former NP tablets.

      But in the meantime, might want to listen to the wisdom of patients and consider adding in direct T3 to that T4.

      Reply
      • Kathleen

        Please tell me about adding T3 and T4. Is this something I ask my dr to call in? I know nothing about this. Tia

        Reply
        • Janie Bowthorpe

          It’s an alternative, yes. If someone was optimal on NDT (free T3 at the top of the range; free T4 midrange. Both), they ask for the equivalent in T4 and T3. You figure out the equivalence by understanding this: one grain of NDT is equal to 38 mcg 4 and 9 mcg T3.

          If NDT was not optimal, you can still go to the equivalent dose with the two synthetics, but we will need to raise to be optimal.

          Reply
  179. Rita

    I found something interesting. On the GoodRX app, if you look up NP 60 it shows two photos, one of the old one, one of the new one. They are very different looking. I don’t think it shows photos for 2 pills of any of the other doses. But my 128 is definitely new (and disgusting). Weird, I just noticed the first photo of the NP 60 says manufactured by AvKare. That is the new pill, speckles and rough. What in the world? Is it a typo?

    I wasn’t optimal on Naturethroid (after the change) and then read that NP was better here, and decided to try to get optimal on NP with the higher doses, what unfortunate timing. My NP 128 pills taste like poison, how insecticides smell. I have been taking NDT for over 15 years, no pill has ever tasted like that.

    I think I might just try a higher dose of Naturethroid rather than risk taking higher doses of this new NP. I have taken many pills/supplements and never had one that tasted like insecticide. What filler could taste so horrid? I just don’t trust it and don’t feel comfortable taking it for any length of time. There is something seriously wrong with it. I chewed it and the horrid taste was throughout the pill. I don’t want to ingest that every day.

    If larger doses of Naturethroid don’t work, I will try Armour, and if that doesn’t work, synthetic T3,4. Honestly, I am about ready to give up on NDT, very frustrating and sad…

    I also emailed NP and I am going to return my NP 128 to Walmart due to its disgusting smell/taste and talk to their pharmacist. If we all contact the company and return the pills, maybe something can get done?

    Reply
    • Janie Bowthorpe

      From drugs.com: “AvKare, Inc. manufactures, markets and/or distributes more than 189 drugs in the United States.” i.e. they do it for other companies.

      Reply
  180. GregS

    My wife no longer has a Thyroid….same story I read here often….nodules…might be cancer…remove it…removed it….checked it, no cancer…
    She’s on Levo. Seems to do ok….no symptoms….so she thinks. Yet she diets and diets and can’t lose weight, has extremely dry skin, and I have to remove a huge gob of hair from the shower drain every two weeks……luckily she has a lot of hair, no tiredness symptom yet. Yet I’m afraid this might be a time bomb, she isn’t aware of.

    Now I’m hearing about this latest panic about the porcine natural thyroid medicines again…..the choices are shrinking…
    On the other hand the Chinese connection may need to go away for your sakes…..if you think they care about Americans you are mistaken.

    What about the other non-Chinese sources of natural Thyroid? Especially, what about Tammy (Lowe) Carter’s bovine Thyro-Gold? I bought a bottle of her most potent pills for my wife to try…….but she won’t. Want’s a “MD doctor” to prescribe it, etc. (Good luck with finding one that will in this area) She might listen to you guys…….

    Reply
    • Janie Bowthorpe

      That is sad about your dear wife. She doesn’t understand that what her doctor is giving her has caused problems for millions over the years.

      Reply
  181. Judith W.

    On NP Thyroid; I take 180 mg. or 3 grains every morning. Just started a new prescription July 1; gained 10 lbs. in 2 weeks.
    On 1 side of the pill is AP and the other is 331.
    Thoughts on #331?
    STTM!!!
    Thank you!

    Reply
    • Janie Bowthorpe

      It’s the changed tablet number, say many.

      Reply
      • Shannon

        I was wondering why my NP Thyroid tasted so bad. I usually let it start dissolving under my tongue while I get my other meds ready but just cannot do it with my 90mg tablets. They are horrible tasting. So far it seems like everyone is experiencing this with the pill with #331 on it. That is not true in my case. My 60mg pill refilled in mid July is #331 which seems fine. My 90 mg pill refilled in mid July has #330. That is the one I think is bad.

        Reply
      • Andrea

        Interesting!! I have that same pill with markings and literally gained 10lbs in a week!!! While tracking food and exercising every day!! Could it be!?!? I am tempted to just go to tirosint or levo and t3. Who has time for this nonsense!?!?

        Reply
        • Sam

          I’m on 90 and they are rancid. Awful tasting and I feel awful sore and tired.

          My appetite is much harder to control.

          Reply
  182. Shayda

    I just tried the new one I had picked up from the pharmacy and you are right. they are not as sweet and definitely taste different. Definitely NOT the same formula.

    I have emailed NP Thyroid for an explanation and let them know I am considering switching to another brand.

    Incidentally my local Walgreens tried to switch me to Armour without telling me. I only knew because the price was so high when I was checking out…

    Thanks so much for keeping us updated!!!

    Reply
  183. Diana

    My pills have the AP on one side and the number is 331. The bottle says NP THYROID 90 MG. Generic for ARMOUR. Mfg. Acell. So what am I taking? Any clue?

    Reply
    • Janie Bowthorpe

      People are saying that the changed tablets do have 331 on them. But you’ll know by noticing a far stinkier smell, and a very bad taste, which is what others are saying about their changed tablets.

      Reply
      • Diana

        My pills were changed a few months ago. I was taking the Levo /lio and feeling pretty good, made a fuss when they changed but was told these are the same thing. I have been feeling really bad but just assumed it was my age. My doctor does not do the right tests so I have no idea of any of my levels. I also have Afib and thought the heart palpitations were just that, never suspected my Thyroid. Going to try to get my Dr. to do some more tests. Are there any good supplements to help with problems? I was diagnosed when I was 16 and I just turned 73.

        Reply
      • Emily

        My changed tablets have 328 written on them (120mg). I’ve sent a message to Acella at https://npthyroid.com/contact/ to ask about the changes.

        Reply
      • Judith W.

        Oh, yes Janie…the smell is terrible! Especially difficult since I haven’t eaten meat in 35 years!
        Called my pharmacist at Walgreens and of course they have nothing to say.

        Reply
      • Sherry Forslund

        My, impacted, 120mg has 328 on it and my 30mg has 329 on it and the bottle has more “powder” on the inside than the previous bottle after 90 days

        Reply
  184. BarbN

    I began taking NP last fall after struggling terribly to optimize my Naturethroid dosage after the changes. Finally, I switched to 180mg NP and started feeling better and felt good until probably May this year. I started noticing I would have no appetite when I should be hungry, tiredness was creeping in, brain fog, and bloated feeling on and off.

    Sometime in June or July I’m sure I started taking the new pills because suddenly in late July and August I was gaining weight, very winded when exercising, having joint pain, recently had headaches (some were similar to a migraine and I normally never have headaches), and the weirdest symptom was tired eyes with pain like my eyeballs were hurting toward the end of the day…I was initially thinking maybe allergies…I just wasn’t sure what was causing all this but didn’t rule out that it might be the NP…then I received Janie’s blog email and it all became clear.

    Due to my struggles with Naturethroid I decided to stop taking the NP the next day on 8/23. I replaced it with 300 mg Thyro-Gold that I had on hand from my desperation last year…it was unbelievable but the eye tiredness and pain were gone and the joint aches…I even feel more clear headed.

    I also am curious if anyone has had a refill that includes the old and new pills? I took some photos and even asked my husband and kids to confirm what I was seeing…there are 3 old pills and the rest are new pills in my latest refill from 8/7…there is definitely something going on. I need to review my bloodwork over the last 6 months and will post the history…

    It seems like these issues are not getting better with the NDTs so I plan to try the otc products and optimize using bloodwork…so bummed…

    Reply
    • Janie Bowthorpe

      Yes, there are some who have reported a mix from their pharmacy. It may be why there have been great photos of both lately to show the differences.

      Reply
    • Barbara Arendall

      I am curious if you don’t mind.. why did you stop the Thyro-Gold? I am taking Throvanz and doing well so far.
      Good luck.. hope you continue to feel okay.
      another Barb!

      Reply
      • BarbN

        I don’t mind at all. I stopped the Thyroid-gold only because my doctor agreed to switch me to the NP…I had no problems with it. I unfortunately only took it for a short time… I have also ordered some of the Thyrovanz and plan to try it. It is encouraging to hear you are doing well with it. Thanks for sharing!

        Reply
        • Tina

          I just refilled my NP prescription this past Tuesday. It has AP on one side and 329 on the other. No weird smells, just normal. I take 3, 30mg a day. Maybe the bigger doses are what’s changed.

          Reply
          • Cincolo

            I’m on 1 grain and 30 mg tablets. I noticed the smell on both of them now.

      • Jeni

        @Barbara Arendall–how much Thyrovanz do you take? Where you previously taking NDT? If so, which ones/dose?

        Reply
  185. Rita

    I recently switched from Naturethroid to NP because of hair loss, weight gain, and anemia. I started taking 90 mg of NP and after 2 months was not optimal, so I was just switched to 120.

    The 90 mg pills were from
    Walgreens and didn’t smell bad and tasted sweet. The 120 pills are from Walmart and look different, smell chemically, and taste literally like pesticide. No comparison between the two.

    This same thing happened to Naturethroid. The pills used to be sweet and easily dissolved and then tasted different and were harder. And then stopped working for me.

    I noticed on the NP website that they released the 120 in July 2019. Maybe the suppliers changed the fillers?

    My main problem is whether I should even try to take this for two months and then do testing knowing what I know now. The taste is very concerning, like poison, not pig. I have never had a pill or supplement taste like this. And I could try to find the older pills, but if they are changing all of them as it sounds like from above, why mess with getting optimal and then not being able to find the old pills?

    I can’t believe this. I have been on Armour, Naturethroid, and NP. I was optimal for years on 60 Naturethroid until they closed down.

    I am clueless what to do now because I worry I will be a bald blimp in 2 months. Maybe I should try larger doses on Naturethroid as my doctor initially suggested? At least Naturethroid doesn’t taste like roach spray.

    I have been on NDT thyroid for over 15 years and I am finally agreeing with people who say you can’t trust this product. These “change in formula” issues started with Armour. Something is happening and these companies are lying to us.

    Reply
    • Janie Bowthorpe

      The problem is that Pharmaceuticals are secretive to the point of being insulting to informed patients. The next steps are up to each individual:

      1) Raise the changed NP tablets and see if it helps. Doing the frees would be a good thing. Working with your doctor will doing this. Etc.
      2) Crush the tablets before swallowing. One gal said she made the changed Armour tablets work this way. A sweetener could be added by the individual to tolerate what is being described as a horrid taste
      3) Move to Armour
      4) Move to synthetic T3 with synthetic T4 (one grain of NP was 38 mcg T4 and 9 mcg T3)
      5) Move to over-the-counter NDT “supplements”

      Reply
      • Rita

        Thanks Janie! I might try this new disgusting pill for a few weeks since it is higher than my last dose and see how I feel. I crunched up the one this morning in my teeth, so will continue. So disgusting tasting! If this doesn’t work I might consider moving to Armour, even though it is so much more expensive. Thank you for your advice.

        I am beyond frustrated! Hate testing out this new NP… Maybe I will be lucky, but probably not.

        Reply
        • Janie Bowthorpe

          We’re all going to hope.

          Reply
          • Judy

            I asked the man I spoke with at Acella this week where their raw material comes from. He wouldn’t answer that question. I was just wondering whether it comes from China or from the same source where other NDTs get their raw material.

            Also it still doesn’t make sense why places like Women’s International can’t get raw material but companies like Acella can. Couldn’t WIP get it from the same source?

            I’ve had it with all the mystery, secrecy, deception, and lack of transparency that are ultimately badly damaging many, many people’s (mostly women’s) health and lives. And then that affects the lives of all those people’s families in a trickle-down domino effect.

            Those pharma companies and their associates are obviously not in it for any type of benevolent reason. They obviously don’t care about us. All they care about is money and their own interests. That’s sick (no pun intended), unethical, immoral, inhumane, and lacking in conscience.

          • Janie Bowthorpe

            Your last two paragraphs definitely represent how many of us are feeling….you said it well. May I include those two paragraphs in the actual blog post?

          • Peggy Shinkle

            Have been on Armour Thyroid for 5 yrs. Current internist keeps changing dosage to try to fix BP and angina. Have been Eu-Thyriod for 25 yrs due to thyroid toxicity. New modules appearing. Need to get a handle on BP and angina, but so far, no luck! Any experience on getting Internists, Endocrinologist, and Cardiologist to work TOGETHER?

      • Kathleen

        Which Thyrovanz do you recommend?

        Reply
  186. Sherry Forslund

    After seeing a couple of posts I contacted my pharmacy as a received a new batch and starting it last week. I didn’t notice symptomss but the taste made me gag and with my dose yesterday I separately took the 120 and 30 to figure out which was off so I called Optum RX and asked for a replacement bottle be sent for the 120. For that to happen I had to talk to a pharmacist who basically said that color and taste variations are “known” with these types of products and even the manufacturer and medically it was just fine and I needed to take my medication. She would not listen to me at all that there was an issue with this batch, I ended up having to call back, complain and talk to a diff pharmacist who is sending a replacement but I am genuinely concerned about what will arrive. I did contact acella (NP Throid) via a Facebook to report the issue as well and no one had responded.

    Reply
  187. housemaid

    I got a 3 month supply of the NP 120 mg tablets from a Walgreen’s in NC on 8-21-19. Had to wait several days to get the order in as usual, but they are the same good NP tablets I have been taking and doing well on. I am afraid now I will get the bad NP after 3 more months. I have been through this with Nature-throid and WP thyroid before and hate to see this happening yet again.

    I wonder if the recall of bad batches of the porcine thyroid from Sichuan Friendly Pharmaceuticals in China a year ago has anything to do with Nature-throid and now NP changing. The FDA alert said that the porcine thyroid had certain batches that were “inconsistent quality”. They said that the lots may not be labeled with the name “Sichuan” but may just say “Thyroid Powder”. The FDA then made this ominous statement: “FDA also recommends that patients discuss FDA-approved hypothyroidism treatment options with their doctors, as combination levothyroxine and liothyronine products are not FDA-approved.” Well, we know what that means–Synthroid.

    Reply
    • Thy Roid

      This is really interesting. The timing would explain the sudden shortage of Naturethroid last year and might also explain the inconsistency in the products that we are all evidently experiencing.

      The thing is, I won’t feed commercial dog food to my dog because I don’t trust the manufacturers to avoid ingredients from shady Chinese producers (who poisoned and killed thousands of pets here), so why would I trust the same Chinese pork producers for my medication?

      We need more transparency in the pharma industry so we can make more informed decisions about what we buy and take.

      Reply
    • Steve

      Not sure if this is true but I heard that much of the porcine used to be harvested in Puerto Rico. After the hurricane devastated the island the manufacturers have had to look for other sources.

      Reply
  188. Lynn

    I’m blown away that I saw this post today because just last night I was wondering why I was struggling with major palpitations. I usually take 135 mg NP Thyroid in the morning (1 + 1/2 90s) and 90 mg at bedtime. I have no thyroid and my Primary doc is giving me a hard time about my dose (previously prescribed by a Functional doc I no longer see) so had cut down to 1 90 2x/day for a week prior to labs I’m getting next week. I was diagnosed with AFib in January and the palpitations I’m feeling are not that. They are typical hypo palps and now I know why! I just picked up a new refill of 90s last week. I will raise my dose tomorrow and see if the palps disappear. Joints are aching more also and I’ve been “down” last few days too. SO glad I was this post. But what a bummer.

    Reply
  189. Deana Newcomb

    Yes, it smells bad. But worse, I have been half-dead (sleepy) since my new script. Maybe make it through a work day—but come home and go to sleep for 1-2 hours. Also, exercise was debilitating rather than helpful.

    Reply
  190. CO

    15 months after total thyroidectomy and I’m feeling pretty good on 2 grains np and 75 mcg cytomel. And now this. Sigh. I heard the horror stories with naturethroid.

    I have a good stash of the old np tablets, so I should be able to prove I’m optimal with a few more months of the old stuff. Then maybe things will be clearer with what’s going on.

    Reply
  191. Elaine

    So which brands are good then? Thanks

    Reply
    • Janie Bowthorpe

      The million dollar question. First, we can always try chewing up the NP and see, plus testing our frees.

      Reply
    • Paula Wertheim

      My husband and I have been using “Thyroid-S” and a cheaper but equally effective product called “Thiroyd” – both from Greater Pharma Manufacturing Co. Ltd , Thailand. After three years , we have nothing but praise for the quality, availability and PRICE of these excellent products. For less than $80 USD you get 1000 tablets per bottle!
      Btw, we live in Israel. First, we tried Armour , then NT from Canad. The price of both became so ridiculous we were forced to take a chance on the Thailandi products. No regrets!

      Reply
  192. Dawn Kaplan

    Hi All,
    I remember when Armour changed the formula about 10 years ago. I would crush the pill and sprinkle Dextrose on top, then swallow it down with water. It worked. I did this for years and continued to do well on Armour until Forest Labs sold it and the price sky rocketed. I switched to NP and did well on this as well. I have about two months left of the pills of the old formula, and my new rx is their new version. There clearly is a difference.
    Is anybody that has the new formula willing to try this and see if there’s a difference? I would buy the NOW pure dextrose. It worked beautifully.
    Thank you in advance, and thank you Janie for posting this! I don’t participate much, but am a loyal reader!

    Reply
    • Janie Bowthorpe

      Glad you shared your experience of crushing and that it work. Who knows. It might with the changed NP Tablets.

      Reply
      • donna cason

        Why would crushing it work if there is not enough active ingredients in it? I take sublingually.

        Reply
        • Janie Bowthorpe

          Because it’s the hope that the problem is about fillers and/or the way the tablet has been compacted. We won’t know until it’s tried.

          Reply
        • Janie Bowthorpe

          This may be a duplicate response by me. Can’t see my former response. There is no proof that there is not enough active ingredients causing all these problems. It could also be the fillers–the question becomes why is the changed tablet thicker than the former very-workable tablets? We don’t know when it’s claimed that “nothing has changed”, which strikes patients as total BS.

          Reply
  193. Anna Akopyan

    My Free T3 is down to 2.4 from 3.1 and free T4 at 1.0. I have never taken desiccated, just herbal such as Gaia thyroid support but never made a difference. I’m now considering getting on desiccated but afraid of what’s to come especially considering all the Pharma changes. Also, I take seriphos for my adrenals. I recently did an iron transfusion so now my iron is super high…will the super high iron impact the desiccated? My functional medicine doc said it shouldn’t but I have a bad feeling. Any suggestions are greatly appreciated!

    Reply
  194. Judy

    Can anyone tell me how the new NP thyroid taste I had a script filled in June. And they smell the same and still taste sweet. Just wondering do they still have a sweet taste and what kind of smell. Do they have now Thanks

    Reply
  195. Susie

    This change is unacceptable. I have been on Armour for over a year now. I have not been optimal on this medication, although it has been much better than the Synthroid generic I was on after a subtotal thyroidectomy. I once switched to NP by Acella and the swelling in my legs went away and the inflammation in my body was noticeably better, although I had terrible bouts of depression. I now suspect that I was on too low a dosage. I was searching this forum for information on NP Thyroid in hopes of trying it again. Now I’m very reluctant to switch. I suspect either the company had tried to cut corners or there is an effort from the FDA or big pharma to eliminate the rise of NDTs. I think it is questionable how endos an other doctors act like NDTs are terrible meds. They were wonderful meds until the FDA and pharma companies ruined them. Why is the question. What is the gain behind eliminating the high demand for these life changing drugs? It’s certainly not for the well being of suffering thyroid patients.

    Reply
  196. Anna-Maria Nicolov

    I’m so glad to hear that it isn’t just me!! I was feeling 110% on WP in 2017-2018! I had just discovered WP after 14 years on synthroid. And then, in August 2018, WP was not being made temporarily and my doctor put me on Naturthroid, which caused major breathing problems … and going back on WP once it was available caused the same breathing problems, though to a lesser degree. I was on a high dose at 4.5grains WP … in order not to experience broncho spasms, I have had to come down to 1.5 grains. And even at that, I sometimes feel awful and I need to use an inhaler everyday.

    Reply
    • Bonnie Medd

      I’m SOOO curious about this!! I’ve told at least three different docs that I believe my breathing issues (asthma) is DIRECTLY correlated with my thyroid levels. Every one of them has told me there is absolutely no correlation. I KNOW I only have asthma when my thyroid levels are whacked. But of course, I don’t have eight years of medical school to know my own body, they do? Bah!

      Reply
      • Laura

        I had asthma for 17 years. At the start I thought it was thyroid and was poo-pooed. Finally found a doctor who diagnosed hypo. Within less than 2 months on armour my asthma disappeared. I too notice tight lungs when my thyroid is wobbling, probably thanks to the changed naturthroid.

        Reply
  197. LiLi

    Dears,
    I have been on NatureThroid since 1999

    Began with 1 x 32.5 mg and moved up to 4×32.5 mg in the winter, 3x 32.5 mg in the summer, over the years. Now, I am at 2×62.5 mg in the summer.

    I moved and the local pharmacy switched me to NP for a similar dose

    I went downhill fast on the NP which, yes, does, smell and taste horrible – fatigue was the worst part

    I went to another pharmacy and got NatureThroid – and am feeling better now.

    Doing tests soon, to see how things are going, as I was feeling tired on the NatureThroid before getting switched to NP.

    Wishing You all, all the best,
    LiLi

    Reply
  198. Bonnie Medd

    Sigh. This really sucks. I just received my dose of 120mg through CVS Caremark. It indeed is a different pill. I have no thyroid. I did horribly on Synthroid. I NEED this as well as so many people. Why can’t we trust our drugs? Especially our drugs that are supposed to be natural! I’m about to do something a bit extreme and get off the prescription rollercoaster altogether. I ended up in the hospital with Naturthroid after they “didn’t change anything”. I previously had a great experience for years with it.

    Reply
    • Janie Bowthorpe

      We can always trying raising it and see. But probably a good idea to do the frees with it, then raise, then a few weeks later, then labs again. And anyone can change to synthetic T4 with synthetic T3 until this ridiculous mess is hopefully straightened out.

      Reply
      • Carolyn

        Hi Janie,
        So concerned just like everyone else. This has me holding my breath. I know I cannot function if I do not have thyroid meds that work. I currently take 2 grains NP. I’m unsure how that converts if I were to try synthetic T4 with synthetic T3. How do we figure out the conversion for that?

        Reply
  199. Pat Boatman

    Do we stay in the optimal as we age? My Dr is trying to tell me staying optimal is shortening my life

    Reply
  200. Martin

    Has anyone switched to compounded desiccated thyroid as an alternative? Our compounding pharmacy has been getting calls regarding thyroid manufacturers changing their formulations. Some of them are switching to compounded thyroid because we always have a supply and the dosing is consistent. We don’t have any manufacturing process that needs to be altered and don’t use additives, binders, colorings, etc. What are everyone’s thoughts on compounded thyroid vs. manufactured thyroid?

    Reply
    • Thy Roid

      That’s my next step.

      Reply
    • Susie

      Martin, I have not taken a compounded formula, although I have considered it lately. Is the cost normally high to have thyroid meds compounded? I would pay a little more for something that works as long as it’s reasonable. Do you have any stats on how patients do on these compounded meds? I think for many of us, it’s worth looking into.

      Reply
      • Martin

        Yes, the cost is higher than a commercially available product. Patients generally have responded well. We try to target the exact dosage you were taking with your previous medication as closely as possible based on the information from the manufacturer. Unfortunately no stats are available at this time but there is really no difference in the active ingredient.

        Reply
    • Carolyn

      I’d like to check this option out. How do we find a good compounding pharmacy?

      Reply
      • Janie Bowthorpe

        Call around where you live, for one.

        Reply
        • Carolyn

          Thanks for your answers Janie. I’m going to get my alternate plans in place. will not go down without a FIGHT for my health.

          Reply
      • Martin

        Yes, you can call around in your area. Do a Google search for compounding pharmacies near you. Some pharmacies like ours will ship out-of-state as well. We ship to 26 states but are located in California.

        Reply
  201. Suzanne

    My labs came back bad. My T3 is too high, T4 in basement, TSH back over 3.5. I’ve had some issues focusing, tiredness, hair loss, and all the usual reformulation symptoms. I too have gone from Armour, ERFA, WP, and now NP is bad. I’m not sure what to do. Increased dose did not help.

    Reply
    • Deb

      This is what happened to me this summer on Naturethroid.

      Reply
    • Jen

      This is exactly what happened to me! High FT3, low FT4, but low TSH and normal rT3. I take one grain of NP and 56mcg if Cytomel.

      I’ve been losing handfuls of hair, my depression has come back, and I can’t seem to get my body temp regulated. I have no idea what to change at this point.

      Reply
      • Janie Bowthorpe

        Jen and all, a high FT3 can be pooling, which means it’s revealing a cortisol problem. So doing a saliva test is important, we’ve found repeatedly, to see exactly how the cortisol is messed up, thus what to treat: https://stopthethyroidmadness.com/saliva-cortisol

        The 2nd common cause we’ve seen is being on too much T3, which is worth exploring, too.

        Reply
        • Jen

          Janie, I was optimal up until July, when I noticed the weird smell in my refill. I have lost about 30 pounds over the last 6 months (intentionally) so I think that might have caused my high FT3, but I can’t explain the drop in FT4.

          Reply
  202. Thy Roid

    Check this out. Been on 30mg NP + 25mg of T3 for months. Doing great. Decided to try to reduce the NP to 15mg and at that point I got a refill of both 30 and 15mg NPs. That’s when the trouble started. Trouble breathing, everything began to hurt. Switched back to 30mg to try to straighten out but then massive heart palps began (so bad they wake me up). Then I read that the NP might be bad. I have gone through this with Armour and Naturethroid before so I’m not unfamiliar with this, but this set of symptoms is totally new to me. In the past reformulations would make me feel hypo, but this… this is different and worse. I don’t know what to do… reduced to 15 again today to try to get rid of the palpitations.

    Reply
  203. Sondra

    Im wondering if there is a Conversion table to go from NDT to synthetic t3 and r4. This if all else fails.

    Reply
  204. Pat Boatman

    Would my tongue swelling and having ridges been a sign of under dosing? I’m on 2 grains of NP thyroid and 67 yrs old. Thus has been goung in for 3 weeks now

    Reply
    • Janie Bowthorpe

      It has for some per their reports. But…2 grains is usually underdosing the majority, even if for a minority it may not be. Thus, hypo symptoms will come back. We all have to be optimal, which puts the free T3 at the top part of the range and free T4 midrange. Both. And we have to have good iron and cortisol to get there without problems. So for the time being, we can’t prove that your issues are from the changed tablets…

      We are wondering though if those who are underdosed will feel even worse on the changed tablet. i.e. a less effective tablet on top of hypo symptoms from being underdosed.

      Get the frees tested!

      Reply
  205. Katie

    This makes perfect sense to me now!! I currently take 120 of NP and have been struggling most of the summer with the return of symptoms! My hair is falling out again and one day I had accidentally left the pill bottle open on the counter and was trying to find the “rotten” smell….I finally realized it was actually coming from the open bottle of NP!! It was SO gross smelling! I hold my breath when I open it now! I also struggled with NatureThroid and couldn’t find it anywhere anymore which is why I asked to switch to NP Thyroid. I think the first bottle was the old one and I felt great but then got a refill and things have tanked!! Ugh!!! I live in the Kansas City area!

    Reply
    • Janie Bowthorpe

      One thing though….though there can always be exceptions, 2 grains is usually underdosing the majority. Thus, hypo symptoms will come back. We all have to be optimal, which puts the free T3 at the top part of the range and free T4 midrange. Both. And we have to have good iron and cortisol to get there without problems. So for the time being, we can’t prove that your issues are from the changed tablets…

      Now we are wondering if those who are underdosed will feel worse on the changed tablet, since if it’s not as effective, it will make an underdosed person even worse…

      Get the frees tests!

      Reply
  206. Alison

    This doesn’t help your cause because I was put on a lower dose before getting new nature throid pill (could this be an issue all on it’s own because I see a lot of this) but I, like you said I got my hypo back. I was so excited my levels were going up. I also felt better not on them like I was taking too much. But there are other factors involved in my story. The point is I started feeling very shaky on the new stuff. My doctor thinks I’m reacting to a filler but I don’t usually have allergies besides gluten, never tested just by symptoms. I’m now on armor just started and praying for getting better. My main issue is anxiety but I also have low progesterone and adrenal and possibly estrogen but I’m not sure on the estrogen. Doing labs soon. Any suggestions on what all to test for? My doctor is schooled in the natural thyroid but I’m not sure if he tests enough. I used to see one of the Drs that wrote the stop the thyroid madness book but he followed the medical medium and it got to the point I didn’t feel comfortable with that. But he got me mostly feeling better but whether it was me or him we never addressed adrenal or progesterone.

    Reply
  207. Sara B

    I was optimal for the first time in 4 years. I have felt terrible, run down, and tired since my last refill. I fall asleep often. I think I need to go have labs done to see where I stand. I have pictures of the old and new together, if anyone needs them. They are clearly different.

    Reply
    • Janie Bowthorpe

      Darn it. Your experience does seem to validate what some people are saying about the changed tablets. Please keep us informed. Might want to post the former labs on the former tablets, and the new labs on the changed tablets. That will be huge info!!

      Reply
  208. Jan

    Thank you for this post. All of my reoccurring symptoms make sense now. I have been on Naturethroid, then NP and just recently back to Naturethroid. I noticed the bad smell of NP in the spring. I began to experience low energy, easy weight gain, and joint pain. So, I’m back on Naturethroid, only to learn the formula has changed! I have no idea if my levels are optimal because my doctor only goes by the TSH and my symptoms.

    Reply
  209. Sondra

    I started my new batch of NP thyroid about three days ago. The taste is disgusting! I can tell I am having hypo symptom starting. My first symptom is dry eyes. I have been optimized for several years. I have been through this nightmare several times, like most people. What do you know about thyro-gold. Could that be a option.

    Reply
    • Janie Bowthorpe

      Then you are another good example that there just may be something wrong with the new batch of NP. Yes about Thyrogold. People have overall been pleased.

      Reply
  210. Krista

    I’m thankful to be reading this blog! Back in July I did a refill of my NP thyroid. Immediately I noticed a difference in odor and appearance, even worse, within days I noticed a change in hypo symptoms. Absolutely crushed to be dealing with another formula change.

    Reply
    • Janie Bowthorpe

      To have noticed a worsening in hypo symptoms just days after being on the new batch is a strong concern. We are hoping that raising the new batch will resolve the clear problematic nature of the new batch.

      Reply
  211. Andrea

    I had half my thyroid removed 3 yrs ago due to nodules that tested as “suspicious” (turned out to be benign). Became hypo immediately, despite reassurance from surgeon beforehand that half thyroid could most likely take over and perform as whole thyroid (I believed him…). The battle to become informed, then find the right doc and medicine then began. NDT, and in particular NP Thyroid, is the only thing that’s ever relieved my symptoms. In April, at 90mg (symptoms relieved) I was at TSH .11, FT4 mid range, FT3 above mid range, RT3 mid range. I felt good, and TSH was low, so doc kept it at 90mg until numbers and/or symptoms changed. In July, I tested TSH .13, FT4 bottom range, FT3 lower range (doc forgot to include RT3). Doc told me to add 15mg, but I was confused because I had also tested high for some antibodies that suggested I had or did have some kind of infection, and combined with the fact that I had had a knee surgery that I was having trouble recovering from, I thought all that could have been what threw my numbers off. So, I figured I would take care of myself a little better, and retest in 4-6 weeks to see what happened. I admit that I did not want to add take the extra 15mg unless it was necessary because – despite hearing on websites like STTM that low TSH is okay – every doc I’ve had (functional, holistic, traditional) seems to worry about that, and it did make me nervous. Hearing this about NDT now has my head spinning however, and although I have not noticed a difference in appearance or taste (I swallow them), I am anxious to see what my next results are. I will have labs done next week, and meet with doc when results come back. This is good info to be armed with before all that happens. This doc is a functional doc, happy to prescribe NDT, and usually pretty well informed about current issues around it (NDT). I’ll report back what I find out.

    Reply
    • Janie Bowthorpe

      Hi. You may still have the former batch of NP tablets, which is a good thing. i.e. the pharmacy you use is still carrying them before they run out.

      Reply
    • donna cason

      There is a good chance you needed more than the 15mg.

      Reply
  212. Robert

    Janie, would it be possible for you to get the two versions of the NP Thyroid analyzed for their full contents to actually see if there is a difference? I can see that there is a difference between the pills that I have been taking and those that my wife has been taking, as you have illustrated, even though they are supposed to be the same. And she has not been feeling good. If the cost of doing that would be a problem we would be willing to contribute to a fund to do so. Some kind of an investigation is needed, especially since Medicare reportedly will no longer pay for the NDTs.

    Reply
  213. Donna Cason

    Is this only happening with 60, 90, and 120mg? I do have a stash of 30mg AND just had labs done last week so I will know if anything has tanked and could switch to the 30mg for 6 weeks.

    Reply
  214. Dedee

    I’m new to thyroid meds. diagnosed with Hashimotos and nodules. I actually feel “activity” – odd sensations in my neck at times – along with other symptoms that align with hypothyroidism. I was prescribed 15mg of NP Thyroid by Acella. It does have an odd odor and taste but I know no different — and I wake up to take it early so that I can drink coffee 30 minutes later. I had only taken Levothyroxine for a short time after being diagnosed with Hashimotos before I requested the NP Thyroid thanks to this site and group. I still get afternoon sleepiness – often taking a cat nap right after dinner because I can’t keep my eyes open.

    Please steer me to information that explains what my readings need to be so I am considered “optimal.” I have very high Microsomal TPO Antibodies at 495. I can’t even find both T3 and T4 readings on these blood test reports – (I doubt they are measured!) I have had one parathyroid adenoma removed and my calcium remains around 10.5. I don’t understand where I’m supposed to be regarding thyroid readings and how often I should get the blood tests – and exactly which tests – just T3 and T4?

    Sorry I’m such a neophyte – I’ve just had doctors that are clueless or deny there’s a problem when I’ve described the symptoms. My current doctor who did give me a rx is being cautious, I believe. I can order my own labs through Sonora Quest. Will you please help guide me? I don’t know what direction to go. Thank you.

    Reply
    • Janie Bowthorpe

      Hi. You do know that 15 mcg of NDT is paltry, right? We always start on one grain (60 mg), then we move up by 1/2 grain every two weeks, slowing down in the 2-3 grain area to retest our free T3 and free T4. Yes, afternoon sleepiness is our sure sign of still being hypo.

      No apology needed being new to all this. You might want to get the companion books: the 2019 udpated revision of Stop the Thyroid Madness and Hashimoto’s: Taming the Beast. Here’s good info about them: https://stopthethyroidmadness.com/2019/05/30/two-new-books/

      Reply
      • Dedee

        Paltry – YES, I don’t think it’s doing anything and I feel like my thyroid is disintegrating within me! Very odd sensations and no one seems to understand or perhaps, really care?Some doctors think I’m nuts – they don’t say it, but the way they placate me makes it very clear. From what I’ve read on your site, people feel some improvement when they get the right dose and they reach the “optimal” levels of T3 and T4. I remain hopeful as I work through all of the information. This new development with the NP has me a bit concerned – as it took some convincing to get the NDT rather than Levothyroxine. I don’t want the dr. to say there are too many problems and just try to switch me back to Levo.

        I’m ordering STTM and HTTB now. (did I get the acronyms correct? ;)) I’ll start reading and share information with my doctor to convince her I need to take a higher dose and get tested regularly.
        I’m grateful for you and the members of this community. Thank you. 🙂

        Reply
  215. Issa

    Please also say how you are taking the NP tablet, ie, sublingual, swallow whole, crush. I remember that one problem with Armour was with a new pill making company that had harder ‘packing’ equipment. The new pills were so hard they weren’t dissolving completely as they went through the body. Hence, the hypo experience. Armour was saying, correctly, that they had not changed the formula. It took them awhile to figure out what was wrong because the pills looked and tested the same. The pictures seem to show that one of those pills could be packed harder. These pills are expensive, I will try crushing them to see if they work better if I get any of them. So far mine are the same. BTW I ‘chew’ mine a little to break them up and then let them dissolve under my tongue.

    Also, are these problems being reported with all the strengths? I’m hoping it’s a manufacturing problem because I really love my NP!

    Reply
    • Janie Bowthorpe

      Let us know what chewing the changed tablets does for you after you redo the frees. I know you said you are still currently on the former tablets.

      We haven’t figured out yet if the change happened to all the different strengths.

      Reply
      • Donna

        I think we need to prepare a form letter/petition and disseminate it to our local politicians, demanding that we not be forced to use Synthroid and that they investigate why all these changes and whatever are being made to NDT meds that have been reputable in the past and seem to be being sabotaged.

        Reply
        • Dedee

          You raise a valid concern, Donna. Big Pharma may not want the NDT on the market competing with their own products. Even a quick scan of internet sites discussing Levothyroxine raises doubts about the efficacy of generics, which plays right into this same suspicion about the influence of Big Pharma on the FDA and policymakers.

          https://www.verywellhealth.com/levothyroxine-brand-name-vs-generic-versions-1124055

          Reply
        • housemaid

          Donna, I agree it seems like there is some sort of sabotage going on, especially since CVS started refusing to sell natural dessicated thyroid. However, politicians are in the pocket of Big Pharma. They will always look out for those who give them money and not you, the consumer. It is best not to talk to the FDA or politicians about NDT not working or they will be quick to ban it and make everybody take Synthroid.

          Reply
  216. Andrea no

    I have been on ERFA since the last time. Big pharma messed with Armour. It’s currently unavailable. Wonder what’s going on now.
    My doctor switched me to Armour which I could not take due to the fillers. New formulation. New company.
    I was switched to NP thyroid about three weeks ago. I had to take a larger dose at the end of ERFA and now on NP. This raises questions aftet reading this. I was on the same dose of ETFA for many years. Now larger dose on both meds. Egad!

    Reply
  217. Leora Hyman

    So terrible .I was feeling better on Naturthroid and my hair was better. Then it went south. I’m now on synthetic T3 and T4. Still a process….

    Reply
    • Janie Bowthorpe

      A process is a good way to describe all this. Yet, even on the two synthetics, we have to get optimal to prevent hypo symptoms from returning. Optimal puts the free T3 towards the top part of the range and the free T4 midrange. Both. And we have to have good cortisol and iron to get there without problems.

      Reply
  218. Heidi Salerno

    I filled 120mg and 30mg and they smell awful. I’m not optimal so I can’t comment on that. But the smell has been causing an aversion to them.

    Reply
  219. Brittney

    I can’t believe this! I’ve felt awful most of my life and just have been optimal and healing my adrenals in the last several months. I hate being reliant on these drug companies. If they are just changing our medication without a care as to how it affects their customers, that is just evil.

    Reply
  220. janice

    Is there any particular pharmacy that still has the old stock or version of NP Thyroid. Is it certain milligrams? My 30 mg taste differnt but my 15 mg. ones taste ok. Anyone else experience the same. Was wondering why I felt so terrible. Thought I was in a flare from my lupus. So damn fatigued again and lots of hairloss.

    Reply
    • Janie Bowthorpe

      Hi Janice. It’s really about local pharmacies. So where one chain might have it where you live, another might not. You’d need to call around.

      Make sure your fatigue and hair loss isn’t from being underdosed. We have to separate those who are underdosed from those who are optimal yet still went downhill on the new tablets. Optimal puts the free T3 at the top of the range and free T4 midrange. Both.

      Reply
    • AnaG

      Wow this is just in time
      I too noticed a smell in my last refill oh NP Thyroid abd after morethst 15 years on NDT I decided to switch to synthetic just this week. I was not feeling well, i a mi in a deep fog and my weight is stuck at the top of my range. I feel bloated and uncomfortable.

      Not sure if my choice of genetic synthetic is the best but will give it a try for a week or so. My body reacts pretty quickly…

      So grateful for your blog

      Reply
      • Janie Bowthorpe

        Just make SURE you are optimal no matter what you are on. Over the years, we have noticed that hypo symptoms will eventually come back due to not being optimal. In other words, we have to be on a dose that is meeting our daily needs over and over. Non optimal doses eventually backfire. Optimal puts the free T3 towards the top part of the range with a midrange T4–both. And we have to have good iron and cortisol to get there without problems.

        Reply
  221. Betty

    The Doctor told me to reduce my np because I was taking too much. I was on 120 and 15. I still have a bottle of the 120 left and I was sent a new bottle of 120. I just now went and look. You are so right. They have a weak smell to me. I have not taken any since I still have about 75 of the old ones left. I hate this. I was on armour for years and changed to nature throid. I was doing great on it and than they changed it. I went on np about two years ago and felt great and now I may start getting worse again. Why can’t they just leave a good thing alone. Thanks for telling us.

    Reply
  222. Joy Rainwater

    I don’t know if I ever got to optimal on NP Thyroid. I take a 120 mg dose, when I go to refill my prescription, the pharmacy says it’s on back order. I have been taking 2 60 mg tablets. I did notice more of a smell. I live in Athens, TX

    Reply
  223. Jessica

    This is so frustrating. Was doing well on 60mg for two years (don’t have recent labs but dose and symptoms haven’t changed) and then got the nasty tasting ones two weeks ago… now exhausted, hair falling out in gobs, stomach issues.

    I’m going to call Acella again tomorrow.

    Reply
  224. Pilan Butts

    Janie,

    Re 2018 recall

    Maybe they are trying to get rid of last years batch at a lower price and pharmacies are selling it.

    https://www.fda.gov/drugs/drug-safety-and-availability/fda-alerts-drug-makers-recall-porcine-thyroid-api-sichuan-friendly-pharmaceutical-co-limited-china

    Reply
  225. Pat Boatman

    So what are you suggesting we do if those that aren’t optimal now that has been optimal in the past? The state I’m in has very few options for us. Endocrinologist are clueless. I’ve been to 6 and they go by blood work and tsh. Forget symptoms. Idiots

    Reply
  226. Pat Boatman

    So what are you suggesting we do if those that aren’t optimal now that has been optimal in the past? Mississippi has very little options for us. Endocrinologist are clueless. I’ve been to 6 and they go by blood work and tsh. Forget symptoms. Idiots

    Reply
    • Janie Bowthorpe

      The next step seems to be to check the frees, then raise if not optimal. And let us know. We can just hope that it’s now far weaker and raising is needed. Sad, though.

      Reply
  227. Linda Schneider

    I switched to compounded Armour after they changed it several years ago and I had been sick for a year and a half. I feel so bad for all of you…I just wonder, it seems to me that lying about the ingredients in something we injest, isnt that against the law? Like say, what if you have allergies to rice and they change and add that as a filler, wouldn’t it be against the law to lie about it? I mean, it could kill someone that was allergic to rice. I wonder if they are using the same ingredients but making the dosage different…? How is this even legal…?

    Reply
  228. Traci

    I concur. Picked up my 90mg NP refill over 2 weeks ago (I take 2 twice a day and have been optimal for 6 months). I gagged when I took the first tablet. Appearance was different and I knew something was off. Left a message for Acella’s Quality Department but never received a response. Trying to decide whether I’m going to have to switch. My hypo symptoms have returned and my hair is falling out. I KNOW they are a different formulation

    Reply
  229. Jennifer

    What are our options if NP is now bad? There’s nothing left to chose from. Do we have to go back to synthetic? This is so horrible.

    Reply
    • Janie Bowthorpe

      Honestly, things are suspicious, but we have to separate those who were optimal before getting on the changed tablets, and those who weren’t. Those who weren’t optimal will not be strong indications that something is wrong. Because by being underdosed, it always backfires with a return of hypo.

      But if someone WAS optimal before starting on the changed tablets, and still report a decline, that is very suspicious. We need to see more.

      Reply
  230. Pat Boatman

    I live in Mississippi . I’m 67. Have had a renal embolism 3 yrs ago and lost a kidney. I see a internal medicine Dr. My free t4 and free t3 are below optimal. And this Dr says he’s trying to help me live longer.ugh. But I haven’t felt that bad inb2 grains of NP a day so just left it at that. But have been feeling symptomatic lately and complaining. He just ordered my sex hormones level . I’ve picked up 10 pounds this yr and can’t seem to loose it no matter what.
    I have noticed I feel no different if. Take 3 grains instead of 2. That has surprised me. .now I’m wondering if it’s. A weaker dosage per grain?

    Reply
    • Janie Bowthorpe

      If you have been underdosed, we can’t blame the changed tablets. It’s normal to feel good at first even when underdosed. But it will eventually cause a return of hypo symptoms if underdosed.

      Reply
  231. Judy

    Yes, I got a refill of 2 grain and 1/2 grain tablets a few days ago. I immediately noticed that the color and smell are different in both bottles. It smells like a completely different product. (I took side-by-side photos of previous and current refills, and I can send those to you, Janie, if you tell me where to send them. In those photos it’s very very obvious that the pills look completely different from each other. The previous refill looks yellowish, whereas the new looks slightly pinkish gray and speckled.) The taste is also different.

    So on Monday I called Acella, and the person I spoke with said they hadn’t changed the formula and that there can be differences in color and smell from lot to lot. I was very glad to see you discussing this today, Janie. Where have people been talking about this? FB or Yahoo groups? The Walgreens pharmacist also wasn’t aware of any changes or differences. UGH.

    The Walgreens pharmacist also made a comment about the med being from pigs, and the way she said it was rather rude. Other pharamacists have talked to me that way too. They act like ti’s so weird or gross, maybe implying that whoever takes a medication like that must be weird. What choice do we have? It’s a medication we have to take to be alive and functioning normally. For many people, nothing works anywhere near as well as NDT. I think if those people who act like it’s weird were in a similar position, they would take porcine thyroid too, if it’s a choice between being alive and functioning and other alternatives.

    Also I’ve changed meds 5 times (synthetic T4/T3, WP, NP, synthetic T3 plus various thyroid nutritional supplements) since Women’s International compounded was recalled almost a year ago. Nothing works for me as well as compounded did, for many years, although NP has worked about the best (in addition to several thyroid nutritional supplements) of anything I’ve tried since the recall. When NP wasn’t working that great for me earlier this year, my dr said, based on symptoms and labs, that maybe I wasn’t converting T4 to T3. So he prescribed T3 in addition to NP, but I quickly had various side effects. So I had to stop taking that. After that I started taking the various nutritional supplements that are helping.

    I called Women’s International yesterday to check on status, and they still can’t get raw material and have no idea when they will be able to get it. They also express little compassion or concern. Very sad since compounded had worked great for me since the Naturethroid sudden shortage happened in 2009.

    It’s all very discouraging. If NP goes haywire and that stops working for me, I don’t have any other options, since I’ve already tried just about everything else and it hasn’t worked. Or what alternatives do people have, if NP stops working? What’s the latest info on WP? Is that working for people?

    By the way, Janie, did you say that toxic mold exposure caused you to have thyroid problems in the first place? If so, how did you figure that out, and was the damage permanent, or is it possible to reverse the damage such as through detoxing and repairing?

    Reply
    • Janie Bowthorpe

      Yes, I did finally realize that my exposure to mold (master bedroom closet would get mold on my shoes constantly) probably caused my hypo. If I had known that then, maybe I could have reversed it. Not sure. Mold is very damaging. And I’ve been on thyroid meds so long now that my thyroid has probably shrunk to nothing.

      Reply
      • Judy

        I think mold contributed to causing hypo for me too, or maybe it was the only cause. Was living in a moldy place when diagnosed hypo. A dr told me that I have mycotoxins (mold toxins) in my liver and that’s affecting my thyroid. That’s logical, if for example mycotoxins in the liver are affecting the T4 to T3 conversion. I’ve been hearing lately of more and more people who say mold exposure caused them to have hypo. The thyroid is so sensitive to so many things. Yes it seems that if hypo is caught early, it’s easier to reverse it, from what I’ve learned. But it’s still possible to be helped even later too.

        Reply
  232. Hadassah

    Janie this is Very Concerning to all of us on NDT . I was on T4 only and was having so many issues . I started with NatureThroid and it worked great for me till RLC reformulated . Even with all their denials . Who do they think they are fooling ? I switched to NP and it worked well . Janie I know that you mentioned that you dose with NP and that your very happy with it . I now wonder what are your thoughts about NP ? And what is the next NDT that we can trust to feel well with . Unfortunately we are running out of NDT . And the very few that are still around are not reliable .

    Reply
    • Janie Bowthorpe

      I am still using the former NP. So I personally haven’t experienced a problem. But we need to separate those who were NOT optimal before getting on the changed tablets, from those who WERE optimal before getting on the changed tablets and who saw a return of hypo afterwards. It’s the latter which will be a great concern.

      Reply
      • Judy

        Janie, everyone who takes NP needs to look at and smell their tablets to see if they’ve noticed a change in the medication. Is there a way to do a survey of people who take NP to be able to really get some definitive info and sort all this out? And ask questions like:
        when did you start taking NP thyroid? what was your dosage?
        what is your current dosage, and when did you start taking that dosage?
        per your labs and symptoms, were you optimal on NP, and if so, when and for how long?
        have you noticed a change in the smell, appearance, or taste of NP?
        if so, when did you notice a change (what was the date of NP refill)?
        have you noticed an increase in hypo symptoms while taking NP, and if so, when, and how did the timing of symptom increase match up with change in appearance, smell, taste of NP?

        Reply
    • Hadassah

      Janie I’m also still on the old batch myself . But I worry when I run out of it what then ??? What I don’t understand is if so many are on NDT and are doing so well with it why are they playing around with our NDT ??? Where lies the problem ??? And Why ??? I’m sure it’s a Huge Money maker for the companies at our expense . If we stop buying they can all close shop . I’m wondering why would they risk it ??? And who is out to gain from all this ???

      Reply
      • Janie Bowthorpe

        Your questions are good ones. It’s just crazy about these changes. And the secrecy as to why the changes, and denying changes, is a bit off-putting to our experiences and intelligence.

        Reply
  233. Deanna

    I am also taking NP Thyroid and now feeling extremely tired. What is a better brand to take?

    Reply
    • Janie Bowthorpe

      Deanna, have you possibly been underdosed? If your free T3 wasn’t at the top part of the range with a midrange free T4, you were underdosed. And being underdosed always backfires with a return of hypo symptoms sooner or later.

      Reply
  234. Kristine

    I’m hoping that they’re just slightly weak, as I’m not feeling horrible on NP. I did notice the change in taste. It’s nasty but I’m able to do sublingual still. I thought my food cravings and weight gain was stress or my lack of control. Now I wonder if it’s something else.

    I take a relatively low dose, just 75mg. We’re trying to resolve the inflammation and high rT3. No antibodies. I’ll try increasing a little to see if that brings me back to where I was a few months ago.

    Reply
  235. Sharen

    Yes, sad to say I am experiencing the same thing with regards to being optimal and feeling great. I have been on natural thyroid since thyroid removed in 2001 so I have been through all the changes. Now all symptoms back with labs not optimal at all. It does remind me of the debacle with armour where I became terribly ill until I found out they had changed and then went on Naturethroid. Switched to NP Thyroid when Naturethroid not available. Labs were optimal and I felt great until after I picked up my new RX I began feeling tired again. Digestive issues. Brain fog. Anxiety. Depression. Hair falling out. I said to myself that this seemed like when Armour was changed. I looked on your website and tried to find information if they had changed their formula but found nothing. As I thought my latest labs showed NP certainly not working at all for me. May be for some people. Quite discouraging. I may have to order from Thailand and do my own labs as my holistic doctor will not allow that. You can order without RX. Thanks for the update.

    Reply
  236. Peggy

    Oh my gosh! I’ve been trying to figure out why I’m back to feeling like crap! I had noticed the horrible smell and taste, but never put it all together. This is just shy of devastating. Trying to feel normal has become a full time job!

    Reply
    • Janie Bowthorpe

      Peggy, were you doing great for a long time before you started on the new tablets? Were you OPTIMAL before starting on the new tablets (free T3 towards the top; free T4 midrange–both)??

      Reply
      • Peggy

        No, I wasn’t optimal yet, but was getting there, then I could tell something had changed with the smell, taste, and feeling extra fatigued and painful.

        Reply
        • Janie Bowthorpe

          That’s good enough proof. There was no reason for you to feel extra fatigued and painful upon starting the changed tablets. We are totally convinced they are messed up.

          Reply
  237. Terrie Radachowsky

    I just had to WAIT for Walmart to refill my NDT.
    When I received the script, I thought they had given me the wrong prescription.
    It smells, tastes wrong and makes my stomach
    Yucky. So I goggled to see if there was a reformulation and found nothing.
    I have been on the rollercoaster of reformulations for over 12 years now, Armour, Erfa, ….now NDT. Although, i have been optimal for a long time with dedication and monitoring.
    I haven’t noticed symptoms yet but now I know that something is up and why.
    As for the companies denying the changes, who can even guess. The FDA is understaffed, staffed with campaign workers and a mess.
    I now wonder where can I go from here?
    What other options are there?
    It should be this hard to keep a person’s health .

    Reply
    • Janie Bowthorpe

      Yes, it’s a bit of nightmare to find a product that has been masterfully changing lives, only to see this mess with so many NDTs. The number one question is WHY. And WHAT has been going on. The secrecy is insulting.

      Reply
      • Pilan Butts

        Im thinking nefarious reasons. There is to much going on and multiple brands involved. Maybe to many people are doing well and big pharma put the squeeze on fda made them change the way its made that would alter its great performance. Levo probably suffering from ndt being so successful. Just a wild guess.

        Reply
  238. Barb Collins

    I got my NP Thyroid refill a week ago, I took it back to the pharmacy because I thought they had given me the wrong med. Nope they told me it was the same as I had been getting. My problem is I am very sensitive to the fillers that they use. I had been taking WP Thyroid and was doing great, then I had to switch to Naturethroid and my levels tanked. I then went to NP Thyroid and was feeling great for the first time this year. I haven’t even taken this new one for a week and I feel terrible. It definitely has been changed. I absolutely cannot do Armour. I guess I will go back to WP Thyroid. Does anybody know if it WP is any good since it has come back?

    Reply
  239. Marty Gerace

    With all these changes just wanted to say that after a year of not being able to get NDT powder (which I had compounded for many years). I was finally able to find it in PA, where they are compounding in one drop olive oil. I am hoping this will help. Have been on synthetic compounded, doubled my dose and my TSH came back 69.7. Not good. Bad indigestion, back pain, exhausted, awake at 4am, anxious, depressed. Hope this works. Fearful it may disappear again if it does work.

    Reply
  240. Nicole

    So that explains everything. I gained all of the weight back from when I first lost it after being treated in the first place. And my antibodies are the highest they have been since initial diagnosis even with NDT, which usually keeps things in check. I also had dialed back the dose with my provider because we are doing root cause digging, but I feel dreadful. Now I know why. I had even switched back from Armour because I felt so good on NP last time.

    Reply
  241. Yvonne

    Yes, meeeee tooooo! I do not have a thyroid but I was optimal on NP Thyroid until my last prescription of 90mg (2 per day). When I went for labs last week my free T3 was bottomed out and my T4(total) and free T4 were also at the way bottom of normal range, yet my TSH is suppressed (whatever!). I was VERY confused but it all makes sense now…hair falling out, feeling confused/loopy, feeling extra tired. My doctor is switching me to branded Synthroid and Cytomel. I hope I feel better — is there any brand of NDT that is still good?

    Reply
  242. Jill

    I was on NP and doing ok this year. Approximately 2 months ago I felt strangely tired & odd, & the last rx from Walgreens smelled absolutely rancid… really gross and alarming. ( Despite it being a pork product, the smell was NOT normal). I got my dr to switch me to Nature-throid, because I *thought* Nature-thyroid was more reliable (?!), and because my other dr wanted me to have narcolepsy testing…. because I am beyond sleepy. I realize, of course, that is likely a thyroid issue. So, anyway, I’m unable to function. My local dr has no real knowledge of thyroid issues..he still does TSH testing, sheesh. My brainfog is glaringly obvious and I feel stuck..have put on at least 15 lb overall, am lethargic, hair thinning, puffy face…feel just awful! If it hadn’t been for the email I received from here, I would still be in self-blame mode, wondering if I had some sort of virus! I am not sure what to do now. Is Naturethroid useless, too, now? I order mine from a pharmacy in California… it wasn’t easy to find. Thank you for this information, I really appreciate it. But I really don’t know what to do next. Thanks!

    Reply
    • Janie Bowthorpe

      Synthetic T4 with synthetic T3 if raising doesn’t help. Raising is always an optimal to see what happens while watching the free T3 and free T4.

      Reply
    • Janie Bowthorpe

      Yes, there have been many many reports that Naturethroid went south, too. And like the other pharms, they deny changing anything.

      Patients on the changed NP can always try raising and see what happens, watching the frees. Otherwise, synthetic T4 with synthetic T3.

      Reply
      • Dawn Volz

        Janie I spoke to someone regarding Naturethroid when things changed. They told me that due to cost they switched to a different supplier of desiccated product. I told them many were finding it inferior. I was told recently that it is now impossible to find in pharmacy. I wonder if they will go back to old supplier? They said the product had become very costly that is reason for the change in supplier.

        Reply
        • Janie Bowthorpe

          i.e. the cost of the good supply would have lowered their profit. Sad, because if they had stuck with a known good supply and thus product, patients wouldn’t have left them behind in the dust…which has surely lowered their profit anyway.

          Reply
  243. Bonnie Rasmussen

    Hello I live in Houston Texas!I just picked up my NP thyroid Monday and it looks and smells exactly the same as it always has. I switched to NP thyroid about a year ago after Nature throid went south. Where are y’all getting these pills from??? What’s your location and/or which pharmacies are these bad pills coming from? I got my labs done on July 5th and they were the best I’ve ever had. TSH 1.04, t4 3.3 t3 uptake percentage 35% and free thyroxine 1.2. I hope this is just a bad batch of NP circulating and not a permanent change. I just can’t go through that again.

    Reply
    • Bonnie Rasmussen

      🤦‍♀️Oh no I spoke too soon. I picked up my new np dose Monday and my 120mg look the same but my 60mg are totally different, smell, taste even the way they dissolve under my tongue is different (I take 180mg a day, my job is extremely active). I have been having some stomachs issues over the past couple days. I just feel gassy, bloated. My stomachs is very sensitive I do not eat grains, gluten, dairy, soy, eggs or nuts because I can not tolerate them so I have been confused by my stomachs pain because my diet is exactly the same as it has been. What we do now? Am I just supposed to wait until I’m hypo???? What are my options??? How do I get get a compounded medication? Do I need to ask my endo for a different script?? Is compounded more consistent???

      Reply
    • Janie Bowthorpe

      We hope so too that it’s a bad batch circulating around. This is nuts.

      Reply
      • Alex

        Janie, would be this not useful if everyone who feels bad on „new“ NP would post here the batch number? I wrote already last year, that one bottle of NP stinks and has a bad taste… Since then taking NP I was getting so bad so that I thought I will die. However I was for many years so happy with NP. I was on 3,5 grain. First I thought I am underdosed so I increased and increased my dose. I felt more and more worser… really seriously ill….What happens to all NDT? What should we do now?

        Reply
        • Janie Bowthorpe

          Hi. Yes, maybe they will see this and post the batch number. I can add it to the post.

          So far, we don’t know yet if the changed NP tablets won’t work if we raise. So some could do labs while on it, then try raising, then do labs again after a few weeks, then report back.

          Reply
    • Pat Boatman

      I live in Mississippi and use Kroger. Think I’m going to call around to see where a few other pharmacies order from. Will switch if they get from a different company

      Reply
  244. donna cason

    Talk was going on about this for several months now…correct? Do we have an approximate time that this started or is that hard to figure out. I have 60mg and just picked up more…the smell is no worse than normal to me (and I have had some nasty smelling NDT….which I still took). The appearance is normal and not ragged. I am optimized now but I am tired but that could be because I don’t sleep well (3am wake ups). But maybe it is from the NP? What to try next?

    Reply
    • Janie Bowthorpe

      Comments were trickling in around early summer, but nothing like they are now.

      You may have picked up the former stock of 60 mg NP. Yes, your feeling tired could because of waking up, and waking up could be because of adrenals.

      Reply
      • Donna Cason

        But I am on HC and have been for 11 months so that should not be…just started weaning.

        Reply
        • Janie Bowthorpe

          Probably not a good idea to wean if on the changed tablets, since the latter have been causing a return of hypo symptoms in those who were optimal before they got on the changed tablet.

          Reply
    • Liz

      I almost posted the other day asking if I’m the only one that’s noticed a change since I received my last refill. I take 4 60 mg tabs a day, no thyroid, treated iron and adrenals and finally was doing good and steadily weight was coming off. I have been taking my last refill for about a month now, and when I first opened it noticed the horrid smell, tasted different too. Anyway, the last couple of weeks I’ve felt really fatigued, low energy, hungry all the time, weight creeping back up and bloated. I use express scripts pharmacy to fill my meds. My 11 year old son also takes NP 60mg plus 30mg tabs daily (completely underdosed and still terribly hypo but that’s another story). His refill was delivered today so will see what it’s like when we open it.

      Reply
      • Janie Bowthorpe

        Now YOU are what we need to hear about. You seemed to have been quite optimal, yet on the changed tablets, bam…you have gone downhill. That seems to be a strong indication that something is quite wrong with the changed NP tablets being wonky. May I add your paragraph to the blog post??

        Reply
  245. Peter Goodwin

    Sounds very much like a class action suit in the making.

    Reply
  246. Jeni

    I noticed they smelled and looked different – so much so that I double checked the rx description on the bottle. The taste was unbearable. I’ve been taking sublinguilly for years and suddenly must swallow them whole. The last two weeks (since I refilled my rx of 60mg pills), I have been going downhill with many symptoms returning. I have been fine for 2 years on this dose, so it seems odd that I tanked so fast.

    Reply
  247. Amber McCullough

    I can not believe that we are once again dealing with this issue. Changed from naturethroid to NP and was ecstatic in the beginning. In the last month, with my new script I have been feeling that tired to the core feeling again. My hair has been falling out as well. My daughter who is also on 2 grains is constantly napping. It never dawned on me that they could have reformulated, but definitely seems so. I also have been extremely brain fogged too. I pray we find a thyroid med that doesn’t change and can give us our lives back.

    Reply
    • Janie Bowthorpe

      FYI: 2 grains may be underdosing your daughter. It has for the majority. She needs to check her free’s. Optimal posts the free T3 towards the top part of the range and free T4 midrange. Both.

      Reply
  248. Rose Helia

    I have been taking Naturthroid for years now. Since the Erfa product went bad. I wish I had never switched myself to NDT. I was find on levothyroxine. I only switched because I lived with a woman who subscribe to newsletters from Dr Whittaker. He insisted that NDT was better. So I switched for NO REASON. I was NOT having problems. Now, I cannot go back. And NDT is a regular headache. When Naturthroid became unavailable, I thought I was going to get it from a Walmart pharmacy when Walgreens couldn’t get it. Turned out what I had gotten was Armor, even though they CALLED it Naturthroid. It cost me 15 lbs. and some serious mood swings before I realized I was NOT taking Naturthroid. I called my endo and she told me I needed to order Naturthroid through mail order. That has helped. But it is 4 times more expensive this way. Sometime, I might try a slow switch back to levothyroxine. It worked before. And it just seems like a matter of time before Naturthroid gets messed up. You say it is already messed up. But I did not notice it failing on me… ????

    Reply
    • Janie Bowthorpe

      Honestly, Rose, most people on Levo, even those who think they are doing well, either aren’t and don’t recognize the symptoms of a poor treatment, or see a decline sooner or later. There is simply too much that can cause problems with T4 converting to T3. We need direct T3.

      Reply
  249. Roberta

    I recently changed from Armour to NP thyroid. Feeling horrible, all symptoms back, gained 5kg in just one month. That explains everything!!!!!

    Reply
    • Gala

      I was thinking of switching from armour because I feel hypo I’ve taken amour for 9 yrs 180mgs but I hear so many bad things about all of the ndt from time to time scary because we depend on NDT to feel normal where to turn now..??

      Reply
    • Nicole

      15 lbs in 3 months. It’s dreadful. And my antibodies are through the roof… even on NDT. Ugh!!!!!

      Reply
      • Janie Bowthorpe

        Were you optimal all this time on NP? Optimal puts the free T3 towards the top part of the range and free T4 midrange. Both. We need to separate those who weren’t optimal (which causes a return of hypo) with those who were optimal (and are seeing problems).

        Reply
  250. Kari

    My NP was increased to 90 in April, I felt amazing within 10 days! My last rx I picked up on 8-5-19 I noticed a color changed and have been exhausted the last 10-14 days. I cannot get enough sleep, achy, and depressed feeling.

    Reply
    • Janie Bowthorpe

      There is a possibility that you are simply experiencing the effects of being underdosed. Underdosing always backfires. Most of us when optimal are far higher than 90 mg. The way to get optimal is test the free’s we have found. Optimal puts the free T3 towards the top of the range and free T4 midrange. Both.

      Now my above comment doesn’t take away that others are seeing problems that weren’t there before!! So you may have a double whammy.

      Reply
      • Kari

        7-30-19 labs
        Free T4 .98 w/ range of .70-1.48
        Free T3 3.49 w/ range of 1.71-3.71

        This is when I felt great. Will try to get labs in the next couple days to see where they are now.

        Reply
        • Janie Bowthorpe

          Yes, we will always feel great before we get optimal. But it eventually backfires. Your FT4 is lower than it would be when optimal, implying you were underdosed and it was converting like mad to the free T3 you did have. Will be curious where you are today.

          Reply
        • Virginia

          Erfa Thyroid has changed as well. Used to be yellow, beige colour and tasteless. This month I started feeling terrible again (hypo) and then noticed the tasted was super sweet. I take capsules as my medication is compounded. I pulled the capsules apart and low and behold the powder is no longer yellow beige, it is bright fuschia pink!! Been dealing with this nonsense for 10 years +.

          Reply
  251. Sandy Budzik

    Thought my latest batch looked different but smell and taste seemed right. Mine say AP and 331 not 330 which would tell me something is a bit different!! Am not optimal so hard to say if is effecting me but have really been needing a nap almost every day and I am not a napper. Where do we go from here–what other options do we have????

    Reply
    • Janie Bowthorpe

      So the naps have occurred since you got on the changed tablets?

      I’m just hoping like heck they are simply weaker and we can raise and get the same previous effect.

      Reply
    • Janie Bowthorpe

      I would personally try raising and see what happens. Watch labs.

      Reply
      • Martha Stalcup

        The tablet with AP 331 imprint is 90mg, while the tab with AP 330 is 60mg – so there’s that difference!

        Reply
    • Dee

      I was doing great on old ERFA but when they changed it to new ERFA that was one of my symptoms. I would take one and basically just want to go to bed and pass out almost. Just one of the symptoms!

      Reply
  252. Kate

    After being undertreated because of the new Naturethroid, I switched to NP and began feeling much better. Then I got a stinky batch of NP 120 at the end of May, and assumed it was stinky pigs or summer heat during shipping and didnt even worry about it. In July, I started feeling quite drained and had anxiety issues which I attributed to summer heat and busyness. Just had labs drawn and I am low on everything except TSH. Very frustrated.

    Reply
    • Janie Bowthorpe

      Oh gosh. That sure does seem to point to the changed NP. Ugh.

      Reply
      • Deb Quinn

        Maybe big pharma has something to do with it. Nothing surprises me anymore.

        Reply
        • Janie Bowthorpe

          Well, “big pharma” just means all the pharmaceuticals collectively. And it doesn’t fit that they would shoot themselves in the foot by ruining a product that makes them money. But the FDA is a whole other ballgame here that may be the problem. But who knows. The most frustrating aspect of all this is that we are treated like children who should never, ever know the truth as to what is going on. It’s condescending and irritating.

          Reply
  253. Nadine

    I’ve had a stiff neck for 3 weeks but I thought it was because of a massage I got. The last time this happened was in 2015 with WP. I hope this is just a bad batch of 120mg NP. UGH!

    Reply
  254. Patricia Brannon

    I picked up my recent refills & started the new 60mg on 7/27. Within 3-4 days I felt horrible & for that week I was like WTH happened? Then I remembered my new script & how this is exactly how I felt when WP, ERFA & Armour changed their formula or manufacturing process even though they all denied any changes. I was taking 75mg (60mg & 15mg). I was actually feeling really good for the 1st time in a long time as I was also supplementing my 75mg a day with 25mg of a non prescription NDT & taking my vitamins on a regular basis. 2 steps forward 10 steps backwards. NP Was the last holdout for the changes the USP has been making to the way porcine desiccated Thyroid is processed. I have always said this goes way back to 2009 when there was a huge swine flu outbreak & I personally believe the USP/FDA decided to step in on NDT’s which were grandfathered into the Pharmacological system since the early 1900’s.

    Reply
    • Janie Bowthorpe

      Hi. Do you know something I don’t? i.e. this: “…changes the USP has been making to the way porcine desiccated Thyroid is processed.” Have you read that somewhere?

      Reply
      • Patricia Brannon

        Janie, Yes back in 2017 when RLC Labs went short on WP & Natur-Throid I did a ton of research & found some interesting info on the UPS’s website. I will have to search again, as I don’t remember exactly what it was 2 years later & having issues with severe brain fog with NP right now! I don’t know if you noticed all the prescribing info documents like the one found on NP Thyroids website say “(Thyroid Tablets, USP)” which was not there before, if I remember correctly. Unfortunately I don’t have an older copy of the prescribing info page to compare it to.

        Ok so if you look back at your page on “Thyroid Medications (NDT, T3, etc)” ingredients it shows 4 inactive ingredients. If you look at the new prescribing info sheet from Acellas website there are now only 3, with Maltodextrin removed. Steve from Acella specifically told me in a phone conversation last week that he was not aware of any formula changes. Ya, right!

        Reply
    • Angie F.

      Here’s my experience with my last refill (I have a new refill that I have yet to pick up). Felt hyPER for a month or so with a higher T3, and a bit lower T4 on a lowered dose. Could have been temporarily pooling due to life stress..did not notice any change in taste, smell or tablet consistency or texture. Both batches say AP on one side and 327 on the other (15 mg football shaped tablets) However had noticed toward the END of the fill, my usual suspect list of hyPO symptoms. Very low HR, constipation, edema, very tired in evening, hard to wake up, a frozen shoulder episode and more. Also some itchy eczema. Will report again on new batch after I pick it up.

      Reply
  255. Michelle

    I was in the process of switching from T3 only to NP. I felt great as I took the 30mg pills. No smell, no taste and I was feeling so much better than on T3 alone. My dose got high enough to switch to the 60 mg pills and I instantly noticed a difference in smell and taste. So much so I couldn’t put the pill under my tongue so I am swallowing the CR dose on an empty stomach. I have started feeling all of my symptoms come back again. I have gained weight, my pin has increased greatly, the tiredness has returned and the brain fog is much worse. I thought maybe it was just me until I started seeing other people ask about it. I was definitely not at my optimal dose yet but was continuing to raise without any weird effects.

    Reply
  256. Erica

    My 120 pills smell so bad. I have felt worse and symptoms are back again.

    Reply
    • Janie Bowthorpe

      Really sorry to read that. It’s just too bad that a GOOD NDT may have also gone south. Sure hoping that by raising these changed tablets, patients get better.

      Reply
  257. Kara

    My last three prescriptions have had a strong odor. I take the 60mg tablets. The past few weeks, I have been feeling drained. Coincidence? Ugh

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