Uh oh–we need to talk about NP Thyroid by Acella

Please note before reading the below: As you read the below, understand that we are in an exploration state in this horrendous new development. But there have been clear changes to NP which you will see once you read all the comments. Yes, there are patients who weren’t optimal before picking up the changed tablets, and yes, not being optimal can mean their symptoms were from that. BUT…we also have a lot of people who have gone noticeably downhill since starting the changed NP tablets, whether they were, or weren’t, optimal before starting on the changed tablets. We are SICK about this when NP was SUCH a good NDT.

SEE MORE DATED UPDATES AT THE BOTTOM OF THE POST. They will be posted as we get them.

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Thanks to patient Emily who took this photo. Former NP
pill on left; changed NP pill on right.

Comments have been coming in by some patients who are using NP Thyroid by Acella. And by those comments, it appears that NP has changed as of this summer 2019…as reported by patients who picked up a new bottle refill and started it. There are three common comments:

  1. It now smells and tastes horrible, worse then before.
  2. The tablets look different from previous ones
  3. I’m feeling much worse now on the same dose that made me feel great. Symptoms are back.

And it’s #3 that is especially concerning. .

This now makes FOUR natural desiccated thyroid products over the last few years that have changed visually and symptomatically. Why??

  • Canada’s version of NDT made by Erfa and called just Thyroid. That was followed by widespread reports of a return of hypo symptoms.
  • Armour after it was bought out from Forest and acquired by Activas Pharmaceuticals–many reported a huge return of their hypo
  • RLC’s Naturethroid, and it frankly went WAY downhill in effect in 2018 as expressed widespread by disappointed patients. We’re still not sure about WP.
  • NP Thyroid by Acella

And you know what else is common with all four pharmaceuticals?? They state “We changed nothing”. So what is going on?

ANALYZING THE COMPLAINTS ABOUT NP

THE SMELL, THE TASTE:

Ugh.

Yes, most NDT’s can smell. lol. It’s pork! But the reaction of patients, when they have started to take the “changed” NP Thyroid, is profound. “It tastes horrible!” “It smells far worse!” Other descriptions: “It tastes like insecticide.” “It tastes rancid.” “It makes me want to gag.”

Now we do know that a batch of NDT is made up of many pigs. And it’s possible that different mixes of pigs could produce different strength of smell. So is Acella using a particularly “stinky” batch of pigs now?? Maybe. Just the change in smell and taste is not indicative of a problem…

THE TABLET:

Boy, here we go again. The visual change is very similar to what we saw with Armour. It’s also similar with what we saw with Naturethroid. There are now specks on the newer current version, and some patients say the edges are rougher. Definitely a different color, too.

Former NP Thyroid tablet on left. Changed NP tablet on right.

In a way, these visual changes would be no big deal. But they could become a big deal when some patients, (who were optimal) are reporting a return of their hypothyroid symptoms and/or feeling awful since being on the changed NP Thyroid. And why is this not the first time that we started seeing specks in different pharmaceutical versions over recent few years?

FEELING WORSE SINCE BEING ON THE NEW TABLET:

This represents the most alarming of comments. We are seeing some people who were OPTIMAL and had been for a long while, only to comment that they now feel much worse since starting on the new tablets. Symptoms range from migraines, feeling tired, sluggish, feeling awful, depression, late afternoon fatigue, feeling like the flu, nausea, hair loss, napping again…etc. Again, we are saying some. Others report still feeling good. But are they on the “changed” tablets? Looks like they are. So we are continuing to try and learn what is going on in the face of pharmaceutical secrecy and the inane need to CHANGE what was already good enough.

Here is one of many examples of how patients are now going downhill on NP. It’s provided by permission from Liz: I take 4 60 mg tabs a day, no thyroid, treated iron and adrenals and finally was doing good and steadily weight was coming off. I have been taking my last refill for about a month now, and when I first opened it noticed the horrid smell, tasted different too. Anyway, the last couple of weeks I’ve felt really fatigued, low energy, hungry all the time, weight creeping back up and bloated.

And here is how one patient sees all this, closely resembling how many are feeling: I’ve had it with all the mystery, secrecy, deception, and lack of transparency that are ultimately badly damaging many, many people’s (mostly women’s) health and lives. And then that affects the lives of all those people’s families in a trickle-down domino effect. Those pharma companies and their associates are obviously not in it for any type of benevolent reason. They obviously don’t care about us. All they care about is money and their own interests. That’s sick (no pun intended), unethical, immoral, inhumane, and lacking in conscience.

In the meantime, for those who have gone downhill, these are options to consider:
1) [This initially suggested raising the changed NP tablets. It appears now that it’s not a viable option when the tablets have been making people so sick]
2) Crush the tablets before swallowing. One gal said she made the changed Armour tablets work this way. A sweetener of choice could be added to tolerate what is being described as a horrid taste
3) Move to Armour. Yes, it’s expensive and there are more fillers. And we just aren’t sure about it anymore.
4) Move to synthetic T3 with synthetic T4 (one grain of NP was 38 mcg T4 and 9 mcg T3 to help find the equivalent amount.) And remember we still have to be optimal even on both synthetics.
5) Move to over-the-counter NDT “supplements” No, we don’t really know how much of T4 and T3 are in them. It’s a matter of watching the labs free T3 and free T4 to find one’s optimal amount.

SO WE WANT TO HEAR FROM YOU, YOUR experience moving from the former good tablets and feel goods (those were were clearly optimal before the change are good gauges) to the newer tablets! Above you will see what “newer” is. And please, make it clear if you were OPTIMAL before you got on the new tablets (free T3 towards the top part of the range; free T4 midrange. Both.) or not. Lot numbers of your changed tablets are good information too, if you have it. Plus when you started on them. Etc.

AFTER you have read this post, and you know you have the changed tablets, go here to report on the lot number and/or expiration date. It’s just a way to figure things out. https://stopthethyroidmadness.com/2019/09/04/part-2-lot-numbers-or-expiration-dates/

The differences between the former tablets and new tablets. Thanks to thyroid patient Sara for allowing me to post this!!

UPDATE #1 on August 24th: So far, it appears that negative changes may have started in May, 2019 for some. But we don’t yet have proof that the changed tablets were coming out in May. We will continue watching for comments.

UPDATE #2 on August 26th: There are many reports about swine fever (not swine flu) killing plenty of pigs in China and into neighboring countries. Here is one. But that can end up being more about price increases. We still don’t have a definitive answer why the size of the NP pill changed, why the smell and taste is far worse, and why so many are seeing a return of their symptoms.

UPDATE #3 August 27th: A request has been made from Acella for the LOT NUMBERS of the CHANGED tablets…NOT the ones that are working.

UPDATE #4 September 13th: There is so much speculation and rumor out there as to why this has happened to NP Thyroid that it’s crazy. No matter what you hear, we do NOT know why this happened and NOTHING is concrete. On the good side, there does appear to be evidence from patients who are talking to Acella that Acella is looking into this. We can only hope.

Important note: STTM is an information-only site based on what many patients worldwide have reported in their treatment and wisdom over the years. This is not to be taken as personal medical advice, nor to replace a relationship with your doctor. By reading this information-only website, you take full responsibility for what you choose to do with this website's information or outcomes. See the Disclaimer and Terms of Use.

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1,247 Responses to “Uh oh–we need to talk about NP Thyroid by Acella”

  1. Sue R

    I am making the switch from NP Thyroid to synthetic starting tomorrow – Levoxyl and Sigma Pharm generic Cytomel. My last fill of NP Thyroid in October had less smell, but the smell is getting stronger over time. I’ve gone through the pain like everyone else – WP Thyroid to Naturethroid to NP Thyroid, all with their problems, which have caused my labs to be good and then bad. I’m tired of the game. I will have labs 6-8 weeks after the switch and will report back on how it is going. Fingers crossed this is the last time I have to switch brands! I am so thankful that my PCP was on board with this change and didn’t try to push T4 only. I am also grateful for Janie @ STTM who provides such valuable information and insight to all of us.

    Reply
  2. Tessa Osborne

    Just had a new supply of ERFA thyroid and which I have been on since 2011, and for the first time it smells funny and the tablets taste disgusting and, as I usually chew the tablets before swallowing, the taste really lingers. I’ve only just started taking them so haven’t noticed any change in symptoms yet. Last night I swallowed them whole as I couldn’t face the taste and the oily lingering flavour. Has anyone else noticed/reported this with ERFA . Its clearly been happening a while with NP.

    Reply
    • Janie Bowthorpe

      Hi. Did they for sure send you Erfa tablets and not NP Thyroid tablets? Because yes, what you are describing is exactly what is going on with NP. There are photos of each brand’s tablet on the net.

      Reply
      • marianne conlin

        On Np Thyroid 90mg, last Rx had a terrible smell and gave me a headache after 1 dose. I have switched back to Armour. Reported my experience to pharmacy and drug co.

        Reply
    • Angie F.

      Many patient complaints similar to yours at ERFA Canada Facebook page. This problem, across the board, appears to originate with the raw material. https://www.facebook.com/erfacanada2012/

      Reply
  3. Sandie

    I had tachycardia in May and started reducing my NP Thyroid from 120mg down to 90mg. Then I was still having palpitations and read here about the change and I had noticed the stink. Sooo frustrating to finally have my thyroid issues addressed a few years ago with NatureThroid and all of these changes. I kept reducing the NP until stopping at 75mg which seemed to halt the palpitations and I felt good. My labs were perfect – best they have ever been! I picked up my refill the other day a 60mg and 15mg and guess what? NO SMELL at all! So now I wonder if i will plummet into hypothyroid coma in a week or two?

    Reply
  4. Jacque

    How many hours should I not eat before and after my second dose of T3? I am also going to synthetic T4 and T3 from NP Thyroid. Thank you!

    Reply
    • Janie Bowthorpe

      You can eat with T3. It’s mostly calcium, iron, and estrogen….or even high fiber, that you want to avoid at the same time. So you could eat eggs, fruit, veggies, for example.

      Reply
  5. Rae Miller

    Picked up a partial order of NP Thyroid 60 at CVS (I take 2 per day), Bedford IN USA. Cat urine smell and taste. They don’t dissolve under the tongue– hard chunky pieces. After swallowing, the awful taste lingers in my throat and exudes into my breath when exhaling. Submitted lot number and exp date on the other thread here. I’m thinking of getting Armour instead; at least they aren’t disgusting. I have had to substitute one NP and one Armour per day for the past 3 weeks anyway, because of the difficulty in refilling my Rx locally. But this has always been a problem. The pharmacies never order it in a timely manner, even if I call early—so I always run out. I don’t know yet if I’ll have a bad effect from taking part Armour/all Armour. I don’t have much choice here of doctors who would be willing or knowledgeable to go with synthetic T4 and T3, so I’ll just hope for the best. This sucks!

    Reply
    • Janie Bowthorpe

      We’ve not seen people get optimal on Armour alone so far. And optimal has to do with what’s on they page: https://stopthethyroidmadness.com/optimal So you can try, and if not, it’s successfully to add T3 to Armour.

      Reply
      • Rae Miller

        My Oct labs didn’t test T3 Free. My May labs TSH (low .02 mcU/mL) T3 Free SerPlQN 4.5 pg/mL (1.5 -3.5 pg/mL), T4 Free Direct SerPl QN .7 ng/dL (.6 – 1.5 ng/dL) – (Oct labs this was .9 ng/dL). I feel OK energy wise but usually have afternoon sleepiness. I haven’t had access to DirectLabs for RT3 testing since I moved. Hashi’s, Sjogren’s since 2007. I have paroxysmal aFib once a month and sometimes more if my thyroid/ electrolyte levels are out of balance.

        Reply
  6. Tania

    Hi All
    Right Day ten on the new batch of bigger, super sweet NP Thyroid, after 6 happy years of brilliant, optimal labs, great BMI, and feeling good. i have a heart condition, pure FH which has led to CAD . Heart and lipids have been optimal too . and I’m Type 1 Diabetic. Great BS control.
    I’ve had ten days on the new batch and I now feel horrendous. Nauseous, migraine type headache, freezing, back to sleeping all night with electric blanket on full. Rapid weight LOSS….which is weird . Some adrenalin symptoms , which were a blast from the past …and TIRED !!!
    So, i have just been online and ordered Cytomel from the US. I have some Levothyroxine in. I was on 3 grains of NP, split into two doses. I have worked out my dose of Levothyroxine daily to be 120mcg…and 25 mcg of Cytomel, to match my dose of NP which i was optimal on. Now the big gun questions !!!!
    I feel crap now. I have a lowish/mid range T4 on NP anyway, totally suppressed TSH, and a near top of the range T3. Can I take the 120 MCG of Levothyroxine straightaway? Shall I take it tomorrow? I am a poor converter.

    Should I carry on taking the NP until the Cytomel comes from the US, which will take around ten days ? Should I carry on taking the crap NP along with the Levothyroxine, or may i over do things ?

    Is there a protocol to transition from NDT to synthetic T4 and T3 ? As it had to be done gradually the other way around . Or can I just take the equivalent dose of Synthetic T3 to that I have taken on NDT from the day it arrives?

    With having significant CAD, i don’t want to start any heart problems. I am in the UK, so have no Doctor to guide me with this, but to be honest I have been used to dealing with all this on my own for years now . Though i did have Dr Thierry Hertoghe all those years ago transition me originally onto Erfra, gradually. Since then I have changed doses etc on my own, and done my own blood work .

    I feel so lousy, i am tempted to at least start topping up with the Levothyroxine I have here, until the Cytomel arrives .
    Please, any advice.

    Reply
    • Janie Bowthorpe

      If T4 is low, might not hurt to top a little with Levo in my mind. Hope it all keeps you going until that cytomel arrives. It’s just too bad that a once excellent NDT has changed so badly.

      Reply
      • Tania

        Thank you Janie
        I’m starting to wonder if there is some Globalist conspiracy theory with all this . Why ??? Why ruin every avenue of treatment for so many of us who don’t convert the T4 to T3 endogenously . This morning I could hardly open my hands …they used to do tests for Capel Tunnel, Frozen Shoulder……all of these things went on NDT . So when I start to go Hypo, it makes my hands seize up over night. I think it’s fluid I accumulate. I slept through for 14 hours and could not get up !!
        I have a very physical job, i don’t know how I’ll cope ….anyway. Sorry for ranting I know many others are suffering too.
        So when the Cytomel comes I can switch straight over to those doses ? I will split the Cytomel into two doses . i used to take my full dose of Levo Thyroxine at 6 am to help my adrenals ….and no food.
        Do I have to leave a space between taking Cytomel and eating like with NDT ?
        Thanks for all your help people. x

        Reply
        • Janie Bowthorpe

          If you are going to straight T3, we general do it three times a day, approximately four hours apart due to it’s short half life. You can even add a very small amount at bedtime.

          If you are also on T4 for one dose, then twice a day for the T3.

          Find your right amount: https://stopthethyroidmadness.com/optimal

          Reply
          • tania

            I’ll be doing the Levo and T3 combo. so I’ll split the T3 dose, I’ll do bloods and see how i am. Trouble is in the UK now they only test TSH…No T4 or T3. But they always used to test my T4 at the lad because of my suppressed TSH on NDT. That used to blow their minds, thinking they had a Hyperhyroid patient, and then my T4 used to come back low/normal range. lol

          • Janie Bowthorpe

            You may have to self-order your FT3.

  7. Di

    Has anyone had experience with Woodland Hills Pharmacy compounded NDT?

    Reply
  8. Janet

    Just wanted to encourage those of you who are nervous about making the change to synthetic. I’m on 50 mcg name brand Synthroid and 5 mcg SigmaPharm generic Cytomel morning and afternoon (I was taking 1 1/4 grain NP Thyroid). The Mayne generic T3 was awful for me but I’m doing really well on this combination.

    I was able to ride my bike almost 15 miles today with no heart issues and good muscle endurance. That’s pretty amazing…in fact better than I was doing on the NP. Because I had done well on Thyrolar years ago I knew that a combination of synthetics would probably work, but finding the fillers I tolerated was a bit challenging. It’s hard to accept that likely our future options for NDT are going to be very limited, but I guess in a way I’m relieved to have made the switch just so I don’t have to go through this again and again when they mess with the manufacturing. I feel like every time there’s a black hole in my life until I get stabilized.

    Reply
    • Janie Bowthorpe

      That’s wonderful, Janet!! Really happy for you and glad you posted this.

      For others reading this, the small amount of T3 that Janet is taking wouldn’t do the trick for the vast majority. You might feel better at first, but it would backfire. So we dose to get optimal. Read this: https://stopthethyroidmadness.com/optimal

      Reply
    • Angie F.

      Janet..can you refresh my currently very hypo memory with regard to what your cardiac issues were? Thank you.

      Reply
      • Janet

        Angie, I have what is considered a progressive lung disease called Pulmonary Hypertension. The arteries in the lungs become constricted and sometimes scarred, in my case from a viral infection years ago. Because there is so much back pressure on the heart it eventually causes heart failure. Both hypo and hyperthyroid states are considered serious risk factors for worsening, so I have to be very careful to maintain the right dose.

        Reply
    • Ryan

      So you’re on 100mcgs of Synthroid, and 10mcgs of cytomel currently split into two doses? How pricing vs NP’s?

      Reply
      • Janet

        Ryan, my insurance is covering it for now so I’m not sure how much more it would cost. I do seem to be starting to react to the fillers in the SigmaPharm T3. That’s not unusual for me to develop an allergy to things like the other ingredients (in this case calcium sulfate dihydrate, corn starch, gelatin, magnesium stearate and mannitol), but I was hoping I’d be okay with it. So far still good with the name brand Synthroid ingredients. I may have to try the name brand Cytomel or get it compounded without any fillers and that won’t be covered by insurance.

        Reply
  9. Diane

    I am on 270 NP in a split dose. So far, so good.

    If I change to Armour, how much T3 should I ask my doctor to add?

    Thank you!!!

    Reply
  10. Teresa

    I was reading Mara’s list of ingredients in her digestive aid and noted that Ammonium Chloride is present. I wonder whether that could be the cause of the cat pee smell in NP’s disastrous pills. In checking the uses of Ammonium chloride, I came across this side effects list from rx list.com:
    “Rash, EEG abnormalities, Seizures, Mental confusion, Irritability, Drowsiness, Ammonia Toxicity symptoms (sweating, altered breathing, slow heart rate, irregular heartbeats, and coma), Calcium-deficient leading to tetany,
    Low blood potassium (hypokalemia), High chloride levels in the blood (hyperchloremia), Abdominal pain, Nausea/vomiting, Hyperventilation, Encephalopathy” Apparently it’s also used in cattle feed. Included in smelling salts because of the strong ammonia odor it emits, although some sources state that it’s odorless. Can’t determine why it would be used as an excipient in either Mara’s pills or the NP Thyroid pills. Of course these side effects might be caused by any number of other agents, but
    It would be useful to know whether Mara’s digestive pills have had Ammonium Chloride in them before this new batch….

    Reply
    • Mara

      I just got off the phone with Standard Process. They are going to test the batch that my digestive enzymes came from They say that the oder of Zypan changes from batch to batch and people often describe it as “foul”. The representative did tell me that the formula has changed. What was interested about that is the way the formula changed: they removed the lactose and substituted cellulose. However, I can’t imagine that the cellulose would be responsible for the cat pee odor. So perhaps it is the Ammonium Chloride. But my older bottle which does not smell like cat pee, also has ammonium chloride. The mystery continues…

      Reply
      • Teresa

        Thanks Mara! It’s probably not the Ammonium Chloride…it’s interesting that your bottle of digestive aid exhibits the familiar smell after a removal of lactose and substitution with MCC…I can’t imagine either that it would be responsible for the smell, unless it’s subject to interaction or decay.

        Reply
    • Karen

      When i looked up class two solvents amoniom chloride was listed in manufacturing of medicine. There is another comment on here about the FDA finding this as a violation in this plant making ndt. Very caustic agent.

      Reply
      • Jan P.

        Hi Janie,

        I take the 90 + 15 of the NP to equal 105mg daily. I Normally get 3 months worth, but this last August they had trouble getting the 90mg, so they gave me 60mg +30mg. I do have a few of the 90 left from May. My Doc also tried bumping me up to the 120mg in April, but I couldn’t tolerate it, so I do have about 20 days worth of that. In inspection of all these, I found that the 60mg is as described as being darker, and I let my husband do the unbiased smell test, he says it smells like cat pee as well.
        My question is, how do I find the lot numbers on all of these? Do I contact the pharmacy?

        My history is long and I really can’t compare like for like with others on this blog. I’ve been dealing with hypoactive Thyroid for 30 years now and went through hell of Synthroid and Levothyroxine, switched to Armour by a Jewish Doctor 😉about 24 years ago and was doing fantastic until the Armour change. Ended up with a different doctor, I finally found your website and was following everything closely. Went through having replacement compounded, where I sweared it was poisoning me. In 2014 had to change to an Endocrinologist and she was agreeable after a couple of weeks to let me try NP Thyroid, I went back and forth between Westhyroid and NP as the Pharmacist had problems getting it. So here’s the rub! 2016 I was diagnosed with Acute Myeloid Leukemia, and went through the hell of that. Went to Bone Marrow Transplant in March of 2017, however I’m now left with Graft vs Host Disease. Some of the side effects of the Thyroid being off mimic GvHD. I’ve been on some pretty rough stuff between the chemo and the anti rejection medicines. While going through all the treatments, I’ve fought to stay on the same dose of NP Thyroid. They’ve had me on Prednisone amongst other drugs. In the last year I’ve gained weight and have not been able to take it off. The Oncologist thinks that my metabolism has been permanently changed. My Endocrinologist talked me into adding 13 mg of Tirosint in August with hopes that the weight would come off. Hasn’t happened! I’ve had some issues that are mimicking menopause, but had a hysterectomy 16 years ago and been on .025 Estradiol ever since. My labs are all coming back good, so now I’m wondering if this has to do with the change in the NP, or truly my metabolism changes.

        Let me know how I can get the lot numbers and if I can help in anyway.

        Best,

        Jan

        Reply
        • Janie Bowthorpe

          It could very well be because NP went greatly downhill from what it used to be, report many patients.

          Also, it’s practically impossible to be optimal one only 105 mg, even when NP used to be a better product. And now, NP appears to be greatly compromised, report patients. This is why so many are now switching to synthetic T4 with synthetic T3 to avoid the NDT mess, and making sure they get optimal. One gal switched to Armour, but added in T3, got both her frees optimal, and seems well. Read what optimal really is here: https://stopthethyroidmadness.com/optimal

          Reply
          • Jan P.

            Read your post on being optimal, thank you! I’ve been fine on the 105mg for years. I have always needed only small doses of any medications that I’ve taken, so I’m not concerned with not getting enough. When I do get bumped up the feeling of being overdosed is to overwhelming and I come down pretty quick. After going through all the cancer and GvHD, I would rather feel just ok, than overdosed. For me at this point it’s a matter of quality of life! If I’m home not being able to control my feelings or heart rate, and feeling ultimately like I’m hitting a wall at periods of time in the day; than I’m not living the life that was graciously extended due to the bone marrow transplant. I except I will never get into the box everyone wants me in.

            My question to you is: do you want the lot numbers from my NP, and if so, how do I get it.

            Thank you,

            Jan

          • Janie Bowthorpe

            Hi there. It sounds like you need to be doing what’s on this page: https://stopthethyroidmadness.com/adrenal-info

            Oh and we’ve got a many lot numbers doing. So no need. 🙂

  11. Ann

    Hi Janie,
    I am wondering if you have ever seen antibodies go down on Synthetic t4/t3 combo? The reason I ask is I recently went in to my doctor to switch after this whole issue with NP. My antibodies had recently started going down on NP after being steady for over a year. My doctor said she hated to switch at this point because she has never seen antibodies come down while on synthetic t4/t3 combo. I have been at this for over 3 years and just really confused as to where to turn at this point. I don’t want to give up the gains I’ve made but don’t want to be putting poison in my body either. Thanks so much for your help.

    Reply
  12. Lynn

    So, the synthetic t3/t4 doesn’t seem to be doing me any favors. I have stopped and started a couple of times now and once I get to day 2 I get a headache on the top of my head, fatigue, feel warm with no fever and very sad. Also feels like someone is sitting on my chest. Not sure what to do now. Maybe stop taking everything? I haven’t felt good since Naturethroid failed me in June 2019. Had a couple of good weeks – once starting with the decent Np and once starting the t3/t4.

    Reply
  13. Susan

    I’ve decided to go back to Synthroid and Cytomel until Acella works their problems out. Is there a reference I can share with my doc re: raw materials coming from China? Also, Can you please point me to information on converting my NDT dose?
    My pharmacist says 95 mg. NDT=158 mcg. Synthroid but I’d like to know how much Cytomel. Thank you!

    Reply
    • Janie Bowthorpe

      Your pharmacist’s comment is why we’ve learned to take what pharmacists say with a grain of salt, if even a grain. What you start on, or close to, is what you were on with NP. One grain equals 38 mcg T4 and 9 mcg T3, so by that, you can figure out an equivalency with both T4 and T3. After a few weeks, do the frees. This is your goal: https://stopthethyroidmadness.com/optimal

      Reply
  14. Susan Hannum

    I’ve decided to go back to Synthroid and Cytomel until Acella works their problems out. Is there a reference I can share with my doc re: raw materials coming from China? Also, Can you please point me to information on converting my NDT dose?
    My pharmacist says 95 mg. NDT=158 mcg. Synthroid but I’d like to know how much Cytomel. Thank you!

    Reply
  15. Mara

    I take a digestive aid made by Standard Process called Zypan. It contains hcl, bovine pancreas Cytosol extract, pepsin, ammonium chloride, bovine spleen and ovine spleen. I just opened a new bottle and this bottle has the SAME cat pee smell as my most recent NP thyroid refill!! I have no idea if this has anything to do with what is going on with NP, but Zypan has NEVER smelled like this!

    Reply
  16. Angie F.

    Another reminder to sign the petition to Acella’s CEO, Harold Deas, at MoveOn.org. Here’s the link: https://petitions.moveon.org/sign/np-thyroid-by-acella/?source=search

    Reply
  17. Ryan

    I just realized that after I talked to Steve at Acella around a month ago, I never received the fetch bottle they were supposed to send me in order to test my failing pills. I guess that line was another shot of bs to help sooth the burn they’ve dealt us. I guess Steve can cozy up with the notion that if we all jump ship, he’s out of a job.

    Reply
  18. joseph

    does lithium carb. and seroquel affect thyroid conversion?

    Reply
  19. Janet

    I’ve only seen this conversion chart in one place online…it may be something Acella provided to healthcare professionals. I started with a lower comparable dose of Synthroid just because it’s better to undershoot at first if you have any cardiac issues. It doesn’t give T3 so you have to use the 4:1 ratio to approximate the dose for that. But it might be useful as a guideline.

    https://lh5.googleusercontent.com/vvYKgmaFdNY5IbwBDnHTnVHoplRpb_s2Kesu6lfbTxZlO_cfigtUzrrG1bpjRjMeBghrCfaezJiT7c5172D930nVmV3NcvZArJYRuZ4LlFoXxi00LzDjse6e1RNd6l_6_y_YVIBj

    Reply
  20. Janet

    Update on switch to synthetic T4/T3:

    I’ve been on the name brand Synthroid and generic T3 for two weeks now. My doctor felt it was too early to see any changes, but I politely disagreed so he let me do the testing. Free T4 was 1.02 which is pretty normal for me. Free T3 was 4.4 (usually about 5). But TSH had climbed 3 points which I had suspected because my thyroid gland was swelling and my resting heart rate had dropped to the 40s along with a lower body temperature. So my body is definitely feeling the change. NDT is about a 4:1 ratio of T4 to T3, but I started with a 15:1 ratio to show my doctor the T3 really is necessary (75 mcg T4 and 5 mcg T3 in a split dose). I’m going to increase T3 now to get it closer to the NDT ratio and we’ll retest in a couple of weeks. Because of a muscle disease I have which is affected by low thyroid, an endocrinologist I saw several years ago said to keep TSH in the .5 range, so that’s my goal for now.

    I’m so thankful I have a doctor who is willing to work with me and responds immediately to messages on the portal. He will make any adjustments needed to make me feel better even if it kind of goes against traditional protocols. I wish the same for all of you!

    Reply
  21. Sue R

    Has anyone tried the brand Levo-T for synthetic T4? Synthroid is way too expensive in my area to consider. I would add generic (Sigma Pharm) brand Cytomel with this for the T3.

    Reply
  22. Ryan

    Just updating, almost completed my month dosage. I have bad days and really bad days. The non-stinky pills eventually became stinky, so obviously there’s some sort of decay. Guess I’m gonna have to jump back to naturthroid or jump ship to something else. For those taking Cytomel and Synthroid simultaneously, is this a cheaper option than our NDT choices?

    Reply
  23. Tania Cully

    I meant my nightmare with Erfra, and Armour…I’m on Acella now. Sorry brain fog already lol

    Reply
  24. Tania Cully

    I am in the UK and have been taking NP Thyroid for five years . buying it from a great source in the USA. I changed from Acella when that went down hill, after hypo symptoms returned . I am on 3 grains of NP split into two does and was OPTIMAL. I have had great labs, near the top T3…mid range T4….sometime low to mid range. And suppressed TSH. But i have felt great on NP. Never had to think about my Thyroid for years. Roll on last week when I got the new batch . Bearing in mind I have taken this for years. I tasted it …SO, so SWEET !!! Tablet looks a bit bigger . But the taste was SO different. Alarm bells went off. I opened another new bottle out of the three I bought, they tasted the same out of that bottle too. I have today googled a change in taste in NP Thyroid and was GUTTED to read this, as I went down this road of misery with Armour and Acella . Oh God…Not NP too. !!! I may just go the synthetic route if my GP will prescribe it, but I cannot imagine life without T3 now . Can I buy synthetic T3 from somewhere ?? I think this new batch will send me down. I will report back . But the taste change must be for a reason.

    Reply
    • fliss

      tania i am in UK too and had same nightmare as you with Erfa did so well for 5 years never felt so good then that changed and switched to NP now cant use that, I got really ill on last batch couldn’t take….. I am going to be trying synthetics for first time later this week . I managed to get GP to prescribe t3 by doing a hand written prescription for a brand that is £100 for 100 , 20mcg tablets as opposed top £250 for 28 tablets that came up on his screen! that’s how they stop `GP’s prescribing t3 they make it too expensive. the brand is THYBON HENNINGS ….you can get it from chemist 4 u its on the thyroid uk website under pharmacies. I am going to take it with a ~T4 brand called `ACTIVA and see if hopefully I will be ok….theres not much left to try and im really hypo now. good luck and let me know if you manage to get GP to prescribe and how it goes . if he won’t you may be able to get him to do a p[rivate prescription for them, they are definitely the cheapest t3 ive found anywhere..but others here may know more ..im just looking at UK market.. I will post on here once started and done bloods.
      fliss

      Reply
      • Tania

        Hi Fliss
        Thank you so much for getting back in touch with me . A life line. i have been on the New batch of NP for two weeks now. I know this may sound daft, but the first thing for me to notice that goes, before I start the journey of hell to hypo is my hair goes flat and chewy!!! It hasn’t started to come out as of yet, but I have not had this for years . I have coasted along happily for years on the NP and obviously when everything is working well, you stop looking for any problems. Labs good, and felt great . Your information has been so helpful. If you would be happy to share emails, or have a chat about this I would certainly appreciate your help . Of course, I’m happy to chat on here . I will have to start this journey ….again….from scratch . So sorry you have too, but what you have written is a great help and starting point . xxxxx

        Reply
  25. Vernon Miller

    Started taking the new formulation of NP Thyroid on October 20, by October 28 hypo symptoms were returning. Now Nov 4, symptoms are worse. Blood work scheduled for tomorrow. No lot number or expiration date available.

    Reply
    • Tania Cully

      Good luck with the bloods!! I will be very interested in results.

      Reply
      • Vernon

        Blood test came back unchanged. So it is something else in the tablet making me sick. My doctor gave me a 2 week supply of the old formulation. Almost immediately I started feeling better. Checking into an online pharmacy that tests every batch they sell. My local pharmacy told me they had no way of telling me what batch number my last prescription came from. Done with them.

        Reply
  26. Dina L Ciccone

    I need to get on something, anything stat… they ran out of WP, now NP is literally harming me. How to do I switch to synthetic without losing weeks or months of my life? I need advice on what to do so when I call my Dr. she will know what to order for me.

    Reply
    • Janie Bowthorpe

      One grain of NDT is 38 mcg T4 and 9 mcg T3. So whatever you were on can be figured out accordingly. For example, 2 grains if 76 mcg T4 and 18 mcg T3, etc. Then after a few weeks of whatever you were on, redo labs and tweak as needed until optimal.

      Reply
  27. Janet H.

    Hello! My NP experience is a sad and disappointing one as well. I was optimal for about the past 6 months finally after starting NP a year ago. I was finally getting out and enjoying life. I got the smelly batch about a month ago but wonder if NP was taking a nose dive before that because my numbers were already dropping on my bloodwork a few weeks prior to noticing a difference in the pills. When I tasted them the first thing I did was check this site (thank you STTM!!) and braced myself for a return in symptoms. With my numbers already declining, sure enough within about 3 days I became a weepy mess for about 4-5 days. I was able to switch to Armour and within a day was feeling better, however I’m back to living in the couch again when I’m not working. I hope to be able to get back to feeling energetic again. I’m so disappointed in NP thyroid for taking chances with others health and singlehandedly forcing me back into a hole that took so long for me to dig my way out of 🙁

    Reply
    • Janie Bowthorpe

      You said it very well about NP and Acella, Janet.

      Reply
      • Janet H.

        Thank you Janie! Something else I forgot to mention is that I had 2 strange symptoms over the last couple months that I never guessed came from NP thyroid but have disappeared since switching. One was dizziness when I bent over to pick something up. My head would spin for a second when I stood back up. The other was waking up in the morning feeling like dust had gotten into my lungs, I felt like I had to cough it out and assumed it was because of the weather or dirty air filters. One week off of NP and realizing both symptoms are gone. Could be coincidence but seems very odd!

        Reply
        • Rita W

          Janet, I’m experiencing the same dizziness. I don’t know what is causing it. Now I’ll add NP Thyroid to the list of possibilities.

          Thanks for sharing this.

          Reply
  28. Janet

    Since several have asked, this is the conversion chart I’m using, not the ones that you would use going from synthetic to natural.

    https://www.rxlist.com/thyrolar-drug.htm

    I started taking Thyrolar back when Armour changed their formulation. It was synthetic T4/T3 and worked great for me for many years until it was discontinued. On this chart, Thyrolar 1 would be the same as 1 grain of NatureThroid or NP Thyroid, so you can calculate the equivalent for your dose. Maybe showing that to your doctors would help.

    Reply
    • Sue R

      Jamie, could you provide some insight on converting from NP Thyroid to Synthetic T4 & T3? When NP Thyroid was good, I was taking a total of 75mcg (60 plus 15). Amount of T4 in 75 mcg is 47.5, and amount of T3 in 75 mcg is 11.25 So the closest to that in Synthetic would be a 50 mcg Synthroid and 1/2 of 25 mcg tablet (12.5 mcg) of Cytomel. Would that be a good starting point?

      Reply
      • Janie Bowthorpe

        I’m on my phone and can’t get to my calculator, but if you took into account that one grain has 38 mg T4 and 9 mcg T3, them compared that to what you were on…you may be close enough to the approximate amount of T4 and T3. It will take doing the frees every few weeks and getting optimal.

        Reply
        • Lynn

          Is there any benefit for using a compounded t3/t4 vs synthroid and Cytomel? I am doing the compounded route and am having a challenge with a headache on the top of my head, hair pulled sensation and feet tingling once they raised me to the equivalent of 1.5 in NP from 1. I took a couple of days and those symptoms went away and yesterday tried again with lower dose and they were back again. I miss the old NDT’s.

          Reply
          • Janie Bowthorpe

            We’re with you about missing the old NDT.

            Do you know what the filler is they used?

          • Lynn

            They are using microcrystalline cellulose.

          • Di

            Janie, do you know if MCC or Avicel can cause these headaches? Since the NP fiasco, I was
            given Naturethroid and then Armour. They both produce awful headaches as Lynn describes, about
            an hour or so after ingesting. I cannot even drive, they are so bad.

          • Janie Bowthorpe

            That must be awful for you. Naturethroid is far from the great product it used to be, so I’m never surprised about problems. Armour can be better for some if T3 is added and one gets optimal. So not sure why they would do that to you. Why not move to T4 and T3 and get optimal?

        • Lynn

          Janie – what do you think about the filler in my synthetic compound t3/t4? it is microcrystalline cellulose.

          Reply
          • Janie Bowthorpe

            The cellulose can bind the thyroid hormones a bit. Just tell you compounder that for refills, you want acidophilus or olive oil, for example, rather than cellulose.

  29. Janet

    I’m doing really well on the brand name Synthroid and SigmaPharm generic Cytomel. What a relief…I was concerned that my holidays were going to be wrecked trying to adjust doses.

    Something that has been very unexpected is that I am sleeping so soundly. I can fall asleep easily even lying down to take a nap. It’s not fatigue…my energy level overall is much better. But it’s a deep, restful sleep that I haven’t had in many months. This really makes me wonder about some sort of neurotoxin in the new source material Acella is using. I think it’s deceptive that our labs may look normal and yet something is obviously interfering with thyroid utilization.

    Reply
    • Sue R

      Janet, when you switched to Synthroid and Sigma Pharm Cytomel, did you just match the amount of T3 and T4 that you were taking of NP for the conversion?

      Reply
      • Janet

        Sue, my prescription is for the equivalents on the conversion charts. However I took Thyrolar (liotrix) for many years and did fine, so I decided to start with that equivalent for the T4 and just a little lower on T3 and I’ll adjust that upward as needed according to tests. I’m getting a little bit of thyroid swelling today, so I’ll get my tests on Monday and make the first adjustment based on that. I feel fine, but don’t want to get a goiter. I’m just amazed at how much difference there is in the mental symptoms after switching…that’s why I think something was affecting my central nervous system.

        Reply
    • Angie F.

      I agree, Janet. One person mentioned ractopamine a feed additive to promote leanness in hogs/pigs for consumption as a possibility, and there were potential contamination issues with Sichuan Friendly. I haven’t made the switch to synthetics as yet and am unfortunately having to undergo a cardio workup Monday, but look forward to trying.

      Reply
      • Teresa Palmer

        Angie, forgive me if you described your cardiac symptoms before, but are you having PVC’s or SVT? I wish you the very best on Monday.

        Reply
        • Angie F.

          Hey Teresa…no problem. Until the cardio workup, all is pure speculation of course except for the definite PAC’s on the monitor at the hospital in the ER. The ER doc thought perhaps also paroxysmal A-Fib, but as yet that’s unconfirmed. Since you’ve missed what I’ve posted before, I’ll add that what brought me to the ER was palps, high HR and soaring BP (I’m a low BP person)..but EKG was normal (they consider PACs “normal”) and BP stabilized to high for me (135 over something) in the ER without meds. I began having problems simultaneously with an NP batch that I picked up in March from my local pharmacy. On/off from that time on..Palps and high HR got bad mid-summer, then improved briefly, then back again. My labs taken at my normal am time were a little lower than they had been…But ER labs one day after showed me with VERY high FT3, low-normal T4..like I’d been getting a quick T3 “dump” that didn’t stay with me. We shall see. Thank you for the best wishes. I’m doing okay..not great..but, with a nod to Jill Clayburgh, “semi-tough”. :):):).

          Reply
  30. Christine M Birkett

    Once again this website has saved me. I was certain I was going insane. NP was a lifesaver when Armour changed their formula. I have been struggling for months with return of symptoms including severe depression (depression was never an issue pre-thyroid), hair loss, sleeplessness, itching skin, forgetfulness & the worst FOG BRAIN ever. My job is complicated and very stressful this is so frustrating. Don’t they understand how much these changes impact our lives?

    Thank you for posting the updates. Thank you for your website. You guys saved my life.

    Reply
    • Terri

      I just took a dose from a new batch of armor….omg tastes like cat pee! I put a search in and came across this info. Thank you!!! The new tabs are grainy looking. Now to keep reading as to what to do…..

      Reply
      • Janie Bowthorpe

        Some pharmacies switch out different brands, such as switching Armour to NP. Are you sure you got Armour? Is it possible you got NP Thyroid? It’s happened to others and it’s irritating to only find out when you get home/

        Reply
        • Renee

          Oh boy! I can attest to that Janie. When WP originally went on back order, my pharmacy substituted naturethroid and didn’t inform me. I never looked at the bottle and never even noticed that I was taking a different pill. About a month later I was super sick. That’s when I happened to look at the bottle and learned that it wasn’t WP that I had been taking for the last month. I then had to call my doctor, get blood work done and switch to NP. It literally took me months to get back to almost where I was with the WP. Now I always verify before I leave the pharmacy. Lesson learned the hard way.

          Reply
        • Kay R

          Janie, people are complaining on ERFA FB about new ERFA …..change in color and smell. I won’t run out of old stock for a year, along with my T4 synthetic. They say they get porcine from Europe as well. I was looking to change to NP when I saw all of the posts. Thanks for being an advocate for all of us.

          Reply
      • Terri

        Im’ sorry. No, I had NP and had to have my doc change it to Armor. There went 3 months of NP down the drain and not even sure if Armor is working these days. I just know i’ve been feeling like hell. Visual changes, exhaustion, the whole nine yards on the previous 3 months of NP…if I hadn’t smelled and tasted the new one, I’ve been so foggy I wouldn’t have thought of it being the culprit…..

        Reply
  31. BarbN

    I just read the the NP Thyroid website FAQS several times…very tricky and deceitful wording.
    -One question asks about their quality control process and if anything changed with the update.
    They say they continue to use the same exacting quality control process and rigorous testing that they always have to ensure delivery of the appropriate amount of T4 and T3…
    Then they continue to say that every batch released to the market must meet the same quality and testing standards whether it was produced using ingredients from their former supplier or their current one – and that will never change.

    Whaaaaat?????? So it seems they are telling us not to worry because they test the final product whether it was made with either the old or new sourced API…are they kidding? What we the consumer are concerned about in addition to the T3 and T4 is any difference in what is in the new API compared with the old…of course it is different or it wouldn’t taste different…

    -Another FAQ is really tricky in that it asks if their new European supplier sources thyroid API from China or India?
    Then they answer saying no, the API is manufactured in Europe using porcine thyroid glands sourced entirely from European countries.
    What they imply is that they are no longer using any API from China or India but they are only telling us about their new API supplier…leaving out that they are still using the API from the old supplier also…

    -Another FAQ asks why the new looking pills taste different…they then avoid answering the question by stating that the product shouldn’t be chewed…how could pills taste different without being made with different ingredients?????

    I think we need to request Acella add a few questions to their FAQS such as:
    1. Are you still using material sourced from your old supplier? Where was the old supplier material sourced from?
    2. What are the exacting standards for your API that you claim to meet? Measuring T3 and T4 only? What else are you measuring to ensure the API hasn’t been contaminated, changed, cut with another material, etc?
    3. Is the manufacturer testing the batches that are produced? Do you or a 3rd party test the final product to ensure the product meets specifications or do you rely solely on the manufacturer who has an inherent conflict of interest if specs aren’t met?
    4. Was any of the product being sold now manufactured by Izeen Pharma or another manufacturer using the API material sourced from Sichuan Friendly?

    I’m sure I could come up with a lot more that might actually give us some actual information…I’m going to see if I can send these questions to Acella and get any substantive response…I’ll post again if I get any response

    Also found Acella in a lawsuit with Izeen Pharma (the same manufacturer that made the lots that Westminster voluntarily recalled) on docketbird.com
    Federal Court Cases Civil Cases Northern District of Georgia 2018 2018-cv-00000 through 2018-cv-00499 Acella Pharmaceuticals, LLC v. Izeen Pharma, Inc.

    This just seems to get worse as more information is uncovered…

    Reply
    • Elle

      Great digg, BarbN!

      Reply
    • Angie F.

      Interesting…I’ll look at today. One of the things that concerns me, and not just with Acella, is the Sichuan cross-contamination possibility from Class II solvents AND other medications…So..it’s pointedly NOT ENOUGH for Acella to test for T4 and T3 levels which we already know (potency variation also a possibility given Sichuan’s lack of GMP), and which are substantiated by labs, are inconsistent. Encourage everybody to do their FDA Medwatch reporting AND also to report to Consumer Product Safety Commission…Report an unsafe product form can be found at this link. Let’s make some noise…https://www.saferproducts.gov/CPSRMSPublic/Incidents/ReportIncident.aspx

      Reply
  32. Kellie

    My dr put me on NP thyroid back in July. My levels were normal..but DR was helping me with symptoms of hypo. I had a complete hysterectomy 4 years ago and was hoping for some relief. I was advised not to take HRT..this was my only hope. My symptoms since then…(had no idea it was the meds, until I researched)
    Bloated..headaches…burning pain in my stomach…3 times my lip swelled..(since Sept & October refill) itchy scalp…exhaustion…feel like my entire body is tingling.
    I actually tested this out. I stopped for two days and started back yesterday. Woke up this morning with dark circles under my eyes and hives on my face.
    Went to urgent care and currently waiting for meds…prednisone, zantac, benadryl and levothyroxine. (will wait till I speak with my endo before I take another thyroid med) If anyone out there has switched to Levo…please let me know.

    Reply
  33. Janet

    An update on my quest for a replacement…

    I’m doing really well with the name brand Synthroid…no reaction to the fillers. I’m not using the full conversion dose that I’ve seen on charts, but rather the dose I used when I was on Thyrolar which was 75 mcg. I want to use the least amount needed to maintain optimal levels and will adjust as we check free T4.

    The T3 was proving to be more of a challenge. I started with the Mayne brand generic Cytomel. I had a mild reaction to the first dose and took it two more times, each time getting a worse reaction including throat swelling. I talked to the pharmacy and they said their other option was SigmaPharm’s brand so they ordered that for me. My insurance declined payment and told the pharmacist they needed me to confirm I’d had a reaction. I spent 1/2 hour on the phone going over it and then they said my doctor had to call instead. This was on a Friday afternoon. I called back and said I was taping the conversation, and if I experienced heart failure over the weekend because they refused to approve the switch then I made sure my family knew they had denied coverage. They changed their tune and overrode the declined submission.

    So I’ve now tried the SigmaPharm T3 and seem to be fine with it. It’s great to have readily available options that hopefully won’t change over time. I have more energy and clearer thinking than I’ve had in months. It makes me wonder if even before the litter box tablets there were changes in the formulation altering the effectiveness.

    Reply
    • Janie Bowthorpe

      Glad you found out about the magic of having direct T3 in your treatment!

      Reply
    • Angie F.

      Thanks so much for posting…Gives me hope for T4/T3 therapy for myself and perhaps a brand, besides Cytomel, with which to start. Kudos on the insurance company a$$-kicking…so tired of their crap on top of all the other crap patients have to deal with. It’s as if they want us to pay huge premiums, co-pays, and deductibles…for, wait for it, n-o-t-h-i-n-g. Great work if you can get it.

      Reply
      • Janet

        Angie, the name brand Synthroid works great sublingually. The Mayne T3 tasted very metallic, didn’t split well and was not good sublingually. The SigmaPharm brand is completely different…tastes fine and splits cleanly even though it’s not scored.

        Reply
        • Angie F.

          Janet…How did you convert? As closely as possible to mcgs of T4/T3 you were getting in porcine or other method? Thanks.

          Reply
          • Janet

            Angie, I am using Thyrolar’s old chart (it’s no longer manufactured). It was an ideal ratio for me back when I took it. I think the conversion charts for natural vs synthetic are maybe a little too high on the synthetic side. The assumption is that natural is more bioavailable, but that was not true for me. Thyrolar 1 on the chart would be equivalent to 1 grain NDT, etc.

            https://www.rxlist.com/thyrolar-drug.htm

    • Karen

      Hi Janet had you tried synthroid before. I had used it many years ago but started having reaction to it. Not doing well on tirosint sol. I need to take Something my Dr won’t prescribe t3. Just asking if you you had bad reaction to it previous. Thanks

      Reply
  34. Patricia

    My email to Acella today:
    To Whom It May Concern …
    I spoke with Steve twice back in August 2019 about taking a huge turn for the worse after a refill I picked up on 7/22/19. Within 3 days of taking this refill I knew there was something terribly wrong with NP Thyroid. I have been thru this before with Armour, ERFA, WP Thyroid & now NP. When I spoke to Steve, he stated someone would call me back about replacing my refills but no calls were ever received??? I saw my doctor on Thursday 10/24/19 & my blood levels are thru the roof compared to 6 months ago. Current dosage was 75mg x 5 & 90mg x 2 for an average of approx. 80mg a day. Although I have not been optimal, I was getting close & felt really good for several months, up to the end of July. Then I started on the new refill & all my symptoms came back with a vengeance.

    My doctor decided to renew my NP (what other choice do we have now other than synthetic?) but increase the dosage to 90mg for now. I picked up my refill at Sam’s Club in Glendora, CA today & what I got was 12 tan pills (like the old, good pills) & 18 grey pills that smell like cat pee. I asked the pharmacist to see the original bottle & the Lot # & Exp Date are M331G19-1 & 12/2020 according to the actual NP bottle but my script label says the exp date is 02/21? I showed him the difference in pills & asked if they combined lots into one bottle? Unfortunately, he is only 1 day a week at this pharmacy & I will have to go back on Monday to talk with the head pharmacist. According to your Prescribing info “NP Thyroid tablets are light tan, round tablets, debossed on one side with “AP” and a 3-digit code on the other side.” NP Thyroid tablets are NOT GREY. In the pictures below, you can clearly see the 12 on the bottom are “Light Tan” & the 18 on top are grey. 1st pic taken indoors, 2nd pic taken outside in the sunlight.

    In prior “Prescribing Information” documents you listed Maltodextrin as one of the Inactive ingredients but the current revision 0719-01 on your website has this ingredient removed? Sounds like a formula change to me, but what do I know? In your product update you state NP should be swallow not chewed. However under “Pharmacokinetics – Animal studies have shown that T4 is only partially absorbed from the gastrointestinal tract. The degree of absorption is dependent on the vehicle used for its administration and by the character of the intestinal contents, the intestinal flora, including plasma protein, and soluble dietary factors, all of which bind thyroid and thereby make it unavailable for diffusion. Only 41 percent is absorbed when given in a gelatin capsule as opposed to a 74 percent absorption when given with an albumin carrier. Depending on other factors, absorption has varied from 48 to 79 percent of the administered dose. Fasting increases absorption. Malabsorption syndromes, as well as dietary factors, (children’s soybean formula, concomitant use of anionic exchange resins such as cholestyramine) cause excessive fecal loss. T3 is almost totally absorbed, 95 percent in 4 hours.” It is common known fact that 90% of patients with Hypothyroidism and/or Hashimotos also have gut issues, therefor it is most practical for us to take NDT’s sublingually (not necessarily chewed, I don’t chew, I sublingual under my tongue).

    Over 1100 comments regarding the ineffectiveness of NP Thyroid today. https://stopthethyroidmadness.com/2019/08/22/uh-oh-np-thyroid/#respond
    I realize this email will fall on deaf ears as it has with all the other NDT manufacturers over the years but I feel better, sort of …

    Reply
    • Starr D.

      I know what you mean about having been through this with different
      thyroid manufacturers over the years–for me, it’s been with both synthetic
      and natural thyroid. Complaining after getting ill when they change it,
      but getting nowhere. Just wanted to say that my last batches of NP
      were also gotten from Sam’s Club (Long Beach, CA), and they also
      seemed “mixed” to me. Some pills seemed good & helpful, and some
      were horrible and made me sicker soon after taking them. No weird
      odor on mine, though–just a lot of the pills were fatter than they’d
      been, previously. The 60 mg (one grain) ones seemed more mixed with
      good & bad pills than the 30 mg. ones. The 30 mg. ones just seemed
      BAD and really got to me after I’d taken a few weeks worth.

      Reply
  35. housemaid

    I agree with those who think there is a whole lot of Sichuan Friendly porcine powder floating around and for some reason only Westminster recalled their pills. Were they more honest or did they just get caught? They have not yet returned to making NDT. I think RLC Labs, Acella, & others used their Sichuan Friendly powder, either knowingly or because it was not labeled. I think that the “European” source Acella claims they are sourcing from is an eastern European middleman. I think Acella knows exactly what is wrong but is not going to admit it and lose money.

    Most likely any pharmacy that compounds NDT is going to be using the same Sichuan Friendly powder until it is all sold. I was sorry to hear that someone called about Thyroid-S and was told the porcine powder used in it is likely from China. I had hoped it was from Thailand.

    Here is something interesting that I found: https://www.alibaba.com/trade/search?fsb=y&IndexArea=product_en&CatId=&SearchText=porcine+thyroid+powder Porcine thyroid powder for sale, all from China, but not Sichuan Friendly unless they changed their name.

    Reply
    • Angie F.

      Yes…I posted about this a few days ago and I’m glad we’re all starting to pay attention. In all of the shared negative experience (and I’ve had issues with ALL meds (Naturethroid, Armour, and especially NP since spring of this year, perhaps even prior), this certainly sticks out like a sore thumb.

      In my post below, I posted a link to the FDA Alert on Sichuan which stops short of any mandatory action to companies potentially utilizing the powder (Sept 2018). Westminster issued their VOLUNTARY recall prior to the FDA Alert..so it looks to me as if Westminster may have had adverse reporting, connected the dots and did their due diligence to protect patients. However, any company potentially using Sichuan’s API would have gotten a March 2018 “Import Alert”, including Westminster. And also would have received the FDA Alert.

      The following is a link to the FDA letter on June 22, 2018 to Sichuan which discusses several major points that they felt had failed to have been addressed from an audit in October of 2017; note Sichuan was placed on “Import Alert” in March of 2018. (1) Solvent contamination..(2) Failure to adequately document cleaning and maintenance of equipment (3) Failure to demonstrate or correct cross-contamination of solvents a/o API carryover from solvents or other drugs (4)Failure to document or demonstrate stability of API [e.g.,potency] (5) Failure to demonstrate, document or prove “shelf life” of API (6) Failure to demonstrate that computer systems could not be tampered with to “change results” on testing. The FDA recommended that Sichuan obtain a consultant to figure all this out, which seems to signal that the FDA officials involved sensed some level of incompetency and ineptitude. Yet, the FDA did not issue any mandatory recall direction nor put the kebash on import until and unless Sichuan got their problems worked out.

      Link to FDA Letter to Sichuan..https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/sichuan-friendly-pharmaceutical-co-ltd-546990-06222018

      LInk to FDA Alert https://www.fda.gov/drugs/drug-safety-and-availability/fda-alerts-drug-makers-recall-porcine-thyroid-api-sichuan-friendly-pharmaceutical-co-limited-china

      Just let me say again that I appear to have retained from all this a potentially PERMANENT cardiac arrhythmia issue. I am in the midst of figuring all that out as well as what thyroid replacement meds I will be able to take in future. Unbelievable.

      Reply
  36. Mara Miles

    I just picked up my refill for NP Thyroid. I had printed out the list of the “bad” batches and the expiration dates. The pharmacist was open to talking with me. We looked at my “good” pills and then looked at the last batch I had received which had the strong cat pee order. She smelled them and was quite surprised. She looked through her NP supplies and found a bottle that was not on the list (although it did have one of the expiration dates on it). It did not smell badly. I took it home and my husband and I tasted it. The cat pee essence was definitely there but very low odor. I have decided to go onto compounded synthetic T3/T4. My husband is still deciding if he wants to try the new NP batch. We see his doctor in December and he can ask then about doing synthetic T4/T3 if he decides to try that.

    Reply
    • Michele Nelson

      Where Can I find the list of bad batches? I’ve been scrolling through and can’t seem to locate it????

      Reply
  37. Christa

    What is the best way to find where to order Thiroyd or Thyroid-S? The few websites I found Thiroyd was sold out. My husband was on this about 5 years ago (I have a bottle still, will it be bad if it is that old? Could I still use?) and did okay. He is currently on WP and is doing horrible now. Has been doing great but is now starting to crash – he says it feels like he is taking sugar pills. He reacted horribly on NP previously, but prior to WP going out of production he did wonderful on it. I am at a loss, I don’t want the midnight trips to the ER again….

    Reply
  38. Scott

    I heard Janie on the Primal Blueprint pod on Monday 21 Oct, and finally got around to looking at the STTM site today. After reading this article, WOW JUST WOW. I started to feel off in June, and have been progressively getting worse and worse since. I have gone over the symptoms and had labs with my prescribing doctor, and have had other tests/blood work done to rule out other problems, but nothing else has come back as positive.

    Me = diagnosed with non Hashimoto’s hypothyroid in 12/2016. I am on my 2nd doctor for this, and am currently taking T3 20 mcg AM, Acella NDT 1-1/2 gr AM, T3 15 mcg PM, and Acella NDT 1 gr PM.

    I can’t remember exactly when the smell changed, but it was definitely over the summer. I noticed the pills looked different too; although I never thought to take pics or measure them. I get a weird feeling in my stomach. I have so many symptoms since summer it would take forever to list, but the Cliffs Notes version is that I feel as if I have the worst hypo symptoms you could ever imagine combined with the feeling of being poisoned + a hangover like feel 24/7 even though I don’t drink alcohol. Plus I get up multiple times throughout the night and can sleep for half the day and still feel terrible.

    The strange thing though is that my lab values for FT3, FT4, RT3, etc… really haven’t changed that much since the summer; it’s just the symptoms that got worse and worse over time.

    My next appointment is on Tuesday; I will print out and bring this article and see if he will agree to take me off of NDT for the time being and either use another med or compounding pharmacy for the NDT in addition to the generic cytomel I am already taking.

    I will try to read all of the comments on here. It is really hard to focus if anyone has any thoughts or has gone through similar I would be grateful for your feedback.

    Reply
  39. Teresa

    Greetings all,
    I think that I may have some insight into what may be happening. My husband and I had been receiving compounded NDT since 2009 and doing very well. In January of 2018, our bottles of caps sported a helpful label stating that although the product looked different, it was the same medication. I questioned the pharmacist, who had no other info for me. These caps had powder that was markedly grainier and dark, with large black flecks in it. The smell and taste (taken sublingually) was what I imagine it might be like to chew on cow or pig innards. The product though was much much stronger, and we had to reduce our dosages slightly. Then late in 2018 our compounder told us that he could no longer obtain the raw thyroid powder needed to fill our prescriptions. It turns out that the manufacturer of the raw powder was Sichuan Friendly. We switched to NP and have been doing well on it. And then I opened my new bottle. Friends, it appears to be the SAME stuff that the Chinese firm was shipping out! Same smell, same taste. The odd thing is that this med is much much weaker. I think that two things might be occurring at once. They’ve sourced some of the Chinese powder (perhaps without realizing) but they have also added a very strong filler that has rendered the med completely ineffective for those who cannot assimilate fillers. Sichuan had been using faulty formulas to calculate their dosages, and I think that they had an adulterated product on their hands. How much of this re-labeled product has gone out into the marketplace we can’t know. I am quite ill with palpitations. If any know a mail order pharmacy that compounds NDT and ships to VA, please let me know. Contacted Woodland Hills and was told they can’t ship to us in VA. I wish you all wellness and a resolution to this crisis, but beyond that, let’s fight for our health.

    Reply
    • Janie Bowthorpe

      That is incredibly interesting, Teresa.

      Reply
    • BarbN

      Teresa,
      All that you have put together is really interesting…I have suspected for some time now that there is still some if not a really large amount of the Sichuan Friendly porcine powder still circulating and being used in pills that are being manufactured now and/or pills that were manufactured and never recalled from other companies. While scouring the internet and FDA website I found a Warning Letter by pure luck and chance that was sent to a contract manufacturer, Izeen Pharma. This warning letter to Izeen Pharma lists several lot numbers that were recalled by Westminster and gives detailed information of the violations that were found. Very eye opening to say the least. Not sure if Izeen Pharma is still a contract manufacturer for other NDT brands. The letter is on the FDA website: Izeen Pharma Inc, MARCS-CMS 565311 — MAY 16, 2019

      Janie,
      Do you know if Acella actually manufactures the NP Thyroid? Most of the Acella labels say “Manufactured for: Acella Pharmaceuticals LLC” which makes it seem that Acella may not manufacture the pills but contracts this out and the Acella label is applied after they are bottled. This might explain why it is so difficult and time consuming (and probably expensive due to manpower and time required) for Acella to actually find and correct issues that the contractors are having with the raw material, quality control, manufacturing consistency, etc. And more importantly, why they really don’t want to acknowledge any problems and provide any answers.

      It is really concerning that it is so difficult to find out what violations are related to the NDT we are taking and ultimately what is being done about it if anything. Was Westminster the only one that issued a Recall for the the bad lots…how many more contractors/manufacturers received the Sichuan Friendly API and knowingly or unknowingly used it in the NDT being dispensed today? From their website it doesn’t seem that Westminster supplies NDT anymore.
      The timeline is really concerning considering a large majority of us probably refill every month or 3 months…
      -October 23 to 27, 2017 FDA inspected Sichuan Friendly facility (Sichuan Friendly responded to violations on Nov 17, 2017)
      -March 22, 2018 FDA placed Sichuan Friendly on Import Alert
      -June 22, 2018 Warning Letter 320-18-59 sent to Sichuan Friendly
      -Aug 8, 2018 Westminster Issues Voluntary Nationwide Recall of Levothyroxine and Liothyronine (Thyroid Tablets, USP) Due to Risk of Adulteration
      It took over 9 months after the Sichuan Friendly facility was inspected for the Recall to be issued by Westminster…(and this was a voluntary recall which I guess means many others did not volunteer to recall their NDTs?)
      It took about 5 months for Sichuan Friendly to be put on import alert after the inspection so I guess the unacceptable API continued to be supplied to the NDT manufacturers during those months????
      I saw my doctor yesterday and made the decision to start taking synthetic T3 and synthetic T4 this morning and hope to be able to optimize using them. I am frightened by the consistent lack of transparency about what is really happening to these once wonderful NDTs and so upset that these companies continue to discount our concerns, symptoms, and ultimately our lives.
      Sorry for the super long comment…I am still in shock about how absolutely unbelievable all this is.

      Reply
      • Janie Bowthorpe

        Your sentence towards the end starting with “I am frightened…” hit it right on the nail. It’s been nothing but secrecy, lack of transparency, gaslighting, discounting, minimizing…

        Reply
      • Lynn

        I thought I read that the recall was due to bad practices. Was it actually proven to be bad?

        Reply
    • Sharon

      Teresa, I spoke to Murray Ave Apothecary here in Pittsburgh PA on Friday. I am switching to compounded Desiccated thyroid. My original plan was to go with compounded synthetics instead. The pharmacist told me they have Dessicated thyroid powder and they send it out to a lab for additional testing. I’m going to try and hope for the best. You could call them and see if they ship to Va. I trust the owner Susan Merenstein she is also a pharmacist. They are also a PCCA pharmacy. Since NP’s debacle I’ve been very ill due to not refilling my script after reading about it here. I’ve been using thyro gold 300mg for 4 weeks now and my levels really plummeted. My doctor said I’m not getting anything. I have just increased it to 450 mg as per the owner I need something for now till I get my compounded meds. Hope this helps,

      Reply
      • Teresa

        Sharon,
        Thanks so much for the info on Murray Ave. I’ll contact them on Monday. I hope that you’re able to bring your levels to optimal as quickly as is safe. BarbN, thanks for the most helpful timeline and the info about the letter to Izeen Pharma. I feel as though we’re putting together a clearer picture of events. Someone mentioned this much earlier in the thread, but the African Pig Fever has decimated perhaps 5 million pigs in China, who are the world’s largest consumers of pork. US is a distant second. This occurrence will likely have long term effects on the availability of raw porcine powder worldwide.
        Regarding the T3/T4 synthetic combination, does anyone have any knowledge of the lack of T1/T2 with respect to T1’s effect on the electrical charge of the brain? I found one source that indicated that the absence of T1 could lead to ALS. Alarming—but I haven’t been able to verify. If anyone has found info on this, would love to see. Janie, many many thanks.

        Reply
  40. Rita

    I wanted to update my older comment. I went back to Naturethroid after tasting the new NP. At 1.5 grains my T3 was low, so I was raised to 2 grains. Now I feel horrible 2 months in. My pulse and heart rate are higher and I feel nervous, stimulated like I am on coffee, and can’t sleep well. I had 2 panic attacks where I had afib for several hours. I have never had this issue before. I haven’t got my labs back, but I dropped my dose to 1 grain right now and will ask to be changed.

    Should I try Armour or just start on synthetics? i am so tired of this. I haven’t been optimal for almost 2 years thanks to Nature-throid. But this hyper feeling is the worst. I actually felt better hypo, other than my hair falling out…

    Reply
    • Angela Frye

      Rita, I am so with you on your comments. I started feeling “hyper” on an NP dose that was the same as I have been taking for about 5 years now, in July. Have had palps, high BPs, an ER visit and problems ever since. I went back to Armour for a few days…still problems…trying some old Naturethroid right now…still feeling overmedicated. Something is just not right. I’m in the midst of investigating problems from my end…cardiac workup..autoimmune flare evaluation, RBC magnesium and potassium levels, and if all that proves okay, iron and cortisol checks. I did have a VERY high end FT3 about 2 hours post med (never happened before), but a lowish FT3 the day before and both times LN FT4…Almost as if I’m getting nothing but a quick hit of T3 after meds and then nothing. I’ve put up two petitions at MoveOn to both RLC and Acella, so I’m not sitting on my hands about involving myself in a solution, but resolving this problem will take the entire dessicated thyroid pt. community. Please let us know if you get to any reasonable findings or solutions.

      Reply
      • Starr D.

        Angela, have you tried mentioning something about your petition on
        Facebook pages like Hypothyroid Mom and Thyroid Sexy? Those
        are two of the better ones, I think (of course, Janie’s STTM is GREAT),
        but I didn’t know if you’d like to message them about maybe posting about
        your latest petition (the one with 69 signatures)….or? You did a really
        good job with this petition, and I’d like to see it get even more names on it.

        Reply
        • Angela Frye

          Starr…please feel free to share and circulate the link to BOTH petitions anywhere you frequent. And that goes for everybody. I can’t be everywhere and resolving this nightmare requires community effort.

          Reply
    • Jenny T

      Rita, have you checked your cortisol levels? Your symptoms sound like cortisol levels that are off. I’m on hydrocortisone for low cortisol, and when I tried raising NDT from 1.5 grains to 2 grains, I got similar symptoms. So now I’ve had my aldosterone tested, and may need to take Florinef as well so I can handle raising my NDT. Janie says if you can’t tolerate a raise to 2 grains or above, you need to check your cortisol and/or iron levels.

      Reply
      • Rita

        Jenny T, you have a great point.

        So I went in and talked about my labs with my doctor, they are perfect on 2 grains. High T3, midrange T4, 24 hrs since I took the last dose. Never looked better. All my hypo symptoms are gone. Hair staying in my head, no more weight gain or tiredness, regular periods and a little lighter, etc.

        I talked to my doctor about my concerns of recent raising blood pressure, fast pulse, nervousness, not sleeping as well, panic attacks, etc and she thinks I am having bad anxieties, and I think she might be right. After reading all of the negative things on Naturethroid here and on other sites, it made me convinced that I was having issues from Naturethroid. Every little pain/feeling I immediately assumed was caused by my 0.5 grain raise in Naturethroid. I was 100% convinced I was hyper. I have struggled with anxieties at times over my life, and we had some stressful events the last month, so it might make sense that I am just stressing myself out. Anxiety and hyper symptoms are very similar. But my lab numbers say I am not anywhere near hyper…

        I will research the cortisol. That would make sense. She also suggested taking a low dose beta blocker for a while until I get calmed down. I hate taking prescription meds (I only take Naturethroid and I am 50) , but I broke down and took one last night and felt so much better today. Lower pulse, healthy blood pressure, not stressed, more relaxed. I even slept better. Basically like my old self on Naturethroid 2 years ago.

        She was willing to change me to any thyroid I want, but pointed out my numbers are excellent and I have a history of anxiety. I sometimes felt this way when I was hypo… Stupid anxiety disorder.

        So it was either change thyroid (which can have a huge adjustment time) or take a beta blocker for a while and work on reducing stress. Both methods aren’t perfect, but since my numbers are great and I have had a history of being nervous, this way makes sense for me.

        My iron is fine, just need to check my cortisol. But I already feel 95% better one day on a low dose beta blocker.

        I do know that people are more likely to post negative reviews on drugs rather than positive. My doctor has many patients on Naturethroid that she claims are doing great. My mom has been on T4 only for decades and has perfect numbers and feels good. So there is hope for all of us. Just need to find out if Naturethroid is giving me problems or I am just a nervous wreck making myself sick. 😂

        Reply
        • Janie Bowthorpe

          Naturethroid has been giving a lot of people problems since last year. We have definitely not seen anyone who is really doing great. They may feel better, but they certainly aren’t optimal. and they appear to have problems that they don’t realize are because of the naturethroid. And it’s destined to backfire eventually.

          Reply
          • Rita

            I know, I am worried about taking Naturethroid. But my labs are excellent. My doctor will change me to synthetic T4, test me, then add T3 as needed. But I hate to change when I already have perfect labs. And I have felt anxious before even when hypo, I have an anxiety disorder. I am just beyond frustrated right now… She already has switched me to NP then back to Naturethroid when NP went south, so she thinks it is all in my head.

          • Janie Bowthorpe

            That sounds nuts for your doctor to just switch you to just T4, then test. it sounds like your doctor is refusing to believe that T4 only is the wrong way to go. We already know that forcing the body to live for conversion alone is ridiculous. You need to be switched to both T4 and T3 then test. Fight for yourself.

    • Rita

      Update: So I stopped taking the beta blocker after 3 days, I started getting depressed! But I have been taking the AdrenaVive supplement my doctor gave me and I am feeling better. Apparently my adrenals are wack. No wonder my anxiety was sky high. So feeling more calm, sleeping better, and still on 2 grains Naturethroid. Pulse my normal high pulse (80-90) and blood pressure good. I am also exercising, meditating, and trying to reduce my stress. I have energy and am starting to feel like my old healthy self!

      Reply
      • Janie Bowthorpe

        Glad you are feeling better! Though AdrenaVive won’t work for low cortisol (years of experiences on that since it’s only adaptogens), it can work for someone with stress and rising cortisol with its ashwagandha and other adaptogens.

        P.S. Naturethroid just isn’t what it used to be and has caused a lot of problems. Just an FYI. See if you can get optimal on it: https://stopthethyroidmadness.com/optimal No one has been able to, but it may be worth trying as long as you don’t get worse by raising.

        Reply
  41. Angela Frye

    Also…has anybody thought to contact Westminster, the company that DID issue the voluntary recall after the Sichuan Pharma issue? They might be able to shed some light on the subject. I read at least one post on this blog thread that had previously gotten their meds compounded from Women’s Int’l who told them they had no raw product available and didn’t know when they would. My question is, that if that is the case, who does? Forest/Allergan? And what is being put into the meds we’re currently being given? Synthetics? My labs look almost as if I’m only getting T3…and it’s dumping and then clearing out of my system rapidly…with high Free T3 one day post med and lowish Free T3 prior on the same dose as I’ve been taking for years now which has my levels usually pretty good (recent problems experienced aside).

    Reply
  42. Sharon

    Can anyone please help. I’m going to try compounded synthetics t3 and t4. I started Thyro gold 4 weeks ago got labs back today and my levels have plummeted. I feel blooming awful! I would love to keep increasing this but just can’t afford to be feeling this bad. I’ve only ever tried
    over 25 yrs ago when first diagnosed and had life
    threatening reaction. So, is there any specific brand of synthetics that the compounding pharmacy needs to use? I really don’t know much about them. Also, beginning to realize I’ve probably never been optimal in all these years. Thanks to Janie I’m really pushing for this now. No wonder my hair never grew back and I’ve never been able to lose all the weight I’ve gained no matter how hard I’ve tried. I really would appreciate any feedback on this.

    Reply
    • Eneida

      Hi Sharon, I was taking NP thyroid and feeling pretty bad, gaining weight, brain fog etc. I decided to do compounded T4 and T3 as Janie suggested and I feel so much better, you can’t imagine. Have only been taking it for a couple of weeks but it’s already made a huge difference, I take T4 38mcg and T3 9mcg 2 times per day. Hope this helps, Eneida

      Reply
      • Sharon

        Thanks Eneida! Do you take synthetics now? Do you mind me asking what fillers they use? And, what pharmacy? I’m going to see doctor today who is willing to work with me on whatever I would like to try.

        Reply
  43. Angela Frye

    Reminder to everybody to sign the petition regarding NP Thyroid by Acella…Also, for some reason, MoveOn has removed the “deliver to” name which is, for everybody’s edification, “Harold Deas -CEO”…Let’s keep up the pressure. Please circulate and share widely. I’ve just come from the hairdresser’s where I was told that I had some hairloss also in addition to my hyPER issues and problems. Great..just great. Petition link. STTM, I’d like to renew my request to share the petition on your social media pages as a thread. Both the RLC and the NP petitions. https://petitions.moveon.org/sign/np-thyroid-by-acella/?source=search

    Reply
  44. edison carter

    Had been getting my NP Thyroid, which was working better than any other NDT formula I’ve had for years! (120’s) from Express Scripts through the mail, for about a year+. After I got the bottle in August 2019, I thought maybe it had spoiled in transit due to summer heat here in TX, so I had them resend me another bottle. Same deal. So I went to Costco to check it out there. It was only slightly less bad. I decided to switch back to Armour, but after a few weeks I can already tell it is not as good at the same dose of previously excellent NP Thyroid. Argg.

    I called Acella and spoke to customer service there; they did not mention anything different than what is posted on the Acella website regarding the formulation.

    Reply
  45. De

    I have been taking 90mg of NP Thyroid for over a year but the past month or so (with receipt of my three month refill), I’ve been dealing with extreme fatigue again. Now I know why! Has anyone switched to another natural desiccated thyroid and had good results? I’m not going to keep taking NP if it has clearly been reformulated and no longer working for me.

    Reply
    • Janie Bowthorpe

      De, that’s also a paltry amount that was destined to backfire like this, even if the changed NP would do it, too. 🙁

      Reply
      • De

        Janie,

        So you’re saying that the dosage is too low? I’ve been fighting with my endo to keep me on the desiccated thyroid (I don’t want to go to synthetic) and although I’ve asked her to increase my dosage, she won’t due to my blood work (which I think she is relying too heavily on and not interpreting correctly).

        Reply
        • Di

          Same problem with Naturethroid/Armour. I am thinking of stopping the medicine
          altogether for a few days, and suffering, to get a lower TSH reading–so the dr.
          will prescribe more! Desperate.

          Reply
          • De

            Di,

            I can empathize. I did the same thing a year ago. Pathetic we have to alter our meds so we can ‘play the game’ with our doctors. I actually ordered some OTC desiccated (bovine) thyroid to supplement with my NP Thyroid. Started with 25mg/day on Monday (taken with my NP) and will see how I feel in a couple weeks. Fingers crossed.

  46. Janet

    I just got an unopened replacement bottle sent directly from Acella to my pharmacy because of reactions to my most recent prescription. It was just as bad and I actually got an anaphylactic reaction this time. I’m definitely filing a report with the FDA. I talked to Steve at Acella and he said he only takes down the adverse event reporting and doesn’t know anything about current status of testing, supplier, etc.

    I’m starting to go into panic mode now. I’ve never done well on any synthetic except Thyrolar and it’s not in stock. I don’t tolerate Armour, NatureThroid or Erfa. I was fine with NP until I got a prescription filled in September. If I don’t get at least 1 grain a day (my script is for 2) I will get heart failure quickly. Labs were fine before, now low free T4 (TSH is always low because of pituitary damage so we don’t use that – doctor didn’t order T3 this time). All iron parameters look good.

    Can anyone suggest a dye-free synthetic they have tolerated? I’m thinking about asking for Synthroid 50 mcg tablets but they are crazy expensive since my insurance won’t cover.

    Since everyone seems to agree on the cat urine smell and taste, I’m wondering if there new supplier is using ammonia in the extraction process that is not being removed in the final product.

    Reply
    • Karen

      Janet you could try tirosint sol
      It is a liquid version of levothyroxine
      But if you’re insurance doesn’t cover it very expensive.

      Reply
      • Terry

        With the Tirosint their website has coupons to lower the price. Also, Good RX gets the price lower as well.

        Reply
    • Starr D.

      Janet, just wanted to say if you do try Tirosint as Karen
      suggested (it came it soft gelcaps when I took it), you might want
      to take a little less than your normally do, and take it in two servings
      at least (two gelcaps or more to make your daily dose) and spread
      it out during the day–morning, afternoon—because Tirosint can
      hit people more strongly because of the liquidy gelcap form–it’s
      supposedly absorbed more quickly. When I started it, it helped
      with some symptoms the other drugs weren’t helping with, but I
      had to get off it after a few years because it seemed to give me
      some new symptoms I couldn’t deal with. Everyone is different,
      so read some current reviews on it, if you can (I’ve been off it for
      about four years) Web MD or wherever might have some more
      current opinions on it. Lowest dose it came in was 13 mcg, then 25
      and 50, etc. Split it up into at least two doses–that’s your best shot,
      if you’re sensitive….and start a bit lower than your normal final dose.
      Or take the white 50 mcg. of whatever brand to make your dose–I’ve
      gone that route in the past, too (not sure how much it helped, though.)

      Reply
      • Janie Bowthorpe

        But try to have T3 with it.

        Reply
        • Janet

          Thanks! My insurance wouldn’t cover it, so we’re starting with Synthroid (name brand) and generic Cytomel (Paddock brand). If that doesn’t seem to be working I’ll look into that.

          Reply
          • Janet

            Found out the generic Cytomel they ordered was made by Mayne. I had a mild reaction the first day I tried it and a much more severe reaction the second day. So they said they’d get in a bottle from SigmaPharm and see if I tolerate that one better.

            The good news is that I’m doing really well on the name brand Synthroid. I feel so much better already, both physically and mentally. Lots more energy and clear thinking after several weeks of depression and fatigue on the new “litter box” NP Thyroid batch.

          • Janie Bowthorpe

            Yes some people do better on T4 only than others. But a body is never meant to be forced to live on conversion alone from T4 to T3. There’s too many issues which can negatively affect that conversion. Far better to have some direct T3 in your treatment and get optimal.

  47. Angela Frye

    I’ve put up a petition to the CEO of Acella asking him to respond to our questions and concerns. Please sign, share, and otherwise circulate. https://petitions.moveon.org/sign/np-thyroid-by-acella

    Reply
    • Allyson Williams

      Thanks Angela. Signed!

      Reply
    • Starr D.

      Just signed it, and left a big, long comment–couldn’t help myself, sorry!
      I’ve been through too many of these thyroid drug changes over the years,
      and they have messed up my health so badly. I really hope you can
      get something going with this. Good luck.

      Reply
    • Jennifer M

      I signed the petition! I took this new formulation for 6 days and my hypo symptoms came back. I also started getting bad anxiety attacks by day 6. I called my doctor and luckily she had a couple months worth of samples that she sent me. Working on figuring out a plan after these pills are gone.

      Reply
    • Angela Frye

      Thanks to all for signing. Please don’t just sign. Share and circulate and encourage as many signatures as possible. Starr, I read your long comment. Please don’t apologize. Heartbreaking experience for you..And for all of us.

      Reply
  48. Angela Frye

    Below comment was posted to this week’s blog also, so 2nd time posting to ensure visibility. If not allowed, please feel free to delete… I did occasionally, if I remember correctly, have palps (as did another person responding to your “new WP” blog) on NP…Did not have on the good N-T..So at that point, don’t think it was adrenals. However, with the roller coaster ride that dessicated has been since the Naturethroid debacle, and an inordinate amount of personal stress, adrenals may well be a factor now.

    Unlike most of the people reporting feeling hyPO..I’ve felt hyPER.. First order of business is a cardio workup. One thing that I do want to bring to attention, though, is the FDA drugmaker alert on Sichuan Friendly API. Westminster voluntarily recalled their product, but according to the FDA alert, “However, FDA confirmed Sichuan Friendly’s thyroid API remains in the U.S. supply chain. This API and the drug products made from it, present a safety risk to patients. Sichuan Friendly API may be repackaged and/or relabeled before it is further distributed, and not all of the repackaged/relabeled API identifies Sichuan Friendly as the original API manufacturer. Therefore, manufacturers and compounders who make levothyroxine and liothyronine drug products should contact their API supplier to verify the actual manufacturer of the thyroid API they received before using it. Sichuan Friendly’s products may be labeled as “Thyroid Powder” or “Thyroid Powder USP.”

    Here’s the link to the entire alert…https://www.fda.gov/drugs/drug-safety-and-availability/fda-alerts-drug-makers-recall-porcine-thyroid-api-sichuan-friendly-pharmaceutical-co-limited-china

    If I read the alert correctly…the FDA alerted and advised manufacturers but did not force their hand on a recall, which Westminster voluntarily did. So..we don’t know where or in what meds this particular API ended up. Or what the response of the individual manufacturers was, IF they utilized API from this source, again with the exception of Westminster, who appeared to care enough about their patients to issue a recall. And, interestingly enough have not, at least as far as I know, put product back out on the market leading me to wonder whether there is even another API source.

    Trying to open the actual Import Alert, also link to follow, but the link is not responsiv Important note, only actually published 10/17, over a year after the initial alert to manufacturers. https://www.accessdata.fda.gov/cms_ia/importalert_189.html

    Reply
  49. Sharon

    I have been reading about the outbreak of African swine fever killing millions of pigs in China and other countries. There is a story on The Compounder pharmacists website about this too and how it might affect the difficulty in obtaining the raw porcine. I’m also wondering about the effect this has had on obtaining the raw porcine material for NDT. Also, the ash content some are talking about. These pigs are being burned. So makes me think maybe it’s contaminated some of the raw porcine. Just a thought!

    Reply
  50. Maria

    This post is about the burning esophagus. I too had to switch from Naturethroid after the changes last year and went to Armour instead of NP. Doing well on 2.5 grains until this week I picked up a refill and within one day my esophagus and chest are burning. The pills look the same as my last Armour and still name brand with the Armour logo but slightly more shiny and hard.I’m seeing these postings about NP causing a burn and I’m wondering if anyone else is also having it on Armour and do they get their raw ingredients from the sameness source and if so I’m really worried.

    Reply
    • Anna

      I also have that burning, and really fear I have long-term damage, and frankly quite scared. I TOOK the pills all September and a few days in Oct, they switched me back to Nature-throid, and basically, IT is no better! Just did labs, but still need to have T3 and 4 done, I think something is clearly wrong with the pills now

      Reply
      • Laura

        I am also have burning but it’s in my stomach. This just started after I got my refill of NP!

        Reply
        • Karen

          Laura I have been off np since September 8 and still have burning and pain in my stomach throat and intestines.Their was an interesting story on the news this morning. They found a new enterovirus in the feces of pigs in China they said effects the DNA they don’t know how it attaches itself to the host and will be studying to find out more. I think all thyroid powder is contaminated right now read the post above about her reaction to armour this is not good.

          Reply
  51. Ashen

    I have the labs to prove that NP is no longer working, but it is still working better than Naturthroid did. In July 2019, I got labs that said my Free T3 was 2.9 pg/mL, and my free T4 was 1.05 pg/mL. I was feeling good and my hair was thickening up from the Naturthroid disaster. Then I got a new bottle of NP thyroid in August 2019. I definitely noticed the terrible smell and taste. My hair started thinning a bit again in September, but I hadn’t put things together yet. My new labs from October 2019 show a huge difference. My Free T3 dropped down to 2.3 and my T4 dropped to 0.92. This sucks! I don’t know if I should try Westminster, Armour, or up my dose. The bad taste makes me want to switch.

    Reply
    • Russ

      Sadly, My recent tests are about the same.
      TSH was .12. Now 2.48
      FT3 was 3.3. Now 3.1
      FT4 stayed the same at .8
      TPO Antibodies rose from 802 to 837. They were 1,239 when I was diagnosed. Spoke with my Dr. about going on LDN to try and bring them down.
      And gained 6lbs in 2 months.
      I started noticing hypo symptoms about a week after my new prescription but didn’t realize so many were having a problem until I read it here.
      My Dr. started me on a bio-identical T4/T3 med today. I hope this nagging muscle ache in the middle of my back isn’t already a side effect.

      Reply
      • Janie Bowthorpe

        You’ll do very well on the two synthetics, but it’s very important to get optimal, which you weren’t and aren’t. See this: https://stopthethyroidmadness.com/optimal

        Reply
        • Russ

          No, defititely not optimal. And sadly, even though my new Doctor practices integrative medicine, and is willing to prescribe other meds, she is showing signs of using the TSH as the gold standard.
          If anybody near Orange County or LA County has found a good Doctor, please give their name and location.

          Reply
          • Beth

            Just taking thyroid hormone replacement might not be enough. I was diagnosed with Hashimoto’s 20 years ago and have always been on Armour and recently NP. It was not until I was diagnosed with celiac disease (anemia was my only symptom) and treated with a GF diet that my thyroid nodules and enlargement resolved. You can have more than one autoimmune disorder. Unless you treat them all, just taking thyroid replacement helps, but it is not enough.

            By the way, Type 1 diabetes (which you can develop at any age and celiac disease) are the two autoimmune disorders most commonly related to celiac disease (they share the same gene types).

            Easy to get tested for celiac disease. Simple blood test. I urge everyone to get tested before going gluten free because all celiac testing required you to be on a full gluten diet. Celiacs can be asymptomatic and it is systemic affecting fertility, the brain, joints, bones, etc.

          • Janie Bowthorpe

            Correct, just taking the right thyroid hormones is one of many strategies those with Hashi’s and other autoimmune issues need to do, including avoiding gluten.

            There’s also now a good patient-to-patient Hashi’s book called Hashimoto’s: Taming the Beast with a great deal of good information, including a chapter on 96 short testimonies of what patients are doing to get antibodies down for Hashi’s, for one. There is also info on what autoimmune diseases can combine. https://stopthethyroidmadness.com/hashimotos-taming-the-beast

        • Ann

          When starting on synthetics like Synthroid my current script would be for 100mcg. and 25mcg. of cytomel. I understand to multi dose the cytomel but would I ask my doctor to split up the dose of the Synthroid? Thanks for your help.

          Reply
          • Janie Bowthorpe

            You can cut them or ask for smaller amount pills.

          • Janet

            Ann, I just got my new prescriptions for the synthetic T4 and T3. I checked with a lot of people first to see which seems to be the least allergenic brands, and they all agreed the 50 mcg Synthroid with no dye is the best. So I’m taking two a day plus two to three spread out doses of 5 mcg of a generic Cytomel which also does not have any dyes. I reacted just a little to the Cytomel but hopefully will tolerate it. I did fine with the Synthroid. I was concerned the name brand Synthroid wouldn’t be covered by my insurance, but my copay was only $2. Same for the generic Cytomel.

            I’m so fortunate to have a doctor and pharmacist who will work with me but it sure gets scary when you have to change something so essential to our health as thyroid replacement. I have standing orders for free T4 and T3 to make sure I’m getting proper doses. I did great with Thyrolar years ago so I’m hoping this will work.

          • Janie Bowthorpe

            If you react to the T3, time to do this page://stopthethyroidmadness.com/adrenal-info

  52. Wyline

    I switched to NP thyroid after I had the same terrible problems as everyone else this past summer when I refilled my NatureThroid. I didn’t realize how bad I was doing until I read about others similar symptoms and connected the dots. The switch to NP has been great for me – until I ran across this thread and immediately tried to get a new batch. The lot marked M that I was able to sniff reeked of cat pee and my pharmacist agreed with me. He is able to do compounding but told me that it will be very expensive. Fortunately he had various amounts and strengths of non-contaminated lots so I was able to combine and purchase enough to get me through early next year. I’m hoping things will be better after that but if you read the above article things look pretty grim to me.

    Reply
  53. Kelly

    I switched to a compounding pharmacy after the NP smelled and tasted awful (cat pee). I showed them the old NP and the new smelly ones and they could smell the difference. They get their thyroid powder from PCCA. They filled my order with a new batch of thyroid powder and it ALSO smelled like cat pee. They had an older thyroid jar of powder and compared them and they look and smell different. They let me take pictures of them with their chemical analysis. The old and new batch have a very different color and smell. The new batch has lactose and twice as much ash. I would like to send pictures to you but I don’t know how.

    Reply
    • Janie Bowthorpe

      Wait, the “compounded” thyroid powder smelled like cat pee??

      Reply
      • Karen

        Omg why is there ash in this at all. I also tried compounded this spring and reacted bad tried three fillers same reaction after hundreds of dollars said can’t do it. Was told they get thier stuff from pccp also.google the toxic effects of ash to humans this has alot of symptoms people are getting. You and this pharmacy need to report these findings to the FDA. I will never trust ndt again.never mind the smell just finding the ash and lactose is very alarming in itself. I am still so sick and said many times I feel like am being poisoned. Ash contains many heavy metals. What f nightmare.

        Reply
        • Catherine

          I am not following. What is Ash? Thanks.

          Reply
          • Ryan

            Soot, burnt/expressed carbon. It’s garbage filler. Could explain the gray discolorations in the pills.

      • Patricia

        I had a feeling this was an issue. No one knows whats in this new “Thyroid USP” which all the manufacturers are using now to make NDT’s. Obviously, it’s not just freeze dried pig glandular. https://www.pccarx.com/products/THYROID-USP-POWDER-(PORCINE)/30-1467/APIS-EXCIPIENTS

        Reply
    • Patricia

      Kelly, Can you post the pictures on the STTM Facebook page?

      Reply
      • Janie Bowthorpe

        Is Kelly allows me, I’m going to start a brand new blog post about this and will include the pictures.

        Reply
        • Karen

          Janie don’t you find this very concerning to know they found these ingredients in the porcine powder nothing should be in it but dried pig gland. Never mind twice the amount of ash or lactose. That pharmacist should know this and is mandated to report these findings. And to answer the person who said what is ash? Well it is either wood ash or coal ash. Both toxic to humans. I think this has been going on for a while. I would encourage her to report it instead of blogging because nothing is going get done just talking about it.

          Reply
  54. Patricia

    Janie …
    I Watched your videos from end of August. Just wondering how YOU are feeling? Have you run out of the old formula NP? Have you figured out what you are going to do now? I have tried Thyrovanz & Thyrogold but not having much luck. Tried going back to NP but it just makes me so sick. Getting blood tests in the AM & then seeing the doctor next week. I found an old supply of NP last night & took one & feel a tiny bit better today, only 6 pills though. Looks like we are in for a long rough road ahead. I hope you are doing well …

    PS: Someone posted on one of the Thyroid groups the strengths of T4 & T3 in Thyro-Gold – She said she called them & they gave her this info. The 300 mg pill = 100mcg T4 & 25mcg T3. So the 150mg would be half. Looks like the 300mg would be close to 150mg of NP or 2.5grs?

    Reply
  55. Lorie

    I’m thrilled to hear later batches are improving. I’ll have to talk with my pharmacist. Still dealing with the skin rash and a few other minor hypo symptoms. Had a crazy thought, it might be what the pigs are getting fed causing reactions in people. I’m allergic mainly to wheat, dairy, and nightshade. If the pigs eat a lot of potatoes that would explain my rash, increasing edema, headaches, etc. Seems like those with thyroid issues also have food issues with wheat, corn, nightshades, basically inflammatories coming through from the pigs to us. Any way to test how much solanine is ending up in the pills?

    Reply
  56. Jenny T

    Regarding Nutrameds desiccated thyroid, the tablets come in 130mg. Would these compare to the same amount of ThyroGold desiccated thyroid? I know the ThyroGold comes in 150mg and 300mg, and the 150mg size is equivalent to one grain of prescription desiccated thyroid (according to ThyroGold website). I know it is thought that the Nutrameds is weaker, but I don’t understand why, given that they are both dried thyroid gland, with some additives.

    Has anyone ever compared the efficacy of both of them, and what do you think?

    I am thinking about replacing my NP Thyroid due to the current issues. I have ordered Thyroid-S from Thailand, but it won’t be here for a month. I don’t want to renew my script for NP because I’m not even sure it works well, even though I have gotten “good” batches of it. So I’ll need a replacement while waiting for Thyroid-S to arrive. I already have a bottle of the Nutrameds desiccated thyroid. Thanks for any insight.

    Reply
    • Janie Bowthorpe

      Nutri-meds has always been a little weaker, so you end up needing more. No matter what you switch to just keep track of your free T3 and free T4 and get optimal.
      https://stopthethyroidmadness.com/optimal

      Reply
    • Elle

      Do I need a script to purchase Thyroid-S, and is it OK to name reliable purveyors of Thyroid-S? Where does everybody buy it?

      Reply
      • Janie Bowthorpe

        No script. And no, we can’t post purveyors of Thyroid-S, as there’s nothing more that the FDA wants but to close them down. It’s happened before.

        Reply
        • Elle

          Thanks, Janie. I thought that may be the case. What an awful conundrum for those of us without a thyroid. In my dreams I would love to see thousands of Thyroid Patients storm Capitol Hill and demand 1) steady supply of meds that keep us alive, and 2) an investigation into why this isn’t happening.

          Reply
  57. Karen

    Has anyone considered a possible mold contaminated extract? Because I remember back in July saying these pills have a mildue taste to them.Believe me I know about mold highly allergic to many strains.

    Reply
  58. Ryan

    Started a fresh batch of 60mg tablets this morning coupled with my current 15mg tablet from the original fill as a trade in for the stinky cat pee pills that weren’t working for me. After having swallowed my dose this morning, within 5 minutes, I was already feeling better. I was juiced with energy seemingly and got up to start my day at 7am instead of my alarm time at 8am. Absolutely not groggy, nor am I feeling lethargic, no headaches (thyroid migraine-type) and the only remaining effect is a slight numbness or tingle in my middle, ring and pinky finger on both hands. Feet are a little cold, but I’m not getting that flushing feeling like I have a fever or anything at all. Brain fog appears to be gone.

    I don’t want to cash my chips in on the new supply, but I definitely feel a little better, if not back to somewhat normalcy. If that changes, I’ll reply to this.

    Reply
    • Janie Bowthorpe

      Those are the mysteries we have to figure out i.e. did you get an old batch or have they made some changes secretly.

      Reply
      • Ryan

        Doesn’t appear to be an older batch, as there’s speckles or discoloration. The smell and taste are definitely gone and I certainly “feel better” but I wouldn’t claim it to be near as good as I was on the old stuff.

        Reply
    • Ryan

      As promised, I’m following up with the end of the day. Most of today was pretty good. Still some tingling in the finger tips and toes, but the hypo-headaches that I normally feel on the back of my head and neck, towards the top of my head are mostly gone. So some symptoms persist but are much less nagging than the dosage before, and I assume my body might be trying to get back into optimal range so this might be part of that. As I stated before, it was a trial getting off of naturethroid and getting onto NP, so some of these symptoms are very familiar. I’m hoping things improve from here, but I still feel a little run down toward the middle to end of the day. Hoping my experiences help, might be worth trying to swap out your stinky meds for ones that don’t stink. My pharmacist called me today and seemed heavily invested in my well-being and how I was doing today after starting the new fill. She agreed that there might be some soft hurdles to get back into adjustment, and it probably didn’t help that I was throwing additional dosages into my day with the stinky fill to try and balance myself out. Keeping my fingers crossed for myself and the rest of you. Hopefully there’s some light at the end of this crappy tunnel.

      Reply
      • Di

        This is hopeful; anyone else get a “good” refill? I am suffering on Naturethroid!

        Reply
        • Ryan

          As an update, symptoms come and go throughout the day. Mostly grogginess, tingling or numb/cold fingers and feet, occasional ocular headache, or back of neck which is a thyroid related migraine. I feel better than I was last week, still, but definitely not 100%. Someone posted that they were trying to get compounded thyroid powder but found out the new batch had more ash and lactose in it. Lactose inhibits thyroid absorption, which seems like a stupid move when you consider the purpose of these pills, unless they want their patients on higher doses to get their required thyroid hormone, thus generating a higher revenue due to the slight increase in price when adjusting dose. Seems farfetched, but pharma is so sketchy these days.

          Reply
          • Di

            I think you have hit the nail on the head! More fillers, weaker product means we spend more $ to get the same amount of pure medicine. Cheaper fillers or cheaper methods of production may account for the poor quality (and in my case, allergic reaction) to the new NP. It seems to be that way with everything! Clothes at the stores now are paper thin. Bacon (as just an example) used to be 16 oz., now 12 oz. packages for same price or higher. Everything is cheaper, smaller, thinner, and costs more. ‘nuf said.

  59. Angela Frye

    Yes, I do think there were problems with NP prior to July/August. I began to notice issues with a tachycardia incident while gardening toward the end of March and I’d noticed not so much fatigue in the latter part of the day, but a puny/blah apathetic feeling. I’d like to take the opportunity also to point out, that for one reason or another, certain fills seemed to coincide with higher RT3 on same or even lower dose. My single biggest complaint with NP, though, has been erratic BP and HR. I’d like to take the opportunity to repost here at the blog two comments that I have up at STTM’s Facebook page below.

    The hospital monitor Wed night during below described incident showed both PACs and PVCs in my case, with high BP (I’ve NEVER had…always lowish to low). I could feel these and doc/husband could see them on the monitor immediately after I felt. (PVCs reported by a former Naturethroid or WP user in response to a blog post about RLC problems, also with NP that resulted in a trip by him to the ER. Scary stuff. My posts below:

    STTM/Janie…I had a little trip to the emergency room Wednesday night on this med; with soaring BPs , erratic HR, and chest pain. . I’m waiting on some labs from Tuesday morning to report my findings more fully and I see my primary on Wednesday to discuss what happened and strategy going forward.
    Also..I’ve noticed that NP has stopped me and perhaps others from commenting on their Facebook page. In addition, many of the comments of concern have been hidden or outrightly removed. IMHO, that is not representative of a company that wants to do anything but damage control.

    So, I did finally get my labs back. I also had labs at the hospital (would have been about 2-3 hours after my PM dose). Tuesday labs; TSH .023L (.45-4.5), FT3 3.1 (2.0-4.4), FT4 .94 (.82-1.77):RT3 14.6 (9.2-24.1) so, look “normal”, if suboptimal w/ high RT3, but bear with me. Hospital labs; TSH.03L (no range given), FT3 4.7H! (2.3-3.9), FT4 .7 (.6-1.1). Would expect that different labs, esp at different times would be slightly different, but here is what it almost looks like to me…Like there is “uneven” distribution of hormone amongst pills a/o batches a/o added T3 which is very quickly in and out of the system. Irony is except for the soaring BPs and palps, I felt reasonably good. Sleep good except waking a little early. No to little edema, but easy weight gain/harder to keep off. . A comment on the STTM blog on this issue pointed to ractopamine as a potential feed additive contaminant. While I think it’s a little early to latch onto that as an explanation, my symptoms certainly seem (feeling hyper while LN) to fit. Not sure what I’m going to do. I have some Naturethroid fills from one of RLC’s mail-order pharmacies that I didn’t do well on either. I’ve gone back to some older Armour fills at a slightly lower dose until I see my PCP tomorrow and palps have lessened, but not disappeared. Think I’m going to ask for ‘scripts for both Armour and T4/T3 combo. I share everyone’s frustration, to say the least. Did well on Armour before change..Then BEST on ERFA before change..Then reasonably well on Naturethroid before change. Then just okay on NP, and now the current debacle. I DO plan to file FDA complaints, but wondering if a direct confrontation from the thyroid community with our leader:Janie, Mary, Elaine and a few hand-picked patients might be in order. Have included a ractopamine Wikipedia treatise link for those interested. https://en.wikipedia.org/wiki/Ractopamine

    Reply
    • Amy

      I was sick on NP from Feb & Apr of this year. I still have some of the pills and they reek. My RT3 went up on the NP as well and then came down again when I switched back to Nature-throid. Other than feeling really ill like I had a severe flu, tired, upset stomach I started getting debilitating headaches and severe leg edema. All of it went away when I stopped the NP – both times. I tried it 2x.

      Reply
    • Lori

      Angela, don’t you think your free T3 was probably high because you were at 2-3 hours post dose? T3 spikes in the blood and is hard to ‘measure’ unlike the more stable t4. Not saying you don’t need t3 but maybe you need to reduce it or spread it out more. Sorry about the hospital visit 🙁

      Reply
      • Angie F.

        Lori, I have considered that the hospital Free T3 measure was post evening med. However, post med measurements in the past have NEVER been that high (upper end of hospital range was 3.9, mine was 4.7). Somehow or another, I’m getting a T3 “dump” a/o something else in the NP that’s causing the BP and HR spikes and palps, and perhaps also contributing to the high RT3. Am wondering if the active ingredient has changed a/o is unevenly distributed. I have switched back to Armour on a lower dose (1 1/2 grain as opposed to 1 3/4-2 grain) and will talk to my doc about what to do in today’s appointment.

        Reply
  60. Erica

    I just started taking a new batch from express scripts. It doesn’t smell as bad as the previous batch from this summer(90 day supply). This batch taste a little sweet. I noticed the last batch smelling stronger, but just thought it was different pigs?! I’m also pregnant and have had to up my dose, so I didn’t realize people were having issues until I started this new batch. I was curious about the obvious change and searched the internet to see what was going on.

    Reply
  61. Jenny T

    I am wondering if the new formulations of NP Thyroid contain thyroid glands from dead pigs that died due to the African Swine Flu that is wiping out herds of pigs in Asia, and now in Australia too. I wouldn’t doubt if unscrupulous herd owners are selling body parts from sick animals.

    Reply
  62. Beth

    On NP Thyroid’s Facebook Page they posted on September 26th that they had in fact had a product update. They now get the active ingredient from Europe. https://npthyroid.com/product-updates/?fbclid=IwAR1XfdewX0Z3U7fuinKFMfomIQYiQgJXWxwyw6cgR9n-kyMTwMtnckgELQw

    Reply
    • Janie Bowthorpe

      Yes, a lot of people saw that. But that’s not admitting other clear changes. Specks, horrid smell, different taste, and a slow of bad symptoms reporting by many.

      Reply
  63. Amy

    I am glad to see this is coming out! I suffered on NP and was told it couldn’t be the NP. I experienced severe edema and it literally made me sick and caused debilitating headaches. Basically I was going hypo but the upset stomach was new. My labs supported how I was feeling. I was optimal before and after NP.

    I tried NP Acella 2x (2019 Feb & May) to confirm it was cause of my symptoms.

    Reply
    • Kris

      Did you report this? What are you taking now?

      Reply
      • Amy

        I reported to Acella 2x and they never responded. My doc was concerned especially after I took a break and tried a 2nd time with a different batch of NP but same result and it comes on quick. I stuck it out on the second round for 6 weeks and I got increasingly sick, the edema was getting scary.

        I had an old stash of Nature-throid which I restarted. I have since filled a new script for Nature-throid and I’m doing fine. My labs improved (Free’s & RT3). Notably I suffered a round of hair loss and the timing seems likely it was during my NP trial(s). It was frustrating as I kept telling folks even here that something is wrong with the NP so I’m glad to see this has come out so if someone has an issue they know it may be the NP.

        I still have some of the NP pills and they reek. I am not expecting odor less meds but these smell bad, something isn’t right with them.

        Reply
        • Janie Bowthorpe

          I think many would agree with you that something’s not right. The STTM Facebook page also did a post about burning in the esophagus and burning in the stomach after swallowing these pills for some.

          Reply
    • Kelia

      Janie, have you seen anyone produce labs to prove they’ve gotten optimal on something like Thyro-Gold? If faced with a choice of using the Thyro-Gold (or similar) or synthetic T3 & T4, which would be your first choice?

      Reply
  64. Christina K

    Yeah I was trying WP thyroid out for a while back in March 2019, and April too. That was reformulated too, quite a while ago. I didn’t do well with it at all, so I thought I’d try NP again. Well, first off, I tried out a compounded NDT which seemed okay, but my muscular pain was amplified on it, so I asked for NP again. The doctor gave me some free samples, and they were good. My new script of NP was filled last month, and it’s HORRID. It tastes like gasoline fumes, or bug spray. Disgusting. My hands are swollen, itchy, and I’m really tired too, and my throat hurts, my stomach gets upset more too. What a nightmare. I’ve been through old Armour, Erfa, NatureThroid, and now this. VERY upset.

    Reply
  65. Sharon Hagen

    I was frightened to refill my NPThyroid 120 mg. but could not get into see my doctor before I was going to run out. I did check with the pharmacist (at Costco) to make sure that what they had to give me was not from the batch numbers that have already been noted as bad and they said not. The pharmacist also checked and said he didn’t think the tablets had a strong smell so I…having no other option anyway….went ahead and ordered. I opened the sealed manufacturer’s bottle of 100 at the counter and there was no noticeable smell, smelled the same as my previous order filled last July. I still had a few pills from my previous order and when I compared the pills from the old and the new bottles there was no discernable difference in size, colour, or texture, no flecks in the new pills. I decided to keep the old pills and took the new pill that night. It dissolved under my tongue with no particular bad taste though it did very faintly have what others have described as an “insecticide” taste. It was so faint that it could have been my imagination, since I was afraid I would have the same experience as others with the new pills and might have been imagining it. I’ve been taking the new pills for a week now and haven’t noticed a difference in how I feel but I guess I’ll have new labs in 6 weeks and then I’ll know….or sooner if I start to have symptoms again. Is it possible that all our patient complaints have swayed Acella to fix what they broke ? Has anyone else made a recent purchase and had OK results ? I will post the batch number if someone can tell me where it’s found.

    Reply
    • Jeri

      Would you mind posting the batch number and exp date of your (hopefully) good new tablets?? I live in UK and get my prescription from the States. I am terrified of being sent the bad ones!!

      Reply
    • Ryan

      The lot number and expiration date will appear on the pharmacist fill-order bottle. If that’s what you have, it’ll start with an M and likely a 3xxxx-x number.

      Reply
    • Erin

      Hi Sharon, I just picked up a new 120 and 30 mg. They don’t have as strong of a smell and they still taste bad, though not quite as bad as they did before (not gag inducing anyway). Though I wonder if I have somehow become accustomed to the terrible taste? My pharmacist would’t help with batch numbers, so I’m unable to help with that. I’m not having hypo symptoms, though I am having the same strange head pain I had before I knew I had Hashimoto’s and before being treated with NDT. Now it’s back. It sounds strange, but my scalp hurts, almost like my hair hurts. I don’t know if anyone else has had this kind of pain. I’ve always thought it was connected to my thyroid or some kind of hormonal issue. I’m thinking of switching to Armour just to see if it helps with this pain.

      Reply
      • Valency

        I just picked up a new batch this weekend and the horrid smell is gone. I’m reallly hoping that they’ve fixed it.

        Reply
        • Janie Bowthorpe

          We’re hoping with you. Keep an eye on your symptoms, as my own husband was on the “normal”, non-changed tablets and his hypothyroidism came back on the same amount that he had soared on for a few years. That happened around mid-or-later summer.

          Reply
          • Julie

            Oh my gosh! I had the exact same experience as your husband over the summer! Ive been on NP Thyroid successfully for a year or more. Afternoon fatigue crept in and all get-er-done motivation was gone! Didn’t occur to me (because I was back in that fog) that it was my meds until end of summer because I have been stable for so long. Doctor switched me to tirosint with added T3 and I am back going again, however still trying to get optimal. I lost my whole summer and as a homeschooling mom that really SUCKS!

          • Janie Bowthorpe

            Yup, he went through the exact same thing…on the NP tablets that looked and smelled the same BEFORE the obvious changes with specks, etc. So something was going on then….

        • Ryan

          My pharmacist replaced my 60mg tabs today for a non-smelly version of them. The color blotches appear to still be there, but there’s no questionable smell anymore. I start them tomorrow, but to be fair, I’ve noticed a slight decrease in hypo symptoms since being on these stinky pills. Not sure if the body is getting used to it and processing them better or what. Pharmacist told me she literally had a phone call complaining of the same issues as I did right after I asked for mine to be swapped out.

          Reply
  66. fliss

    also my labs were optimal in April 2019 and in sept 2019 they were much lower below range. have muscular aches and pains and constipastion too so same as many on here. really scared about the future now desperate to find a solution.

    ps. Janie my first post seems to have disappeared have I down something wrong? wanted to add this to it. can I get it back or do I have to re write? sorry]

    Reply
    • Janie Bowthorpe

      I have only recently discovered that some comments were going into spam.

      Reply
      • Fliss

        Thanks Janie do you have any advice for me? I’m thinking maybe I should try and persuade gp to give me t3 and t4 but I know t3 costs loads here in uk and they don’t like to give it scared he may give me t4 alone which I reacted badly to years ago. Really want another ndt brand but confused as to which ones work still? Do you know of anyone here in the Uk ? Are you aware of the differences between problems in USA and Europe or are we all having same problem ?

        Reply
        • Janie Bowthorpe

          All I can say is that none of the prescription US NDTS are the consistently good products they used to be. That observation comes from many of us who have been on NDT a long time and know what they used to be, and also saw all the changes.

          Can you make the NDT’s today work? We’re still not sure. Armour, even with its changes, is the only one we wonder about, but we have yet to see someone get optimal on it. And being optimal is important.

          So your choices are taking T4 and T3 and getting optimal. Or ordering the Thai brand thyroid-s, or the over-the-counter brands like thyro gold or thyrovanz…or just be on T3. https://stopthethyroidmadness.com/optimal

          Reply
          • Fliss

            Thanks Janie I don’t think we have over the counter thyro good in the Uk. I will look into thyroid s is it easy to find ? And is it still working ? Or will try to get dr to try me on t4 and t3 . Do I just convert the t4 and t3 in 4.5 grains of np thyroid that I take into t4 and t3 and start stop np one day start t4/t3 next day ? Is taking t3 alone better than mixing t4 abc t3? I know it would cost more as t3 is very expensive here.

          • Janie Bowthorpe

            You send off for it. Check out natural thyroid solutions. com Or just T4 with T3 and getting optimal. One grain of NP is equal to 38 mcg T4 and 9 mcg T3 for conversion purposes. Taking just T3 is fine, too, but you’ll have nothing converting to T3 for you in the background.

          • fliss

            thanks for the info Janie. are we sure thyroid S works as ive looked to up and can afford it I think, its cheaper than thyro gold. which is best? do they Bothe work well? are they both similar in strength to Np thyroid? I was on 4.5 grains of NP so would i take 4.5 grains of thyroid s or is it stronger or weaker? it only seems to come in 60mg tabs so that’s 1 grain am I correct? so I would have to take 4 tabs a day = 4 grains then cut tablet in a half to get half a grain..is that possible?

          • Janie Bowthorpe

            Patients have been happy with either, honestly. Thyroid-S may be similar to prescription brands, but no matter what, we’ve learned to always retest our free T3 and free T4 after a few weeks of using a different med or supplement. Yes, 60 mg is one grain. A pill cutter can help, if needed.

          • Yesi

            I emailed Thyroid S , they stated that thier porcine was more than likely from China, is this worrisome?

          • fliss

            I cant keep taking the NP as feel really bad. is it safe to stay off thyroid medication when your thyroid is destroyed? if so how long for as I cant see. my dr for 3 weeks..will I be ok without for that long? i plan to ask if he can. try me on t4 and t3. I have found some old WP thyroid, they are out of date end; may 2019. no idea when i got them as date of prescription not on it, maybe 2017. they are brown and hard and dont smell like other NDTs..is this ok or do you think they are off? I could try them and see..but just bit worried . was WP ok in 2017 ? are they sublingual? ive never taken a non sublingual NDT…do you have to take away from food? can you crush and chew?

          • Janie Bowthorpe

            No, it will not be a good idea to be off that long. You can just switch to the wp as they last a long time. And you don’t have to do them sublingual. You can just swallow them too or chew them. Being able to do NDT sublingually was just a bonus (which Acella also ruined as reported by patients)

          • fliuss

            thanks Janie that’s helpful i will try old WP from tomorrow. they dont have the same smell as Erfa and Np and are dark brown is that how they should be? also is it worth, if they help, asking dr to try me on new WP…are people doing well on them or have they changed too? would you always recommend NDT over t4 and t3 together?

          • Janie Bowthorpe

            Not anymore would I recommend NDT over T4/T3. Understand that I’ve been around NDT for 17 years, and there are others who have been around NDT a long time, too. And we’ve all seen how they are not the consistently good and effective NDT’s they used to be at all.

            Now we still have some people saying they feel fine on them, yet they don’t produce labs to prove they are fine. Fine is only when your frees are optimal, which used to be easy to do: https://stopthethyroidmadness.com/optimal Otherwise, that fine will eventually backfire!! So just saying one is fine on them doesn’t give confidence in recommending them to others.

            I do like the OTC natural thyroid supplements like Thyrogold, et al. Can someone get optimal? Maybe. Even adding T3 to them would be fine.

          • fliss

            thanks for your insight Janie I really appreciate it. I have been optimal, my labs were always right on point on Erfa and then. again on NP until April 2019. I tried the WP thyroid and feel absolutely awful, nauseous.. aches and pains , felt better yesterday when I didn’t take anything. both those are making me ill. I think I need to try and get dr to try me on t4 and t3. I was on. 4.5 grains so how much t4 would I take and how much t3 if so? and do I just start on the equivalent to 4.5 grains or have to work up to it? I currently split does 3 times a day…does one do that with t4/t3 combo? I am also on HC 30mg split 3 times a day for past 6 years now under too much stress to come off.

          • Janie Bowthorpe

            Hi Fliss. One grain equals 38 mcg T4 and 9 mcg T3. Yes, might want to continue splitting, morning and early afternoon.

    • fliss

      so if im on 4.5 grains ndt and switch to synthetics I should take 170 mcg t4 and 40mcg t3 split across the day. would I dose 3 times a day as I do now or just 2 times a day? so twice a day would be 85mcg t4 and 20mcg t3 morning and afternoon? how many hours apart? or 3 times a day its more complicated maths ..not sure what size they both come in? do I go straight onto this dose of 170 and 40 or do I have to raise slowly?

      Reply
      • Janie Bowthorpe

        Twice a day works, like morning and early afternoon. We don’t have to be hung up on a certain amount of hours. I would personally just go to the equivalent of 4 grains and retest in 3-4 weeks.

        Reply
        • fliss

          thanks Janie have I got my maths right am I converting the correct way? 4 grains would mean 75mcg t4 twice a day and 18mcg t3 twice a day. I dont know what sizes they come in, not sure how I will get 18mcg of t3 as I think it comes in 20mcg so would it be ok to do 20 mcg t3 a day and 75mcg t4? if dr agrees to a trial I will do as suggested and post what happens. I went through all my bottles of NP thyroid and discovered some old ones from last year and 2017. I compared the colour , look and smell and the old ones are definitely more yellow in colour and no specks and smell better. I have about enough for a month so to keep me going until I see dr I am am starting on those today. I will post how I feel am hoping they will get me out of hypo state I am in, then hopefully try t4/t3.

          Reply
          • Janie Bowthorpe

            Hi. I’m not where I can do the math, but just multiply 38 x 4 to get the T4 amount, and 9 x 4 to get the T3 amount.

          • fliss

            thanks Janie. one question; im. having bloods done before I see dr as he wants a baseline. ive never been clear as to whether I take my NDT that morning . I have bloods at 1pm and take NDT at 8am. otherwise I worry that last dose day before ate 2pm there won’t be any t3 left in my system by 1pm the next day and will give false low? also if/when I switch to t4/t3 what does one do re bloods and last dose before ? I always have bloods around 1pm as that’s how surgery does it. also if dr won’t prescribe t4/t3 I will have to try thyroid s as seems no other options left> does that one work well , how strong is it compared to NP? do we know its sourced safely?

          • Janie Bowthorpe

            Take your thyroid meds as normal one day, then do labs the next morning before taking meds.

            You just try to switch to an amount of T4 and T3 that is somewhat equivalent to what you’ve been on with NDT. One grain of NDT is equal to 38 MCG of T4 and 9 mcgs of T3. Then in a few weeks, we redo the free T3, free T4 and rt3, and tweak as needed until optimal. https://stopthethyroidmadness.com/optimal

        • fliss

          thanks Janie so it doesn’t matter if there’s been 24 hours between having taken any meds and blood test? how can there be any t3 left in my system? is this the same advise if on synthetics?
          and is thyroid s a good substitute for NP if I cant get synthetics?

          Reply
          • Janie Bowthorpe

            This is about taking T3-containing meds twice a day like NDT or 3 times a day like T3. That way, it’s not 24 hours.

          • fliss

            I cant get my bloods done till the afternoon at my surgery that’s what was worrying me. what I will do is take either not or t4/43 afternoon dose later than normal day before bloods , something like 6pm.would that be ok with a 1pm blood test following day? if we are on t4/t3 is it best to take 3 times a day?

        • fliss

          hi Janie I managed to persuade my GP to prescribe t4 and t3 to try. im just waiting for them to be delivered tomorrow so will start Thursday. as you suggested even though I was on 4.5 grains NP when optimal I will start at equivalent to 4 grains which is about 150 msg t4 and 35mcg t3.
          just to be clear can you let me know im correct: I take my NDT ( old bottle of NP that I luckily found ) tomorrow as normal 3 x a day. ( I split it 2 grains 8am, 1.5 grains 12.30 and 1 grain 5pm. ) then the following day I can switch straight over to t4 and t3 and stop NDT?
          I want to continue to take t3 split 3 times a day as my body is used to getting the t3 in NDT at those times. I will keep to same time scale and do 15mcg t3 8am, then 10mcg 12.30 and 10mcg 5pm. ( the tablets are 20mcg so I will have to quarter them , hoping I can) but do I need to split t4 or can I just take it all 150mcg at 8am? also should I raise it all slightly to equivalent of 4.5 grains NDT ive been used to and if so when? I am booked in for bloods in 4 weeks then seeing GP to asses. I will post my results but i presume it may take more than 4 weeks to be optimal?
          do we have to take synthetics before food and if so how long before? is that t3 and t4 if so? do we avoid certain supplements if so what and how long between? im used to sublingual so never worried about food or supplements …
          I will post how I do on synthetics and really hope they work for me. is anyone else on here switching to t4 and t3 ? would be great to know how you are going if so?
          thanks for all your help and advice . fliss

          Reply
          • Janie Bowthorpe

            Hi. You really don’t need to take NDT more than twice a day, such as taking it morning and early-to mid afternoon, by the way. But since NP has now been so problematic, and you need to switch to T4 and T3, you could also try just twice a day as mentioned. The T4 will be converting to some T3 for you.

            Since it’s close to what you were taking, you might be able to recheck your labs in 2-3 weeks or so.

            No, many take with food, but they avoid iron, calcium (like milk products) and estrogen at the same time. Some even drink with coffee and cream and are fine. But it’s up to you. 🙂

          • flkss

            thanks for answering my questions Janie… but do I also need to split the t4 twice a day? or can I take the 150mcg of t4 just once a day at 8am?
            when would you suggest I try to raise to equivalent of 4.5 grains from 4 grains you suggest I start on? and why do you suggest that is it to see how I go by starting lower or are synthetics stronger?
            I presume its ok to just swop one day from NDT to synthetics the next day?
            and does it take longer than 4 weeks to see optimal blood results ? sorry to keep checking I just want to be sure im doing it right

          • fliss

            posting again as no reply: hi Janie but do I also need to split the t4 twice a day? or can I take the 150mcg of t4 just once a day at 8am?
            when would you suggest I try to raise to equivalent of 4.5 grains from 4 grains you suggest I start on or do I wait till bloods and then raise the extra equivalent to half a grain?
            why do you suggest that I start on equivalent to 4 grains when ive been on 4.5 grains for years is it to see how I go at first by starting lower or are synthetics stronger?
            I presume its ok to just swop one day from NDT to synthetics the next day?
            and does it take longer than 4 weeks to see optimal blood results ? sorry to keep checking I just want to be sure im doing it right

          • Janie Bowthorpe

            Moving to the T4/T3 equivalent of 4 grains is just to be safe, then test in a few weeks to see if you need to tweak and how much. Yes, a one day swap.

  67. fliss

    is anyone on here in the UK having this problem? I am in UK and starting having hypo symptoms and hair falling out nails cracking put on weight didn’t know why until I saw this. was doing great on ERFA for years until that changed swopped to NP did well until a few months ago. don’t know what to do as in uk I don’t think we can get compounded NDT? I am one of the lucky ones whose GP prescribes for me so I don’t pay as am unable to work and cant afford it. any suggestions on what to do as going to GP in a few weeks to ask him to prescribe something else and show him this? should I ask him to prescribe armour and crush it? if so do you crush in your teeth or before you put in mouth? or try t3 and t4. I take 4.5 grains NP have tried going up to 5 but temp is up at 37.3 and feel awful..should I lower until I get a replacement? thanks for any suggestions .

    Reply
    • Waveylines

      Feel for you Fliss. An on nhs script for np too. So far I seem to be still getting the original tablet & have felt fine. Ive been optimally dosed for 10years on ndt apart form the blips for Armour, Erfa changing knocking me sideways..lol.
      For once am at a loss of ehat to do….lol.

      Reply
      • fliss

        hi waveylines I am the same as you really happy on Erfa till change and then np till recently. its a nightmare working out what to do. what are you currently taking? im at a loss too as feel better when not taking any NDT now but know I will go downhill quickly . im going to see if ~GP will prescribe t4 and t3. what are you going to do? are you in the uk?

        Reply
        • fliss

          waveylines can you tell me the date you got the ones you’re doing fine on and the batch number and exp date please? so I can compare to mine
          thanks

          Reply
  68. Tina

    I knew it had to be the new NP when I started having flu symptoms, muscle aches, nausea, stomach ache, breaking out into hives and feeling foggy/depressed. I was perfectly fine until taking the new disgusting NP. It’s scary the effect the new formula was having on me.

    Thankfully, I have a couple months supply left of the good formulation to take until I figure out what to do next.

    My question is this… If I wanted to get back on synthetics how would I go about doing that? Would I take my last NP dose and the very next day start on the synthetics? Or would I need to wait a day or two before starting them?

    My other question is how long does it take to start feeling somewhat normal on synthetics?
    I ask because in the past I have tried getting back on synthroid and I felt very ill with severe anxiety and depression and sinking feeling in my stomach.

    Reply
    • Janie Bowthorpe

      Hi. Yes, we move to the equivalent amount of both synthetics. The way to figure that out is by this formula: one grain equals 38 mcg of T4 and 9 mcg of T3. So if one is on two grains right now (which is rarely optimal), they would move to double of each. Etc. Just remember to do labs along the way get optimal: https://stopthethyroidmadness.com/optimal

      Reply
      • Tina

        Thank you so much for your reply, I really appreciate it. I have so much respect for you and what you do for the thyroid community! Your knowledge on this topic is truly invaluable.

        May I ask what your preferred treatment is now that NDT has become completely unreliable? Would synthetic t4/t3 be your first go to, or Thyro-gold? Is Armour any good at this point?

        Reply
        • Janie Bowthorpe

          Hi Tina. I’m still pondering. Have my husband on Thyroid-S and he’s doing so much better on it. I might even go that route as I don’t have issues with fillers. Or I’ll do Thyrogold, or T4/T3. I could even add T3 to Thyrogold. Lots of options to ponder as I use my formerly good NP up. As far as Armour, it’s the only one we wonder about. But again, seem to see too many having problems getting up to optimal. It’s a hard call honestly about Armour.

          Reply
          • Tina

            Ok I see. Where do you get thyroid-s from? As far as thyrogold goes how would you dose that?

    • Janie Bowthorpe

      Oh and remember: this is not about just being on T4. We always do better on both T4 and T3…then getting optimal.

      Reply
  69. Darlene

    It was so difficult getting Naturethroid that I switched to NP Thyroid last year. I didn’t notice a change in how I felt, although it was an awfully stressful year so would I have been able to tell if it was that anyway. The last refill I got had that awful smell but the one I picked up today does not seem as bad. The pills say 330.

    Reply
    • Ryan

      Do the pills look discolored, or are they a solid color?

      Reply
    • Darlene

      Reply from Acella:

      Good afternoon Darlene,

      Thank you for contacting us! As you know with a natural product such as NP Thyroid, there will be slight variations from batch to batch. We did change API suppliers so that we can ensure that all of our consumers who rely on our product, are able to receive it. Even changing suppliers, we continue to use the same exacting quality control process and rigorous testing that we always have so that we can ensure the product delivers the appropriate amount of T3 and T4. We have received feedback from some patients, on the smell, and again being that the product is a natural product there will be slight variations.

      I hope this helps!
      Thank you!!!
      Quality Assurance Specialist

      Reply
  70. Ryan

    I was thriving off NP thyroid 1x 15MG 1x 60MG daily, and was able to skip a day between doses without feeling like garbage. I can’t even avoid feeling like garbage on the day I dose. I do recall feeling this way when I converted from Naturethroid to NP Thyroid against my will, but I have little hopes for the same outcome. I also spoke to Steve from Acella after I left a complaint through their website, and while his demeanor was polite, his questions and directness were cold and calculated. I’m sure he’s doing several of these calls a day but wouldn’t admit to that being the case. In any event, I gave him my info, and he wants to collect some of the pills for testing purposes, which sucks since I don’t even like stomaching the idea of dropping one of these suckers in the sink by mistake to avoid shelling out $37 for a full refill. Literally more expensive than viagra at this point. My 15MG tabs appear to be the old version, oblong shape, no speckles or blotches, no fishy or rancid smell, and I’m not feeling entirely like I’m without my dosage. I’m hoping Naturethroid magically jumps back to life here so I can go back on my single dose 81.25MG and stop with this circus act going on in the NDT world.

    Reply
    • Janie Bowthorpe

      So far, RLC seems to be doing the same thing Erfa did after their pills went south…nothing.

      Reply
      • Ryan

        I guess we’ll have to wait and see. Naturethroid is almost back in full swing according to their site and even with the introduction to their reformulated pill during their amateur-pharmaceutical-meltdown, I did ok. I switched to NP purely because it was a crapshoot whether I’d be able to get NT at any given refill, but I did enjoy the reduced cost (at the time) and the ability to skip a day somehow while on NP. Hoping they change things back or fix whatever mistake(s) they’ve created here. Not being a backed FDA drug means they can sink or swim, and there’s nothing they can fallback on if their customer base picks up and moves elsewhere. Speaking of the FDA, they e-mailed me back saying NP is out of their control since they aren’t approved by the FDA. So their hands are tied.

        Here’s their reply:
        Thank you for writing to the Division of Drug Information in the FDA’s Center for Drug Evaluation and Research (CDER).

        We are so sorry to learn of your experience, and we appreciate that you chose to share your concerns with us.

        It is important to note that NP Thyroid does not appear to be an FDA-approved drug. To see the marketing status of a drug product, visit http://labels.fda.gov, search for the product and view the Marketing Category in the last column to the right.

        Since 1962, drugs marketed in the United States have been required to demonstrate both safety and efficacy in order to be legally marketed. Don’t assume a drug is FDA-approved because your doctor prescribed it or your pharmacist dispensed it. Many unapproved drugs are marketed illegally without brand names and have been available for many years, so health care professionals and patients assume they are approved drugs. This is not correct. FDA-approved drugs have been evaluated and approved while unapproved drugs have not been reviewed nor approved so neither their safety nor their effectiveness can be assured.

        At any time, a company may choose to submit an application to the FDA for the review and possible approval of NP Thyroid. The FDA can only approve those products for which applications are submitted demonstrating that a product is safe and effective for its intended use.

        To learn more visit the page Unapproved Drugs Initiative and/or view our Unapproved Drugs Video.

        Despite the information provided above, we recommend that you report your experience with NP Thyroid through the MedWatch program, a voluntary system of reporting to FDA any product problems and/or adverse effects. You may fill out the MedWatch form online or download a form and follow the instructions on page 4 to send it to us.

        Your report, along with others, is an important element in our continued surveillance of the effects human healthcare products. Thank you for making us aware of your situation.

        Reply
        • Janie Bowthorpe

          And THAT is what has been so concerning about reporting it to the FDA. But…with all of them now having gone south, what choice do we have but to report what has happened to Acella….

          Reply
  71. Stephi

    Hello 👋
    I take NP Thyroid since 5 years and order it here from Germany. I was always very satisfied with it and felt very good.
    Now I got my blood results and the first time my ft3 is very high 7,8 (2,0-4,4)
    ft4 is normal 1,36 (0,9-1,8)

    So what can I do now ?
    Wait or lower it directly ?

    Reply
    • Janie Bowthorpe

      That may be about your adrenals. Read this: https://stopthethyroidmadness.com/pooling

      FT4 is ok. It shouldn’t go higher than 1.4ish, by the way, with that range.

      Reply
      • Teri

        You cannot should blindly guess 1.4 FT4 is acceptable when we know T4 always has the risk of converting into RT3 if it doesn’t convert to T3. PLEASE PLEASE PLEASE trst your Reverse T3 BEFORE you accept ANY T4 level # to acceptable. Many of us got very very sick accepting FT4 in midrange. This is an individual disease and NO # if T4 is acceptable across the board. Do yourself and your body the favor of testing RT3!!

        Reply
        • Janie Bowthorpe

          Teri, STTM is now about 17 years of repeated patient experiences, observations, and wisdom. And on NDT or T4/T3, no one gets into trouble if FT4 is no higher than 1.4 with a range that stops at 1.7. So why would someone see RT3 to up?? Not because of 1.4 or less. It’s because of low iron, high cortisol or inflammation. And it’s also why we stress to test RT3 and treat the cause. https://stopthethyroidmadness.com/reverse-t3

          Reply
  72. Lorie

    I’ve had a rash/hives, that tends to happen when I eat wheat, for the last couple weeks or so. I haven’t changed my diet or added a new food. Wondering if it’s coming from the NP thyroid pills.

    Reply
  73. Ronnie

    I just spoke with Steve from Acella. After an email to the company on their website, his response was very prompt. He’s a nice guy and I know it’s not his fault but, I got the same answers as everyone else. They want a few of my pills for testing and, “any/all request for a replacement will be met by the same new batches being distributed now. All they did was change manufacturer’s.” Also, I went to my local Walmart pharmacist with my new batch and all he had left was a few of the newer ones that he gave me for free to see if I found a difference. He said that unless there is a recall the best he could offer me was a refund on Walmart’s pledge of purchase satisfaction. As of starting my new batch of one 90 and one 15 per day (approximately 5 days ago), I am now fully symptomatic again. It’s so heartbreaking because I was just this year optimized on NP. I am in pain now. With no thyroid due to radio-iodine I am left with few choices. Having to start all over again in the search to even feel halfway normal is cruel and unjust. All for greed and profit. It’s truly disgusting the way our world has turned out.

    Reply
    • Carlos

      Perhaps I missed something but this is the first time I’ve seen Acella mention changing manufactures not just the source of pig powder.

      Reply
      • Ryan

        Willing to bet they switched manufacturers entirely, and not just a key ingredient and something is being added as filler that throws off the mix, or the supply is being cut by more filler than it should be without Acella knowing. This is what happens when you chase profits and start minimalizing quality by going with the cheapest option, not the most trusted. This reeks of the Naturethroid debacle where they suddenly had to drop production altogether because their ingredients were “unavailable” or they had to bring their facilities up to code or whatever awful excuse they threw at us for 2 years while we suffered and begged for answers.

        Reply
  74. housemaid

    On that link to Valisure that I gave below, I just noticed something. If you scroll down, you get this information which explains why they may have found no problem with NP thyroid so far. This also answers Janie’s question about what they are testing for. It says “Current test: active ingredient, dose, & dissolution. Coming soon: allergens, microbial, & heavy metals/toxins. Can’t reasonably test: unknown or rare impurities, efficacy & side effects.”

    So, unfortunately, it seems that it would do no good to send them NP pills now. Not until they have the “coming soon” tests of microbials, which I believe NP has. I guess we just have to quit buying NDT until this bad stuff is all used up and hope they don’t buy porcine powder from the same source again.

    Janie, I am wondering what happened to Westminster Pharmaceuticals which voluntarily recalled all their NDT pills. Did they go bankrupt? Did they ever start producing NDT again? Seems like they would be less likely to ever put out bad pills again as they had to recall almost all their stock.

    Reply
    • Janie Bowthorpe

      Westminster was using a source of pig thyroid powder from China. The facility in China was inspected by the FDA, and the FDA found they failed good manufacturing practice (GMP). So Westminster had to stop using them and thus, no more NDT pills from them.

      Reply
  75. Mara

    When I took samples of the “good” pills and the cat piss pills to the pharmacist at Walmart, he refused to smell them and acted like I was crazy. I take 90mg with 15mg of NP. The last batch of 15 were OK. I asked if I could see one of the 15s he had in stock. He brought me one but would not let me hold it–I could only look at it from a distance and, of course, I could not tell anything that far away. Does anyone know if the 15mg has been affect by the change? I am thinking of going to T3/T4 synthetic. Where can I find out information about what to ask for. I had a bad reaction to levoxyl years ago. thanks!

    Reply
    • Ryan

      I found that my 15MG pills appear to be the good old batch, but my 60MG main fill was mailed out from my usual pharmacy and filled by a “Central Fill” location c/o Wal-Mart. The 60MG pills are the culprits I believe, since the 15MGs appear to be functioning normally to some degree, if not fully.

      Reply
  76. Connie Hull

    I ordered my two months’ supply of NP thyroid. OMG…it now tastes and smells like CAT PEE. Disgusting. I will be calling my Naturopath and complaining to her. I also made a complaint a few days ago to Acella, haven’t heard a thing. Typical, I guess. Have been dealing with indigestion, something I don’t normally experience. Don’t know if this is related or not. Will be taking or possibly switching to using MORE Biotics Research GTA-Forte II GREED seems to win over customer quality and service, nowadays.

    Reply
    • Mara

      How do you know how much of the MORE Biotics Research GTA-Forte II to take?

      Reply
  77. housemaid

    OK, we are going to get nowhere as long as we have no proof that anything is wrong with the current stinky NP thyroid pills. A million patients could complain and nobody will do anything without a laboratory analysis of the pills. They will just continue to blame internet hysteria. The only way I know to get this done is for somebody to get their next NP refill at this pharmacy which tests every batch of pills they sell. Since they won’t do the analysis unless you order from them, please somebody get your prescription transferred to this mail order pharmacy so they will check out the pills. They are probably more expensive, so you could just get a 30-day prescription.

    Walgreens is not going to test these pills and neither is any other chain or private pharmacy but this one. They are the ones that found carcinogens in Zantac and now countries all over the world are pulling it from their shelves. I beg somebody to order their NP pills from Valisure if only to be sure you don’t get the stinky ones that will make you sick. When you order, please tell them to check for bacteria. https://www.valisure.com/analysis/#analysis-services

    Reply
    • Karen

      House maid I asked them yesterday if they are having any issues with np thyroid and she said no so I find this very odd. But maybe if someone does use them and says please check them for bacteria or a chemical that shouldn’t be in it. I for one will not put another np in .my body.

      Reply
    • Sue

      I just talked to someone at Valisure. They will test NP Thyroid, regardless of where it was purchased. The cost to test is $40. https://www.valisure.com/analysis/#analysis-services

      Reply
      • Janie Bowthorpe

        Just an FYI: be prepared that just because they will “test” it doesn’t mean they will test for the right things or the right way…and for only $40. Be prepared that you just might get the same hoopla that all is well…in spite of the myriad of problems such a huge body of patients have been experiencing on NP Thyroid. I hope I’m wrong, but be prepared….

        Reply
        • Lynn

          Would it help if we asked them to test an old NP and a new NP? I have one old NP left that is a 15 mg and about 10 stinky NP’s that are 60 mg. Would it matter if there are different strength? I’m willing to pay to find out what happened.

          Reply
          • Janie Bowthorpe

            They seem to only test what you order from them via your prescription.

            I’m just not confident that they will know WHAT to test. There are many possible factors here.

      • Karen

        Sue I called valisure me Monday morning and she told me they will not test pills unless it is a prescription that they dispense from thier mail order pharmacy. and I agree with Janie for 40$ that doesn’t sound like a good testing . But could be wrong.Best of luck.we really need an answer

        Reply
    • Yesi

      Housemaid,
      Have you transferred your prescription to them and had it checked yet, what were the findings?

      Reply
      • housemaid

        Yesi, I bought 3 months worth of NP from Walgreens in August and it was all the bad stinky stuff. So I’ve used up the money I have for thyroid meds for awhile. I am not ordering any more NP, maybe ever, but I want to know what exactly is wrong because I suspect all of the NDT today is being made with bad porcine powder from Sichuan Friendly of China. I wonder how far in advance the manufacturers purchase the powder and when this bad stuff might run out.

        For the time being I am using a Jan. 2016 bottle of Nature-throid that I found in the back of my closet. It is working great even though expired. No bad smell or taste. Back then a year’s supply was cheap!

        Reply
        • Janie Bowthorpe

          Nothing is being admitted by Acella as to why so many of their customers have gone south on their changed pills.

          The noticeable changes are as follows:

          1. A highly stinky smell to the tablets which patients are comparing to cat piss or kitty litter. It has been suggested this horrid smell is due to whatever is used to remove the tablets from the molds. We don’t know for sure.
          2. A horrible taste to the tablets, and the removal of a sweetness.
          3. Tiny specks in the pills. These specs have also been observed in other prescription brands/pills which seem to be less effective.
          4. Different shade of color, which can be due to different batches of pig powder, but who knows.
          5. Slightly larger pills, which is stated due to a different pill mold.
          6. What what appears to be a large body of patients who have seen a miserable return of their hypothyroid symptoms. There are also some patients who reported burning down their throat, burning in their stomach, certain allergic-like symptoms, etc. As more patients are redoing their thyroid Labs on the changed NP thyroid, we are seeing reports of a higher TSH and a lower free t3, and for some a higher RT3.

          Reply
  78. Renee

    Hi everyone,
    So, I just wanted to share this story with you all. I had the most POSITIVE experience with my pharmacist last week. I called my pharmacy last Wednesday and spoke to the pharmacist and told him what was going on with Acella NP. I told him I was due for a refill, but that I had some serious concerns. I gave him the list of lot numbers that have been reported as possibly problematic, and I mentioned to him that it seemed like most of the issues were coming from lot # G and E. He said he had some pills on hand with lot #K, but not enough to fill my prescription. He said he would call the distributor. On Friday, my pharmacist called me back to tell me that the distributor sent a bottle with Lot #G. I asked him over the phone if he would be willing to open the bottle and inspect the pills. He agreed and kept me on the phone while he opened the pills. He looked and told me that they were speckled and that they had a smell of cat urine. I asked him if he could grab the pills he had on the shelf (lot #K) and compare them to the speckled ones. He did, and he told me that the speckled ones looked slightly bigger. He said the ones on the shelf were smaller and had no speckles. At that point, I told him that I am afraid to take the speckled ones as patients have reported problems with them. He said he was going to call the distributor back and order different dosages so he can put together a refill for me of good pills. I told him I don’t care how many pills I have to take a day….I just care that they are not from a bad batch of pills. He said now that he knows what he’s looking for, he will inspect the pills before he fills the prescription. I am so grateful for this pharmacist. He is really top-notch and actually cares about people! I will let you know what he ends up getting.

    Reply
    • Janie Bowthorpe

      That is very cool that you found a caring pharmacist!!

      Reply
    • Rita

      Renee, in what city is your amazing pharmacist? Is he at an independent pharmacy, or a chain?

      Reply
      • Renee

        Hi Rita,
        I’m in Connecticut. It’s an independent pharmacy, which is likely why he is more willing to listen to me. Before I transferred to my current pharmacy, I had to use my local Rite-Aid, and it was awful. They were disrespectful, dismissive, and ignorant. And now that Rite-Aid is no longer. They closed their doors, never to return.

        Reply
  79. Shauna

    I went two weeks without mine because my doctor kept ignoring the refill request and telling me they sent it.
    Had the normal symptoms of not being on it for first week and a half.
    Finally got it refilled, and I at once noticed the size was off and that it smelled like cat piss to me.
    I checked the bottle with the old one and nothing at all was different.
    I took it for 2 days, and for those two days my symptoms where twice as bad than when I’d been without it.
    I had a migraine lasting 24 hours and when it finally started letting up I took the second pill and yah it came back again. Not fun when I had to work through it both days.
    I decided not to take it on the 3rd day and felt fine again. So far I’m not taking mine, but I know it’s not a good long term solution.
    I do still have the old bottle but sadly no pills left in it, however it still smells like the old medication did. (Like fish food flakes)
    I took it back to the pharmacy, telling them somethings wrong with it, and they checked the labels on the bottle and the one on the computer and hand it back. “Nope it’s the same.”
    I know it’s the same! There’s something wrong with it! It looks bigger than before, it smells like piss, and it’s making me sick!
    Goes back to talk to someone else, comes back.
    “It’s the same prescription, I don’t know what else I can do.”
    Just smell the stuff! I brought both bottles, I can’t take that.
    Back once more opens new bottle in back, “oh I see what you mean, it smells off, but you’ll have to come back tomorrow, our managers in, we don’t know what to do.”
    Well at least it’s something.
    How do recalls happen when pharmacists just check the label and say nothings wrong with it just continue taking it?

    Reply
    • Just Me

      Report your reaction to the FDA. That’s how recalls happen. Unfortunately Acella is ignoring people. I had to report chemical burns from NP. The more reports to FDA, the more Acella has to respond and address this.

      Reply
      • Karen

        Thank you for saying report this to the FDA. I was told they are not seeing many reports on this. People are saying my pharmacist is reporting it and other people have filed one well where the hell are they going then if they actually filed it. I am really upset because they cannot justify sending some to pick up my bad pills to check them.They don’t have enough complaints. So I have been hurt by this medicine and filed proper complaint for what big fat nothing.so for everyone looking for an answer what could make you sick.you blew it through hoping accella will give you your answer. Just sit around and complain amongst each other and that will fix it. So I call bull . This is not just about you this is hurting alot of people myself personally believe in helping others even complete strangers because it is the right thing to do.

        Reply
        • housemaid

          Karen, you could send your pills to Valisure, the online pharmacy which runs tests on every prescription medicine batch that they sell. They will also do tests on pills that you send in from another pharmacy, but there is a fee for that. Because of Valisure testing Zantac and finding carcinogens in the pills, now countries all over the world are banning Zantac. However, the FDA did not ban Zantac but said it was OK.

          The FDA has also failed to remove the “”–sartan” class of blood pressure medicines even though over the last year they have recalled batches of it repeatedly. It should be noted that all batches of the –sartan drugs have the carcinogens in them, but the FDA is only recalling batches that go over a certain high limit. Remember that the FDA gets most of their money from the drug companies and they really don’t care about you. But recently, Valisure found a fourth carcinogen in valsartan so maybe now the publicity will finally result in the FDA doing something about the -sartan drugs.

          Of course, there is always the chance that the FDA will solve the problem of tainted ineffective NDT by declaring the whole class of drugs illegal. They have said many times that NDT is not FDA approved.

          I think Valisure could be the answer for us if someone will send them their bad pills and note that contamination with bacteria is suspected. I would do it myself but I don’t know how much money they would charge if the pills weren’t bought from them. I have enough of the good old Nature-throid to last me many months so I won’t be buying any NDT from them. https://www.valisure.com/how-it-works/

          Reply
          • Karen

            Thanks for the info called valisure today. They will not test pills unless it is sold through them.you made other good points also just very sick and discouraged right now

          • Janie Bowthorpe

            Just an FYI: be prepared that just because they will “test” it doesn’t mean they will test for the right things or the right way…and for only $40. Be prepared that you just might get the same hoopla that all is well…in spite of the myriad of problems such a huge body of patients have been experiencing on NP Thyroid. I hope I’m wrong, but be prepared….

        • Just Me

          Karen, we’re all upset about this. The way to get anything recalled involuntarily is to report it to the FDA. I do care about chemical burns inside my body. I don’t want to die because of a thyroid medication. None of us do. People have been reporting what has been happening to them. You can’t blame the patients. I hope you feel better soon.

          Reply
          • Karen

            Just me I am not blaming the patient I know how hard it is to deal with this disease when it goes south.I am sitting here right now with a tsh of 55 and bottomed out frees. What I am saying is that they are not getting reports at the FDA I was told this from someone handling my complaint. You can’t come on here and say how bad this is and expect to get an answer what is wrong with this medicine.Janie can’t fix this she helps alot helping people get the best treatment they can. But this is not the place to get our answer what is in these bad pills. Only the FDA can do this for us. He even said that is what you pay me to do. And yes your tax dollars pay them so use what you pay the government to do. I just get scared this is going to kill someone or do permanent dammage. I wish everyone the best through this ordeal.

  80. Kim Clarke

    (Kim, I found this in spam. So just now approved it.)

    In August I picked up my refill of 90 mg of NP and immediately when i put it in my mouth I could taste the difference. I spit it out, tried another. Went to my pharmacy and asked them to smell it, they refused looking at me like I was crazy. Finally a tech allowed me to pour water on it for her to smell and the best description is cat urine. I called Acela right away and left a message. Went to another pharmacy to have them fill the script for me. There was a back order. She smelled the script wet and she agreed with the smell but advised me to continue to take. The back order came in upon refill time and now I have been on the new formula for a month 1/2 and so upset. Hair falling out more, weight game heart palpitations and tingling and numbing body. I was on Armour until their change and on NO for about 3 years and felt great until recently. I am going to have to ask for synthetic t3 t4 combo because this stuff about the pigs and chemicals are scary. I will be calling my dr. Monday. I am just so upset. And ofcourse no call back since last month from Acella

    Reply
  81. Kim

    In August I picked up my refill of 90 mg of NP and immediately when i put it in my mouth I could taste the difference. I spit it out, tried another. Went to my pharmacy and asked them to smell it, they refused looking at me like I was crazy. Finally a tech allowed me to pour water on it for her to smell and the best description is cat urine. I called Acela right away and left a message. Went to another pharmacy to have them fill the script for me. There was a back order. She smelled the script wet and she agreed with the smell but advised me to continue to take. The back order came in upon refill time and now I have been on the new formula for a month 1/2 and so upset. Hair falling out more, weight game heart palpitations and tingling and numbing body. I was on Armour until their change and on NO for about 3 years and felt great until recently. I am going to have to ask for synthetic t3 t4 combo because this stuff about the pigs and chemicals are scary. I will be calling my dr. Monday. I am just so upset. And ofcourse no call back since last month from Acella

    Reply
    • Kathy

      Why isnt everyone filing complaints w fda???its the only way to get these people investigated. Are they really feeding their pigs chemicals and hormones? Omg I am so afraid I dont think my new pills look like either one of the above pictures. They do not smell like cat pee just maybe a icky animal smell. But there is an aftertaste I cannot describe. If noone report this and files complaints w FDA nothing is gonna change!

      Reply
  82. Yesi

    Anyone here using compounded synthetic T3/T4 with good results, if so where are you getting it from and cost?

    Reply
  83. Sue H.

    I too am pissed, I am a victim of all the reformulations that started with Armour in 2009 and followed with every darn NDT that I switched to. I just found out on October 1st about the reformulation. This is just criminal. I’ve been on NP Thyroid since September 2018 when my stock pile of the good Nature-Throid ran out. I’ve been doing okay on it, not as good as I was with Nature-Throid, but doing alright. Last week I picked up a new 3 month prescription on NP Thyroid I am set to start it tomorrow when I run out of my last batch. Thank God it is the old formula. I called my pharmacy today and told them I wanted to fill my last remaining 3 month prescription, I did so in hopes of getting more of the good stuff. My husband picked it up for me and when he brought it home I checked my pills, the bottle consisted of a little more than half of the good formula and the rest being the new stuff. I went to the pharmacy and asked to be sure if they indeed mixed and old bottle with a new bottle, the answer was yes. I told them what was going on and the pharmacist said she noticed they were different. I agree, they smell like cat urine. The pills I get are 90’s, I also have a script for 15’s so I can add when I feel I need a higher dose, they were out of those so, they ordered some, they are certain that their supplier will still have the good batches. I hope so because I’m going to buy them all. Right now I have a 4.5 month supply. I hope and pray they figure it out by then because NP was my last resort. I took some pretty clear pictures if anyone would like to see them. Or if allowed I will post them on here. We are all in this together and I hope we get good answers and Acella get’s their shit together.

    Reply
  84. marianne conlin

    I recently refilled my NP Thyroid 90mg, there is an awful odor and taste to the pills. Since taking the pills I have been sick with migraine and flu like symptoms.

    Reply
  85. Karen

    You have asked if it has effected the frees. Well it has mine bad. My new ft3 on September 24 is now only 1 yes you are reading it right. Ft4 is only 0.4 tsh is 44. It was like I was taking nothing.i was not optimal but the ft3 fell from 2.4 on a dose increase in four weeks. To say I don’t feel good is an understatement! I am now using tirosint sol I cannot take synthetic t3 at all. So this scary to wonder if I can get my t3 up into safe range at this point. I am beyond angry how this drug has hurt me. My stomach is so bad I am in pain everyday. I wish everyone the best of luck. I am not done fighting to get an answer to what was in this crap that could hurt so many.

    Reply
  86. Sue

    I sent Acella a message through their Contact Us portal on their website a couple of days ago. Much to my surprise, today I received a call from an Acella Medical Info Technician as a follow up. He asked me quite a few questions regarding the smell, lab result info, and my symptoms from the last refill I got in July. He asked permission to contact my Pharmacy so they could obtain the lot number, and also asked if I would be willing to send in my stinky pills so they could evaluate them. I agreed to both. He also asked if I would like a replacement for the stinky script, which of course I said yes. The technician said they would send the replacement script to my pharmacy and then my pharmacy would contact me. Someone from Customer Service is supposed to contact me to arrange sending my stinky script back to them. I asked if he could tell me which country in Europe the porcine is being sourced from, and he said he would escalate the question to see if he could get an answer for me. I also asked if they have resolved their issues, and all he could say was that they are not admitting any problems, but are acknowledging that their source changed to Europe. I was happy that they actually reached out to me and appear to be looking into the issues everyone is having with the latest batches of NP Thyroid. Keeping my fingers crossed they can get this problem straightened out for everyone!

    Reply
    • Di

      Sue, good luck, but they have called many of us with the same questions and promises.
      It is all rehearsed.
      Only time will tell if the company is really looking into the problem.

      Reply
    • Just Me

      Sue, I’m not surprised at all. It seems they’re running scared because so many of us have had to report physical injury from NP to the FDA. Be cautious. Many have reported almost exactly what you have been told and they sent the same bad pills. I truly hope you receive a good batch, but I don’t trust them anymore.

      Reply
  87. Angela Frye

    Also want to point out that NC Hog farms suffered pretty heavy losses in livestock after both Hurricane Matthew and Florence.

    Reply
  88. Sue

    My last refill of NP Thyroid smelled awful also. Just had my labs done, and sure enough my TSH is creeping up, T3 went down slightly and T4 stayed about the same. Also having hair loss and heart palpitations. I checked with a compounding pharmacy and asked where they source their porcine from. I was told that they believed all compounding pharmacies can only get porcine from the wholesaler PCCA for product coming into the US. They believe the porcine is coming from China through PCCA. So I am steering clear of compounds because I don’t want porcine from China. I am going to try to increase my dosage of NP Thyroid and retest in about 8 weeks to see how it works. I too had been on WP Thyroid before it became unavailable and had good results with it. Then changed to NatureThroid, and went hypo, and have been on NP Thyroid doing just fine until my last refill in July.

    Reply
  89. Tracy Long

    I posted previously about having recently switched to Amour when I tried to pick up my NP prescription and it was noticeably different. I am wondering now about investigating compounding pharmacies in my area. Can anyone help me know what questions I need to be asking when I call? Do I just ask them if they use NDT in their compounds? I am just thinking my doctor will be slow to increase my amour if I need it after switching, and if I can get the dosage I need compounded maybe that will save me in the long run. Suggestions are welcome.

    Reply
    • Zhanna Tarjeft

      I inquired with the local compounding pharmacy (Gilbert, AZ) and the pricing is generally around $75/90-day supply for an equivalent of 120 mg NP Thyroid. I did take before Armour instead of Nature Throid when that went bad and in my case, it was enough. In comparison, Armour without insurance costs $120-140/90 days. 🙁

      Reply
      • Tammra

        Can you share the compounding pharmacy in Gilbert Az?

        Reply
      • Ronda

        WITH good insurance, that is the same price for a 90 day supply for me. My pharmacist said it’s because Armour is the “Name brand” and insurance wants me to use generic. Is that true?

        Reply
  90. Karen

    Angela here is something to look up. The pigs are fed feed with a drug in it called ractopamine. I read a few studies online about this.very scary because one of the side effects is major cardiac issues only the USA allows this drug other countries have banned it’s use amazingly one is China. So if you look it up lots of info online. Because you are what you eat. So it would make sense it would be great in the thyroid gland also. I know after reading about I was scared and angry.just trying to make sense of this nightmare and find some answers.Be sure to read the human study using this drug.oh one of things I found very interesting was the side effect found in the pigs was it caused peptic ulcers. Low an behold burning stomaches complaints from people including myself believe me I had ten ulcers at one time and this feels just like it.and thank you Janie for letting us vent on here.

    Reply
    • Angela Frye

      Karen, I did look at this…thanks for making me aware. A couple of the adverse affects listed were exactly what I was experiencing…The cardiac/BP symptoms were exactly what I was experiencing, including some palps..only difference was I was getting about 2 hours after administration…Also, the behavioral changes listed were VERY similar to what I called “feeling at loose ends”…the Wiki article describes it as “restlessness, apprehension, and anxiety”…https://en.wikipedia.org/wiki/Ractopamine#Adverse_effects

      Reply
    • Angela Frye

      …I’ll include our concerns regarding ractopamine with my FDA complaints, if form allows…In the meantime, it looks as if we need to do a petition to the FDA specifically regarding the use of this additive…Also, I did manage to find this letter from a Consumer Advocate group to the FDA on ractopamine. https://advocacy.consumerreports.org/research/cu-letter-to-fda-to-revoke-approval-for-use-of-ractopamine-in-pork/

      Reply
      • Angela Frye

        Also found this article from “Salon”..which mentions, among other things ractopamine’s propensity to collect in organs…Interesting that Smithfield, purchased by a Chinese company was going ractopamine free…likely that farms they owned were impacted by both hurricanes (Southeastern VA/North Carolina). https://www.salon.com/2013/11/01/is_this_meats_most_dangerous_additive_partner/

        Reply
        • Ronda

          How do you know that the ratopamine Is added to Porcine powder? Are you saying it is added only in the US? If that is true would that mean that the new Europe source for NP is not permitted to add it bc other countries besides the US including China do not allow it? If that is true then wouldn’t the new WP porcine powder from Europe not contain it? Sorry, just a little confused about this drug in our medicine.

          Reply
          • Angela Frye

            Ronda..Nobody has suggested that ractopamine is “added to porcine powder”. Ractopamine is a feed additive that is used to promote “lean pork” that is allowed by several hog/pork producing countries, including the U.S., so it may be reasonable to suspect that it’s a contaminant of porcine thyroid powder…We have no idea, without input from these same manufacturers whether or not the dessicating or manufacturing process removes the potential ractopamine. To get a list of countries that allow it as an additive, you can do a Google search. Also use the links Karen and I provided to read more about ractopamine.

  91. Karen

    Angela here is something to look up. The pigs are fed feed with a drug in it called ractopamine. I read a few studies online about this.very scary because one of the side effects is major cardiac issues only the USA allows this drug other countries have banned it’s use amazingly one is China. So if you look it up lots of info online. Because you are what you eat. So it would make sense it would be great in the thyroid gland also. I know after reading about I was scared and angry.just trying to make sense of this nightmare and find some answers.Be sure to read the human study using this drug.oh one of things I found very interesting was the side effect found in the pigs was it caused peptic ulcers. Low an behold burning stomaches complaints from people including myself believe me I had ten ulcers at one time and this feels just like it.and thank you Janie for letting us vent on here.

    Reply
  92. Catherine

    I experienced severe enamel loss on my front teeth when on NP thyroid over the course of the summer. I would run my tongue over my front teeth and taste a sharp acidic taste. I originally took the pills sublingually and then changed to orally swallowing them in July out of fear but it made no difference.

    I switched to compounded NDT powder 2 weeks ago. The sharp acidic sweet taste is gone when I run my tongue over my teeth. I hope the process has stopped but I am left with permanent damage which has affected the quality of my life. I am distraught.

    I had not had heartburn symptoms and so had not caught on. The only thing I can surmise is that my stomach acid was extremely low. Has anyone else experienced this?

    Reply
  93. DelAnn

    Yes, as soon as I saw Accella post the sourcing from Europe and FDA inspection, All kinds of questions went thru my mind too. Of the many countries in Europe, which one is the sourcing from? Where and what is the name of the facility that is actually processing, raw pig thyroid into desiccated powder? I did wonder about the FDA inspected “facility”, which lead me also to the Europe MRA thru research. The European Union, is kinda their FDA and, quote: “The Mutual Recognition Agreement (MRA) between FDA and European Union allows drug inspectors to rely upon information from drug inspections conducted within each other’s borders.” unquote. Generally speaking, If I understand it correctly, in layman’s terms that’s kinda like “ok, I’ll take ya word for it” when their product reaches our U.S pharmaceutical company here in the U.S as being a good passed inspection product, and vice a versa. Which reminds me of the recent China thyroid pill recall mess. It’s also very concerning to me, if you have little children on these crappy new batches along with the elderly, they may not be able to communicate properly their side effects, the smell and taste, other than to be fussy and refuse to take it because “it stinks and tastes horrible”, and when parents, or caregivers insist, and the symptoms arise again of hypo, and possibly becoming really sick, sick from whatever is wrong with these new pills, they end up taking them to the doctors with aliments they may not recognize as hypo thyroid related because, “well, they been taking their thyroid medication”. and then all kinds of unnecessary testing and money being spent. Kinda like Accella is ignoring the smell, taste, and returning symptoms complaints by saying, Just swallow it! I do think this needs to be reported to the FDA for the safety and sake of ours and others health.
    I tell ya, we are all arm chair speculators, but at least when our lives are at stake we tend to be pro active in finding answers, possible solutions, and stimulate the minds to research as much as possible, since the pharmaceutical companies won’t tell us anything. And THANK YOU JANIE for giving us a form where we can vent, support, emphasize and share with others our dilemmas, thoughts, pains, and hypothyroid problems! Yes Janie, we have to “Stop the thyroid madness”!

    Reply
  94. Karen

    Great comment Delann because bacteria can really mess up your stomach as it has mine.I took eight tabs a day to get my dose and each time I increased it got worse my levels are really hypo worse than before np. AS for the FDA I have filed a complaint and they are very concerned because of my symptoms I had after talkingthe pills. But what really concerns me is people on here being told to not trust the FDA and to hide thier source of where they obtain the ndt . Bill at the FDA said they are not getting many reports filed which is crazy seeing how many people are becoming sick. You don’t need a petition to file just file one for your self and the more they get the better this very serious what has happened.I for one will not just sit back and go on these forms and just talk and not take action. Promoting not filing a complaint is dangerous to a persons health. Bottom line thier be is something very wrong with this medication.

    Reply
  95. Angela Frye

    So, like so many here, I am at wit and rope’s end when it comes to dessicated thyroid replacement. In the interests of keeping my comment germaine to this post, I’ll just simply comment on my NP experiences since late March 2019. Prior to that time I’d done “okay” on NP (since the RLC debacle) noticing that my RT3 tended to be a bit higher on NP, but to be fair had a reactivated mono infection during that time also. At the end of March on a new fill, I, while working in the yard, had a “palpitation” incident. HR climbed into the 160’s and 170’s…That was the beginning of my problems with NP and I’ve found that the NP batches since that time have ranged to okay to problematic, with me experiencing elevated or erratic HR with some batches. ..(.Same with Naturethroid…some fills have been fine..some sub-par…some too strong.) Now, interestingly enough, TODAY as I went to see whether there were new posts or comments on old posts on NP’s Facebook page, just as with RLC, I have been prohibited/blocked from comments, apparently by NP (no option exists for me to comment or reply). A company that blocks comments (and believe me when I tell you, I was late to the party when it came to realizing negative NP experiences) is not interested in communicating with its patient base and is engaged in “damage control”, IMHO. Also..it is very concerning to me that there are a number of people reporting cardiac symptoms on their NP fills and as far as I’m concerned, that crosses the proverbial Rubicon when it comes to FDA reporting. NP first, as did RLC, claimed that they had made “no formula changes’ to their medication. As I have said SO many times (and as was borne out in this instance), “no formula change” does not equate to “NO CHANGE” and here is the direct quote from their “NP Thyroid Product Updates” link…”We recently changed suppliers of the active ingredient in NP Thyroid® in order to meet the increasing demand of patients who rely on our product. This has resulted in slight cosmetic changes to the appearance and size of the tablets, but it is important for patients to know that our formulation has not changed. The only difference is that the Active Pharmaceutical Ingredient (API) is now sourced from an FDA-inspected facility in Europe instead of our former supplier in the U.S.” … My questions are as follows: When was this change made? Why was it made? Why were patients not informed? Where/who is this supplier? What is the actual current active ingredient? Porcine? Bovine? Synthetic T3/T4? As of late 2017, and perhaps coincidental to this entire debacle, the current Administration’s FDA now does NOT inspect many EU facilities, but recognizes their ability to inspect themselves under something called “Mutual Recognition Agreement”. In my mind, there are countries whose regulatory protocols and inspection processes are trustworthy and those that I would most definitely question…IOW, there’s a vast difference in Germany and the Netherlands and Belarus or Slovakia, for example. (I’ve provided a link to the “Mutual Recognition Agreement” found at FDA.gov). I have to say I had not planned (I was the author of the moveon.org petition to RLC) to also petition Acella, but now, with their removal of my ability to comment on their Facebook page, I most definitely will…And I also have to say that it is preposterous to me that a company who has made such a significant change has chalked all this up to, according to Karen also commenting here, some sort of social media “hysteria”. I mean, really…they’re perfectly aware they made a significant change, do they honestly believe that the patient experiences subsequent to that change are merely coincidental? Ridiculous. Finally, I think it’s time, since it is painfully obvious that these companies are less than interested in hearing from many of us, much less owning up to, addressing, and correcting the problems, that we report our concerns to the FDA. Not sure we have any other option..and some of the experiences reported here have gone way beyond the inconvenient and troublesome to potentially dangerous.

    Reply
    • Starr D.

      Hi, Angela. Sorry to hear about your NP palpitations–just
      wanted to say that from my last NP refills in July, it seems
      like some of the pills of the 1 GR and 1/2 grain really hit
      me too hard–gave me heart-pounding, and higher pulse
      than I should’ve had at my Dr’s visit in early September.
      (blood pressure was OK, but my pulse didn’t feel like it
      came back to normal until I stayed off all the NP for a
      couple of days.) Currently, I’ve been on nothing for a
      few days as I try to get more of the NP out of my system.
      Talked it over with my doctor–he thought I should give
      Armour one last shot (because the natural meds have
      helped me with some excessive bleeding problems
      and giving me more helpful ferritin readings), but if
      that doesn’t work, it’s back to synthetics. It really was
      weird that some of the pills in my last bottles of NP
      were helpful, but others seemed like I’d end up in
      the Emergency Room if I kept taking them. Best to
      you, and I will probably report this to the FDA in the
      near future….I’m an old customer of theirs, having
      reported in various changed versions of Synthroid
      and Levoxyl over the years–I’m sure they’ll be SO
      happy to hear from me, once again!

      Reply
  96. Dawn

    (I just found this in Spam. Sorry about that. I’ve found a few this past week.)

    http://chng.it/WtFqQ8CVLp

    Janie,
    I started a petition on Change.org. I hope this link works. Please post it, so everyone can sign. I hope I was articulate with my writing. I am suffering due to not having my accurate thyroid dosage. Thanks for all you do!!! Please know, you are truly appreciated and we are all truly grateful for all of your hard work for us!

    Reply
  97. Loren

    Maybe get a petition going then report the rancid smell and taste to FDA to get them to look into this and to make sure there is NO deaths as a result of these fillers.

    Reply
  98. Betty

    Any suggestions on what to take ? Just started taking the new NP and can not stand it. Was on it for over two years and feeling great, not now.

    Reply
  99. DelAnn

    Well, Well, Well, Looks like Accella, due to so many complaints, finally had to admit they did “change” something, Their SUPPLIER. With a change in the source of the pig extract it does open up a new thought process of what has happened to the “new NP pills”. Let’s consider the 4 main complaints of these new pills. They are a different size, color, horrible odor, and hypo symptoms are returning. Recognizing all of those variations, I believe the “REAL PROBLEM” lies with the smell , and potency. To me this is strong indication that this newly sourced pig powder from “European sources” has been rendered “inactive” somewhere in the processes of traveling down the road from the live pig, to the bottle the pharmacist hands you. Bacteria causes stink. Ever put a tomato on the counter, after a few days and as it went bad it produced a smell to warn you “I’m rotten, throw me out”. That smell is bacteria growing. If you could first get past the Stink of that tomato, Would you still eat it and get sick, and expect to get the nutritional value it’s intended for in the first place? A neglected cat urine filled litter box soon emits a strong ammonia smell. Most complaints say this “new NP” smells like a litter box/ Cat-P… Just Like that rotten tomato, Cat-P ammonia smell is a result of bacteria growth, and bacteria growth can happen to an animal sourced raw product too. One of the most important issues to investigate in rendering a product inactive is to look at the source from all angles, including now from a new European supplier. Fluctuating temperature, moisture, heat, time setting in warehouses and travel times all of which can all affect the active ingredients, along with of course, knowing First, how, when , where and who processed the pork extract. Within days hours, days, or weeks, the pork can be compromised in a number of ways and lose its potency. For those reporting “It feels like I’m taking nothing”, Your probably right, at this point, you are taking nothing with these “new NP” pills in the way of receiving active T4/T3. To summarize: In my opinion, it would make sense that the smell in the “new NP pills” is coming from bacteria growth in the desiccated pig powder and that bacteria is making the ingredients in- active. I don’t care how many abbreviations , API, GMP, FDA, that Accella puts in front of statements. Bottom line is, Accella, If you start your processing with a bacteria inactive pig extract powder, it’s gonna come out a Stinky inactive product in the end! Plain and simple. And, all indications are that that is exactly what is happening. I suggest Accella needs to do some heavy investigating concerning this new supplier, especially if all these bad batches have been produced since switching to it. To the supplier, Where are they buying their porcine powder, how it’s being processed and what are their storage, handling, and warehouse conditions as it sits for shipment that could be allowing for a pungent bacterial growth smell in turn rendering the active ingredients inactive leaving all us thyroid patients sick. Based on what I have just written about, I believe all batches should be recalled at once, and the “pig” source/supplier and all the variables I’ve mentioned be investigated!

    Reply
    • housemaid

      DelAnn, I went to Acella’s website and saw their Q&A. They do admit to getting their porcine powder from a new source in Europe which they claim is FDA inspected. I wonder if they mean Eurasia as in China and Sichuan Friendly Pharmaceuticals! The FDA recalled that Chinese porcine powder last year but admitted that it was not all labeled Sichuan Friendly. So it could have been sold to some supplier in Europe and resold to the American NDT companies. But none of the companies like Acella and RLC Labs are admitting that anything could possibly be wrong.

      The smell in my bottle was not noticeable when I first got it. It sat for a month and now stinks to high heavens. That means the bacteria are continuing to multiply in the bottle. Their website says that people have reported a different taste, but that it is not meant to be chewed and should just be swallowed! They act like the taste is just a minor normal variation instead of strong enough to gag you.

      I will never take another pill from Acella. You are right; it is the same as eating rotten food. It is bound to make you sick sooner or later. But Acella says if you get sick while taking their medication, go see your doctor. Yeah, rack up big bills for doctor visits and blood tests and have your doctor tell you to take Synthroid instead. If anybody does go back to their doctor after getting sick on NP, please take your bottle of pills with you and let your doctor smell it.

      Reply
      • DelAnn

        Hi housemaid:…… Accella statement: “We recently changed suppliers of the active ingredient in NP Thyroid® in order to meet the increasing demand of patients who rely on our product.” What is interesting to me is “increasing demands”. Sometimes, that can mean acquiring a material at a cheaper price, with compromised quality. Is the raw material from EU supplier cheaper? Just my speculation, but With increasing demands, I doubt they will go to a high priced source. And what happened with the US supplier anyway? At least the NP Pills from previous years had no to little complaints. I’ve learned thru the years, that pharmaceutical manufacturing companies seldom will tell the tales of their operations. All we can do is speculate as to what they are doing… Yes, I would agree that your bottle that sat for month and now stinks is bacterial growth putting out the stench… Those little microbe’s are just having a party multiplying. I’ll tell ya this, If something stinks so bad that I can’t stand the smell, I’m NOT gonna swallow it! Especially just to cover up the in your face smell of it as though it doesn’t exist. A slight difference in smell is just that, “slight”. This is over the top…This is bacteria smell! The arrogance of the statement to go see your doctor if the medication makes you sick is total Company IRRESPONSIBILITY. And yes, everyone that does go to the doctor from being sick on their new pill should send the bill straight to Accella!

        Reply
    • Betty

      Mine does not stink.

      Reply
  100. Betty

    On their website they are telling why the pills are different. They say that their are only cosmetic changes and the main ingredient is being bought from Europe. I would like to know what the cosmetic changes are.

    Reply
    • Lynn

      Aren’t ingredients from Europe usually better? Could this be what is going on with Naturethroid as well? Have more people been complaining about NP and that forced them to fess up?

      Reply
      • Just Me

        Lynn, no. Not when it’s literally burning the alimentary canal, causing a return of severe hypo and people being physically harmed. “Europe” can be a vague statement which hides where the actives come from. They may just be a warehouse and porcine thyroid is coming from other countries. It’s a cop out. Acella has been caught and I suspect they think issuing the “Europe” statement is to appease. It doesn’t. They aren’t being honest.

        Reply
  101. Judy

    (Judy, this went into spam. Just found it. Yes, a lot have seen the below. It fails to cover many topics.)

    Did you see this on the NP website https://npthyroid.com/product-updates/
    (and based on what people are saying, obviously the sourcing of the active ingredient makes a difference, though the companies can’t seem to realize that, and they kept people guessing about the medication changes until they posted the update on their website):

    We recently changed suppliers of the active ingredient in NP Thyroid® in order to meet the increasing demand of patients who rely on our product. This has resulted in slight cosmetic changes to the appearance and size of the tablets, but it is important for patients to know that our formulation has not changed. The only difference is that the Active Pharmaceutical Ingredient (API) is now sourced from an FDA-inspected facility in Europe instead of our former supplier in the U.S.

    We continue to use the same exacting quality control process and rigorous testing that we always have to ensure NP Thyroid® delivers the appropriate amount of T4 and T3 (the active ingredients that help patients manage their hypothyroidism and associated symptoms).

    Every batch of NP Thyroid® released to the market must meet the same quality and testing standards whether it was produced using ingredients from our former supplier or our current one – and that will never change.

    We are proud that thousands of patients choose NP Thyroid® for their personal wellness and we are dedicated to ensuring they have access to the high-quality and cost-effective medicine they need and expect.

    We want all patients dealing with hypothyroidism and associated symptoms to find the best medicine for them. Patients, medical professionals and other stakeholders can contact us with questions or comments at info@acellapharma.com or 1-800-541-4802.

    Answers to Questions We’re Hearing
    Why do the NP Thyroid® tablets look different?
    We recently changed suppliers of the active ingredient in NP Thyroid® in order to meet the increasing demand of patients who rely on our product to help manage their hypothyroidism and associated symptoms. As a result, patients may notice slight cosmetic changes in the appearance and size of the tablets.

    Did you change the drug?
    No, our formulation has not changed. The only difference is that the Active Pharmaceutical Ingredient (API) is now sourced from an FDA-inspected facility in Europe instead of our former supplier in the U.S.

    Why did you change the source of the ingredients?
    Patients are at the center of everything we do. And we changed our sourcing in order to ensure patients who rely on NP Thyroid® for their personal wellness have access to the high-quality and cost-effective medicine they need.

    Are you still manufacturing NP Thyroid® in the U.S.?
    Yes, we are. The only difference is that the Active Pharmaceutical Ingredient (API) is now sourced from an FDA-inspected facility in Europe instead of our former supplier in the U.S.

    Tell us about your quality control process. Has anything changed with the update?
    No, we continue to use the same exacting quality control process and rigorous testing that we always have to ensure NP Thyroid® delivers the appropriate amount of T4 and T3 (the active ingredients that help patients manage their hypothyroidism and associated symptoms).

    Every batch of NP Thyroid® released to the market must meet the same quality and testing standards whether it was produced using ingredients from our former supplier or our current one – and that will never change.

    I’ve heard the pills taste differently too.
    The pills are meant to be swallowed, not chewed. We highly encourage everyone to abide by the prescribing instructions on the label.

    What should I do if I don’t feel well or experience negative physical symptoms?
    You should contact your medical professional.

    We want all patients dealing with hypothyroidism and associated symptoms to find the best medicine for them. Patients, medical professionals and other stakeholders can contact us with questions or comments at info@acellapharma.com or 1-800-541-4802.

    Where can I get more information?
    Please visit http://www.npthyroid.com, contact us at info@acellapharma.com or call 1-800-541-4802.

    Reply
  102. Dawn

    What if we start a Change.org petition? This might draw attention to journalists, reporters, any one who would be able to help spread the word of this disaster. Just a thought. I am sick about this, sick that I have to worry about my health, my family, my job, my sanity…Something has to give.

    Reply
  103. Cindy

    NP just posted something on their facebook page about the change. They say that the source of supply is now Europe instead of the US. They claim nothing else changed and they still have the same rigourous testing blah blah blah.

    Reply
  104. Beverly

    I’ve taken NP for 3 years now. I’ve stabilized and become “optimal” entirely due to this medication. But that being said…. since August of this year I’ve noticed the old hypo thing has returned. Hair thinning, belly bloat, etc. I flipped over to STTM to check in and wasn’t surprised to see the discussion on this product. I can’t believe that all this work to stay healthy has the skids….just because of this medication and product change. But it’s true. The tabs are visibly different, I feel bad, and that is the fact. What now….

    Reply
  105. Terri Dyke

    In Jan 2019 I changed over to an integrative, functional medicine doctor, hoping (and praying) to get some answers. So after paying over $500 on a very expensive consultation and a few labs, I was prescribed NP Thyroid and a prescription weight loss pill. I’ll admit I initially felt some marked improvements on the NP thyroid. But I did not tolerate the phentermine due to anxiety and heart flutters.
    Anyway…I actually started feeling better on the NP and continued to improve until around June-July. Something was WRONG! Talk about confused and DEPRESSED! All the symptoms, weight gain, fatigue, sinusitis, achy joints, mood swings…you name it! They all returned! I didn’t bother going back to the functional medicine doc for fear he’d charge me a lot more money, and only raise my dosage, or even worse, say it was my imagination and offer anti depressants…

    Reply
  106. Ann

    Hi All,
    Just received my new blood work after being on the bad NP (didn’t realize until I read this post). On Old: tsh .03, t4 (1.2ng/dl), t3 (3.4pg/ml). Since being on the new: tsh .01, t3 has dropped to 3.1 and t4 remained the same @1.2. Interestingly my thyroid antibodies have started to drop after being steady for over a year at 500ish. I can’t say I felt great on the old formulation. I have suffered with a lot of anxiety that I never had before starting NP. New formulation at this level has just bought a few more of my symptoms back. Hope this helps.

    Reply
  107. Marilyn

    Personally, I see this as a message from big Pharma and insurance companies..as if
    to say ” We told you to buy our Synthetic, maybe now you’ll listen!

    Reply
  108. Michelle Kaplan

    I thought I was crazy. I noticed it too, but now it’s been a few weeks and I get mine at Costco…but I’ll try and call.

    Reply
  109. Betty

    I hate talking to some pharmacists. Just got off the phone from optumx and trying to get the lot number. She started to ask me questions and I told her. When I told her about the pills, how they looked and the bigger size, she said as long as the numbers are the same they are the same. The manufactuer has not changed them. I told her I have been on thyroid pills for over 30 years and yes they do change them without telling people.

    Reply
  110. Karen

    Ok new labs drawn on September 24. Tsh 45 ft4 .5 ft3 not resulted yet. It is like I wasn’t taking anything. This on a dose increase 120mg.so for those asking it it is effecting the frees yes it is my last free t3 went from 2.3 to 1.4 on my last labs so I am sure my results from September 24 are not going to be good.

    Reply
  111. Donna Allgaier-Lamberti

    I have not noticed any visual changes in my WP Thyroid pills but I have had some alarming changes physically My goiter is back (after being 100% gone. I have had two nodules but have been stabilized now for several years.) And my weight went up about 10 lbs for no other reason that I can find, same eating (Autoimmune Protocol), same exercise patterns, etc. My emotions, I am watching now….

    Reply
  112. DelAnn

    For what it’s worth, In researching machinery in the Pharmaceutical industry, I Thought this might shed some light on just one aspect of these “new NP” pills concerning the discoloration. quote: “One of the most common causes of dark spots in tablets is a result of a contaminant, typically a tooling lubricant such as oil or grease, being transferred to the powder. Formulation can become overworked during standard operation of a rotary tablet press, resulting in dark specs within tablets. Punch tip to die bore clearance can also play a role in the appearance of dark spots on or within a tablet. If an existing tooling set begins to produce tablets with discolored specks over time, there is a chance the tooling has experienced significant wear to the punch tips and/or die bore. This wear allows particles to migrate in-between the tip and die bore and become scorched due to the friction generated by punch movement, Burned material from within the bore or from a punch tip can flake off during manufacturing and find its way into the formulation prior to final tablet compression.” unquote… To me this indicates a Quality Control problem. Isn’t it thought provoking that Accella just placed an ad position opening for Quality Control Manager at the end of August and all the bad batches started showing up a few months before that posting with brown specks, and other problems? In my opinion, it sounds as though someone in Accella’s Quality Control department was falling asleep at the wheel for several months from not following the guidelines from GMP on machine “cleaning and maintenance”, that is, IF indeed the brown specks are actually coming from bad machine practices. Accella also has an opening ad placement for “Document Control and software administrator” which could indicate, to me anyway, they may be having some “issues” in their company with not only documenting aspects of machinery problems but other operational problems as well. Quoted from another pharmaceutical guidelines article which stated, “It is obvious that Without adequate evaluation and proper perspective, the consequences may include destruction of entire lots of product, potential product recalls, loss of public confidence / damaged brand image, and possibly litigation.” … I think this is where Accella could be headed. Humm, I wonder, when was the last time their company machines and operations were inspected? I also wonder when was the last time that company was inspected in order to see if they are meeting all the GMP guidelines for the pharmaceutical industry considering how these latest batches of pills for months are not working out!

    Reply
    • Katrina

      Very clever DelAnn! The same problem occurred when the Canadian thyroid became ineffective after moving their plant from Belgium to Spain. Spots, taste, etc. I think you may be on to something.

      Reply
      • DelAnn

        Yes, Katrina, I remember well, the Erfa mess. Once they moved their facility everything went downhill. I got along well on the Erfa and hated it when that happened. And now sourcing from Europe begs some answers to a couple questions concerning this current problem. Accella’s statement: “The only difference is that the Active Pharmaceutical Ingredient (API) is now sourced from an FDA-inspected facility in Europe instead of our former supplier in the U.S.” My question is, Which “country” in Europe are you sourcing the API from? , Accella also says ” It is now sourced from an FDA- inspected facility in Europe.” My question is: Is that our U.S FDA inspectors that inspect the API at the facility or is Accella relying solely on the Europe Union inspectors doing the inspections?

        Reply
    • Ana

      Great information. That’s a very plausible explanation for what happened. That might help everyone who’s experienced burning sensations throughout their digestive tracks to figure out what they’ve been exposed to. Thanks for posting it!

      I’ve also wondered if the Quality Control Manager quit because she was being pressured to compromise standards in Acella’s quest to expand operations.

      Acella’s also clearly terrified of being sued. That in itself is evidence they knew they had done something wrong. The statement posted on August 30 was probably written by their lawyer, and everyone in the company was then coached to repeat that there is no change. To admit their pills are tainted, that they were negligent, would make them liable. They no doubt thought they were being smart, but it was a huge miscalculation. It just served to alienate all their now former NP Thyroid users.

      Reply
    • Dawn

      Thank you for this valuable insight, DelAnn. I don’t think it’s a coincidence that now Acella has these job openings after producing tainted pills. I wonder if there’s a way to find out if they cleared this issue up. Thanks again for posting this!

      Reply
      • DelAnn

        Ya know Dawn, The company will throw out explanations to us the consumer in hopes something sticks that will make sense and satisfy us as explanation of a bad product, like the standard statement of ” nothing’s changed”, then with being continually hammered by complaints, throw little tid bid of information to finally admitting the change of sourcing from Europe. On the other side of the equation are us the consumers’ throwing out our “speculations , ideas, and possibilities” as to what might be happening and hoping something in the information will stick And, will stick enough to cause a plausible reason/possibility that the company may take into consideration to explore. That’s all we can do if we are not chemical engineers, pharmacy manufactures, learned in the workings of pharmaceutical practices and operations. It’s sad actually that we are in the position we are in now with another desiccated thyroid product that is not working. We are all in this together, the Company and us the consumer. I have no thyroid gland. I have to replace the thyroid hormones in my body to live. When these type situations like with Accella’s product fail me after working so well, yes, I go into a panic mode of what could be the problem, and offer up what I hope is intelligent opinions and avenues of research possibilities to explore.

        Reply
      • DelAnn

        Ya know Dawn, The company will throw out explanations to us the consumer in hopes something sticks that will make sense and satisfy us as explanation of a bad product, like the standard statement of ” nothing’s changed”, then with being continually hammered by complaints, throw little tid bid of information to finally admitting the change of sourcing from Europe. On the other side of the equation are us the consumers’ throwing out our “speculations , ideas, and possibilities” as to what might be happening and hoping something in the information will stick And, will stick enough to cause a plausible reason/possibility that the company may take into consideration to explore. That’s all we can do if we are not chemical engineers, pharmacy manufactures, learned in the workings of pharmaceutical practices and operations. It’s sad actually that we are in the position we are in now with another desiccated thyroid product that is not working. We are all in this together, the Company and us the consumer. I have no thyroid gland. I have to replace the thyroid hormones in my body to live. When these type situations like with Accella’s product fail me after working so well, yes, I go into a panic mode of what could be the problem, and offer up what I hope are intelligent opinions and avenues of research possibilities to explore.

        Reply
  113. Debbie T.

    Janie, I would love to hear how people are doing on WP Thyroid, especially those with Hashi’s like me. That’s my only other option if I don’t go back to straight t3. I’ve been taking thyroid meds since 1993. And I was wrong–I *thought* I previously tried WP but my records show otherwise.

    Reply
    • Debbie T.

      Sorry for so many posts, Janie. Saw your blog post about WP Thyroid and think I’ll skip that route. 🙁

      Do you think most do better on straight t3 or a combo t4/t3? I’ve done both and need to look at past logs & labs.

      Thanks!!!

      Reply
      • Katie

        Hi Debbie
        Please can you explain about WP as I can’t see the posts you are referring to and have just ordered WP as a replacement for NP. Did I do the wrong thing?
        Thanks

        Reply
        • Debbie T.

          Hi Katie–sorry for not replying sooner. I checked back in my journals and saw I was on WP Thyroid + Unithroid several years ago and did terrible on it. Low temps, weight gain, other issues. My GP grudgingly has prescribed T3-only (again) and I’m finishing up my good NP tablets while waiting for my Greenstone brand generic T3 to come in.

          Reply
          • Susan

            Why are you getting greenstone vs Pfizer? I have celiac and take Pfizer. Also take np. My recent batch smells of cat piss. I went back
            And smelled a coupe of bottles of a few pills I have left and they all
            Smell gross. But not strong cat pee like the batch I just picked up. My endo dumped me when I asked for a raise and told him
            The tsh is always suppressed when taking t3. He said I was hypo though I keep gaining weight. I was started on np from
            Naturethroid in June 2018 when there was a shortage and I’ve gained 70 lbs. I’ve also had rotator cuff surgery. But I hurt like I’ve never hurt which I
            Think is hypo now that I’m
            Reading. So what thyroid meds do I take and ask for? I was not good on straight cytomel-hits me fast, lasts two
            Hours. Then I’m tired. Is that one from
            New Zealand the same as say, np or naturethyrpid? I need to know what to ask for or else they will just give me only synthroid.!

          • Susan

             Why are you getting greenstone vs Pfizer? I have celiac and take Pfizer. I had called Pfizer and they told me it wa gluten free but I read it isn’t? I Also take np. My recent batch smells of cat piss. I went back And smelled a coupe of bottles of a few pills I have left and they all Smell gross. But not strong cat pee like the batch I just picked up. My endo dumped me when I asked for a raise and told him
            The tsh is always suppressed when taking t3. He said I was HYPER necqusw myntsh is very suppressed(135 mg
            Np and 25 cytomel-labs are not optimal) though I keep gaining weight. I was switched to np from Naturethroid in June 2018 when there was a shortage and I’ve gained 70 lbs. I’ve also had rotator cuff surgery. But I hurt like I’ve never hurt before which I Think is hypo now that I’m
            Reading. So what thyroid meds do I take and ask for? I was not good on straight cytomel-hits me fast, lasts two
            Hours. Then I’m tired. Is that one from
            New Zealand the same as say, np or naturethroid? I need to know what to ask for or else they will just give me only synthroid!

            I’ve also had severe pain under my ribs and even had an x Ray. I never needed Prilosec or Zantac since I quit coffee in 2011. Now I couldn’t survive without them, it does feel like my Whole body is burning up and a bad sore Throat Too. I have done the whole pepsin hcl protocol to
            Increase my stomach acid so I hate like heck having to take the prolisec and Zantac. I tried to edit my previous post but it wouldn’t load.

  114. Debbie T.

    Just want to alert people to my recent experience. If you compare brand new Cytomel made by Pfizer and generic liothyronine made by Greenstone which is a Pfizer company, BOTH have the same fillers: calcium sulfate, corn starch, gelatin, stearic acid, sucrose and talc. I contacted Greenstone today at 1-855-222-8588 and used their Pharmacy Locator Service. Someone called back later today and gave me names of local pharmacies willing to order the Greenstone liothyronine, and the names of the people she spoke with. She said she would call back in a few days to see how everything when. What good customer service!! Looking forward to putting this latest NDT debacle behind me.

    Reply
    • Debbie T.

      Sorry for typos above!! I meant “brand NAME Cytomel” and “call back in a few days to see how everything WENT.” 😉

      Reply
      • Starr D.

        Debbie, thank you for the info about Greenstone. It might help
        my brother, in the future. He’s on synthetic T4 and T3 (both generics),
        and his T3 is made by SigmaPharm. The jury is still out on how
        effective it is. I tried really hard to get Patient Assistance from Pfizer
        or anywhere for him to try the real Cytomel, but I had no luck with this.
        Actually, Pfizer has NO patient assistance program for Cytomel, although
        they do for some of their other drugs. And Cytomel can be expensive if you
        need to take a few pills each day of it.

        Although our thyroid doctor wrote a “Do Not Substitute” prescription for Cytomel
        for my brother, they just won’t cover it without a big fight. Doctor says he didn’t
        feel name-brand to generic on synthetic T3 makes much difference, but you
        never know–if this Greenstone stuff is basically Cytomel, this information could
        be helpful to many people, like my brother, who isn’t doing that great and could
        use a lot of improvement. (so could I, but I can’t tolerate Cytomel). Thanks, again.

        Reply
        • Tracy

          Just wanted to say that when I started on T3 only the pharmacy gave me the sygmapharma brand and I could tell the difference and starting feeling a bit better. On my refill they gave me Maine pharma or something like that and I could no longer take it sublingually, I started feeling awful like I wasn’t taking anything. I told my pharmacist this but they said it was the “preferred” brand of my insurance and would not get me what was working. I switched my script to a new pharmacy who has no problems getting me the sygmapharma brand and I’m doing better again. Still not optimal and looking like I will need to add an NDT to my T3 to get where I need to. I really hate feeling like a human experiment

          Reply
        • Sharon Hagen

          Starr D., I’ve been taking the SigmaPharm generic T3 for a year, ever since Pfitzer stopped manufacturing Cytomel which I was buying from Canada as it is so much cheaper and they also give you a sealed manufacturer’s bottle of 100 pills instead of 90 from an open container. I have been on Cytomel since 2009 and every time a generic was substituted without my knowledge by a pharmacy, my levels fell on the same dose and I had a return of symptoms, so I was appalled at having to go on a generic again. I chose the SigmaPharm because I’m sensitive to fillers and don’t break down forms of cellulose and the SigmaPharm fillers were the closest to the brand that I could find. I almost immediately started feeling unwell and when I had labs, my levels had noticeably fallen. I increased my T3 dose (it is well known that the FDA allows generics to be up to 15% less potent than the brand and still be called “bioequivalent,” which is a crock just to begin with) but it didn’t seem to help and my hair started falling out in handfuls ! I’d run my fingers through my hair and actual HANKS of it would come out in my hands and massive amounts came out in the shower when I washed my hair. I also developed an itchy rash in addition to feeling sluggish and mildly depressed, gained more weight, and my skin became so dry it was painful no matter how much lotion I applied. I had already had to change from the old WP + Cytomel (on which I, for the first time, experienced an almost complete return to the way I used to feel before developing hypo, this during the 15 years I have been trying to find the right medications ) and had been switched to NP + Cytomel already and gained weight back on NP that I had lost on WP, with a return of edema and a bloated abdomen and wasn’t feeling as well at all…so having to change to a generic T3 (and then gain MORE weight and feel even worse) was really upsetting. I had reserved a couple of month’s worth of Cytomel as a reserve, subbing in the SigmaPharm instead, but a couple of weeks ago I was so wretched that I went back on the Cytomel exclusively and after about a week, suddenly felt really better ! And, noticing that my stomach seemed flatter, I weighed myself, which I don’t usually do, and found I’d lost 10 lbs. I’m so glad that Pfitzer has started manufacturing 25 mcg Cytomel again, so I just ordered some from my Canadian pharmacy and they have it in stock. But gee, now I guess I’ll get to be screwed up all over again by NPThyroid by Acella. I think it’s criminal. Anyway, you might go on the PharmacyChecker website and compare prices for your brother. My insurance upped the generic T3 into the highest tier anyway and made it expensive too, so I’d rather buy the brand, especially since it costs me about the same for a year’s supply from Canada (where it’s actually manufactured) that it costs for a 3 month supply here, and I also get 40 more pills in a year for that price too.

          Reply
          • Starr D.

            Hi, Sharon Hagen, and thank you so much for taking time
            to tell me about your SigmaPharm and Cytomel experiences.
            I didn’t see this until today (Oct. 2), as my brother has had a
            couple of really bad days–and I always wonder how much the
            SigmaPharm has to do with it, and if he’d do better with Cytomel
            plus the Sandoz T4 he’s on. So, it really helps to hear what you’ve
            gone through. To be fair to SigmaPharm, it does seem to help him
            here and there, and he’s only completed six weeks on an increased
            dose of it–so, maybe things will get better for him. He needs a LOT
            of improvement, though, and my gut instinct is that it’d be a good
            thing for him to try the real Cytomel, if things don’t get a lot better.
            So, we’ll see. He needs to lose a lot of abdomen weight and get
            more energy than he has–so when you wrote that your stomach got
            flatter and you just felt a lot better with the real Cytomel, that really
            means something to me—especially because you noticed a true
            difference in about a week. I know we all might not all respond the
            same to medications, but still, what you’ve said is something for me
            to remember and use in trying to help my brother. Our money situation
            is super-tight right now regarding buying the meds–but one of my
            brother’s doctors said she’d try to work with the endocrinologist at
            the County medical center we go to and get my brother the real Cytomel,
            if he doesn’t make much progress. So, that’s good to know, I really
            thank you for sharing what you’ve been through. About NP–it’s been
            a mess for me in the last couple of months, especially, although it did
            try to help me in some ways before my last July refills. I hope they
            learn to make replacement thyroid glands, soon, because I’d love to
            have one instead of dealing with these stupid, undependable drugs!

    • Beverly

      I filled a Greenstone generic for 5mcg script this month. I’m not impressed with the product at all. King generic was the best but it’s obviously awol at this point. I haven’t called around to see if anyone is still stocking the King product or if it’s even available.

      Reply
      • Starr D.

        Thanks, Beverly, for writing about your Greenstone generic experience.
        Because of what you’ve said, I will try to fight for my brother to get
        the real Cytomel if he doesn’t do well enough with SigmaPharm’s
        generic T-3. He’s got serious Hashimoto’s and liver problems, and
        he needs the best we can get, not just a so-so or inferior product.
        I know we can all respond differently to drugs, but your Greenstone
        experience really caught my attention, so I thank you for sharing it.

        Reply
  115. Rosemary Dandaro

    I was on Naturetroid for almost 3 years, it never did too much for me, but the last 6 months I was taking it (from December 2018- June 1019) was horrible. My hair was getting so thin and falling so much that I was considering getting a wig. I found a review on Google about the product and many people were complaining about the same problems I was having, the worsening on their hypothyroid symptoms and the hair falling. My doctor suggested that I changed the medication to WP thyroid, and I am glad I did. the symptoms were almost gone now and my hair stopped falling, I hope it will help with the weight and restore my hair as it was before. Hashimoto sucks!

    Reply
    • Betty

      How long have you been on WP? I was on armour, but cost too much and it caused me to have panic attacks. I tried the naturethroid and was doing great til they changed it. Now on NP. I am still on the old pills, but will be changing to the new ones in a few weeks that I got last month. Not sure if I want to try them.

      Reply
    • Terry

      My Dr just switched me to WP Thyroid. When did you switch and how long before you noticed a difference?

      Reply
  116. Brad

    I have been on t4 for a little over a year. Haven’t felt well the entire time and just recently found this site. I am wanting to switch to NDT, but after seeing this and all the problems with other brands I am unsure what to try. Any suggestion would be welcome. I very much want to feel somewhat normal again.

    Reply
    • Debbie T.

      Brad, I’ve tried almost everything. You might do well adding some t3 to your t4–I did that for quite awhile and I think Janie has mentioned that as an option.

      Right now I’m trying to find a pharmacy within 50 miles of me who sells generic t3 made by Greenstone Ltd. which is a company owned by Pfizer (makers of Cytomel brand). Otherwise I’ll go with generic made by Sigmapharma. I think I’m done with NP.

      Good luck!

      Reply
      • Beverly

        I don’t know if it’s acceptable to name the pharmacy in our comments but there is a big box retailer that carries Greenstone.

        Reply
        • Janie Bowthorpe

          It’s okay to name it.

          Reply
          • Beverly

            Walmart pharmacy has dumped the King generic (which always worked well for me) and is using Greenstone. Call your local WM .

          • Sharon Hagen

            Beverly, Pfizer bought King Pharmaceuticals last year and then shut down production on Cytomel, which was manufactured by King as well. I wonder if they simply changed the name to that of their generic subsidiary ?

        • Ronda

          I noticed that for my body the Signa T3 was much less potent than the Mayne T3. Both are generic brands.

          Reply
  117. Tracy

    I went to pick up my prescription yesterday and it smelled awful and the pills were noticeably different, larger and speckled. After everything I read I didn’t feel comfortable taking them home. My pharmacist was able to substitute Amour. I didn’t remember seeing anything posted by people about Amour. I have been on NP since spring of 2018 when I couldn’t get my dose in Naturthroid anymore. Is Amour okay? Should I be concerned about the same issues? Also, is it an even swap or should I be looking at adjusting my dose? I am really nervous about all of this after all of the devastating effects I read. Thanks for your help!

    Reply
    • Just Me

      Tracy, I have switched to Armour. I chew it a little to break up the fillers and make it easier to digest. I also had to adjust my dose up. I am noticing that it seems to be doing fine. Not like it used to be, but it does work. For reference, I have no thyroid at all and have to take thyroid hormone replacement meds to live.

      Reply
      • Janie Bowthorpe

        This is potentially good news with so many who did awful after Armour changed. Let us know how it continues for you and if you are able to get optimal on it with the frees. The latter is important, Just Me.

        I also appreciate that you wrote “not like it used to be”. There is an occasional someone who thinks it’s bogus that anything changed.

        Reply
      • housemaid

        Just Me, Is your Armour free of speckles, cat urine odor and horrible taste? What month did you purchase the bottle you are now using? How long have you been on it? I have used Nature-throid, WP, Erfa, and NP in the past, but never Armour. If my stash of January 2016 Nature-throid does not work out, I would try at least a one month supply of Armour unless I hear bad reports about it. I just started the old Nature-throid today but am not sure how well it will work. Of course, it is way past expiration date so I may have to adjust dose upward.

        Reply
        • Just Me

          Janie, I most certainly will!

          housemaid, Armour doesn’t have the issues of ammonia smell or strange specks. It’s not as sweet as it used to be and has the classic “sweaty gym sock” pig smell, but much fainter (possible coating and MCC). I have gone through them all as well. I can tell you beyond a doubt it’s not like it used to be and I had to adjust my dose up significantly. Chewing helps break up the pills and there’s no taste. Just a powdery glob. The cost of Armour has skyrocketed and I pay out of pocket. My next refill is around 800.00. If you can, Tirosint is a filler free T4 only that you can try WITH T3.

          Reply
          • housemaid

            Just Me: Glad to hear Armour doesn’t have the ammonia problem. But where in the world are you getting your prescription filled? Have you tried Good Rx? A 90 day supply of the 3 grain size is about $112. Even if you bought a year’s supply, at a time, it should be about half what you are paying. Are you in the US? I pay out of pocket, too.

          • ana

            I’ve been on Armour for the past 2 weeks and agree with everything that Just Me describes. I took Armour from 2004 to 2015, and it has most definitely changed but seems to be doing something. I feel better on it now than I did in 2015 when I had to switch to Naturethroid, then NP Thyroid. I had been optimal on 135 mg. of NP Thyroid and am now on 150 mg. of Armour. It’s too early to know for certain, but I expect I will need to go to a higher dose. I paid $150 for a two-month supply.

          • Just Me

            ana, I had to increase past 6 grains. Cost is rising significantly because everyone is switching back to Armour. It’s not perfect and my recommendation for anyone who is switching would be to consider Tirosint/Synthroid with Cytomel/T3.

          • Ana

            Just Me, that’s discouraging info re Armour. I spoke to my doctor about trying Tirosint with Cytomel, and she said that her patients who were previously doing well on Tirosint have been having a return of symptoms and bad labs since last summer. I checked for patient reviews on various sites, and some patients are reporting the same thing there. It really makes me wonder what’s going on. By the way, the manufacturer of Synthroid, AbbVie/Abbott now also owns Armour. They acquired Allergan last June.

  118. Ana

    It’s getting hard to ignore Acella’s contempt for NP Thyroid patients. We contacted them in a good faith effort to alert them to alarming problems we were experiencing on NP Thyroid over the past few months. They responded with an official statement, posted on August 30, that trivializes our reports of serious symptoms. A few days ago we learned from Karen that Acella employees are viewing this as an instance of hysteria whipped up on social media and that they are laughing at our emails. They were clearly mocking us and not appreciating our sharp wit.

    This goes beyond being an offensive display of misogyny; our health, our lives are being harmed by Acella’s negligence.

    Yes, we thyroid patients have turned to social media, because the medical community, the pharmaceutical companies and the FDA have all failed us. We’ve been dismissed, discarded, discredited, ridiculed and left to fend for ourselves. Hence the success of STTM. Acella’s condescending, negligent behavior is just one more instance of what thyroid patients have been forced to deal with for years. I for one am done with Acella and NP Thyroid. Enough.

    Reply
  119. housemaid

    The new NP pills smell and taste very strongly like a neglected cat litter box. This is not some “minor variation” because it’s pig. There must be ammonia in these pills. The odor in my pills has gotten stronger as they sat for a month before I took the first one today. I will not take another one. One symptom of ammonia ingestion is burning of the throat and stomach. That is one of the major symptoms that people have been mentioning, besides return of hypo symptoms. The ammonia in these pills needs to be tested because ammonia can build up to a lethal level in the body. I have been on NDT for 10 years and taken several different brands, but I never smelled or tasted anything like this before. I am saving my bottle for the class action lawsuit if it is found that the porcine thyroid powder has been contaminated in some way.

    Reply
    • Di

      That is an interesting observation! I was thinking iodine of some kind,
      since the allergic reaction I had was almost identical to my reaction to
      CT scan contrast dye, which is iodine, It is the ONLY thing I am allergic to, besides a little hay
      fever.

      Reply
    • DeeCan

      That’s interesting. One of my biggest complaints with new ERFA is a burning of my throat, esophagus and stomach. Just one of the complaints, though.

      Reply
    • Shalane M Asher

      I agree with that. I have been on 2 tablets (90) daily. I would like to sue. After taking Synthroid for 45 years I’ve noticed pain in my liver, after a liver biopsy i realized it damaged my liver. I went on NP Thyroid. What a huge waste.

      Reply
  120. Robyn

    What about compounding? Is that an option? I’m on NP Thyroid and tired and packing on weight.

    Reply
  121. Debbie T.

    Well, after much thought I am thinking of explaining to my GP what’s going on with NP Thyroid and telling her I want to go back to T3 only. I absolutely cannot go through this mess again so I am NOT continuing with NP after I run out of my “good” pills. Question: Brand Cytomel made by Pfizer isn’t covered at all by my insurance and the GoodRx price for 90 days is a whopping $872 which is not in my budget. Generic liothyronine is $133 for 90 days. Have patients done okay with generic? That’s what I was on previously before switching to NP. 🙁 My GP won’t be happy but it’s MY HEALTH. I will also contact Tammy Lowe to see what she’d recommend for dosing with Thyro-gold if T3 option falls through.
    THANK YOU JANIE FOR ALL YOUR EFFORT AND INSIGHT!!

    Reply
    • Janie Bowthorpe

      Yes, even generic can work if you work to get optimal. One T3 that has a lot of negative comments is Mayne, by the way.

      Reply
      • Debbie T.

        Thanks Janie. I don’t see Mayne on GoodRx, only: Mylan, Sigmapharm, Paddock, and Greenstone. Interestingly, the Greenstone tablets look IDENTICAL to Cytomel by Pfizer. Hmmmmm…..

        Reply
        • Debbie T.

          Janie–I googled Greenstone, and the top banner says “A Pfizer Company” — woohoo! Will check local pharmacies tomorrow to see who carries that brand. I believe it’s the off-brand generic of Cytomel. 🙂

          Reply
    • Yesi

      I heard you can get a prescription sent Canadian pharmacies, and that the brand name is well priced. Going to look into it.

      Reply
  122. connie

    YES! It smells just like cat pee now! EWWWWW!

    Reply
  123. CHarlotte

    I just picked up my new script of NP last week. At first it didn’t smell any different than the old NP or taste any different. But as the week has gone on it now has started to smell very bad and tastes terrible. As it dissolves under my tongue…there is a slimy brown residue that is left in my mouth once the tablet dissolves completely. It’s almost like wet cardboard. I don’t feel any different yet…only time will tell if my numbers change. But I have been optimized on Armour and now NP since 2009…and I’m very worried that if I do start having more symptoms that I won’t be able to find anything that will work. Does anyone know anything about Thyrovanz? This will be my next go to.

    Reply
  124. Karen

    Matt I want to say I was one of the first to contact accella. I had many conversations with Steve and David and their medical team. What you say about being precise in what you say is correct I gave them lab results symptoms and so forth.That was over a month ago but all they kept saying is nothing changed. Well here is my own experience. I knew something was different so I got replacement pills on August 8 started them and see on August 13 ended up in the er stomach pain and nauseous high blood pressure high heart rate was erratic while on the monitor.Ekg showed pvc never had that in my life.so they couldn’t find anything sent me home.so I contacted accella again sent new batch of pills started them on September 6 by the second day I was vomiting and was experiencing allergic reaction . And yes it did effect my frees bad even on a dose increase.Two weeks off these and I am still having burning stomach like when you have ulcers. So something is in these pills that shouldn’t be.

    Reply
  125. Karen

    Ok new labs after being on replacement pills in August. Tsh 45.43. up from l7.82 ft3 1.2 down from 2.3 ft4 0.5 also down. This was on dose increase for four weeks. I know I was not optimal but it should have not gotten worse.so this tells me without a doubt something is wrong with the pills this has been going on since June.This has burned my stomach so bad it is like when I had ulcers I really wish I had stopped back in June when the pain started.as someone else commented what damage has this caused that we don’t know how to fix. I know not everyone will react like this but many are complaining about burning and stomach problems. So just a heads up if you start feeling bad as I have don’t ignore it this is hypo hell and then some.

    Reply
  126. housemaid

    Back in August I got a 3 month supply of NP in the 2 grain size. I didn’t smell anything unusual and the pill was not pinkish but white. I thought I had the good pills, but no. I took one this morning and it tasted bad. I always chew them up about 6 AM. I eat breakfast at 8 AM and the taste was still in my mouth 2 hours later. I cut one in half and smelled it. Yep, just like cat pee! I am so disappointed and refuse to take another one because I think there is something toxic in it. What a waste of money. They ought to offer refunds.

    I went searching in the back of my bathroom closet and found a forgotten bottle of Nature-throid from January 2016! That is before it went bad, isn’t it? It is totally tasteless. Do you think they would still be effective, or should I increase the dose a bit? I have enough to last eleven months unless I have to increase the dose. I had quit Nature-throid for NP because NT didn’t seem to be working as well and I attributed that to no longer being able to digest the filler. I will grind it up and add what? Sugar? Does that help?

    Reply
    • Rita

      I also went back to Naturethroid. I am increasing my dose and will have tests done on a few weeks. I chew them up and swallow them, they taste fine. I have been on them almost a month and my hair isn’t falling out anymore! So at this point I will see if increasing the dose and chewing the pills will work. Synthetic sounds like a lot of work…

      Reply
      • Janie Bowthorpe

        We’ll hope for you. When it came back, it sure was awful for a lot of people and continued to be awful.

        Reply
      • Di

        My doc. just put me on NT, too. I take it early in the morning, and chew til there is no more gritty stuff–maybe 20 minutes!
        Keep it all under my tongue, with a little bit of stevia/erythritol that comes in packets at most stores. Then I don’t eat for
        an hour or two.
        Will test levels in about 3 weeks, and keep fingers crossed!
        (I knew people who had been on the old Armour for 30 or 40 years, with NO changes or problems. Those were the good ol’ days.)

        Reply
  127. Ann

    Janie,
    I am curious…why aren’t you recommending WP Thyroid? I understand the tanking of naturethroid but on your website you say WP seems to be ok. I know they have a shortage of strengths but it looks as though you can order in the 1 grain. I am new to all this as well…if you go to synthetics what would you recommend for that (Synthroid, levo)? Thanks for all you do!

    Reply
  128. matt

    Has anyone affected felt better by increasing the dose?

    Reply
  129. matt

    For those contacting Acella, thanks. Try your best to keep this technical and professional. If you get emotional, yes, they might laugh at you. Stay in control. If you have thyroid lab tests that are now difference, tell them. Example: Saying” I feel like sh/t and this stinky stuff sucks” will not be helpful.

    Reply
  130. matt

    If would helpfull if people feeling bad on this NP posted or mentioned any changes in their latest FT3 and FT4 test (!!!) TSH is mostly worthless, cant do just that. Maybe its as simple as increasing a little. (?!) I went thru all the changes in 2009, all of them. My lesson learned; try best not freak out, your body takes time to adjust to any change which sucks.

    This has been going on a while, i’m supersized there are no answers here yet. Back in 09, everyone instantly knew what happened to the other brands as FDA made them ALL change fillers to not fall apart in the shake test. The new filler made absorbion issues. All brand but NP was not invented yet. Two brands dissapeared that year too..Major and Time Caps, both were great.RIP

    Reply
  131. Matt

    This is interesting. I have newer bottle of 60mg NP from target/cvs. I also have some remain of an old bottle last spring. Did not examine the new pills till just now. The new bottle pills look like these photos in this thread, I compared to the old ones. Old ones have sweet spell, new ones different but not as bad as some here suggest. I never take new batch’s with out mixing with the old batch, I always have my own backstock. With my mixed batch, I feel mostly the same, been taking this for a month – but mixed old with new. Ill pay more attention as to if they work sublingual or not- I take the second dose sublingual in the afternoon. Morning at waking, I just swallow the pill, no food in teeth yet.

    Reply
  132. Lynn

    I’m wondering what the recovery will be like for those of us who have been on the bad stuff. Between the bad Naturethroid (June 2019-July 2019) and the bad NP (September 2019- I think the NP I took in August was the good stuff). I just started a synthetic t3/t4 and if it is good the hope is I will feel better but is there damage to my system (adrenals etc.) from the bad stuff? If it was just useless that would be different than if it had damaging properties and we need to figure out how to heal that.

    Reply
  133. Linda Pontnack

    I have been on N P for about a year. I have been doing great until I picked up my prescription in September 2019. I tastes like cat pee and makes me want to throw up every time I take it. I called the pharmacy and they say that nothing has changed. I don’ t know what to do.

    Reply
    • Janie Bowthorpe

      Call Acella and tell them you are reacting VERY badly to the changed tablets and want them to send the former tablets to your pharmacy.

      Reply
    • Jen

      The more hypo I get, the more paranoid I get. I’m to the point where I’m wondering if this is all just a big set up from the FDA/Big Pharma to force people away from NDT and back to the synthetic crap.

      Reply
  134. Nancy Montville

    Yes, I have been miserable recently but never connected it to the thyroid. I have noticed the strong odor and my tablets read 331. My label reads Thyroid NP, not NP Thyroid and it does show Acella.

    I have all the symptoms listed in your email except migraines. I had been prescribed natural thyroid by holistic doctors for the past 10 years, all 4 brands, but am now seeing a traditional geriatric physician who relies on TSH only and would prefer that I be on synthetic thyroid, so I cannot complain to her.

    I look forward to any suggestions on trying another brand. My psychiatrist ordered an rx from a different pharmacy (had been Walgreens, changed to to Osco) but I ended up with the same pill.

    Reply
  135. Cathy

    I have moved on to compounded NDT one week ago after suffering from NP thyroid. My pharmacist compounded it with glycine but I have been suffering dry mouth at night and insomnia worse than usual.
    My pharmacist wanted to compound the porcine powder with cellulose, which I declined. He did not seem enthusiastic about compounding with dextrose either. Can anyone recommend a filler?

    Someone had mentioned Vitamin C. Acidophilus was mentioned but that is an active component so not so sure. Any thoughts?

    Thanks,

    Cathy

    Reply
    • Janie Bowthorpe

      Vitamin c is popular. Olive oil has been, too.

      Reply
      • Cathy

        Thanks Janie! I am new to compounding but this is my last shot before going to synthetic as expensive as it is. Is there a type of vitamin c powder that is more clean that I could ask for or does it not matter which one they use? Thanks.

        Reply
        • Janie Bowthorpe

          It would be a vitamin c carried by the compounder. I would ask them. 🙂

          Reply
          • Sharon Hagen

            Woodland Hills Pharmacy in the Los Angeles area (which does mailorder) sent me an email saying they can compound with brown rice powder, since I cannot break down cellulose, and that they source their dessicated pig thyroid here in the US. It’s expensive though, $150 for a 3 month supply. When I had a substitute for WP compounded at a different pharmacy when WP stopped being made, the pharmacist used cellulose and I almost immediately felt horrible. I had labs done and my FT4 and FT3 levels had fallen dramatically on what was supposed to be an equivalent dose. I was so angry, since I had told him not to use cellulose in any form. He said he “forgot.” I don’t patronize them anymore, for anything.

  136. Robert T

    First let me say I feel pretty bad and have felt this way for a long time.

    The Most recent days I felt pretty good were two years ago when I was on Naturethyroid but we know what happen there.

    Anyway, I have both kinds (maybe 3) of the NP Thyroid being discussed

    I mixed my last prescription with my next batch with out thinking so consequently I have been taking both kinds.

    Just a few days ago I separated the pills best I could and I gotta tell you, I think I feel better when I take the new stuff. It has only been a couple of days but some of my worst issues are less when I take the new stuff.

    Anybody else think this way?

    I will try to report on this later

    Reply
    • Janie Bowthorpe

      Describe what you mean by the new stuff. Are the pills super stinky? Do they taste incredibly awful? Are there specks in the pill? These represent the new change pills and we have found absolutely no one that is doing well on them.

      Reply
      • Lynn

        I have to tell you that I wonder if there is a smell difference between men and women. All of the women that I have had smell the new NP thinks it smells really bad and all the men think the old NP smells worse. Is that possible? By all I mean about 4 of each sex, not a huge sampling but not many people are game for this.

        Reply
        • Robert T

          They are described as with the photo above:
          Former NP Thyroid tablet on left. Changed NP tablet on right.

          And to tell the truth, I think the yellow ones taste and smell worse.

          I may be wrong because I am assuming that since I have far more “new” ones that they are the “new” ones. I will know more in a few days when I get the next prescription.

          Reply
  137. Karen

    Jamie also in my phone calls they are laughing at emails they are getting.so with these conversations I felt I had to report this to the FDA.I respect what you do for so many people to educate us and take control of our treatment.But in this case I felt maybe they can help us find out what is wrong and hope they correct the problem and everyone will get the good medicine that we had before.I remember the mess with levoxyl and they told us it was a plastic smell and stopped production for months.Well I searched for recalls this week on levo low and behold the FDA had a recall list and levoxyl was on it . FDA findings were suboptimal pills listed for many strength pills for the years 2013-2014. So that tells you the company lied about what was going on.I use this as an example of what we are told.and levoxyl is back on the market.again thank you so much for what you do.

    Reply
  138. Betty

    Is anyone doing well on the new NP or have they found a way to make the new pills work for them?

    Reply
  139. Karen

    Yes Janie those words straight from the horses mouth won’t say the name because I think that this blog is being read by the them.

    Reply
    • Janie Bowthorpe

      It doesn’t matter if you say a name but will leave it up to you. But if this is what employees of Acella said to you, it is disgusting.

      Reply
      • Karen

        Janiee it was David that I spoke with when he said some of the emails are funny.

        Reply
        • David

          Some of them probably are funny, perhaps by design. Some people prefer to transmit info via humor. (And are often misunderstood by others who don’t think/communicate that way.) At least he didn’t say they were ALL funny! In any case, I do hope they get this mess straightened out. My last batch reeks to high heaven but they don’t appear to be new ones. I’m about halfway through my 90 day supply, so we’ll see when refill time comes.

          Reply
          • Connie B

            I’m not having a problem with NP. I noticed a difference if they were dispensed in a regular pharmacy bottle. They seem to be affected by humidity and break down and start to smell really bad and fishy. I only take them if they were in a sealed original bottle from Acella. I don’t know if that could be the problem for everyone else but I’m not having a problem.

  140. Lynn

    What to take now!?! Since the Naturethroid went bad for me in June 2019 and I was switched to NP on August 1 which at least stopped the hair loss and improved things until I got the stinky pills on September 1st and now feel terrible and I think the hair loss is starting again. My doctor prescribed a compounded 73/t4 which I started this morning and I felt ok until about noon. Does that mean this is a bad medicine for me or could it be an adjustment? Is there an NDT that is safe to take at this point? This is kind of scary…

    Reply
  141. Judy

    The fee depends on the test you select. It’s best to call them. You can tell them what your situation is and they will tell you what test to select. Once you do that. You can order them online. You would need to register. Once test are order, they send you a kit to send the pills. Call them speak to a customer service representative. They are very helpful. I transferred my prescription last week. It’s takes a bit longer. Because of their analysis of all medication they fill. They accept some insurance very limited. I paid by credit card I will from now on have my prescription filled by them. I don’t care if I have to pay for them. I would feel a lot safer doing so.

    Reply
  142. Cherry

    I was unaware of issues with NP Thyroid when I picked up a new prescription at the end of August. When I opened the bottle I was hit with a definite odor of very strong cat urine! I called the pharmacy right away and they said to bring it back. I went to the STTM website to see if you had any news on this…wow!! I immediately contacted Acella by phone and after explaining the issue was transferred to a customer service voice mail. I left all of my information and then went to their website and emailed them. I received a confirmation that my email was received, but have heard nothing back by phone or email. Although this I the first time in four years that my NP Thyroid has had the awful odor, I have had an increase in my symptoms for some time. I quit my part time job in February because of the severity of my symptoms. The pharmacy said they were going to contact Acella with the lot number (I didn’t have the original bottle). Thanks for all you do to keep us informed!

    Reply
  143. Kristine

    I just picked up my np thyroid 120 mg and they dont smell like anything really a slight smell of idk what but they dont look like those pictures posted above not like either one so I am very confused did they change how they make them AGAIN? And yes it’s the same pills they have same codes on them.

    Reply
    • Janie Bowthorpe

      That can mean the pharmacy still has a supply of the former tablets.

      Reply
    • Betty

      Mine is the same way. The smell is like the old ones, but very light. The pills are larger than my old ones and alittle speckle. I got mine from Optum rx in the mail

      Reply
  144. Judy

    You can send the pills to Valisure. For a fee they will analyze them for you. The cost depends on the test you select You would need to register online. You can also call customer service and speak to someone, that will help you select the test. You can also transfer your prescription by calling them. If you have a NP thyroid prescription that is due for a refill. When you transfer to them and they will check the pills before mailing them to you. You get a certificate with a breakdown of what they check for. They do this with all prescription ordered by them. And yes, they do have thyroid medication. They can order for you. I checked and they do order NPThyroid This would be a good way of having the pills analyzed without having to pay a fee. It’s included with every prescription they fill for you. Check their website.

    Reply
  145. Karen

    Ok in our search for what is wrong with all ndt.I found this the pigs are fed ractopamine.to make them grow fast Google the effects it has it is pretty scary.it is band in many countries but not the USA.i for one after reading the this will eat pork.on side effect that caught my attention was burning of the throat and stomach and heart problems. Read what it does to pigs is horrible.

    Reply
    • Alex

      Karen, as long as the porcine powder came from Chine or India there were no problems with NDTS. Since the source of porcine powder comes from USA we all have the great problems with NDTS. I also have seen the documentations about pigs living and growing in USA… and even that made me scared. I wish the pigs that give up theirs thyroid for us Don’t come from USA.

      Reply
      • Julie

        I picked up my 90 day supply of NP the other day and it’s the “new” version, unfortunately. Looks and smells different, is larger and has the speckles. I called Ancella and spoke w/David who says they are viewing all complaints but insists nothing has changed. I told him obviously something is different otherwise there wouldn’t be a noticeable change in look, smell, taste and efficacy. He’s going to send me an envelope to send some in. I asked if they don’t have enough of the samples as I’ve read others have sent them in, too. I did see on Ancella’s site that they are getting increased calls, so I see that as a positive thing. Must be A LOT of them for them to post on their site, even though it still reads they didn’t change anything. I went to Walgreens to see if they had old batch and they don’t. The pharm let me look at what they have. He also said it’s very difficult for them to get their hands on any. So are they still not able to fill demand? And, if yes, does that mean they are lowering their standards in order to fill the orders? The comment above re the ractopamine scares me a lot. Are we certain that the animals used for these meds are given that hormone? How do we know? I’ll go to synthetic if they are using that chemical/hormone in the NP. David said the pigs are sourced from Europe and South America. That’s all he knew. I’m going to call him back with the ractopamine name, as I didn’t have it when I called him. This whole ordeal makes my stomach ache w/anxiety.

        Reply
  146. Sarie

    New Labs on NP Thyroid:

    I’ve been on the new NP for 3 weeks now and have been optimal a little over a year. I seemed to be one of few that wasn’t feeling any symptoms returning, etc. I feel best with my T3 slightly over range, and my Naturopath is good with that 💗 Both sets of lab results are on 5.5 grains NP Thyroid, but 2 grains of the old (good) batch, 3.5 grains new. I’m not sure what to do at this point as I feel as I always have being optimal, and so far labs are stable, although they did drop very slightly 🤔 I tanked miserably and immediately back on the new Nature Throid (4 grains) with tanked Frees and a TSH of 80, and was extremely sick. I’m going to recheck labs again in a few weeks.

    I understand that I’m not taking 100% of the new batch. But when I need 5.5 grains, I’m technically only getting 2 grains of the old, good NP. Based on my past and horrible experience with Nature Throid, I would think that only getting 2 grains of the old NP that I would still feel very sick and see symptoms return. And I would think labs would drop much more significantly with taking the 3.5 grains of the new batch that many are not doing well with. I’m monitoring myself very closely. I’m due to pick up my 2 grain prescription soon so I will be fully on the new batches. I did have a full week out of the 3 that I did use my 1 grain tablets to take 5.5 grains of the new batch. I pray that answers become clear very soon for peace of mind and the well being of all of us.

    September 2019

    Free T3 – 4.2 (2.2 – 3.9)
    Free T4 – 1.2 (.6 – 1.6)
    TSH – <0.01
    Reverse T3 (pending)

    June 2019

    Free T3 – 4.4 (2.2 – 3.9)
    Free T4 – 1.3 (.6 – 1.6)
    TSH – <0.01
    Reverse T3 – 9 (10-24)

    Reply
    • Janie Bowthorpe

      Just understand that you will eventually only be able to get the changed awful tablets. 🙁

      Reply
      • Sarie

        Hi Janie,
        Thank you 💗 Yes I’m certain my next 2 grain refill will be the changed tablets so at that point I’ll be on 5.5 grains of the new NP. After how quickly and terribly I tanked on the new Nature Throid, I guess I expected to see a more significant drop in labs/symptoms, even with taking 2 grains of the old NP as part of my 5.5 grain dose. I’m considering going to synthetic T4/T3, but my options due to cost would likely be Levo and Lio and it just scares me (even at optimal doses) that it won’t work for me. I’m probably being overly paranoid, but I was so, so sick for too many years of my life. And after getting optimal and getting my life back on NP…there’s just a lot of fear and emotion in making a change 🙁

        Reply
  147. Karen

    Well I am done being afraid of reporting this to the FDA.I called this morning and filed a report because this has done something really bad to my body.They are getting reports on np and are taking this very seriously because of the symptoms we are having.please file a report if this has made you sick. Something is very wrong with this medication . This is my life and many others that Don’t know how this could cause long term health issues.The side effects are still with me two weeks after stopping np.

    Reply
    • Sharon

      I live in Pittsburgh, PA. I went to Walmart last week to pick up my 90 day supply of NP (120mg and 15mg), and asked the pharmacist if I could smell and look at them before purchasing. I took my old NP tablets with me to compare. The new NP smelled like cat urine, very pungent and they didn’t look the same as the old ones I had with me. The pharmacist even smelled them and said they were different. He thanked me for letting him know and suggested I try and find ones like the old NP by calling other pharmacies to see if they would let me smell and check them before buying. I too like everyone else here have been through the whole debacle of changing tablets through the years and am sick of it. I read about thyrogold on your website and emailed Tammy Lowe who was very kind in letting me know how to switch and how much to take. Janie I thank you from the bottom of my heart for all you do for us. I wouldn’t have known about this if not for you. I am going to try the new supplement and begin to take my health into my own hands for once in my life as I have had enough of the way we are treated by pharma and doctors who don’t care! I feel empowered to be trying the thyro gold so I don’t need to keep relying on doctors as much and drug companies that would put your life in danger for a profit. I really hope it works, if not, I’ll never stop trying till I get there. Janie you are amazing!!!!! Thank you!

      Reply
    • Alex

      Karen, it was not a good idea to call FDA. You should have read the comments from Janie regarding FDA from September. 13 und September. 20. I unterstand it’s about our health. But what do you think FDA will do? They shut down the Acella’s production of NDT for ever. If each of us calls and writes Acella then I’m sure Acella would take a closer look on what happened to their NDT. A compliant to the FDA maybe take the last chance for Acella to correct its mistakes.

      Reply
      • Karen

        Alex I did contact accella had many phone conversation spoke to the medical Dept, even given a case #. Sent pills back.But they are still claiming nothing is wrong and in one conversation was told people are feeding off other comments and called it social media Hysteria.so I did the right thing to have this looked into.Me and many others are very ill from this medication. So it is not alright to sell inferior medication.

        Reply
        • Janie Bowthorpe

          Karen, are those the exact words that someone from Acella said to you??? That this was about “social media hysteria”??????? If so, that is total crap that they would say that when SO many patients are now doing awful.

          Reply
  148. Karen H.

    Has anyone had their stinky, speckled NP analyzed to see if there is less T3 and/or T4 than the required amount? Or if there is some sort of contaminant in the product? It would seem that starting there would at least give us some necessary information. You would think Acella would be doing this to get to the bottom of the problem and I know that several people on this site have said they sent their defective pills back to Acella. How much time do they need to get us all an answer?

    Reply
    • Dawn

      Karen,
      I brought the tainted pills to a compounding pharmacy. The pharmacist told me the only way to get a true answer is to use a machine that breaks down the pill, but it costs 5 million dollars. He wasn’t kidding when he said this. Other than that, he stated there was no way to measure what was in the pills. Maybe someone else has a different answer. It was defeating to hear this, at the least.

      Reply
      • Dee

        I heated 5 separate tablets, held with pincers over a gas flame. Here is what I observed, using a geologist’s hand lens: The tablet immediately develops shiny bubbles; the speckles are the first to burn; the cat litter smell intensifies until the center of the tablet is reached. There seems to be a definite coating, because when heated a little and broken open, the tablets show a white-ish outer shell, and the inside is like wet beach sand or brown sugar. Very shiny, although I don’t see crystals.
        When powdered and not heated, I observed a few strange fibers, like tiny threads.
        Anyone have a microscope? We have a local university with a chemistry lab. Maybe it can be further evaluated.

        Reply
  149. Jennifer Steinert

    I’m having the same issues as all of you. Had been taking Naturethroid and just switched yesterday to NP Thyroid after I noticed all my hypo symptoms returning.. Had the worst night I can remember in a long time last night….stomach pain, migraines, cold sweats, etc. I guess I’ll go back to Nature throid for now until I can come up with a better solution. My question is, have these NDTs ALWAYS used calcium as a filler? I noticed recently on the bottle of Naturethroid that one of the ingredients in calcium. However they state this on their website: “Calcium supplements, iron products, or antacids must be taken four hours apart.” Does this make sense?!?

    Reply
    • Janie Bowthorpe

      It doesn’t. And Naturethroid went south, too. 🙁

      Reply
      • Lynn

        Janie,
        Is it strange that we have a wide variety of symptoms due to NP? Is it because the pill is useless or it has something nasty in it that we are reacting to? I developed fatigue, joint pain and muscle burning, tinnitus, brain fog and hair loss after beginning Naturethroid and after starting NP the hair loss stopped but everything has gotten worse. Maybe I had a good batch of NP and then a bad batch?But other people have migraines, stomach pains, etc. Should we all have the same symptoms? How long should it take for the symptoms to get better if we find something else that works? It is scary to try something new that could go south too.

        Reply
      • Jen

        Received this as part of a response from RLC Labs, the makers of Naturethroid, when I asked about formulation changes, and specifically about the calcium:
        “No changes have been made and every batch of medication we manufacture goes through rigorous testing to not only meet but exceed United States Pharmacopeia requirements for potency and consistency. We understand your concern, though, and are happy to verify your medication’s potency by providing a Certificate of Analysis. We cannot send them to patients, but if a health care provider like your physician or pharmacist can reach out with your specific lot number, we will take it from there. Please advise that a request for a Certificate of Analysis must come from a health care professional and must include a lot number.”

        “Regarding your question about calcium, the source for the calcium on the label is dicalcium phosphate, not lactose monohyrdate. It is present in Nature-Thyroid, but not WP Thyroid. Calcium may block thyroid absorption, but usually in large amounts ~200mg or more. The quantity in dicalcium phosphate is well under 50 mg per tablet and has not been found to affect thyroid absorption as per physician reports.”
        The rest of the message is just a long winded method of again saying, “Nothing is changed, it must just be you.” *Sigh* Perhaps these companies really don’t know of changes in the manufacturing of their products, which makes me think the problem is with the source of the glands themselves.

        Reply
  150. Nicole

    Was on NT for several years and doing great until I started feeling lousy end of last year and had the labs to show it. Then I switched to NP this Spring and started feeling great again (with the labs improving also). For the last month I’ve been feeling lousy (like I have narcolepsy), and labs have gone downhill. So my plan is to try Synthroid and liothyronine together. After asking several friends, those that are on Synthroid seem to be doing well and have been for many years (even one who has no thyroid due to cancer). I am concerned about synthetic because when on Levoxyl many years ago my Reverse T3 was near 300 and had to bring it down with 20 mcg daily T3 (although Free T3 showed over the acceptable range). I guess I had conversion problems due to 1 MTHFR mutation from 1 parent. It’s been such a roller coaster. So sad we have to deal with all these inconsistencies and zero accountability from pharma! They will learn by losing our business and profits!

    I am also following the advice of no gluten and 200 mcg selenium (via 2 brazil nuts a day). She recommends no dairy too but baby steps here…and the more I cut out sugar and minimize caffeine the better I feel (probably from adrenals). I should probably also start taking magnesium again but I’ve been sleeping so much I didn’t think I needed it!

    Reply
    • Janie Bowthorpe

      Yes, you should be concerned about being on just T4. There are simply too many life issues which can cause problems with the conversion, as well as push high RT3.

      Reply
  151. Rachel Smith

    Hello Everyone,
    I cannot tolerate the latest batch of NP thyroid. Just one tablet caused me to have weird reactions. Blurred vision, headaches, and more. So I am trying Raw Thyroid, by Source Naturals, which is a very clean bovine product.

    On the label it says
    Raw tissue concentrates are made from toxin-free lyophilized glands from animals grazed on rangelands known to be free of pesticides, growth hormones, antibiotics, or chemical additives. This natural product is made without sugar, starch, preservatives, or artificial colors or flavorings, or genetically modified organisms. It contains no yeast, no soy, no milk derivatives, no wheat, and is gluten free.

    It also says it is a synergistic complex made of thyroid tissue, adrenal tissue, pituitary tissue, sinus tissue, spleen tissue, maltodextrin. (from tapioca), American ginseng.
    Other ingredients: Capsule (gelatin) magnesium stearate (vegetable source), kelp, and flogard.

    I realize that it is bovine, instead of porcine, however, a more synergistic approach, seems to work for me better in other areas. Has anyone else tried Raw Thyroid? I had thyroid cancer 9 years ago, with no thyroid left, I am having to take a lot to make up the difference, but I would with any OTC supplement. Right now I am taking 8 capsules a day, which seems like an awful lot, but I’m not sure if that’s just trying to make up for the fact that my numbers were so out of whack. Even on my previous bottle of NP thyroid, which I purchased in June, it was like there was something wrong with that bottle too. I was struggling to take the right amounts and my numbers have really been messed up. I’ve only been taking this for just over a week. So I really can’t say how well it’s working, except I do feel better. I am going to be checking my lab work in two weeks and see how my numbers look. I didn’t see this in any of the possibilities under the over-the-counter list. I went through that list and didn’t feel any more comfortable with anything I saw there. The pharmaceutical types of thyroid replacement are not an option at all. I’m Allergic to the 21st Century, so I have to be very careful about even minut amounts of chemicals or additives, that I don’t do well with, but compounding pharmacies are way out of my price range. One of the nutritionists here in Flagstaff, Arizona, said that several of the people he sees highly recommend Raw Thyroid, but he is not certain if they are just supporting a weak thyroid or not.

    Any thoughts?

    Reply
    • Yesi

      Hi,
      I also live in Az. Ive been doing research on compounding pharmacies. I did some price comparisons and talked to pharmacists at each. If my numbers are all out of whack when I get my bloodwork beginning of Oct,I’m going to ask my dr. to prescribe compounded T3/T4 from Skips Pharmacy in Florida . I already get my LDN from them and their price is very reasonable compared to many other compounding pharmacies. Under$ 65, even less depending on dosage, and price only jumps $10 per month. For myself I’m going to ask for a comparable of NP Thyroid 150, and a 60 or 90 day fill.f that’s doable for you.

      Reply
      • housemaid

        Rachel, here are my thoughts about Raw Thyroid: since you have no thyroid, it would be dangerous for you to just take a bunch of that product. It includes things you don’t need/want like spleen, adrenal, pituitary, sinus tissues! I am surprised they allow that to be sold. For one thing the pituitary and sinuses are very close to the brain and with the danger, however slight, of mad cow disease, that is just too close for comfort. You have no idea how much thyroid is in this mix. If you want to try bovine thyroid, consider something like Thyrogold. You shouldn’t have to take 8 capsules of that. You’d have to do a search to find out how much Thyrogold equals the amount of NDT you were taking before. But I really think you ought to stick to pharmaceutical products because without a thyroid, you are in dire need of thyroid meds. Not NP, but maybe Armour or synthetics because it is a matter of life & death for people with no thyroid.

        Reply
        • Janie Bowthorpe

          Housemaid, not all raw thyroid is mixed with other organs. The bottom line is to read the ingredients list carefully.

          Reply
          • housemaid

            Janie, I was talking about the product Raw Thyroid by Source Naturals, capitalized, not “raw thyroid” in general. This product does have all those extra tissues and is the one that Rachel is taking 8 a day of. I am concerned that this is a dangerous thing tor be taking since it is likely to not have enough thyroid activity for someone like Rachel who has no thyroid gland.

          • housemaid

            Janie, I was talking about the product Raw Thyroid by Source Naturals, capitalized, not “raw thyroid” in general. This product does have all those extra tissues and is the one that Rachel is taking 8 a day of. I am concerned that this is a dangerous thing tor her to be taking since it is likely to not have enough thyroid activity for someone like Rachel who has no thyroid gland.

          • Janie Bowthorpe

            Thank u for clarifying. It may not be dangerous but wouldn’t be ideal when it’s not straight thyroid.

        • Rachel Smith

          Hi Housemaid,

          I had stumbled across a site about mad cow disease, not long before I read your post. I did not want to alarm people unnecessarily, so I did not mention it out here, but I know I need to take precautions. You are correct when you say that it is a matter of life and death for people who have no thyroid. I truly do appreciate your concerns. That’s one of the reasons why I’m out here asking questions. Unfortunately, Armour and synthetics are out for me. Synthetic T3 and T4, even at optimal numbers, with everything else okay, had me literally crippled with pain. Even with massive doses of pharmaceutical pain killers, which I now thankfully do not need it all, I was barely able to walk. I spent a of time in a walker or wheelchair. I will not go back to that life. It was not a life. I thought if I included a copy of the email that I just sent to Thyrogold, it would help you to understand the rest.

          Hi Tammy,

          I was on NP Thyroid, by Acella, and cannot take the latest batch. It is not just The Wretched taste, I actually had some bad physical reactions to just one tablet. Evidently, I’m not alone. According to many of the people, who follow the Stop The Thyroid Madness site, there are some issues going on there.

          I am one of those people who are Allergic to the 21st Century! 🙂 I have found that even minoot quantities of materials, that I might be reactive to, can have devastating results. Armour has too many ingredients in it, that would cause reactions. I was on Naturethroid, before I was on NP thyroid, and did poorly when they made changes. So I am, again, looking for an alternative. I am currently taking an over-the-counter supplement called Raw Thyroid by Source Naturals which may be helping, but I have to take a lot of it, because I have no thyroid. I am concerned that all of the extra hormonal tissues it contains, are not something I need in large doses. Another concern is that the label does not say it’s strictly from New Zealand or Australia, which have very high standards of animal husbandry. I am not certain that it ever did, because I don’t have my old label, but I have been reminded about the issues, with those tissues, that are close to the brain in cattle. I saw your statement about the mad cow disease, which is why you get your products strictly from New Zealand, and that helped me think this might be a good option for me. I know it’s rare to contract that, but I seem to be one of those people that get in line when there’s something unusual going on! Most compounding pharmacies are not even trying to get the USP Thyroid powder anymore, because they’re having so much trouble with availability. Even if they do, the cost is extremely prohibitive.

          I have been looking through your site, and I like what I see so far. However, I do have a question. Can you please tell me how the bovine thyroid is harvested? I need to know whether it is Lyophilized or if you use low heat? If you use low heat how much does that affect the product?

          I would also like to know what you would suggest as a replacement level of your product? I was taking 1 1/2 of the 90 mg, or about two and a quarter grams, of the NP Thyroid.

          I cannot tell you how much I appreciate all of the information that you have on your site, especially in your question and answer section. I look forward to hearing from you!

          Lord Bless You,
          Rachel

          Reply
      • Rachel Smith

        Hi Yesi,

        It sounds like you’re a lot like me, doing a lot of research. I did call Skip’s Pharmacy in Deerfield Beach Florida and spoke with the pharmacist. Andrea. For me to get the synthetic T3 and T4 would only be about $41 a month. But the synthetic T3 and T4 actually had me, literally, crippled with joint pain. I will not go back to that. Unfortunately, to get the natural desiccated thyroid or USP thyroid Powder made up, is far more expensive. She said it cost them $1,000 for a hundred grams. They’re having a hard time finding it, so they’re just not dealing with it anymore. For me 180 mg x 30 days would be 5.4 grams which would be over $100 a month. Which is fairly typical of what I’m finding at compounding pharmacies who actually do use the USP thyroid powder.

        But thank you so much for taking the time to respond. It means a lot to me! 🙂

        Reply
        • Janie Bowthorpe

          Hi Rachel. Be aware that you could have been crippled by the synthetics because you were on too low a dose and not optimal. But hope you find the NDT compounded.

          Reply
          • Rachel Smith

            Hi Janie, I know that is true for most people, however, my numbers actually were optimal. I was on T3 and T4. I was following your site faithfully, and doing all of the at-home testing. I mentioned earlier that I am one of those people who are Allergic to the 21st Century. Some people call it, Multiple Chemical Sensitivities, others call it, Environmental Illness, especially if they are also sensitive to electromagnetic fields, as I am. But I really don’t care for either one of those terms.

            I tell people that I am Allergic to the 21st Century because it makes people smile! 🙂 Which opens a door for understanding. However, I have found that even minoot quantities of the wrong types of chemicals can be devastating for me. Literally, within a day or two, after I switched to the naturally desiccated Naturethroid, the horrifying joint pain went away, and I was able to wean myself off of all of the nasty pharmaceutical pain pills they had me on. I will not go back to that life!

            But I want to thank you again, for your care and your concern, and for the fact that you have this place, for those of us who are having these kinds of challenges, to gather and work them out together!

            You are an amazing woman!

          • Janie Bowthorpe

            Referring to the 21st Century makes sense.

          • Rachel Smith

            Hi Janie, I just wanted to let you know that I am going to be taking Thyrogold. I just got off of a conversation with Tammy and I really like what she’s told me about their product. I will check back in a few weeks and let you know how my world is doing! 🙂

          • Janie Bowthorpe

            Yes, please let me and us know. It’s been around a long time. I especially want to know what amount got your free’s to optimal, if you get there.

        • Yesi

          Hi Rachel,
          So sorry you sufferred so much with joint pain. Some thoughts on the compounded T3/T4; when compounding could that possibly take care of the filler allergy issue? From what I understand Skips only uses 3 ingredients ; T3,T4 and 1 filler of your choice. I also called Woodland Pharmacy in Ca, they do still have access to dessicated thyroid from Canada and Texas; for 135 mg for 30 days would run $80, 60 days $110, 90 days $150, and they said they can ship to Az. For filler they use Microcrystalline cellulose or brown rice flour, lactose or glycerine if any of those work for you. I am hesitant to order dessicated, because of the heat issue here where I live.
          Dessicated is heat sensitive, but Flagstaff is much cooler than Yuma.
          On another note, I too had horrible joint pain for a while. It felt like electric shocks in my hands and feet. I was able to find a dr who listened and was willing to prescribe Low Dose Naltrexone, and that has helped me tremendously, as well as bring my antibodies way, way down. I get mine from Skips in Florida at 4.5 mg.

          Reply
          • Jeanne

            Yes I, I take LDN nightly too, 4.5 mg. I feel it is a good immune system booster to help prevent a return of cancer.

        • DeeCan (I used to be Dee, but someone else is Dee now too)

          Rachel, I’m also allergic to the 21st Century. I’m not really on any ndt right now because the only one I could get was ERFA since I’m in Canada. That went South back in 2015/16. Sorry everyone is having problems in the US with their brands too now, but I’m actually relieved that it is more a widespread problem and I’m not alone. Just extremely hypothyroid and unwell, but not alone. 🙁

          Reply
          • Dee

            I’ll switch to Di if you like! There are just so many Dianes in my town!

          • DeeCan

            No Dee, that’s ok. I’ll keep using DeeCan. Thanks though. I’m a Diane too 🙂 I’ve thought for years now, since all of the companies say ‘nothing has changed’, that it has to have something to do with the pigs 🙁 and either what they are fed or medications they are being given. Anyway, that’s my two cents. One more cent: Or a complete conspiracy to get us off ndt.

  152. Vincent Jericho

    For a man of 59 I remain quite athletic. Diagnosed with Graves when 35. Radiated Thyroid. Been a fight since then. Was on Naturethroid…switched to NP about year ago. DOING GREAT!!! Then the stinky pills. Mine smelled and tasted like paint thinner. At first ok but over about 6-weeks crashed. Fortunately I have a reserve of old NP which I am back on and doing well. I called my Pharmacist and at her suggestion filed complaint with FDA. Had I known then what I know now I NEVER would have let them kill my thyroid. For me internet arrived about 5-years too late…

    Reply
  153. Liz Luber

    I, too, have been experiencing regression in various ways since the change in formulation…. I’m wondering – although it’s more expensive, is Armour the equivalent to the old formulation that we all loved and felt good on? Money aside, is it as simple as switching to the Armour brand to achieve the positive results we’d been having on the old formulation of NP Thyroid?
    I’d truly be grateful for thoughts on this – I’m struggling to accept the fact that my symptoms are returning…

    Reply
    • Janie Bowthorpe

      All the NDTs changed from the good products they used to be.

      Reply
      • Dee

        I spoke to 3 pharmacists yesterday, and also a relative who does drug testing for a large pharm. co., about how to break down microcrystalline cellulose. They have no answer. One of the pharmacists actually took out the drug info insert for Armour, and read it for me, where it states the MCC is added to INCREASE absorption! I am going to try mortar and pestle. THis is all heartbreaking.

        Reply
        • Lynn

          I tried chewing my NP tablet and felt worse all day. Was definitely a bad move on my part.

          Reply
          • Janie Bowthorpe

            The changed tablet that is thicker, way stinkier, tastes awful?

          • Lynn

            Sorry, just saw this. It tasted very bad but it would have been worth it to feel better.

          • Dee

            I was thinking of Naturethroid or Armour, which are the NDTs my doctor is
            going to switch me to. They have MCC.

          • Janie Bowthorpe

            Understand that Naturethroid went terribly south as well. Patients who got back on it when it came back out in mid- 2018 had a terrible return of hypothyroidism.

  154. Yesi

    If we decide to go to synthetic T3 T4 , can we and how do we obtain T1 and T2, or do we just have to go without ?

    Reply
  155. Kim

    I was taking Np Thyroid 60 mg tablets 3 times daily and liothyronine 25 mg twice a day.. my dr changed my meds to liothyronine 25 mg 4 times a day and dropped the np and I feel like death way worse then before I ever started medicine.. I just emailed my dr and she changed med to armour 3times a day and liothyronine 3 times a day and I pray this helps me.. At this point I feel like I’m trapped in a 90 year old body!!

    Reply
    • Sarie

      New Labs on NP Thyroid:

      I’ve been on the new NP for 3 weeks now and have been optimal a little over a year. I seemed to be one of few that wasn’t feeling any symptoms returning, etc. I feel best with my T3 slightly over range, and my Naturopath is good with that 💗 Both sets of lab results are on 5.5 grains NP Thyroid, but 2 grains of the old (good) batch, 3.5 grains new. I’m not sure what to do at this point as I feel as I always have being optimal, and so far labs are stable, although they did drop very slightly 🤔 I tanked miserably and immediately back on the new Nature Throid (4 grains) with tanked Frees and a TSH of 80, and was extremely sick. I’m going to recheck labs again in a few weeks.

      I understand that I’m not taking 100% of the new batch. But when I need 5.5 grains, I’m technically only getting 2 grains of the old, good NP. Based on my past and horrible experience with Nature Throid, I would think that only getting 2 grains of the old NP that I would still feel very sick and see symptoms return. And I would think labs would drop much more significantly with taking the 3.5 grains of the new batch that many are not doing well with. I’m monitoring myself very closely. I’m due to pick up my 2 grain prescription soon so I will be fully on the new batches. I did have a full week out of the 3 that I did use my 1 grain tablets to take 5.5 grains of the new batch. I pray that answers become clear very soon for peace of mind and the well being of all of us.

      September 2019

      Free T3 – 4.2 (2.2 – 3.9)
      Free T4 – 1.2 (.6 – 1.6)
      TSH – <0.01
      Reverse T3 (pending)

      June 2019

      Free T3 – 4.4 (2.2 – 3.9)
      Free T4 – 1.3 (.6 – 1.6)
      TSH – <0.01
      Reverse T3 – 9 (10-24)

      Reply
  156. Karishma

    There has been a discontinuation of Thiroyd (By Greater Pharma, Thailand) as told by several pharmacies in Thiland as well as supplier websites. It seems the last batch number is 1500058 with an expiry date of 06 Feb 2022. Anyone has any official word from the Pharmacy?
    Has anyone tried and recommend any other formulation after Thiroyd?
    Thanks.

    Reply
    • housemaid

      Karishma, this is very suspicious that even foreign sources of NDT are drying up at the same time all the US NDT stops working. I have heard of another foreign product called Thyroid S. I have never bought it, but I think it has a lot of fillers. If I hear that Thyroid S is no longer being made, I am going to believe this is a conspiracy!

      Reply
      • Karishma

        Seems that way! My husband even said the big pharma are not really liking it and are somehow doing this. Or it may even be a raw material problem. I have used Thyroid-S and it just didn’t work for me. I did cross check with many suppliers and even had my husband’s friend check up in pharmacy shops in Thailand. Greater Pharma has stopped supplying. Of course, now the last batch bottles are being sold at double the price by whoever has stock of it :(.

        Reply
  157. Tabby

    For those of you who’ve decided to not take NP for the time being, what are you doing instead? Janie, what are you using?

    Reply
    • Janie Bowthorpe

      I am still on the former better NP. When I run out, I am playing with different things, like both synthetics (and being optimal) or some NDT supplements like Thyrogold, etc and adding T3 if needed (to be optimal).

      Reply
      • Tabby

        Someone else has mentioned compounding the NDT with as few fillers as possible. How do you feel about that? Also, have you heard of the 15mg pills being affected?

        Reply
        • Janie Bowthorpe

          Try doing a search in this blog post and comments for 15mg. Might show it.

          Not all compounded pharmacies have NDT powder. They will compound the two synthetics. Very few have the powder.

          Reply
          • Russ

            For those of us who may have to go the compounded synthetic route, how do we get optimal?
            By tweaking the ratios of the T3 and T4 until the frees are mid-range and upper mid range? Regardless of TSH ?

          • Janie Bowthorpe

            That’s the problem with compounded….

          • Paula

            Janie, can you please explain why that’s the problem with compounded? I have never heard of tweaking the ratios of T3 & T4 in NDTs or synthetics. How would that be possible? Or by getting two different synthetic prescriptions – one for T3 and another for T4?

            I was thinking of requesting my doctor for a compounded T4/T3 prescription that would be a match to NP Thyroid 1/2 grain so I can multi-dose and increase my dosage gradually according to what my DATS and blood work show.

            Is there a better/different way to get optimal?

        • Dawn

          Tabby,
          I take the 15 mg. and yes, they are affected. I get my medicine through Express Scripts. They sent out my 90 day supply in August with the bad pills. I called them and told them I don’t feel safe taking them, and they sent me a replacement bottle, unfortunately the same. I’m sure it came from the same stock. I believe all doses of NP have been tainted.

          Reply
          • Lynn

            My doctor is aware of the NP problem. She was going to switch me to Naturethroid which is what started this mess for me back in June 2019 (I have since switched doctors because my previous doctor gave me a hassle about switching to NP and said the symptoms must be due to low estrogen and not Naturethroid going bad). My new doctor has been wonderful and is now going to prescribe a compound t3/t4 but I didn’t think to ask if it would be made with NDT powder. I guess I will find out tomorrow from my pharmacist. I think someone mentioned this before that maybe the NDT powder is the problem since Naturethroid went bad and now NP. Although I don’t remember the Naturethroid smelling bad. A friend’s doctor told her she thinks that some of the NDT medicines are coming from China on ships and that storage could be an issue resulting in contamination?

            Janie – do we think that Armour is ok?

          • Janie Bowthorpe

            It was the first that patients complained seeing their hypothyroidism come back. And there were definite visible changes to the tablet as well.

            The problem with saying it’s working is that many patients feel good before they are optimal. And they don’t realize that’s going to backfire. So we don’t know yet. We just know that it changed enough that so many patients left it.

          • Kristie

            Acella called me back tonight, basically just taking a med report on my adverse reaction to the NP thyroid. I told him the pharmacist reported it as well. They said that Acella is concerned about their customers and plans to make this right. Oooookay… will see 🤷🏻‍♀️

  158. Erin Erickson

    I switched to NP after the Naturethroid shortages and I did great. I often felt hyper on Naturethroid and I felt pretty dang good on NP and no more hair fall. My labs from six months ago looked good, my free t3 & 4 were at an optimal level. My tsh is always very low (my Doctor seems to focus more on that). I used to take NP 120 with 2 15 mg. I changed to 30 mg (take 5)..then I got the smelly batch and at first thought my allergies were the cause of the bad taste. Now I’m feeling hyper and anxious and can’t sleep. For the last couple of days, I’ve been taking four instead of the 5 30 mg NP and feel a little better (and less like a hummingbird on speed). I had labs drawn last Friday and have a Dr appointment on Wednesday..I know they’re not going to look good. I talked to a pharmacist and she suggested I wait for my labs before changing meds. The pharmacist said that she is on Armour (though not entirely happy with it) and she never liked NP. My Doctor is not totally on the NDT bandwagon, and I’m afraid he will want me to take synthetic. I don’t know what to do, what to try. Not sure I can afford Armour. I took Armour about five years ago for a short time and liked it – I remember it lifted my brain fog, an amazing feeling. Just want to feel good again! Best to everyone here in their search..

    Reply
    • Starr D.

      Hi, Erin. That’s interesting you’re having trouble with the 30 mg. NP pill,
      because that’s the ones I may be having trouble with, too–giving me
      hyperthyroid-type symptoms, while still getting a lot of low thyroid ones,
      too. I was using 1 and 1/2 per day of the 30 mg. for about 3 months–
      got a new batch in late July, and they smell OK but may be too strong,
      in some ways. (I also took a 1 Grain NP, in the morning.)

      Had an endo appointment earlier this month, and labs a couple of
      weeks before that. Was doing sort of OK until the night before
      my appointment, when I took my last dose of the 1/2 grains…
      hit me real hard–headache, neck ache where the thyroid would
      be if I had much gland left (but I don’t have much due to RAI
      for Grave’s Disease, years ago), stomach ache, and ear-ache.
      Barely felt good enough for Dr’s appointment the next day–
      blood pressure was OK, but my pulse was 100 and it wouldn’t
      come down until I went off all NP for a couple of days. Doctor
      said maybe the morning pill was OK, but maybe something
      was up with the afternoon ones (the 1/2 grains.) He said to
      keep taking the morning NP pills I still have, and maybe take
      Armour in the afternoon (he wrote a different prescription for this.)
      I’m still using up what I’ve got (found some old 1/4 grain NPs from
      January, which aren’t expired.) And frankly, it’s a mess, because
      now that I’ve had that bad episode a couple of weeks ago, I seem
      extra sensitive to this medicine in general, now, and I know it’ll be
      that way for awhile, because I’ve been through this before with
      other thyroid drugs. My labs looked OK according to the Doctor,
      and he felt there was no reason I should’ve gotten the symptoms
      I did…well, it’s either my own weird system acting up in general to
      thyroid medicine, or the NP pills themselves causing trouble.
      But I’ve quit taking the 1/2 grains, just in case they’re the problem.
      And for now, I’ve had to reduce my dose as I figure out what I can handle.

      I hope I won’t have to go back on synthetic drugs as I haven’t done
      well with them for years, but it’s an option I may have to revisit.
      The doctor is willing to work with me on whatever way I need to go.

      Janie, thanks so much for this site! The ability to compare notes with
      others, and all the info you provide, is just so useful and important!

      Reply
      • Janie Bowthorpe

        You’re welcome. Now you can see why I stuck with patient experiences and wisdom all these years. 🙂

        Reply
      • Erin Erickson

        Hi Starr, I’m wondering if the 30 mg pills are too strong. I cut back about 15 mg and have been feeling a lot better. I’m not having hypo symptoms with the icky pills, just the feeling of being over medicated. I’m also having a tightening feeling around my neck – I’m due for an ultrasound (I had a partial thyroidectomy 5 years ago). My Dr gave me a new script for NP so that I can look for a pharmacy that has any of the old batch. I may move on to Armour if that doesn’t work out. I have Hashimoto’s, so I’m not sure if that’s what is causing the hyper symptoms or the NP. Good luck in your search!

        Here’s my labs after taking the gross NP:
        tsh: 0.01 (0.4-4.5)
        total T4: 9.0 (4.8-10.4)
        Total T3: 123 (7.6-181)
        Free T4: 1.0 (0.8-1.8)
        Free T3: 3.2 (2.3-4.2)
        (it’s all my Dr tested)

        Reply
  159. housemaid

    Some people seem to be under the impression that the FDA is their friend. No, the FDA is the friend of Big Pharma only. You may be unaware that common blood pressure drugs ending in “-sartan” have been found to be tainted with a carcinogenic substance called NDMA. There have been multiple recalls of various batches of these drugs over the last year. However, most pharmacies don’t really keep track of what batch numbers they dispense when it comes to these high volume drugs, so many people with bad batches are not being notified. And the truth is that the FDA is allowing a certain amount of carcinogen in all these “-sartan” blood pressure drugs, so a person thinks their batch is OK when it really isn’t. https://www.peoplespharmacy.com/articles/popular-heartburn-drug-zantac-ranitidine-tainted-with-a-carcinogen

    The online pharmacy mentioned in the above article (called Valisure) tests every batch of drugs they sell for impurities. Valisure has found this same NDMA carcinogen in Zantac as high as 3 million ng. FDA says this is fine. I’ve never heard of this pharmacy before, so I don’t know if they sell NDT or if just anyone with a prescription could send it in to Valisure. But I looked at their website and they have a page where people can send in information about bad batches of drugs they have gotten. Maybe they would be interested in testing some of these bad NP pills. From what I have read on here, I fear these new NP thyroid pills are not just ineffective but possibly dangerous. They seem to be causing some toxic like effects such as burning when swallowing and nausea. Acella’s website says there are just minor variations in appearance, taste, and smell of NP thyroid and claim they test every batch, but I don’t feel reassured. Here is the webpage for the Valisure Pharmacy where they ask people to report a bad batch experience: https://www.valisure.com/report-bad-meds/ I assume that the bad drug did not have to come from their pharmacy, but not sure about this.

    Reply
    • Karen

      I went to that site and filled out the contact info for np thyroid. I will see if they can test this I don’t know.i have sent pills back to accella to be checked but am not hopeful.But this stuff has burnt my stomach so bad I am in horrible pain.

      Reply
  160. Ana

    I was just looking at Acella’s site and noticed that they have a job opening for a “Quality Control Manager”. The opening was posted on August 23, 2019. This makes me wonder if they fired the last one over the NP Thyroid debacle. That’s the first indication I’ve seen that they know there was a serious problem and that they’re working to resolve it. The position still seems to be open.

    And thank you, Janie, for creating this invaluable resource. STTM helped me to get optimal treatment over the years and during these past few months has been the best forum for patients to share their experiences, insights and strategies for dealing with the NP Thyroid problems. Thanks so much!

    Reply
  161. Anne

    Forget my hopeful comment below about how we have to specify Acella as manufacturer and make sure we don’t get AvKare as manufacturer. I just got back from Walgreens and they showed me it was Acella and they are the new pills.

    Reply
  162. Sabrina Schön

    Let’s trust demonstrable facts, not rumors.

    And remember this was/is an excellent product for so many of us.

    So if Acella seriously tries to clarify this, then we should have some patience to get our good product back.

    In the meantime it will be difficult for many to find an alternative.

    Some of us changed already, like I did, because I had no choice – well knowing, with all the realistic fears and facing the facts, reading all the helpful things here on STTM (thank you so much Janie).

    And what can you say after taking a new medication not even a full week? Nothing.
    And in 2 weeks? Not so much more.
    May be in 6 weeks.

    Maybe Acella has solved the problem by then.

    May be, may be, may be.

    ACELLA !! WE ARE WAITING FOR FACTS !!

    Reply
    • Anne

      Sabrina, can you share with us what you are using instead and whether it is good?

      Reply
      • Sabrina Schön

        Anne, yes, in about 5 weeks I’ll be able to tell you my experience.

        Reply
        • Lynn

          Can you tell us what you are using now and then let us know in 5 weeks if it helped?

          Reply
          • Sabrina Schön

            For the moment I try synthetic T4 and a little amount of compounding pharmacy (T3) with that.

            If that works I’ll carry on with this, if not, I will change again.
            (And, like Janie says, trying to stay optimal)

            I’m living in Europe.

  163. Terry

    I received a text from Walgreen’s that my script for NP Thyroid is ready for pickup. I called and the batch is on the bad list. Do I ask for a different refill? And if so, what do I ask for? I know I’m not feeling the greatest but thought it was the gut/mold issue I’ve been trying to resolve.

    Reply
    • Dee

      The pharmacist at my local Walgreens just told me today that Acella is not shipping anymore
      NP Thyroid to them. Is this nationwide?

      Reply
      • Terry

        That’s interesting. I wonder if my Walgreen’s might get a call from them not to dispense the NP Thyroid.

        Reply
      • Christa

        I went to fill my husband’s new script for WP again (he used to be optimal on this and loved it until they stopped producing and switched to NP – which he hated from the start) and not only did they say WP is not shipping/back ordered (this was CVS), but she also told me that he could no longer get the NP as it was noted in the computer that it is no longer shipping/unavailable. I was able to find WP at another pharmacy for the time being…..and even though many note it went downhill, he did better on WP. Sigh. So frustrating.

        Reply
  164. Karen

    Ok new labs drawn on September 13 after increased dose of np. Tsh 45.43 ft4 .5 ft3 not in yet.That is on two grains numbers are alot higher on increased dose. Not to mention horrible side effects on np.i am going to say something is wrong with all porcine powder because I did bad on compounded also.so I am going to try tirosint sol to see if I do better. Just to add my tsh on September 10 was 0.84 my Dr said something is really wrong here and wanted rechecked big fluctuations here.Hope this helps people that are not doing well on np.

    Reply
  165. Melissa

    I just received an email from Express Scripts that they are unable to fill my script for NP Thyroid!! What do I do??? I cannot take Synthroid and Cytomel, I tried that once and a lost two weeks of my life, I was in such a fog and had such horrible headaches.

    Reply
  166. Yesi

    I recived a call today from David at Accella. He promised to send new 120s and 30s to my pharmacy to replace the bad batch I have now. He said someone else would call me tommorow and that I would get package in mail to send back bad batch. It sounds like everyone else’s experience, so we will see if they follow through, and investigate as promised. Any one been on compounded T3/T4, with good results?

    Reply
    • Dee

      Steven promised to send the same here, and nothing happened.

      Reply
      • Amy Lynn

        Same story here! Multiple phone calls to Dave at Acella and a 25+minute conversation with that Steve guy in Massachusetts almost 2 weeks ago telling him everything, and I’ve got nothing…no replacement pills nor envelope to send them back. Just going to take the pills I have & hope for the best, that they got enough complaints now to fully look into it/change it back! Tried Armour as a replacement, and that was a $60 disaster. Tirosint (the best T4) out of reach for me right now monthly cost-wise

        Reply
        • Anne

          what happened with Armour?? Did it not work for you?

          Reply
          • Amy Lynn

            Anne yes, Armour did not work for me. Felt so tired/sick the one day I managed to take it. I’m on a decent dose too (3 1/2 grains.) Not only that, but I believe I also had an allergic reaction to something in the fillers, maybe? My face immediately swelled up, then my face/neck/chest got all red an hour after taking. After that a few hours later, my skin started itching all over. Not fun! I’m only allergic to sulfa drugs, that I know of. My mom and my sister take Armour seemingly without issue, but it’s not for me & my body apparently!

  167. Valency

    An update: I picked up my newest bottle and I now have the speckled pills (which smell like a littler box and taste horribel!) mixed in with the whiter, non-odorous, harder pills. I spoke with people at Acella and they are sending me an envelope to send back samples for the FDA. Let’s keep sharing as much info as we have.

    Reply
  168. Catherine

    Hi. Did anyone actually receive the return envelope in the mail to mail in the replacement medication from Acella?

    I never did. And that was after many calls to Acella and filing a report with the pharmacist at Acella. They told me they would ship replacement pills to my pharmacy and mail me replacement pills to my pharmacy. My pharmacist also spoke with them.

    I have received nothing promised and this happened back in June with the 90 MG pills of NP thyroid. At the time, I thought it was just a bad batch but now I see it was far more than that.

    After that incident I would not touch the 90 mg pills. I had my doctor order all 30 mg pills and so I took 5 a day. The experience on 90 mg pills was too severe. Looking back I should of stopped taking NP then.

    I am allergic to Armour and so I moved to expensive compounded porcine/NDT powder compounded with Gycine last week. This is my last shot at NDT as I wont touch Naturethroid with all the bad reviews or WP as it is too new after the changes made.

    I had half my thyroid removed due to Papillary cancer. I flare from levels that are off caused new swollen lymph nodes to appear back in June. That is not acceptable for people like us who are struggling.

    Reply
  169. Ginger

    I started calling Acella and left several vmails on the CS line. My last one was less than charming and I stated that I would continue to leave messages until someone called me back so I could place a complaint about tainted medication. I received a callback from a gentleman named Steven, who identified himself as one of Acella’s pharmacists. He took a detailed (but not personally invasive) report from me that took approximately 30 minutes. I advised him of color, smells and taste of the “bad” pills and the symptoms I had. He was very kind. Once we’d finished, he asked if I would be willing to send them the affected meds for analyzing. I have a new script en route from my pharmacy and told him if the new batch is also bad, I’ll reach back out and we’ll discuss me sending them some. I asked him what Acella planned to do about this as I had read multiple reports similar to mine. He said that Acella is “aware of the reports of issues with NP Thyroid on social media” and have put up a notice about that on their website but they are standing firm that nothing has changed in the manufacturing or ingredients of NP Thyroid. Okey dokey. I hung with him and followed Acella’s posted instructions to contact the FDA to place a complaint about tainted medications. Just waiting for the paperwork to come.
    I have about a month of good meds left, then I don’t know what I’ll do.

    Be well everyone,
    Ginger

    Reply
    • Janie Bowthorpe

      They “stand firm” that nothing has changed yet patients are experiencing horrible symptoms…another example of gaslighting.

      Reply
      • Ginger

        I particularly enjoyed the part about “they are aware of social media.” Well, that’s a load off my mind. We’ll all just go back to being sick as hell, you guys just keep up with your web-surfing. It never changes, does it?

        Reply
      • Dee

        Janie, I don’t think any of us should have mentioned the size, color, or smell; unfortunately, that is what they
        hung on to. My second call to Steven only emphasized the horrible allergic reactions I am having.

        Reply
        • Janie Bowthorpe

          Yes they have hung onto those three. But they also knew/read/heard about the reports of worsening hypo from many of you!

          Reply
          • Janie Bowthorpe

            And I should have added: the fact that the changed tablets smell worse than ANY NDT has ever smelled in the last 17 years, plus the patient descriptions of a horrible taste to the point of making some nauseated…underscores that many things are quite wrong on top of the massive amount of patient-described symptoms of a return of hypothyroidism in terrible ways.

          • Ginger

            A little update from me- I called Express Scripts (as previously stated) and told them what had happened. The pharmacists sent me a replacement bottle of each of the 2 dosages I take. They were both the same foul smelling bad ones. I now have 4 huge bottles of stuff I can’t take. Taking what little of the good pills I have. My dr called in a script for Armour I haven’t started yet (hey now, that’s expensive) and I’m just waiting to see what happens with Acella.

  170. Tracey

    Hi Guys,

    I recently changed to tirosint + cytomel after being forced to leave Nature Throid and now NP. I am starting to hear more and more that Tirosint has also changed manufacturers – and is no longer working for people. Has anyone had this experience with Tirosint no longer working for them? Any info on this is appreciated. Thank you!

    Reply
  171. Yesi

    I’m thinking of asking my dr to prescribe a compounded t3/t4 , comparable to the dosage of NP Thyroid I was on. Has anyone done this? Any suggestions on reputable compounding pharmacies? What type of accreditation to look for? I dont have a compounding pharmacy anywhere close to me, going to have to find one willing to mail.

    Reply
    • Lynn

      I talked to my pharmacist today and the odd thing is that when smelling the new NP thyroid (which I think is horrendous) vs. the old NP – my husband son and the two male pharmacist’s think the new one smells better than the old and my daughter and I think the reverse. They are willing to compound a t3/t4 for me. Maybe that is the way to go?

      Reply
  172. Lynn

    Another question – do we think that NP is basically a sugar pill or a pill with something that doesn’t agree with our bodies? Wondering if I am better off being hypo than with the burning, aching, ringing and extreme fatigue.

    Reply
  173. Anne

    Have you guys seen this? GoodRX NP thyroid images?
    https://www.goodrx.com/np-thyroid/images
    They say this one manufactured by Acella loks like this
    and this one manufactured by AvKare looks like this
    And they are clearly different. The one that I have that I am scared to use looks like the one manufactured by AvKAre
    Are they a generic version? It looks like we should just ask for the ones made by Acella.

    Reply
    • Anne

      Just adding to this…I called Walgreens to tell them I only want my prescription from Acella not any other company and they just emailed me to tell me it is out of stock so it is delayed. So clearly these batches are not from Acella.

      Reply
      • Anne

        and also there seem sto be other manufacturers of NP according to this
        https://www.findacode.com/ndc/drugs/NP_THYROID_60
        NDC Trade Name Labeler Name
        42192-0330 NP Thyroid 60 Acella Pharmaceuticals, LLC
        42291-0643 NP Thyroid 60 AvKARE, Inc.
        71335-0414 NP Thyroid 60 Bryant Ranch Prepack
        45865-0566 NP Thyroid 60 medsource pharmaceuticals
        51655-0132 NP THYROID 60 Northwind Pharmaceuticals, LLC
        68788-7032 NP Thyroid 60 Preferred Pharmaceuticals Inc.
        53002-1029 NP Thyroid 60 RPK Pharmaceuticals, Inc.

        Reply
    • Yesi

      I called my pharmacy and, they confirmed that my speckled, grey, stinky pills were indeed from Accella.

      Reply
  174. Hadassah

    Now that NP Thyroid is not working well . What is everyone that was dosing with NP switching to ? My pharmacist said he can not get NatureThroid . Armour is prohibitive .

    Reply
    • Rita

      I went back to Naturethroid a couple of weeks ago. I am chewing up the pills before swallowing and will get tested in 6 weeks. So far I feel ok, more energy but still some hair loss. But I have read that the hair loss won’t instantly get fixed. I am also sleeping great and no anxiety. Maybe the key to taking Naturethroid is chewing it up? Supposedly works with Armour…

      Reply
      • Michelle Sarchiapone

        I had a old 3 month supply of WP thyroid I switched to. When I run out, if the NP mystery has not been solved, I will try a compounded med.

        Reply
  175. Melanee Ables

    I’ve been on NP for several years and have always been happy with it. I was underdosed but happy overall. 🙂 I also noticed the last prescription had a foul smell and taste. So much so that I double checked the pills and felt concerned taking them. I’m on 120 mg/day. My pharmacy only carries the 30 mg pills so I take 4 . Even on that high-ish dose my labs were not optimal so my dr added Synthroid (name brand only). I think that is why I am doing well even with the change of NP. Optimal FT3 and FT4 for the first time ever.. and I’ve been on meds since 2012. All of that is to say.. sometimes synthetic is okay! I’m a huge on natural products but even my dr said some of his patients aren’t doing well on NDT alone and thrive once he adds Synthroid.

    Reply
    • Yesi

      Melanee,
      What dosage of synthroid did he prescribe?
      120 NP Thyroid + how much Synthroid?
      I’m also on 120 NP.

      Reply
      • Melanee Ables

        sorry I just saw this! I am on 50 mcg Synthroid T, Th, Sat, and Sunday and 100 mcg on MWF. I just received my first labs back after this change and I am finally in optimal ranges.

        Reply
  176. Debbie M

    I was originally on nature troid and doing well. I switched to np thyroid due to weird test results and shortage. Was on it for 4 months but too much hair coming out so decided to switch back to nature troid. Picked script up from pharmacy and checked pills when I got home they were darker with specks. Just like your description of NP thyroid. I had some left over nature troid pills from previous script and they were white with no specks. This is so frustrating! Don’t know if I should take them or take back and show pharmacy.

    Reply
    • Janie Bowthorpe

      You were clearly underdosing yourself on the former good NP. It’s an excellent product if one gets optimal on it. Optimal puts the free T3 at the top area of the range with a midrange FT4. Both.

      But if one gets the changed NP, and even the changed Naturethroid, there are consistent problems, sadly.

      Reply
      • Deanna

        I am on NP Thyroid and have been for about 2 years. But in the last few months I have had the following problems: Extremely itchy skin, red rash, profoundly tired, head aches, heavy chest and heart palpitations off and on.
        My lab results are: TSH: .82 (.40 – 4.50 mlU/L) Free T3: 4.1 (2.3 – 4.2 pg/ml) Free T4: 0.8 (0.8 – 1.8 ng/dL)
        The NP I have at this time does not have the spots on them and not a strong smell.

        Reply
        • Deanna

          To further explain my last post: I am on 120 milligrams of NP Thyroid. My endocrinologist now says, “see this is why I do not like to prescribe NDT as it is not standardized and I worry about your heart and bones”. She will prescribe NDT but is nervous about it. It is my understanding from what I read here and other places is that NDT is standardized, and is the same amount of T3 and T4 in every pill; is this correct. What does it mean when my TSH is so low and T3 is up so high. Can anyone tell me if they have experience and think that my numbers would be considered optimal. I have felt good on this amount as I said up till a few months ago. Thank you

          Reply
          • Janie Bowthorpe

            NDT has always been like any medication out there–an ALLOWED and low percentage of variation between batches. But that is not changed that we have soared on it.

            And his comment totally ignores that the US Pharmacopeia does have a standard for the thyroid powder.

            As far as your low TSH, THAT.IS.PERFECTLY.NORMAL on NDT or even T3. Doctors stupidly freak out about that, claiming bone loss and heart problems…yet we have constantly seen patients report IMPROVED bone density and IMPROVED heart function because of the direct T3.

            As far as your high FT3, that is where we are SUPPOSED to have it when optimal, along with a midrange FT4. Both. So if your FT3 is high with a low FT4, that is probably pooling of the T3 due to a cortisol problem that needs discovery and treatment. https://stopthethyroidmadness.com/pooling

            And this: https://stopthethyroidmadness.com/optimal

            We HAVE to stand firm against doctors who go by the TSH, who think we will have bone loss or heart problems, who don’t understand that it’s inadequate iron or a cortisol problem that causes issue when raising towards optimal. https://stopthethyroidmadness.com/ndt-doesnt-work-for-me

            Finally EVER SINGLE BRAND of NDT has been ruined. Every single brand. NDT used to work far better, was consistent, didn’t cause problems like it does now. So now we have the fight to be LOUD that we want to know WHAT IS GOING ON.

  177. Debbie M

    I was originally on nature troid and doing well. Switched to np thyroid because of weird test results and shortage. Was on it for about 4 months. Lots of hair coming out so decided to go back to nauture troid. Picked up script yesterday. When I got home looked at pills and they are darker with specks just like the np thyroid you describe. They have no smell though. I had some nature thyroid pills left over from a previous script and compared them to the new ones and they are white with no specks. So frustrated. Scared to use them.

    Reply
  178. Karen

    Ok this gets strange.new labs after six weeks on new doses of 120mg.only have tsh results today. Tsh 0.84 last tsh on July 31 17 lowest I have had for years.does not explain sideffects on these new pills.was taking 105mg with tsh of 17 my stomach is so inflamed I can hardly eat and my skin burns and wierd rashes.these pills do not seem consistent.will wait to see the rest of my lab results.but I have stopped np because I feel so bad even with one 15mg tablet.

    Reply
  179. Sabrina Schön

    In the StopThyroidMadness-facebook is a comment from “Rachel Librach Nisenson”, which says, that David Margolis from Acella told her on the phone, that “..the source of the thyroids are from Europe and North America..”.

    So “from Europe” seems new.

    I’m from Europe and I’m sure, that we have NO producers of desiccated porcine thyroids.

    As far as I know, there are 2 companies in Europe, one in Italy, the other in Spain, that are buying desiccated thyroids from South America, testing them and sell them again.

    Additives in desiccated thyroid like lactose, salt, sugar (and may be more?) are allowed according to USP – without need to be listed.

    So may be this change in source changes a lot?

    Reply
  180. Jennifer

    Someone asked if Armour had changed their lower strength tablets back to their old formula. I was hopeful so I called and asked Allergan (Forest Pharmaceuticals) and they said no, that all of their strengths still have the MCC. …Which leads me to wonder why manufacturers of NDT even put microcrystalline cellulose in their tablets when so many of us can’t take them after that. Does this cheap filler save them so much money that they can afford to lose hundreds of customers? I also looked up Avicel which is the trade name for this cheap wood pulp filler that is added to some drugs, supplements, and foods. What I found is that Avicel is usually imported from China and may contain Propylene Glycol, Talc,Wood Pulp, Grass, Newspaper, Lead, White food dye, Calcium and other “binders, undisclosed”. That makes it hard for me to believe that these companies are very concerned about putting out a bad pill. Is it all about the money?

    Reply
    • Starr D.

      I never understand why some companies are OK with cutting corners on ingredients, etc, when they’re making
      at least some patients sick in the process. I’ve had this talk many times with different thyroid drug companies,
      when they’ve changed their formulations (usually changing the “inactive” ingredients, which can affect how you use
      and absorb the pills.) I told one guy at Synthroid a long time ago, “Look, I’d gladly pay for the older, better version
      made before 1982-83, if I could be well again,” He said, “Well, unfortunately, most patients don’t feel that way.”
      He made it sound like their company just felt it was better to be cheap than to put out a better product. And that’s
      the way it seems a LOT of these thyroid drug companies operate. And the Food & Drug Administration basically
      has let them get away with it. I can’t say what the new FDA head would say about any of this, though, as I’ve not
      tried to contact them (yet) about any of this–though I might in the future, even about why in general they don’t
      make sure we have really good, reliable thyroid drugs we can count on, whether they’re natural or synthetic.
      In the past, higher-ups in the Endocrine dept. at the FDA have made it sound to me like they have “no power”
      to do anything to correct problem thyroid drugs that are causing some patients harm. That’s wrong. If I feel
      better soon (as I’m currently having problems with NP–not sure if it’s my dose or their medicine), I may look
      into contacting the FDA again about the safety of ALL our thyroid drugs, especially when they are changed in
      in some way. P.S. I also got extra-sick years ago when Levoxyl added microcrystalline cellulose and
      croscarmellose sodium to their their ingredients instead of some things like potato starch and lactose,
      and when Armour added microcrystalline cellulose instead of some more simple, basic “inactive” ingredient
      to its pills. It shouldn’t have to be this hard to be a thyroid patient, who’s just trying to have some decent health!

      Reply
    • Amy Lynn

      Wouldn’t surprise me honestly if they used bottom of the barrel fillers! Just tried Armour for the first time ever yesterday (it was $60 for the same 2 dosages that I’m on with NP, only a month’s supply, and that’s with with insurance) and within an hour I broke out in a red, sunburn-like rash on my face, neck, & chest. Also my skin started to itch everywhere. My mom and my sister take it with no problems, they say. Hmm. No more Armour for me though, can’t take it!

      Reply
  181. Leslie

    At the end of August with a threat of a hurricane looming over my state, I was frantically calling my pharmacy to see if the batch of my thyroid np was bad. It tasted and smelled like mold! I felt vindicated hearing the pharmacist gag over the phone after smelling the bottles. He put in a new order and encouraged me to contact the company to which I did. I left a voicemail and still have not heard from anyone.

    I have picked up a new prescription and to only have the same problem again! I wish I had seen this update before calling the pharmacist :/

    Reply
  182. Lynn

    I read the above suggestion about someone making the changed Armour work by crushing them. I just chewed up my “new” NP. How would crushing it or chewing it help it to work better? Thanks!

    Reply
  183. Angela Schuster

    I recently picked up a refill of my NP Thyroid and immediately noticed a difference in the “taste” of the tablet, almost chemical like? I even went back to look at the RX Bottle to make sure I did t accidentally take a different RX I keep in the same cabinet but use occasionally. I confirm that I did not do this and that I was taking the NP thyroid pills. I thought it seemed odd but haven’t noticed many changes if any to how I feel physically. I’m concerned though, after reading this post and seeing the comments from others in the group. I was having a hard time getting nature through aid due to shortages so switch to NP about a year ago. I go in for labs next week so I’ll be curious to see if anything has changed in the 3 or so weeks I will have been on this seemingly new formulation.

    Reply
  184. Jean

    I am very suspicious as to why every company making the pills are all changing them. It is not s common practice to change medication way back. Today, however, these pills have changed numerous times! Now every company makes a bad pill. Are the people working at making the pills aware? I would like to know what is really behind all of this. I know big pharma got Trump to change the absorption product. I think big pharma is behind all of this. Are all 4 companies ignorant to something? I’m sure they wouldn’t want to sell a bad product.

    Reply
  185. Pat Boatman

    Why am I not able to ask questions on your Facebook page? I am getting pretty desperatefir some help since I have a idiot dr

    Reply
  186. Sabrina Schön

    What do you think about getting the drugs testet by an independent laboratory?

    Reply
    • Janie Bowthorpe

      It’s being explored.

      Reply
      • Jeanne

        What about Valisure? They test every generic for contamination before filling a prescription! Your doc can order a prescription from them via EMR too. I am considering using them before my next NP Thyroid refill….

        Reply
  187. Paige

    The way you described is not what I just received my NP. It tastes like candy! So I assumed my package was older version. So what are you guys are going to do about it? If they companies won’t listen to us? How we can survive it? Most of us won’t go on chemical medication like Levo or synthryoid.

    Reply
    • Janie Bowthorpe

      It can actually be workable to be on synthetic T4 with synthetic T3 and getting optimal. Optimal puts the free T4 mid-range and the free T3 at the top of the range.

      Reply
      • Paula

        I have terrible side effects (mostly pain) with synthetics (T3 and T4) so that is not an option for me. Any other suggestions at this time?

        Reply
        • Janie Bowthorpe

          Paula, that can mean you weren’t optimal at all. Study this page: https://stopthethyroidmadness.com/optimal

          Reply
          • Rachel Smith

            Hi Paula, just so you know, I also had extreme pain when I was taking the synthetic medications. I have problems with just about every synthetic medication that I have tried. I believe that the fillers they use in the synthetic T4 and T3 caused inflammatory problems for me. My numbers were at optimal, but the joint pain was, literally, crippling. When I switched to Naturethroid years ago, that horrifying crippling joint pain was gone. I did very well on that until all of the problems with nature throid and I switched to NP thyroid and I did very well on that until recently. Now I’m looking at getting a over-the-counter supplement because I don’t know how else to make this work.

            Janie, I hope the Lord blesses you in extraordinary ways for continuing to maintain this site and help all of us get through these challenging times! Thank you!

          • Janie Bowthorpe

            Your last comment is very kind, Rachel. Thank u. I could use any blessing I can get.

      • Anne

        what abot the other Ts and Calcitonin which helps prevent osteoperosis?

        Reply
        • Janie Bowthorpe

          Well, we can hope conversion to them will happen. And there are ways to buy just T2, I’ve noticed. But we have no experiences with it in order to guide.

          Reply
    • AP

      I have the same experience… lightly sweet and I had to dose down from the same amount I was taking of thailand thiroyd because the acella is stronger to me. I live very rural and most people are on synthetic. I wonder if my pharmacy just doesn’t go through the pills as fast. Who else is rural vs city and having good vs bad experiences?

      Reply
  188. Karen

    I just got off the phone with my pharmacist.she said this needs to be reported to the FDA. Because if accella does not recall this bad pills.This would push them to address this sooner.The more people who will report the quicker it will be resolved.we cannot sit back in fear about ndt being pulled and allow them to sell this crap and deny anything is changed.

    Reply
  189. Karen

    I just got off the phone with my pharmacist.she said this needs to be reported to the FDA. Because if accella does not recall this bad pills.This would push them to address this sooner.The more people who will report the quicker it will be resolved.we cannot sit back in fear about ndt being pulled and allow them to sell this crap and deny anything is changed.

    Reply
  190. Trudy

    Hi I wrote a few says ago asking if the same thing could be happening with the tablets from Thailand’, I take a product called Thiroyd which has always worked well till my batch last year which produced Tinitus in me but thought maybe it was a coincidence but have just started a new batch and the tinitus is even worse. Also very bad head, had to sleep sitting up last night but can’t be sure it’s from the tablets. Is anyone else having the same experience with these tablets. The armour tablets didn’t suit me at all. Don’t know what to do. I live in Ireland so don’t know where to turn. Many thanks, just reading your blogs makes me feel I am not going mad.

    Reply
    • Valency

      Trudy, after a new endo switched me to Armour in January, I developed severe tinnitus and with a throbbing/pulse in my head. I was finally able to switch back to NP and was doing much better until the last few weeks. They changed something and not the tinnitus is creeping back in, along with the throbbing head — especially bad in the morning when I wake up and take my initial dose. I never had tinnitus before taking Armour. Interesting note about the possible source being Thailand. I’m calling the manufacturer today (Acella) and I’ll see what they say.

      Reply
    • Trudy

      Thanks for confirming what I thought, I would say different tablets have the same base source. Have discovered I have a kidney infection and gastritis so am feeling a little better now on treatment and the tinnitus has eased a little.

      Reply
  191. Dawn

    So now I’m confused. The specked pills are bad with the horrible smell, and now there’s another new pill out there that’s white but has no smell and is just as bad? Thanks for clarification.

    Reply
    • Amy Lynn

      Dawn to answer your question, yes (at least, that was my experience.) The whiter pills that hardly smell (along with the speckled, smelly ones) are no good! Side effects/reactions galore. Again my experience, but maybe in time more people will chime in. Only good ones I’ve taken were the smooth, yellowish-colored ones with the normal ndt smell. I’ve been on NP for over a year now (about when the WP/naturethroid shortage started.)

      Reply
      • Ana

        I also had a very bad reaction to the white, odorless tablets. The symptoms I had (headache, inability to think clearly, difficulty focusing my eyes, stiff muscles, water retention, and a strange feeling in the back of my throat) were exactly what I experienced on synthetic t4/t3. I suspect that AvKARE (a repackager/distributor, not a manufacturer), working on behalf of Acella, subcontracted to a number of manufacturers to produce NP Thyroid. They probably went with the lowest bidders. My guess is that an unscrupulous manufacturer couldn’t obtain enough porcine thyroid powder and substituted synthetic t4 in some batches. I agree that getting the pills analyzed by an independent lab would be a good idea. I do wonder if that type of analysis would be able to determine whether the t4/t3 in the porcine pills was deactivated or not. By the way, there have been some recent problems with synthetic t4 drugs too. Patients have reported that Tirosint is no longer effective.

        Reply
        • Valency

          This is good intel — the pills I’m having the bad reaction to are white, hard, and have no odor at all. I’ve got a call scheduled with Acella this afternoon.

          Reply
  192. Karen

    Janiee she is right about the new pills.I got my new pills four days ago from accella they are light colored and no smell.after Taking them I also got the same symptoms and a few more.i know when I am having an allergic reaction and this was bad.i called and left a message again with David and told him something is definitely different in the pills.here is the lot#M327B193 exp date 1/2021.

    Reply
  193. Amy Lynn

    Important update, and maybe this discovery can help.

    I gave up on Acella ever sending me new pills and decided to go back to my pharmacy yesterday, and boy am I glad I did. Pharmacist on duty was super helpful. I showed her all the pills I had, she listened to all of my concerns (even showed her this post) and she then proceeded to open up 3 new, sealed bottles. She poured them out, and we both took a look. First bottle of 90’s were all smelly/speckled, no surprise there. 2nd bottle of 90’s were mixed; speckled/smelly in with the normal/yellowish smooth ndt-smelling pills. 3rd bottle were the 120’s (I take 2 different doses a day) and this one was the most shocking. 3 different looking pills inside! The yellow, normal ones, the speckled/bad ones, and different white, shiny, non-ndt smelling ones. Seriously they smelled like nothing! Not sure what this all means, but I don’t trust this company now. There’s just too much variation going on between pills in the same bottle. She said she could not in good faith sell the speckled ones, as she thought they smelled compromised/rancid, too. Going to try Armour and/or 2 synthetics until all this gets resolved.

    Reply
    • Janie Bowthorpe

      I want to copy and paste what you said was in one bottle, as that’s VERY strange and concerning:

      3 different looking pills inside! The yellow, normal ones, the speckled/bad ones, and different white, shiny, non-ndt smelling ones. Seriously they smelled like nothing!

      Reply
      • Amy Lynn

        Stop the thyroid madness yup, true story! I took the new white, virtually no smell 90mg NP this afternoon, and I’m not happy to have to report that I’m experiencing dizziness, dry mouth, vision problems (blurry/seeing spots & my pupils are so tiny even in low light it’s weird) flushing & redness on my cheeks/face. Done nothing else different and I take no other meds or substances. Not good!

        Reply
        • Karen

          Do you have the lot# because my replacement pills are light colored and no smell. I also had the same symptoms plus a few more.i knewni was having an allergic reaction.

          Reply
          • Amy Lynn

            Karen yes, I posted them in the lot numbers on Janie’s blog.

    • Karen

      Janie, New Lot #. M33OE193. Tastes horrible, symptoms returned like aching hands and feet fatigue, no patience.

      Walgreens, Monona WI

      Reply
  194. Val

    I cannot tell you how horrified I am to have found that I was correct, and there has been a change to my NP thyroid tablets. I thought I was nuts! The pills are noticeably harder — which no longer makes them ideal sublingually. Unfortunately, the horrible side affect of loud ringing in my ears that I experienced on Armour has now been duplicated with the NP. I’m guessing it is an additive that I am reacting to, something that hardens the tablet. Can we lobby them to change it back to what it was before? It was the only NDT that really worked for me. 🙁

    Reply
  195. Catherine

    Hi. It looks like some are reporting the pharmacy expiration date. I just wanted to comment that the lot and expiry number are on the original Acella bottle from the manufacturer that the pharmacy dispenses from. They usually come in 100 pill bottles. Note: the expiry number is not the one year expiration written by the pharmacy. You would need either the original 100 pill bottle or try to get the pharmacist to look it up. If they have a good computer system and are organized, then they should have that information.

    Reply
    • Hadassah

      I’m on the fence now with my NP refill .I’m due for a refill and my pharmacist told me that he has the 15mg NP it has no smell nor any specs and is all white as usual . That lot # was posted here that it’s not good. Is it possible that some even with the same lot # can be good ? Should I take the risk ????

      Reply
      • Janie Bowthorpe

        We are learning together. And somehow, it does appear that a lot number can be shared with either the former umchanged tablets and the changed tablet. So the best thing to do is go to the pharmacy and look for specks on the tablets. Specks seem to go with the changed tablets that have caused a lot of reported problems.

        P.S. As far as smell, all NDT smells. But the changed tablets, which seem to go along with a serious return of hypo and even worse symptoms (nausea, burning in stomach, to name a few) seems to have a quite pungent smell.

        Reply
  196. Jennifer

    I always get a sealed bottle of 100 NP Thyroid from Walgreens. On 4/26/19, I got a lot# M331A19-2 for 90MG Tablets, expiration date of 12/2020. At first I had some burning on my tongue when I took it sublingually. However, the pills looked and smelled normal. I was finally able to take them without problems. (I would like to note though that Acella now included a Serial#, GPIN#, and a bar code as well as their usual info of Lot# and Expiration Date on the bottle.) I asked Acella about this and they said they were updating their packaging for better tracking.

    I had my script refilled on 7/17/19. This time I got a bottle of 100 that expired on 10/2020 (2 months earlier than the bottle I had previously bought 3 months before). It also had the updated packaging including the Serial#, GPIN#, and bar code. I’m wondering why Acella suddenly updated their tracking abilities right before the horrible pills came out. I’m also wondering why my 12/2020 pills seemed okay and the older 10/2020 pills smell like cat urine and look differently. Does this mean they may have manufactured some decent pills since the bad 10/2020 batches?

    By the way, the best I can read it, it looks like my 10/2020 pills have a Lot# of M331B19-1.

    I complained to Acella 2 or 3 weeks ago. They said they’d get back to me concerning my case# but I haven’t heard anything. I haven’t called Walgreens. Maybe I should.

    Reply
  197. Christine

    Thank you for posting about this. I think that I have been affected. I was taking 60mg NP Thyroid with TSH 1.8 and low upper range FT3 and FT4 and feeling good for about 1 year. Labs and doctor visit in May 2019. Feeling good, continue the course. Refilled my NP Thyroid on 6/4/19 and after about a month I started to feel bad. Thought it was temporary and kept going. Emailed my doctor about 1 month later saying that I was feeling bad (headaches, fatigue, weakness, constipation, irregular periods, depressions, etc) for the past month and would like my thyroid checked. She agreed and my TSH was 4.38…highest I have ever been. I have since changed to Tirosint because I was suspecting that NP Thyroid may be raising my antibodies so this gave me the nudge to try something else. I kept thinking it was something that I was doing wrong but reading your post helped me to realize that perhaps it was out of my control. My pharmacy told me that they do not have the lot number for my batch 🙁

    Reply
  198. Sabrina Schön

    May be another Faktor X #7 ?
    The Producers have to treat the dessicated porcine Thyroids with a sort of desinfection/virucide as they found out, that the (new) sources are contaminated with whatever (african swine pest)??
    And what they say would be right “nothing obvius changed”.
    And it would explain every single reaction the patients report.

    Reply
    • Lisa

      But it shouldn’t change the size of the tablet.

      Reply
      • marny

        Hmmm…. if this were trye, an added chemical I would imagine eould affect clumping, and may have to add something to counteract it, making them dif shape? I wouldn’t put a pesticide past them.

        Reply
  199. Waveeylines

    Oh nooooo! So shocked to discover its now happening to NP!! What is going on? If theyve changed the fillers than thats me cooked as am sensitive. Am in the uk and our pharmacsots dont have the facilities to compound their own. I will not go back on levo and T3 it wasnt great and ndt was miles better. Cant believe its being suggested!!!
    Didnt armour change their lower strength tablets back to their old formula? Or was that a myth? I was fine on armour till they added cellulose in…..lol. Same with Erfa…..sigh….
    I dont think its a conspiracy as isnt Erfa made in Canada…….well spain now to be precise!!
    Now WP is back what is that like? I was on WP before they stopped production…

    Reply
  200. Carol

    I had previously posted that I got the NP 60’s that smelled like cat urine and were grayish colored. I went to a different pharmacy on Monday and was able to fill a 30 day rx with what appeared to be the good pills because they looked normal. They do have a strong taste and smell which has gotten stronger each day but not like cat urine and the texture is different. I am now getting random red itchy spots on my body and my nose, eyes and arms itch like crazy. My face is getting numb spots and my adrenals are surging which I haven’t had in years. This afternoon I took one of my good ones and had no itching, numbness or adrenal surges.

    Reply
  201. Thy Roid

    I’ve been trying to source a compounded version of NDT and finally found a pharmacy who can do this. The pharmacist told me that this porcine thyroid powder has been “unavailable for a long time and is only just now back on the market…”, which is interesting and I thought I would share this fact with the rest of you.

    What do you make of that? Can’t be the FDA thing with the Chinese supplier can it? This pharmacist told me they were getting their powder from Houston TX (doesn’t mean it’s not Chinese but possibly reduces the chances a bit).

    Reply
    • Thy Roid

      Follow up: I had a chance to discuss this issue in a later telephone call with the pharmacist. I was told that last year a shipment of NDT powder from China was initially approved or passed inspection. This powder made its way through several wholesalers in the US who likewise somehow approved this powder and sold it. This is the same powder that all commercial NDT pill makers use as well as some of the pharmacies that do compounding. Eventually the FDA discovered issues and cited the Chinese facility and that powder was withdrawn (as well as WP Thyroid tablets), which has already been discussed here.

      This pharmacist suspects that some of that powder made it into pills that were released to pharmacies and eventually sold to patients. Someone mentioned that the expiration period is typically two years and that the expiration dates noted in our work are largely 2020 dates. So pills manufactured in 2018 might just now be getting to us (or perhaps being dumped on us due to the shortage in new NDT powder?), and those pills might have contained the withdrawn powder.

      One possible explanation…

      Reply
      • Lynne

        I am concerned about the change as well—
        I am especially concerned about sources in China as there is not the same quality control there as in the US.

        Reply
        • Dee

          Another theory, from a medical friend, suggests that a great deal of the porcine powder was supplied by Puerto Rico.
          The hurricane a while back wiped that source out completely. So it is getting more difficult.

          Reply
  202. Lorraine S.

    yall trippin my NP thyroid been smellin like cat piss for a whole year now
    my most recent pickup actually smelled not terrible but i concur it does not seem to dissolve sublingually as easy

    Reply
  203. Jean N

    Has anyone actually received replacement pills from Acella? I was told they were sending a new bottle to my pharmacy, but nothing yet.

    Reply
    • Amy

      Jean N. Nope! And I was promised the same thing…new pills, either at the pharmacy or my door. Probably for a cost, saw a few say they got charged upon receipt. Even answered a bunch of questions from their “health department” (Billerica, Massachusetts phone #) Got a script for Armour, and if that doesn’t work adding in thyrovanz or switching to 2 synthetics, as I’m pretty much done dealing w/this company. They are denying anything has even changed, it’s absurd, nature/WP fiasco 2.0!

      Reply
  204. Judy Feyen

    My husband has been taking Acella NP thyroid 120 mg for about 9 month now and has had better #s then when he was on Naturethroid. He initially did well on Naturethroid until they changed, then his TSH shot up to 8. He just refilled his NP script and they are larger and have specks, so I assume they are the new batch. Our pharmacy fills their own bottles and I dont see a batch #. We are going on a 1 month vacation so I don’t know what to do at this point. He has kidney issues as well as high BP. When his thyroid meds are working his kidney function is better and so is his BP ( he does take BP meds too). Have those who have been chewing them found them to be more effective. I guess I could call his Dr and relay my concern, but the Dr. seem to be the last ones to realize there a problem. Plus I wouldn’t know which NDT to ask them to switch him to. Has anyone had luck with Armour lately?

    Reply
    • Cincolo

      I’ve been chewing mine for the last 6-7 days and am feeling much better.

      Reply
    • Jenny

      I have been on Armour for the last 2 months and am doing really poorly- symptoms all over the place: Hypo and hyper… can’t get up in the morning, weird rashes on hands and scalp. Depressed and anxious. Heart tightness… constipation and then the runs…each pill seems different… I am probably going to have to go on synthetic…I don’t know of any other choices? Was on the natural pig thyroid for 9 years…. Armour, Naturethyroid, Np and now Armour again – nothing seems to work… I don’t know what choices I have left?

      Reply
  205. OM

    Lots more reports about problems with NP on Drugs.com. Seems the only thing all of the NDT thyroid hormone drugs made in USA have in common is the USP porcine thyroid. Also noted that some compounding pharmacies can no longer get the USP thyroid hormone for compounding. Some had used thyroid from China prior to this. Wish we could have the USP thyroid hormone that is used in all of the NDT drugs analyzed!

    Reply
    • Janie Bowthorpe

      It’s being explored…

      Reply
    • Janie Bowthorpe

      The sad part of what’s on drugs.com is that it’s loaded with people who were underdosed or had an iron or adrenal problem…and don’t get that it’s NOT the NDT that’s the problem..it’s what it’s revealing from any of the latter.

      But now, we have a truly lousy NDT with “NP Thyroid” by Acella–it’s now changed and sucks, all while Acella says they changed nothing and only focus on the size, smell, etc. So when you read what someone says, you also have to note if they mention the horrid smell, the awful taste, the large size tablet, specks. Those tablets represent a change to what’s inside—a now VERY bad product causing a massive return of hypothyroidism, as well as nausea, repulsion, burning when they swallow, etc.

      Reply
      • Hadassah

        Janie I would love to know which NDT do you recommend now after the NP fiasco ? Are you thinking about synthetic T3 also ? If yes which one would you recommend ?
        It’s crying shame what is being done with our thyroid meds that worked so well for us .

        Reply
        • Janie Bowthorpe

          I stopped recommending them. Just not seeing enough strong and consistent positive results since every single one of them has changed and not giving the quality results they used to. It’s irritating. But there are some individuals who feel they are doing well on compounded ndt or Armour. Hardly any doing well on the others. So I just leave it up to you. Also, being OPTIMAL on T4 and T3 could be good, too.

          Reply
          • Hadassah

            Thank you Janie . I guess going with synthetic T3 and T4 is the only option we have now I guess this is what they wanted us to do from get go . What a shame .

          • Karen SFerguson

            I understand why you don’t recommend them, but can you tell us which thyroid med you take? If I have to switch to another NDT (I’ve tried Armour, Naturetroid, straight T3, WP Thyroid and now on NP Thyroid) it would be nice to know what meds work for others.

          • Janie Bowthorpe

            I’m still on the former-working NP Thyroid.

  206. Laurie

    I talked to my pharmacy today about NP Thyroid. The person I talked to said she was not aware of any problems with NP and that there have not been any recalls. She seemed surprised. I let her know that I had hypothyroid symptoms and that the pill did not seem like what I had been taking. The smell and taste were different and it tasted toxic. My lot number for the new batch of 90 that I have is M327B19-1

    Reply
  207. Suzette

    Hello,
    I have been in NPThyroid for several years but just picked up a new 3 month script only to find they taste like iodine has been added… a LOT of it. I too, wrote Acella only to be told they haven’t changed their formula. I haven’t yet gotten the Lot# for you but I will. However, I wanted to mention something that may help explain why these companies are changing their formulas. Actually, there are two reasons that I believe this is happening. You may think I’m a conspiracy nut when you read the second one. The first reason is to make the tablets longer acting. Many of us began having trouble with Armour not working. Then we found out they changed or added a filler: some form of cellulose. Cellulose is a fiber and is being used to slow down the absorption of the thyroid hormones in the medication apparently to make it more like a time-release product. This works for some people, but for others its a disaster. I guess some people cannot break the cellulose down enough (I’m one of those people) to get the thyroid so its like taking your thyroid med with food. The other reason is the conspiracy one. I believe that all these manufacturers aren’t just waking up one day and deciding to fix something that’s not broken thereby losing revenue because so many people stop buying their drug. It doesn’t make sense does it? So, what would make them all do this? Well, we know the FDA and many medical establishment people do not like NDT. They SAY its because of one thing or another but they cannot prove synthetics don’t also have some of these issues, if they even exist. So then why don’t they like NDT? Simply because its a natural product. Look at what they have been doing to the natural supplement industry for the last 10-20 years. They do not want us taking naturals. So, do I believe they are “leaning” on manufacturers of NDT? You bet I do. They know if they just suddenly pull them off the market the uproar would be huge. But if people decided themselves that NDT was no good, or didn’t work for one reason or another, they would be forced to go to synthetics. As an aside, Hillary Clinton takes NDT, I believe its Armour. Wonder if she’s having problems.
    Anyway, that’s my two cents. I am very concerned about the iodine taste/smell because women who are past menopause should be careful taking iron as it can raise their risk of heart attacks. At least that’s what I was told years ago. Maybe that has changed but since I’m past that age and have no thyroid, I am wondering what to do. I have only been on this new bottle for about a week so I don’t know if I will have any problems but the fact that it tastes so strongly like iodone has me very concerned.

    Reply
  208. Suzy

    My labs were bad with my older batch of NP. The new prescription is different but I’ve been doing better. Maybe just a bad batch.

    Reply
  209. Emily

    In response to your e-mail:
    1. How do you know that you are reporting on the CHANGED NP Thyroid tablets?
    My new tablets are thicker, speckled and smell like ammonia (cat urine)
    2. Comment with the lot number for the bottle of what are clearly CHANGED NP Thyroid tablets
    Lot #M328S19-1
    3. Comment with the expiration date for what are clearly CHANGED NP Thyroid Tablets.
    Bottle says EXP 07/30/19, but I think that’s a typo as it was filled on 07/30/19
    4. State the city, state, country, and name of store/website where you got the changed tablet
    Kailua-Kona, HI, USA, Walmart

    Reply
  210. Melanie and David R Schrand

    Hi there, I have been taking np thyroid for a couple of months and although I am still not feeling well, something is wrong because all my symptoms are worse and I was at least stable before. I don’t know if it is the Np thyroid or the fact that I lowered it and added in T3 to lower my RT3. I don’t see a batch number only rx numbers, but they were filled in July 2019. Do you think it will be better to go on the synthetics then?

    Reply
  211. ELISSA JUNG (CUPCAKE)

    THIS IS NOT A COMMENT BUT A MEDICAL TRAVELOGUE. IN THE SPRING OF 2015 THERE WAS A NOTICE ON DRUGS.COM OF A ‘LABEL CHANGE’ FOR SYNTHROID AND ARMOUR. ‘LABEL CHANGES’ ARE NOT EXPLAINED NOR IS THERE ANY EXPLANATION GIVEN.I RENEWED MY SYNTHROID AND WITHIN 3 DAYS MY NORMAL BLOOD PRESSURE OF 120ISH SHOT TO 210 OVER 110. MY HEART WAS RACING, I HAD DIFFICULTY STANDING AND GENERALLY FELT HALF DEAD. STOPPED THE MED, WAITED TWO WEEKS, PRESSURE CAME DOWN, STARTED MEDS AGAIN…SAME REACTION AND STOP MEDS. IT TOOK ME A GOOD YEAR TO FIND THE CULPIRT(S). THERE WERE TWO ADDITIONS ADDED TO THE INATE LIST..ACACIA FOR PILL WHITNESS AND LACTOS FOR SWEETENER. ACACIS IS A SHRUB, IN THE SAME FAMILY AS ‘RAGWEED’. LACTOS COMES FROM DAIRY. I AM VERY ALLERGIC TO RAGWEED AND DAIRY…THEREFORE THE SEVEAR REACTION. WHAT ELSE IN THIS UNLISTED INATE ADDITIONS COULD EFFECT MY THYROID SISTERS? WAS A SUPPLIER CHANGED? WAS THE CLEANING OF THE PILL MAKING MACHINE NOT RINSED OFF? WAS THE PACKING MATERIAL INFERIOR? WAS THE NATURAL THYROID HORMONE TAKEN FROM A SUMMER ANIMAL? OR A WINTER ANIMAL. ROBUST/STRONGER IN SUMMER,WEAKER IN WINTER? MY SYSTEM WAS NOW TOTALY OUT OF WACK, PRESSURE WAS ALL OVER, FROM HI TO LOW WITHIN 2 HRS. STILL FELT LIKE DEATH WARMED OVER. WORKED WITH DAVID AT ACILIA, WHO WAS VERY HELPFUL BUT I COULDN’T EVEN HANDLE HIS LOWEST DOSE MED. HEART WOULD POUND, I WOULD GET THE SHAKES, COLD BEYOND BELIEF, AND FATIGUED AS LAST WEEKS OVER COOKED NOODLE. IT WAS AT THIS JUNCTURE I DECIDED TO BECOME MY OWN DR. I USED MYSELF AS MY Petri dish AND BEGAN TO RESEARCH WITH WITH A VENGEANCE. RATHER THAN ACCEPT THE INTERNETS ARTICLES I BEGAN TO READ THE PHASE ONE/TWO TESTS REFERRED TO AT THE BOTTOM OF THE PAGE. MANY TIMES THEY WOULD ADD ODD THINGS THEY SAW, NOT VETTED. HERE ARE SOME… HYPO CLIENTS SEEM TO HAVE MORE ALLERGIES THAN OTHERS. HYPO CLIENTS TEND TO GO GREY YOUNGER AND HAVE A HIGHER SEX DRIVE.(I CAN VETT THIS ONE). A SMALL SEGMENT OF CLIENTS WERE UNABLE TO CONVERT T4 TO T3 AND ADDING T3 SEEMED TO HELP. IT HAD ME BOUNCING OFF THE WALLS, IN DESPERATION I STOPPED ALL MEDS. SOME HOW I BEGAN TO FEEL BETTER BUT WAS STILL SUFFERING WITH THE AFTERNOON SLUMP. TO MAKE SURE I WAS HYDRATED I WOULD HAVE 5 OZ OF COLD WATER, A GOOD SPLASH OF LEMON JUICE AND A SHAKER OF SEA SALT. SOMEHOW THIS WAS A BIG BOOSTER TO MY FATIGUE, BUT I DIDN’T KNOW WHY. IT WAS CHEAP, HAD NO REACTIONS AND WAS PLEASANT TO TAKE SO I CONTINUED, BUT STILL WONDERING HOW COME IT WORKED. ONE DAY I WAS READING RECIPES AND THERE WAS A FOOT NOTE ABOUT SEA SALT THAT IT HAD THE TENDENCY TO ‘OPEN UP CELL WALLS’ TO ALLOW NUTRIENTS TO PASS THRU. THAT’S WHY MY CITRUS/SEA SALT DRINK WORKED. FLUSHED WITH SUCESS I DECIDED TO ATTACK MY ERRATIC BLOOD PRESSURE. SINCE I AM ALLERGIC TO SO MANY THINGS THAT IS WERE I STARTED. I FINIALLY GOT DOWN TO MY SUPPLEMENTS. I STOPPED ALL AND BINGO MY PRESSURE WENT BACK TO THE OLD 120ISH. IT WASEN’T THE VIT. IT WAS THE “PILL”!!! NOT THE CAPSULE. BESIDES THE WELL KNOWN ALLERGIES…WHEAT/GLUTON, DAIRY, EGGS,RAGWEED, PEANUTS LOOK TO THE TYPE OF CONTAINER YOUR MEDS COME IN. THE INATE FILLERS IN PILLS, TABLET COULD BE DOING YOU HARM…CHECK IT OUT.
    HAPPY RESEARCHING

    Reply
    • Niko

      Have you ever been checked for Mast Cell Activation Disorder?

      Reply
      • Jeanne

        Niko, most docs have never heard of MCAS. Both my daughter and my mom have it, and I was the one to diagnose it! Not a doc, but a 25 year RN Clinical Nutritionist.

        For any one wanting to know more, there is an excellent book by the MD who put all the puzzle pieces together and coined the term “Mast cell activation syndrome”.
        “Never Bet Against Occam” by Dr. Lawrence B. Afrin MD. Available on Amazon.

        Reply
  212. Debbie Kimbrell

    Has anybody considered the possibility that the manufacturers are telling the truth, and didn’t change anything? Perhaps the problem is that the composition of the source of the active ingredient (or maybe even an inactive ingredient?) has changed? I ask this because so many NDTs are problems now.

    Taking both NP Thyroid 120 and NP 30, my last refills were 4/26/2019. A month later, I was very, very ill with many symptoms I had never had before. Thinking I was overactive, I began decreasing, with no improvement, until I was only on NP 30. After seeing the picture of the changed NP tablets, I realized my NP 120 tablets were not changed – but the NP 30, the only tablets I was currently taking, were speckled, which explained why my symptoms had not disappeared. And now I had a TSH of 13 (where for many years it had been 0.1) !

    I am no longer taking any NP Thyroid.

    Reply
  213. Jim

    Just noticed this update from Acella ( https://stopthethyroidmadness.com/2019/08/22/uh-oh-np-thyroid/#respond ):
    NP Thyroid® Product Update
    8/30/2019 Product Update : Providing updates and feedback about your questions related to NP Thyroid® is important. Our customer service has reported an increase in calls and emails related to the odor or taste of NP Thyroid®. We are also aware that there are some comments about this on social media sites. At Acella Pharmaceuticals, our priority has always been, and will continue to be, to provide our customers with quality, consistent and cost-effective products. Our API is sourced from FDA inspected facilities, and we manufacture NP Thyroid® in the USA to USP standards following cGMP practices. As a result of the upheaval in the desiccated thyroid market in the past few years, we have had to upgrade and expand our production capabilities to keep up with increasing demand for NP Thyroid®. We do not use any API material sourced directly or indirectly from China or India. Rest assured that our formulation, specifications and exacting quality standards for NP Thyroid® have remained consistent. NP Thyroid® is a product derived from natural sources, and you may notice the odor, taste and shade of our tablets may vary slightly from batch to batch. It is important to note, however, that we test each batch of NP Thyroid® to ensure that the finished product is within the USP (United States Pharmacopeia) specifications for T4 and T3. We have found no indication that slight variations in odor, color or size of the tablets affect their content, quality or consistency.

    If you have any questions or concerns with NP Thyroid®, please contact us at info@acellapharma.com or (800) 541-4802. Moreover, if you experience a change in your thyroid related symptoms at any time, you should contact your licensed healthcare provider.

    Reply
    • Cincolo

      Funny how every time they say they need to update their production facility, the product seems to get screwed.

      Reply
  214. Ellen

    PU. I stopped taking NP Thyroid after my symptoms got the best of me. Aches, dry eyes, fatigue. When I called Acella, they said, “batches can be different but the standards are the same.” I told them to raise the bar. Their new “batch” smells horrible, tastes even worse, has a different size and look, and makes me feel worse than ever. How can that be acceptable?

    Reply
  215. sam

    sorry am too tired to read it all but i recommend thyrogold . its from organic pasture raised cows isntead of factory farmed GMO fed poor pigs

    . it works too.

    also eating all orgnaic [ grown in real soil [ not hydroponic, hydropinc does not ahve the nutrients that soil organic does plus does nohting for the environmnet ] relaly helps for good health and curing digestion problems .

    hope this helps wiht people having problems with the pharmaceuticals.

    am s till tired but at least feel much better than wiht the horrible synthroid

    Reply
  216. Cincolo

    I’ve been chewing my tablets the past 5 days and am actually feeling better. Contrary to what others are saying, my tablets are extremely sweet (with the porcine taste only if it’s stuck in my teeth). I drink extra water afterwards though to wash the taste out of my mouth. Mine don’t taste anything like they smell. I’m actually surprised they are so sweet. Naturethroid and Armour were never that sweet when I chewed them (after they were modified). I’m taking 60 mg and 30 mg tablets daily. Anyone else noticing they are doing better after chewing them?

    Reply
  217. Wendy Benton

    I had commented a few days back about my problems with the new Acella. I callled the company and they called me back and were very nice, asked a whole lot of questions and are going to get a sample of my pills. After I got off the phone with Steve, I poured out my pills and compared them to an old one. Could not really see much but then I took a closer look and noticed that only some of the new pills were a shade darker colored. I put a lighter one under my tongue and it was fine then a darker one and the taste was horrible and I spit it out. I have a call back to him to let him know.

    Reply
  218. Ann Rankin

    Hi Janie, To be on the safe side I personally will not consume any of the new tablets that are making people sick. It’s one thing to have the pills cause return of hypo symptoms. It’s another thing entirely when people are saying it is making them gag, become nauseated, have stomach pains, and burning tongue plus more! Why are some continuing to take a chance with their health and safety by taking them?

    Reply
  219. Laura Beckwith

    Not sure what to do, my ND changed my dosage from 60mg of NP Thyroid to 30mg of NP, 5mcg of liothyronine, the 30mg is the one with the change. I have been taking since the Labor day weekend, besides the already known changes, I chew my NP thyroid, and it’s foul tasting, and I feel like gagging. I think my stomach slightly feels a bit different after taking it as well. The taste/aftertaste stays in my mouth so pewtred.

    Reply