T4-only meds like Synthroid do NOT work, exclaim many patients!
(Important note: STTM is an information-only site based on what many patients have reported or learned in their treatment. Please work with your doctor. This is not meant to replace that relationship or guidance, and you agree to that by reading this website. See the Disclaimer.)
Why does this page state that for too many thyroid patients, T4-only medications like Synthroid or Levo didn’t work well enough?
First know that it’s not based on strong opinion.
Instead, the information on Stop the Thyroid Madness is based on the reported experiences of a large body of patients worldwide in groups and over the years while on their T4-only meds (Synthroid, Levoxyl, Levothyroxine, Unithroid, Eltroxin, Levaxin, Norton, Eutrosig, Oroxine, Tirosint, for example).
i.e. apparently, T4-only was NOT doing the job as a sole treatment for all too many…unless you think that an elevator that goes up to the 5th-floor-only on a 50-story building is “doing the job”.
Granted, we do hear from those who feel they are doing great on T4-only! And we applaud that! But on the other side of the coin, there are also many who, though they feel they are doing well, report symptoms which creep up over time. Or, they have symptoms which they never thought was connected! It appears by so many reported experiences that the body is not meant to live for only one of five thyroid hormones for all too many.
**You can read a lot more interesting information about T4-only in Chapter 1 of the revised STTM book.
But “we’re all different” right?? What doesn’t work for one may work for another, right?
If ten people were playing in a street, and seven were run over, would you still approve of playing in the street because three didn’t get run over at that moment in time…in the name of “We’re all different” or “Whatever works” or “To each his own”?
In summary, on only one of five thyroid hormones, some never feel better; some do better but still have problems like Fibromyalgia, hair loss, depression, anxiety, low iron or b12, rising cholesterol or blood pressure, etc; some do well for years (or they thought, not realizing what was actually happening); some never needed treatment in the first place since pure and simple chronic stress can raise the TSH..aka secondary hypothyroidism that would go away in the first place once stress was relieved.
Why doesn’t T4-only work well for so many, based on their reports?
Please consider that a healthy thyroid makes five hormones: T4, T3, T2, T1 and calcitonin. T4, also called thyroxine, is simply a storage hormone meant to convert to T3, the active hormone. But a healthy thyroid doesn’t make you totally dependent on conversion alone, giving you direct T3 plus the other hormones above. So in other words, being on a T4-only med means you are missing out on direct T3 as well as the compliment of all five hormones.
Summary: all the following can negatively affect the conversion of T4 to T3: getting older, chronic stress, taking calcium/iron/estrogen or high fiber at the same time, excess uncooked goitrogens daily, poor nutrient absorption, chronic fasting, chemotherapy or radiation, excessive intense exercise, chronic inflammation, low testosterone, certain medications, liver stress, low iron, genetics and lyme disease.
And what do too many uninformed doctors do for the symptoms someone on T4-only might have?
What our doctors tend to do is what we call “band-aid treatments.”i.e…..
Summary: it’s just too common for doctors to bandaid continued symptoms of hypothyroidism with antidepressants, anti-anxiety meds, statins, blood pressure meds, or pain meds…or to exclaim “Exercise more, eat less, go see a therapist, your TSH is normal”.
But what about Tirosint, a newer version of T4-only?
Tirosint is a liquid version of T4 which patients have reported doing better on than Synthroid or Levo. But the clear answer is: T4-only is T4-only is T4-only. We again saw that even on Tirosint, patients have reported problems by Tirosint forcing your body to live for conversion to T3 alone. Feeling better apparently doesn’t equal getting rid of all symptoms of hypo, or avoiding the problems that too many encounter down the line from forcing their bodies to get T3 from conversion only.
So what’s a better alternative to being on T4-only?
Patients are returning to a medication that was successful from the late 1800’s onward: natural desiccated thyroid hormones (NDT). Most are made from pig glands, meet the stringent guidelines of the US Pharmacopoeia, and give patients exactly what their own thyroids give them—T4, T3, T2, T1 and calcitonin. It’s powerful and it works.
Additionally, when on NDT, patients are not dosing by the lousy TSH. Instead, they raise their desiccated thyroid (NDT) according to criteria mentioned on the NDT page on STTM, straight from the experiences of patients. Even adding synthetic T3 to your synthetic T4 is miles better than being on simply T4, report patients.
**You can read a LOT more interesting information found nowhere else about natural desiccated thyroid in Chapter 2 of the revised STTM book.
I once tried Natural Desiccated Thyroid and it gave me problems! Why?
In other words, read this: //www.stopthethyroidmadness.com/ndt-doesnt-work-for-me to learn about the problem of too high or too low cortisol or inadequate levels of iron. This is why patients have found it to be so important to test their adrenals via saliva before being on, or raising NDT…as well as testing all four iron labs (i.e NOT just ferritin). Equally common as to why patients think NDT failed them? NOT RAISING HIGH ENOUGH (in the presence of good iron or cortisol(.
It’s important to test and correct iron and cortisol before raising!
What’s the BOTTOM LINE?
Years and decades of reported patient experiences and wisdom tell us that the risk for problems is far too high with T4-only…sooner…or later, for too many. It’s not a pretty picture. So patients feel strongly: Why risk it? Work with your doctor on this.
Want to learn more? Here you go…Listen to an audio version of some of this page.
- Watch Janie talk about T4-only vs NDT
- Learn more about natural desiccated thyroid,
- Here’s a great summary of what patients have learned about all of this.
- See the different brands of desiccated thyroid
- Here’s the labwork you need and places to get it on your own to share with your doctor
- Here’s how to find a good doctor. And remember: YOU need to face your doctor informed and assertive. Use the revised STTM book to take with you.