Inflammation is a healthy and positive response of your immune system to counter the infectious problem of a virus, bacteria or fungal excess. It can also be activated by an irritant (picture a splinter in your finger) or damage to your cells from an injury.

But in thyroid patients, whether with 1) insidious Hashimoto’s disease, or 2) non-autoimmune hypothyroidism of any cause, the inflammation response can become chronic and problematic! And while many thyroid patients may be clear they have inflammation, others may have it with no clue! The latter is common.

The following article was written by thyroid patient Mary, plus more contributions by Janie A. Bowthorpe, M.Ed., to help you become informed and pro-active about this potential problem.


It’s all too common for thyroid patients to find themselves with high levels of inflammation as discovered by certain lab work, such as a high ferritin (iron goes into storage when inflammation is present) or a positively high C-Reactive Protein (CRP).  High ferritin is far more common!!

Why is chronic inflammation a concern?

  • Chronic Inflammation can spread and affect far more than a localized area. And sometimes that spread can have serious results.
  • Chronic inflammation can also result in dampening of your HPA axis (meaning you won’t signal your adrenals well to produce cortisol).
  • Chronic inflammation can result in higher blood pressure, allergies, joint pain, heart problems, harmful swelling, bone loss, lowering of iron and so much more that is negative to your health and well-being.
  • Chronic inflammation can also raises the protein hepcidin, which inhibits iron circulation, and the latter means iron will go into storage, plus your reverse T3 goes up, making you more hypothyroid.
  • Hashimoto’s-caused inflammation from the attack on the thyroid raises the risk of awakening other autoimmune diseases.

What lab work do I need if I haven’t proved inflammation yet?

Patients first start with the ferritin lab–that can go higher even in the presence of small inflammation, but will go even higher the longer and stronger the inflammation is going on  (usually ~90’s or above for women; ~120’s or high for men), i.e. your body will push iron into storage, pushing it higher and higher in response to inflammation. Other inflammation labs are CRP (C-Reactive Protein) and ESR and can be ordered from My Med Lab without a prescription. CRP is also helpful with infection-caused or antibody-caused inflammation, and ESR is helpful to show chronic inflammation. But most find their inflammation with ferritin. If we don’t but suspect inflammation, then we get CRP and ESR.

Action Plan for Inflammation


Patients have learned that a huge step in lowering that inflammation (which can be hypothyroid-caused) is being on an optimal thyroid treatment – that is, natural desiccated thyroid, or even adding T3 to that T4 in an optimal amount, NOT T4-only medications like Synthroid or Levothyroxine. Read Chapters 1and 2 in the **new updated revision** STTM book.


It’s very important in lowering inflammation to get those antibodies down, avoid environmental triggers, moderate or lower stress, and be careful what you’re eating. Get the book Hashimoto’s: Taming the Beast for important information on how to get those antibodies DOWN based on patient experiences, and treating inflammation.


Don’t guess! Do a 24 hour adrenal saliva test! If saliva reveals a problem, patients then treat any adrenal issues based on those results. Low cortisol can contribute to inflammation, since the right amount of cortisol is naturally anti-inflammatory. There’s an adrenal chapter for those with Hashimoto’s in the book Hashimoto’s: Taming the Beast.  It’s a companion book to the **new** updated revision Stop the Thyroid Madness: A Patient Revolution Against Decades of Inferior Thyroid Treatment

Important note: STTM is an information-only site based on what many patients worldwide have reported in their treatment and wisdom over the years. This is not to be taken as personal medical advice, nor to replace a relationship with your doctor. By reading this information-only website, you take full responsibility for what you choose to do with this website's information or outcomes. See the Disclaimer and Terms of Use.