bodiesNormally, inflammation is a naturally healthy and positive response of your immune system to counter the infectious problem of a virus, bacteria or fungal excess. It can also be activated by an irritant (picture a splinter in your finger) or damage to your cells from an injury.

But in thyroid patients, the inflammation response can become chronic and problematic! And while many thyroid patients may be clear they have inflammation, others may have it with no clue! The latter is common.

The following article was written by Thyroid Patient Mary, plus more contributions by Janie Bowthorpe, to help you become informed and pro-active about this potential problem.


It’s all too common for thyroid patients to find themselves with high levels of inflammation as discovered by certain lab work, such as a high ferritin result with inadequate iron or a positively high C-Reactive Protein (CRP). In fact, one may be low, while the other high!

Why is chronic inflammation a concern?

Chronic Inflammation can spread and affect far more than a localized area. And sometimes that spread can have serious results. Chronic inflammation can also result in dampening of your HPA axis (meaning you won’t signal your adrenals well to produce cortisol). Chronic inflammation can result in higher blood pressure, allergies, autoimmune issues, joint pain, heart problems, harmful swelling, bone loss, lowering of iron and so much more that is negative to your health and well-being. Chronic inflammation can also raise your reverse T3, making you more hypothyroid.

What labwork do I need if I haven’t proved inflammation yet?

Patients first start with the ferritin lab–that can go high in the presence of inflammation for many (though not all), i.e. your body will push iron into storage, pushing it higher and higher in response to inflammation. Other inflammation labs are CRP (C-Reactive Protein) and ESR and can be ordered from My Med Lab without a prescription. CRP may not show whether the inflammation is coming from your gut or joints, but ESR can, say some medical professionals. In many thyroid patients, the big clue is a high ferritin for most, but not all…thus all three labs.

Action Plan for Inflammation

      1. TREAT YOUR HYPOTHYROIDISM or HASHIMOTO’S PROPERLY Patients have learned that a huge step in lowering that inflammation is being on an optimal thyroid treatment – that is, natural desiccated thyroid, or even adding T3 to that T4 in an optimal amount, NOT T4-only medications like Synthroid or Levothyroxine. (Read the Things We Have Learned page on STTM, or even more details in Chapter 3 in the new Revised STTM book).
      2. DISCOVER AND TREAT POTENTIAL ADRENAL ISSUES Don’t guess! Do a 24 hour adrenal saliva test! If saliva reveals a problem, patients then treat any adrenal issues based on those results. Low cortisol can contribute to inflammation, since cortisol is naturally anti-inflammatory. (Read the Adrenal Wisdom page on STTM, or more details in Chapter 6 in the new Revised STTM book.)
      3. TRY TO IDENTIFY THE ROOT CAUSE OF YOUR INFLAMMATION. Here are several possible reasons…(Janie has added to these, too)
        • Chronic life stress
        • Non-alcoholic Fatty Liver Disease (liver labs like ALT would reveal this)
        • Autoimmune triggers like foods you eat, stress, infections
        • Bacterial imbalance or overgrowth
        • Bacterial infection, such as H. pylori (if you have low iron, check into this!)
        • Lyme disease
        • “Hidden” food sensitivities or allergies
        • Gluten intolerance or Celiac
        • Thyroiditis and the attack on your thyroid like Hashimoto’s
        • Yeast/Fungal overgrowth, such as Candida
        • Mold exposure (can cause Chronic Inflammatory Response Syndrome aka CIRS)
        • Parasites
        • Underlying viral infection
        • Low cortisol (as confirmed by saliva testing, NOT blood)
        • High cortisol
        • Mixed high and low cortisol
        • Continued hypothyroidism, especially those who use the inadequate T4-only or dose by the TSH.
        • Heavy Metal Toxicity (Hair testing from Direct Labs (3rd one down on list) can help detect what you are high in)
        • Inflammatory bowel diseases
        • Hidden or exposed tooth infection (this happened to Janie Bowthorpe under a root canal)
        • Cancer
        • MTHFR mutation or other methylation issues (which causes those high levels of certain metals)
        • Excessive consumption of high oxalate foods


      1. LOOK TO YOUR GUT IF NOTHING ABOVE FITS A healthy human body is estimated to contain ten healthy bacteria for every 1 cell! The presence of beneficial bacteria is essential to maintain health, particularly of the GI tract, and to prevent pathogenic bacteria from taking up residence. Fermented foods and drinks can help populate and maintain the presence of these beneficial bacteria. Good probiotic supplements can help as well.
        • Increase healthy fats and cut bad fats. Consume fats that are rich in omega-3, not omega 6 or 9, including meats from healthy animal sources (that is, from grass-fed, not feed lot meats). And though coconut oil and extra virgin olive oil are also good fats, they have only minimal omega-3 by the way. Avoid pro-inflammatory fats from oils that are rich in omega-6 such as safflower, sunflower, corn, peanut and soy.
        • Address hidden food allergies or intolerance’s. For some people, the gluten-containing grains wheat, barley and rye or even any grains cause an autoimmune response, leading to inflammation. For others, dairy, eggs, soy, nuts, nightshades and even meats can be problematic and will cause inflammation. EnteroLabs offers sensitive stool testing for food allergens, which many patients report being the most accurate. Cyrex laboratories also specializes in gluten sensitivity blood tests. However, the sure-fire way to know is to conduct a strict elimination diet, such as this one.
        • Eliminate refined sugars from your diet, since they increase insulin resistance, weight gain, and inflammation, and can contribute to candida yeast overgrowth. Natural sugars, such as fresh fruit, raw honey, and maple syrup may be beneficial. Be cautious of over-consuming high oxalate foods since they can trigger pain and inflammation.
        • MORE HERE:


    1. CONSIDER TAKING THE ANTIOXIDANT SUPPLEMENT LIKE ASTAXANTHIN. While eating wild Pacific salmon is one way of obtaining astaxanthin, it would take eating it daily to get the amount we could be getting from a supplement. Triple Strength Astaxanthin by Healthy Origins brand might be a good choice because it is marine microalgae-based; they do not use chemicals in their processing; and the serving size of 12 mg is a solid dose. But there are other good brands as well. (Mercola recommends 12 – 20 mg.)
    2. OTHER ANTI-INFLAMMATORY SUPPLEMENTS Find the supplements that work best for you, and sometimes a combination is key…for example, adding turmeric or curcumin with Astaxanthin plus Krill Oil.**Please research in case you have an allergy to something below! And always work with your doctor!

      • Selenium (patients often test first)
      • Bioflavanoids
      • Serrapeptase
      • Glucosamine and chondroitin
      • Lactoferritin (found in breast milk, supplements, and even colostrum supplements)
      • Pau D’Arco tea
      • Ginger 
      • Turmeric (though it’s high in oxalates, so if you have an oxalate issue the way Janie often does, you can go for straight Curcumin, which is within turmeric and gives the anti-inflammatory properties.) This is Janie Bowthorpe’s favorite way to lower inflammation, such as six caps in the morning and 5 in the evening. 
      • Guggul (note that this can also increase thyroid hormone production)
      • Cat’s Claw – treats inflammation (by suppressing TNF-alpha synthesis–which is needed in the inflammation process)
      • Boswellia (Frankincense)
      • Fish oil
      • Holy Basil, which is anti-inflammatory due to its high vitamin K content, is also an anti-histamine and it can help with high blood sugar issues. **Be careful, because it can lower cortisol if taken too long or in high amounts.
      • Berberine can help lower blood sugars and clear inflammation.
      • Bromelain
      • Cilantro, including tinctures such as this one or this one, can help detox mercury, arsenic, and lead. Some suggest taking it in smaller amounts and with a binding agent, such as chlorella.
      • Chlorella
      • Aloe Vera
      • Slippery Elm
      • Pink Rock Rose (Cistus Incanus) has anti-inflammatory, antioxidant, antibacterial, and anti-viral properties.
      • Rosehips
      • Pomegranate
      • Neem
      • Read about more anti-inflammatory herbs here
      • There is some evidence that Resveratrol supplements may lower inflammation.
  1. EXERCISE CAN DRAMATICALLY LOWER INFLAMMATION And if you have low cortisol, don’t push yourself; gentle movement can help, along with being in tune to your body’s limits.
  2. OPTIMIZE VITAMIN D LEVELS, which inhibits inflammation naturally and is a key component for a healthy-functioning immune system.
  3. DE-STRESS (See Number 2 about treating adrenals.) Take time to be quiet. Meditate, pray, contemplate. Do deep-breathing exercises periodically throughout the day. Get good sleep.
  4. If you are taking higher amounts of iron supplements in trying to raise low iron, we’ve found we have to lower them, since all inflammation does is push more and more iron into storage, floating around our bodies.

Also, note that pre-existing inflammation can exacerbate methylfolate supplementation in those with MTHFR gene mutation.

An Important Note: Low Iron with high ferritin = Inflammation

Sometimes this condition of low iron with high ferritin has a fancy-dancy, scare-mongering name called Anemia of Chronic Disease (ACD) or Iron Deficiency Anemia (IDA). But honestly, that high ferritin with low iron just represents inflammation, as your body is thrusting iron into storage in the presence of inflammation, so as not to feed the inflammation. Still very important to lower the inflammation….the retest your four ion labs to see if you need to now raise your serum iron, which is impossible to do with inflammation pushing iron into storage.

Have Hashimoto’s?  Get those antibodies DOWN!

Need to do inflammation labs?  Go here and order your own!!



Important note: STTM is an information-only site based on what many patients worldwide have reported in their treatment and wisdom over the years. This is not to be taken as personal medical advice, nor to replace a relationship with your doctor. By reading this information-only website, you take full responsibility for what you choose to do with this website's information or outcomes. See the Disclaimer and Terms of Use.