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Warning!! STTM is about bat-guano crazy conspiracy theorists…and more Thyroid Tidbits!

ANNOUNCINGACELLA’S NP THYROID IS ON BACKORDER  

It’s a back-handed compliment. i.e. Acella‘s brand of Natural Desiccated Thyroid has been in great demand! But…success can equal problems, because they weren’t keeping up…or that’s how we understand it. So when you go back to get a refill, the pharmacist may try to put you another brand if they are already out. So hang tight. Acella states that they will be back into better production by the end of April.

DO YOU REALLY NEED COMPOUNDED DESICCATED THYROID?

Progressive doctors have been having a love-affair with compounded medications for several years. And for some medications, as well as for patients who are sensitive or allergic to certain fillers, it makes complete sense! (Compounded means that the pharmacist “combines, mixes, or alters ingredients in response to a prescription to create a medication tailored to the medical needs of an individual patient”).

But…most thyroid patients are discovering that they really do NOT need compounded NDT and that is especially true for “slow release” compounded NDT.  First, compounded NDT is far more expensive than the prescription brands. Second, the T4 in desiccated thyroid is your “natural slow release” of T3 throughout your day. So it makes financial sense to go with the prescription brands if you have no sensitivities or problems with fillers. And even if you go with compounded….you don’t need slow-release!

YES, THE STTM WEBSITE HAS BEEN UPDATED, plus more pages!

In case you didn’t notice, there’s a new look to STTM. Part of it is because we needed STTM to be far more user-friendly on your cell phones. I think you’ll like what you see. You’ll also find links at the TOP of each page instead of to the left.

There are also new pages from the last several weeks: one on parathyroid issues, especially hyperparathyroidism (i.e. if you have high calcium levels, you need to read this page); another is an issues related to hypo landing page showing you several conditions which can outright be related to your hypothyroidism and you may not even realize it (like fibromyalgia); another about problems that can occur if you overeat high oxalate foods (as happened to ME!); how hypothyroid patients can have low stomach acid and its consequences (like acid reflux and poor absorption issues)….and you can always keep up with What’s New on STTM.

ALL THE BUZZ ABOUT MTHFR

If you haven’t heard about it, you probably will. Because lots of thyroid patients are finding themselves with a defect in a particular gene called the MTHFR, which is the acronym for “methylenetetrahydrofolate reductase” gene (methyl-ene-tetra-hydro-folate-re-duc-tase). This gene is supposed to make the MTHFR enzyme. But if there’s a defect, the enzyme doesn’t work right and you can be left with a multitude of health issues (or see them in your ancestors) including heart disease (and high homocysteine levels), breast cancer, other cancers, addictions, miscarriages, chemical sensitivities, IBS, strokes and so much more. Those with this defect can also find themselves with high levels of mercury, or iron, or other toxins. Go here to read what it’s all about.

BERBERINE. INSULIN RESISTANCE, and THYROID CANCER

Since it’s pretty obvious to me that I have insulin resistance (i.e. it takes twice as much insulin to do the job, which means more fat storage), I was pretty excited when I learned about Berberine. It’s a natural alkaloid salt found in a variety of different plants and it’s stated to make your insulin more effective, thus your blood sugar levels can come down. I notice that some folks are using it in place of Metformin, as well, and reporting better glucose levels. It’s supposedly been used for centuries in Ayurvedic and Chinese medicine.

***But there’s another interesting possibility about Berberine: studies have shown it to be effective in reducing thyroid cancer cells, here. Talk to your doctor about it before assuming you can use it for cancer in lieu of other treatments, please.

AND ABOUT THE TITLE OF THIS BLOG POST...

Bet ya didn’t know that STTM is bat-guano crazy, did ya?? lol. This misinformed comment was found as a comment of a random blog post, and tells me that some still don’t get that this isn’t about conspiracy or theory. This is about patients worldwide who have either found that T4-only meds weren’t doing the job in their own degree and kind, or….patients were getting bit in the behind years later thanks to the inadequacy of thyroxine. Even worse, doctor who have been diagnosing or treating by the TSH pituitary hormone were leaving patients sick!

So what you have on STTM is more than ten years of GOOD patient experiences, the good and the bad. LEARN from it, and expect to take it into your doctor’s office to help them catch up with us!

STTM BOOK IS COMING SOON IN SPANISH  

First there was English, then came Swedish, then came German….and later, you’ll see Spanish! I’ll announce it when it’s out. I also plan on updating a few parts of the current revised STTM English book by Fall–just some corrections here or there. For example, the current one states that the percent saturation should be 25 – 45% for women, but we know that most women, when optimal, fall somewhere around 35% and definitely not 25%. So I’ll correct that, because somehow, it didn’t get in Addendum C of the current revised edition! Get your book here…and consider two or three, because your shipping rate is much better. Give the extras to a friend or loved one.

Hypothyroidism, Insulin resistance and Metformin: read this brilliant information!

This interesting page has been updated to the present day and time. Enjoy!

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The following insightful post was written by UK hypothyroid patient Sarah Wilson. 

My daughter (25) has epilepsy. What’s that got to do with being hypothyroid and Natural Thyroid Hormones (NTH. also known as Natural Desiccated Thyroid or NDT)? Quite a lot, by the look of things.

My daughter’s epilepsy is triggered by unstable blood sugars. And since taking Metformin (medication to improve blood sugar control), she has significantly reduced the number of seizures. Being a good hypothyroid Tiger-mother, I have been doing mega amounts of research and we got to the Metformin approach through reading hundreds of academic medical journals. What I found along the way got me thinking about NTH and Hypothyroidism.

I have a strong hunch, backed up by some meaty academic evidence, that when patients develop hypothyroid symptoms, they are actually becoming insulin resistant. There are many symptoms in common between women with PCOS and hypothyroidism–the hair loss, the weight gain, et al. http://insulinhub.hubpages.com/hub/PCOS-and-Hypothyroidism A hypothyroid person’s body thinks it is going into starvation mode and so, to preserve resources and prolong life, the metabolism changes. If hypothyroid is prolonged or pronounced, then it is entirely feasible that even with the reintroduction of thyroid hormones, that chemical preservation mode becomes permanent. To get back to normal, they need a super “jump-start” to kick the metabolism back into action. The super-kick start is effected through something called AMPK, which is known as the “master metabolic regulating enzyme.”  http://en.wikipedia.org/wiki/AMP-activated_protein_kinase

Guess what? This is exactly what happens to Diabetes patients when Metformin is introduced. http://en.wikipedia.org/wiki/Metformin

If you are technically minded then you might want to read these articles. http://www.springerlink.com/content/r81606gl3r603167/ and http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2011.04029.x/pdf

They are a bit tough-going on the science but worth ploughing through. Why?  Note the following comments/partial statements:  “Hypothyroidism is characterized by decreased insulin responsiveness”; “the pivotal regulatory role of T3 in major metabolic pathways”; “The effect of thyroid hormone on basal metabolic rate was recognized more than a century ago”

The community knows that T3/NTH makes hypothyroid patients feel better – but the medical establishment is scared of T3/NTH – probably because they don’t understand how it really works. The medical establishment might find an alternative line of argument about impaired metabolism more palatable if we can show them this real proof that the old desiccated thryoid treatment **was/is** having the right result – the i.e. the T3 is jump-starting the metabolism by re-activating AMPK. If Metformin (or one of the other anti-diabetic meds) could actually also do the same thing for hypothyroidism without the “dangers” of NTH, they they should be jumping at the opportunity.

The great news is that Metformin is very cheap, stable and has very few serious side effects (and certainly none on the heart). To use the car engine metaphor, if glucose is our petrol, AMPK is the spark plug and both T3 and Metformin are both ignition switches. Sometimes if you have flat batteries in the car, it doesn’t matter how much you turn the ignition switch or pump the petrol pedal, all it does is flatten the battery and flood the engine. Dr. Skinner in the UK has been treating “pre-hypothyroidism” the way that some doctors treat “pre-diabetes”. Those hypothyroid patients who get treated early (before the wretched blood numbers get into the magical range) probably haven’t had their AMPK pathways altered and the T4-T3 conversion still works. The use of drugs as prophylactics is well understood by the medical establishment (e.g. baby aspirin for hearts), so there is no reason therefore why thyroid hormone replacement therapy shouldn’t logically be given to ward off a greater problem down the line.

It’s my belief that there is clear and abundant academic evidence that the AMPK/Metformin research should branch out to also look at thyroid disease.

As a supplementary on the history. I have PCOS; my female relatives have PCOS; my mother has just developed breast cancer which we are certain is related to the oestrogen dominance/insulin resistance. My daughter also has had Coeliac Disease since weaning (and oh boy, that was a fight to get a diagnosis but we got there). My daughter was showing lots of PCOS symptoms (some of which are of course hypothyroid symptoms) alongside the Estrogen, but because there were no cysts…no diagnosis, which is not correct by the Amsterdam criteria, but there we have it. So we moved “off topic” in PCOS terms, did a 9 month experiment of adding and subtracting one thing at a time to get to a (more) stable outcome. We never got the PCOS diagnosis but we did end up with T2DM Type 2 Diabetes) by the backdoor and the Metformin. We had two stupid consultants who reduced her to tears – their logic was unbelievably crass and at odds with long standing proof: “there isn’t a tap in your neck which stops the sugar getting to your brain you know” grrrrr. I have since found the links between people with T1DM (Type 1 Diabetes) who inject insulin and hypothyroidism too.

So my idea is that we need to talk to the medical profession in a language they relate to. They think Natural Desiccated Thyroid is voodoo, so they switch off. YET the NDT is doing something very, very scientific: the direct T3 is kicking the closed -own metabolic process back into life, just like Metformin does for insulin resistance. Who says there isn’t more widespread T4 resistance? There is serotonin resistance!  http://www.ncbi.nlm.nih.gov/pubmed/17250776

http://web.archive.org/web/20130426233947/http://www.hotthyroidology.com/editorial_79.html Take a look at page 63.

Disclaimer: I, Sarah, am not medically trained and I haven’t even got a University degree. My business, however, is researching complex financial data and since leaving school, I have probably graduated with a PhD in the University of Life. My daughter has two degrees and my husband is in IT so I’ve learned a lot about logic over the past 30 years. I think that to take this debate forward, we need someone with the credibility to do a piece of academic research and get it put into one of the highly ranked journals – even doing a relatively straightforward meta-analysis of all the published works on AMPK/T3 /metabolism would be a start. I know everyone feels desperately miserable about not being treated properly, and it is probably very sexist that us bunch of moaning women are not taken seriously. BUT perception is reality and we have to deal with that reality as best we can. And I think that our sisters in the chronic fatigue/ME camp should have reason to join us on our quest too. I wouldn’t know where to start to find out how to sponsor a university researcher but maybe we should think about that as our “big thing”.

Let’s talk.